Cirbp (cold inducible RNA binding protein) - Rat Genome Database

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Gene: Cirbp (cold inducible RNA binding protein) Rattus norvegicus
Analyze
Symbol: Cirbp (Ensembl: Dazap1)
Name: cold inducible RNA binding protein (Ensembl:DAZ associated protein 1)
RGD ID: 620756
Description: Predicted to enable RNA binding activity and translation repressor activity. Predicted to be involved in positive regulation of gene expression; response to UV; and stress granule assembly. Predicted to act upstream of or within cellular response to cold; negative regulation of cell growth; and regulation of cell cycle G1/S phase transition. Predicted to be located in cytoplasmic stress granule and nucleoplasm. Predicted to be part of spliceosomal complex. Orthologous to human CIRBP (cold inducible RNA binding protein); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A18 hnRNP; cold inducible RNA-binding protein; cold-inducible RNA-binding protein; glycine-rich RNA-binding protein CIRP
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,184,515 - 10,189,623 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.279,533,857 - 9,538,899 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,424,178 - 9,538,818 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx712,416,829 - 12,421,790 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,292,168 - 14,297,129 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,153,260 - 12,158,220 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,400,066 - 12,405,054 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,401,207 - 12,405,022 (-)Ensemblrn6Rnor6.0
Rnor_5.0712,570,171 - 12,575,155 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4711,047,003 - 11,050,820 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera77,711,175 - 7,714,992 (-)NCBICelera
RGSC_v3.1711,047,003 - 11,050,820 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
(S)-nicotine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methylcholine  (ISO)
3',5'-cyclic UMP  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetazolamide  (ISO)
aconitine  (EXP)
acrylamide  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CCCP  (ISO)
chloroethene  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP,ISO)
chrysene  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dimethylarsinic acid  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
folpet  (ISO)
FR900359  (ISO)
gallic acid  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
imidacloprid  (EXP)
indole-3-methanol  (EXP)
isoprenaline  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
maneb  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
morphine  (ISO)
nicotine  (ISO)
ochratoxin A  (EXP,ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
potassium chloride  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium azide  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO,ISS)
cytoplasmic stress granule  (ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (ISO,ISS)
spliceosomal complex  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cold-inducible RNA-binding protein maintains intestinal barrier during deep hypothermic circulatory arrest. Li Y, etal., Interact Cardiovasc Thorac Surg. 2019 Oct 1;29(4):583-591. doi: 10.1093/icvts/ivz147.
3. Endotoxin-induced inhibition of growth hormone receptor signaling in rat liver in vivo. Mao Y, etal., Endocrinology 1999 Dec;140(12):5505-15.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Effects of ischemia and H2O2 on the cold stress protein CIRP expression in rat neuronal cells. Xue JH, etal., Free Radic Biol Med 1999 Dec;27(11-12):1238-44.
Additional References at PubMed
PMID:9151692   PMID:11574538   PMID:16513844   PMID:16791210   PMID:17967451   PMID:20546708   PMID:22297174   PMID:22658674   PMID:22681889   PMID:24097189   PMID:25953924   PMID:26327811  
PMID:26936526   PMID:26995407   PMID:27477308   PMID:28131823   PMID:31116410   PMID:31564537   PMID:31918003   PMID:32184914   PMID:32212953   PMID:33755319   PMID:38539067   PMID:38807464  


Genomics

Comparative Map Data
Cirbp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,184,515 - 10,189,623 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.279,533,857 - 9,538,899 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,424,178 - 9,538,818 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx712,416,829 - 12,421,790 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,292,168 - 14,297,129 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,153,260 - 12,158,220 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,400,066 - 12,405,054 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,401,207 - 12,405,022 (-)Ensemblrn6Rnor6.0
Rnor_5.0712,570,171 - 12,575,155 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4711,047,003 - 11,050,820 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera77,711,175 - 7,714,992 (-)NCBICelera
RGSC_v3.1711,047,003 - 11,050,820 (-)NCBI
Cytogenetic Map7q11NCBI
CIRBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,269,332 - 1,274,880 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,259,384 - 1,274,880 (+)Ensemblhg38GRCh38
GRCh37191,269,331 - 1,274,879 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,220,345 - 1,224,169 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34191,220,346 - 1,224,169NCBI
Celera191,203,500 - 1,209,041 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef191,043,361 - 1,048,903 (+)NCBIHuRef
CHM1_1191,269,508 - 1,275,049 (+)NCBICHM1_1
T2T-CHM13v2.0191,237,856 - 1,243,403 (+)NCBIT2T-CHM13v2.0
Cirbp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,001,824 - 80,008,620 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,001,819 - 80,008,620 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381080,165,990 - 80,172,786 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,165,985 - 80,172,786 (+)Ensemblmm10GRCm38
MGSCv371079,630,586 - 79,634,398 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361079,570,970 - 79,574,782 (+)NCBIMGSCv36mm8
Celera1081,182,697 - 81,186,512 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Cirbp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,634,394 - 6,640,800 (-)Ensembl
ChiLan1.0NW_0049554956,634,389 - 6,640,800 (-)NCBIChiLan1.0ChiLan1.0
CIRBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,603,594 - 5,617,227 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,840,212 - 4,853,816 (+)NCBINHGRI_mPanPan1
CIRBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,521,609 - 57,526,526 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,519,119 - 57,526,435 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2057,324,633 - 57,337,238 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02058,264,537 - 58,277,141 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,262,145 - 58,269,372 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,320,366 - 57,332,961 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,799,639 - 57,812,241 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,002,628 - 58,015,240 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cirbp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,195,219 - 217,199,061 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588636,026 - 640,409 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936588636,041 - 639,564 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CIRBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,189,846 - 77,195,569 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1277,185,295 - 77,194,373 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,835,324 - 77,844,392 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CIRBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.161,037,389 - 1,043,265 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl61,039,401 - 1,042,187 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660817,820,188 - 7,826,057 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cirbp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,401,456 - 7,409,408 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248287,401,123 - 7,409,275 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cirbp
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11154,702,199 - 154,708,441 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cirbp
22 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:97
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000021648
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
Cirbp-rs1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.279,535,076 - 9,535,266 (+)MAPPERmRatBN7.2
Rnor_6.0712,401,282 - 12,401,471NCBIRnor6.0
Rnor_5.0712,571,387 - 12,571,576UniSTSRnor5.0
RGSC_v3.4711,047,080 - 11,047,269UniSTSRGSC3.4
Celera77,711,252 - 7,711,441UniSTS
Cytogenetic Map7q11UniSTS
RH125133  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.279,535,143 - 9,535,265 (+)MAPPERmRatBN7.2
Rnor_6.0712,401,349 - 12,401,470NCBIRnor6.0
Rnor_5.0712,571,454 - 12,571,575UniSTSRnor5.0
RGSC_v3.4711,047,147 - 11,047,268UniSTSRGSC3.4
Celera77,711,319 - 7,711,440UniSTS
Cytogenetic Map7q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000021648   ⟹   ENSRNOP00000021648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,535,009 - 9,538,818 (-)Ensembl
Rnor_6.0 Ensembl712,401,207 - 12,405,022 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000046886   ⟹   ENSRNOP00000046032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,074,849 - 10,095,599 (-)Ensembl
mRatBN7.2 Ensembl79,424,180 - 9,444,929 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100123   ⟹   ENSRNOP00000090669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,074,849 - 10,087,882 (-)Ensembl
mRatBN7.2 Ensembl79,424,178 - 9,448,078 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101444   ⟹   ENSRNOP00000088612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,424,180 - 9,536,880 (-)Ensembl
RefSeq Acc Id: NM_031147   ⟹   NP_112409
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,185,658 - 10,189,475 (-)NCBI
mRatBN7.279,535,000 - 9,538,818 (-)NCBI
Rnor_6.0712,401,205 - 12,405,022 (-)NCBI
Rnor_5.0712,570,171 - 12,575,155 (-)NCBI
RGSC_v3.4711,047,003 - 11,050,820 (-)RGD
Celera77,711,175 - 7,714,992 (-)RGD
Sequence:
RefSeq Acc Id: NR_172713
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,184,515 - 10,189,475 (-)NCBI
mRatBN7.279,533,857 - 9,538,818 (-)NCBI
RefSeq Acc Id: NR_172714
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,184,515 - 10,189,475 (-)NCBI
mRatBN7.279,533,857 - 9,538,818 (-)NCBI
RefSeq Acc Id: XM_006241015   ⟹   XP_006241077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,185,658 - 10,189,623 (-)NCBI
mRatBN7.279,533,857 - 9,538,899 (-)NCBI
Rnor_6.0712,400,066 - 12,405,054 (-)NCBI
Rnor_5.0712,570,171 - 12,575,155 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079945   ⟹   XP_038935873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,185,658 - 10,189,527 (-)NCBI
mRatBN7.279,535,599 - 9,538,870 (-)NCBI
RefSeq Acc Id: XM_063264303   ⟹   XP_063120373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,185,658 - 10,189,556 (-)NCBI
RefSeq Acc Id: NP_112409   ⟸   NM_031147
- UniProtKB: P60825 (UniProtKB/Swiss-Prot),   A6K8P8 (UniProtKB/TrEMBL),   Q6NT88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241077   ⟸   XM_006241015
- Peptide Label: isoform X2
- UniProtKB: P60825 (UniProtKB/Swiss-Prot),   A6K8P8 (UniProtKB/TrEMBL),   Q6NT88 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021648   ⟸   ENSRNOT00000021648
RefSeq Acc Id: XP_038935873   ⟸   XM_039079945
- Peptide Label: isoform X1
- UniProtKB: A6K8P9 (UniProtKB/TrEMBL),   Q6NT88 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088612   ⟸   ENSRNOT00000101444
Ensembl Acc Id: ENSRNOP00000090669   ⟸   ENSRNOT00000100123
Ensembl Acc Id: ENSRNOP00000046032   ⟸   ENSRNOT00000046886
RefSeq Acc Id: XP_063120373   ⟸   XM_063264303
- Peptide Label: isoform X1
- UniProtKB: A6K8P9 (UniProtKB/TrEMBL),   Q6NT88 (UniProtKB/TrEMBL)
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P60825-F1-model_v2 AlphaFold P60825 1-172 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695031
Promoter ID:EPDNEW_R5555
Type:single initiation site
Name:Cirbp_1
Description:cold inducible RNA binding protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0712,405,022 - 12,405,082EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620756 AgrOrtholog
BioCyc Gene G2FUF-34920 BioCyc
Ensembl Genes ENSRNOG00000015999 Ensembl
  ENSRNOG00000031387 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000088478 ENTREZGENE
Ensembl Transcript ENSRNOT00000021648.7 UniProtKB/Swiss-Prot
  ENSRNOT00000162080 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6888887 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RBM UniProtKB/Swiss-Prot
  RBM3/CIRBP_RRM UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
  RRM_dom_euk UniProtKB/Swiss-Prot
KEGG Report rno:81825 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72781 IMAGE-MGC_LOAD
NCBI Gene 81825 ENTREZGENE
PANTHER TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED UniProtKB/Swiss-Prot
Pfam RRM_1 UniProtKB/Swiss-Prot
PhenoGen Cirbp PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015999 RatGTEx
  ENSRNOG00000031387 RatGTEx
  ENSRNOG00000088478 RatGTEx
SMART RRM UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
UniProt A0ABK0M6T6_RAT UniProtKB/TrEMBL
  A6K8P4_RAT UniProtKB/TrEMBL
  A6K8P5_RAT UniProtKB/TrEMBL
  A6K8P8 ENTREZGENE, UniProtKB/TrEMBL
  A6K8P9 ENTREZGENE, UniProtKB/TrEMBL
  CIRBP_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6NT88 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O09069 UniProtKB/Swiss-Prot
  O09148 UniProtKB/Swiss-Prot
  Q61413 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Cirbp  cold inducible RNA binding protein    cold inducible RNA-binding protein  Name updated 1299863 APPROVED
2002-08-07 Cirbp  cold inducible RNA-binding protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression ubiquitously expressed 724747