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Gene: Ctnnd2 (catenin delta 2) Rattus norvegicus

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Symbol:

Ctnnd2

Name:

catenin delta 2

RGD ID:

620734

Description:

A structural constituent of postsynaptic density. Involved in neuron projection retraction; positive regulation of axon extension; and regulation of postsynaptic membrane neurotransmitter receptor levels. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in anxiety disorder; major depressive disorder; and schizophrenia. Orthologous to human CTNND2 (catenin delta 2); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

catenin (cadherin-associated protein), delta 2; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein); catenin delta-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	82,879,469 - 83,727,409 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	82,879,469 - 83,727,409 (+)	Ensembl				GRCr8
mRatBN7.2	2	81,168,525 - 82,016,495 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	81,167,117 - 82,015,764 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	88,378,864 - 89,064,522 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	86,500,610 - 87,186,098 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	81,556,878 - 82,242,356 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	83,227,247 - 84,094,315 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	83,393,282 - 84,094,315 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	103,069,807 - 103,768,936 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	82,238,091 - 83,088,901 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	76,879,503 - 77,545,735 (+)	NCBI		Celera
RGSC_v3.1	2	82,788,377 - 82,926,463 (+)	NCBI
Cytogenetic Map	2	q22-q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

anxiety disorder (ISO)

developmental and epileptic encephalopathy 11 (ISO)

genetic disease (ISO)

glioblastoma (ISO)

major depressive disorder (ISO)

Neoplastic Cell Transformation (ISO)

Neurodevelopmental Disorders (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,3,5-trinitro-1,3,5-triazinane (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

Butylbenzyl phthalate (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chromium(6+) (ISO)

cocaine (EXP,ISO)

copper atom (EXP)

copper(0) (EXP)

coumestrol (ISO)

cyclophosphamide (ISO)

dibenz[a,h]anthracene (ISO)

dimethylarsinic acid (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenvalerate (EXP)

fonofos (ISO)

genistein (ISO)

mercury dibromide (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

nickel atom (ISO)

p-chloromercuribenzoic acid (ISO)

paclitaxel (ISO)

panobinostat (ISO)

paracetamol (ISO)

paraquat (ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

progesterone (ISO)

propanal (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

terbufos (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

triptonide (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

cell-cell adhesion (IEA)

dendritic spine morphogenesis (IEA,ISO)

DNA-templated transcription (IEA)

learning (ISO)

maintenance of postsynaptic density structure (IEA)

morphogenesis of a branching structure (ISO)

neuron projection retraction (IMP)

positive regulation of axon extension (IMP)

regulation of canonical Wnt signaling pathway (IEA,ISO)

regulation of postsynaptic membrane neurotransmitter receptor levels (IDA,IEP,IMP)

regulation of synaptic plasticity (ISO)

synapse organization (IEA,ISO)

Cellular Component

adherens junction (IEA)

anchoring junction (IEA)

cell junction (IEA)

dendrite (IEA)

glutamatergic synapse (IDA,IEP,IMP)

nucleus (IEA)

organelle (IEA)

perikaryon (IEA,ISO,ISS)

postsynaptic density (IDA,IEP,ISO)

Molecular Function

beta-catenin binding (IEA,ISO)

protein binding (IPI,ISO)

structural constituent of postsynaptic density (IDA,IEP,IMP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal axon extension (IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.	Deguchi M, etal., J Biol Chem 2000 Sep 22;275(38):29875-80.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Interaction of S-SCAM with neural plakophilin-related Armadillo-repeat protein/delta-catenin.	Ide N, etal., Biochem Biophys Res Commun. 1999 Mar 24;256(3):456-61.
5.	Glutamate-induced delta-catenin redistribution and dissociation from postsynaptic receptor complexes.	Jones SB, etal., Neuroscience. 2002;115(4):1009-21.
6.	δ-Catenin engages the autophagy pathway to sculpt the developing dendritic arbor.	Ligon C, etal., J Biol Chem. 2020 Aug 7;295(32):10988-11001. doi: 10.1074/jbc.RA120.013058. Epub 2020 Jun 17.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	Further confirmation of the association between anxiety and CTNND2: replication in humans.	Nivard MG, etal., Genes Brain Behav. 2014 Feb;13(2):195-201. doi: 10.1111/gbb.12095. Epub 2013 Nov 21.
10.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
11.	GOA pipeline	RGD automated data pipeline
12.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
14.	Synaptic anchorage of AMPA receptors by cadherins through neural plakophilin-related arm protein AMPA receptor-binding protein complexes.	Silverman JB, etal., J Neurosci. 2007 Aug 8;27(32):8505-16. doi: 10.1523/JNEUROSCI.1395-07.2007.

Additional References at PubMed

PMID:15380068	PMID:17097608	PMID:17114649	PMID:20623542	PMID:22022388	PMID:25724647	PMID:25807484

Genomics

Comparative Map Data

Ctnnd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	82,879,469 - 83,727,409 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	82,879,469 - 83,727,409 (+)	Ensembl				GRCr8
mRatBN7.2	2	81,168,525 - 82,016,495 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	81,167,117 - 82,015,764 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	88,378,864 - 89,064,522 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	86,500,610 - 87,186,098 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	81,556,878 - 82,242,356 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	83,227,247 - 84,094,315 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	83,393,282 - 84,094,315 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	103,069,807 - 103,768,936 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	82,238,091 - 83,088,901 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	76,879,503 - 77,545,735 (+)	NCBI		Celera
RGSC_v3.1	2	82,788,377 - 82,926,463 (+)	NCBI
Cytogenetic Map	2	q22-q23	NCBI

CTNND2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	10,971,836 - 11,904,446 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	10,971,836 - 11,904,446 (-)	Ensembl			hg38	GRCh38
GRCh37	5	10,971,948 - 11,904,558 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	11,024,952 - 11,957,110 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	11,024,951 - 11,957,110	NCBI
Celera	5	11,009,117 - 11,940,384 (-)	NCBI		Celera
Cytogenetic Map	5	p15.2	NCBI
HuRef	5	10,955,380 - 11,886,519 (-)	NCBI		HuRef
CHM1_1	5	10,971,878 - 11,903,969 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	10,909,469 - 11,841,846 (-)	NCBI		T2T-CHM13v2.0

Ctnnd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	30,172,680 - 31,029,490 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	30,172,739 - 31,029,487 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	30,172,534 - 31,029,344 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	30,172,593 - 31,029,341 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	30,102,348 - 30,959,099 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	30,117,182 - 30,972,978 (+)	NCBI		MGSCv36	mm8
Celera	15	30,892,803 - 31,737,347 (+)	NCBI		Celera
Cytogenetic Map	15	B2	NCBI
cM Map	15	12.02	NCBI

Ctnnd2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	636,225 - 1,350,784 (-)	Ensembl
ChiLan1.0	NW_004955426	635,287 - 1,007,389 (-)	NCBI	ChiLan1.0	ChiLan1.0

CTNND2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	11,218,251 - 12,156,782 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	9,371,858 - 10,310,393 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	11,288,652 - 12,227,569 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	11,137,843 - 11,553,313 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

CTNND2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	2,521,730 - 3,438,218 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	2,521,724 - 3,437,292 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	7,025,336 - 7,942,431 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	2,424,759 - 3,340,469 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	2,424,198 - 3,340,469 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	2,482,252 - 3,394,692 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	2,452,724 - 3,371,552 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	2,689,314 - 3,602,824 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ctnnd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	235,603,479 - 236,456,778 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936643	2,946,899 - 3,358,093 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936643	2,945,994 - 3,799,321 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CTNND2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	508,637 - 1,521,749 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	16	508,630 - 1,521,773 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	241,808 - 523,553 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CTNND2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	10,499,822 - 11,426,432 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	10,500,761 - 10,762,677 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666064	17,117,009 - 18,045,253 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ctnnd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	8,161,442 - 9,049,685 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624751	8,160,520 - 9,049,871 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ctnnd2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	149,788,323 - 150,184,779 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ctnnd2
6515 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	20
Count of miRNA genes:	17
Interacting mature miRNAs:	20
Transcripts:	ENSRNOT00000044871
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578777	Stresp15	Stress response QTL 15	2	0.05	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	2	61556902	106556902	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1598865	Bp296	Blood pressure QTL 296	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	82947902	127947902	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
152025242	Bw191	Body weight QTL 191	3.62		body mass (VT:0001259)		2	40306867	124537199	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
61465	Bp13	Blood pressure QTL 13	3.3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	78269809	104744824	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	41801363	104744824	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
631208	Bw1	Body weight QTL1	5.09		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	2	44904355	85286097	Rat
2317058	Aia13	Adjuvant induced arthritis QTL 13	2.9		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	2	78269809	123269809	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1300155	Bp174	Blood pressure QTL 174	4.09		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	44537979	112567334	Rat
5684990	Bmd82	Bone mineral density QTL 82	2.8		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	2	61051541	105724065	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1359034	Bp274	Blood pressure QTL 274			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	51266859	96266859	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
631500	Bp99	Blood pressure QTL 99	2.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	61051883	104684275	Rat
61392	Bp6	Blood pressure QTL 6	7		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	82214549	127214549	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
5684996	Bmd85	Bone mineral density QTL 85	4.7	0.024	tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	2	61051541	105724065	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	159440891	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	83465677	Rat
1558648	Smcn1	Smooth muscle cell number QTL 1		0.039	blood vessel smooth muscle cell quantity (VT:0010525)	aorta smooth muscle cell count per unit vessel length (CMO:0001646)	2	60861391	105861391	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
2306903	Bp336	Blood pressure QTL 336		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	38426449	111295694	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	44904355	89904355	Rat
61438	Cia7	Collagen induced arthritis QTL 7	4.6	0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	2	61051541	143746880	Rat

Markers in Region

D2Rat212

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	2	83,400,752 - 83,400,870 (+)	Marker Load Pipeline
mRatBN7.2	2	81,689,826 - 81,689,944 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,754,907 - 83,755,024	NCBI	Rnor6.0
Rnor_5.0	2	103,429,722 - 103,429,839	UniSTS	Rnor5.0
RGSC_v3.4	2	82,761,369 - 82,761,486	UniSTS	RGSC3.4
RGSC_v3.4	2	82,761,368 - 82,761,486	RGD	RGSC3.4
Celera	2	77,224,707 - 77,224,820	UniSTS
RGSC_v3.1	2	82,706,236 - 82,706,562	RGD
SHRSP x BN Map	2	33.1798	RGD
SHRSP x BN Map	2	33.1798	UniSTS
Cytogenetic Map	2	q22	UniSTS

D2Rat211

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	2	83,540,845 - 83,541,048 (+)	Marker Load Pipeline
mRatBN7.2	2	81,829,923 - 81,830,126 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,908,790 - 83,908,992	NCBI	Rnor6.0
Rnor_5.0	2	103,583,241 - 103,583,443	UniSTS	Rnor5.0
RGSC_v3.4	2	82,901,478 - 82,901,680	UniSTS	RGSC3.4
RGSC_v3.4	2	82,901,477 - 82,901,680	RGD	RGSC3.4
Celera	2	77,362,615 - 77,362,817	UniSTS
RGSC_v3.1	2	82,846,433 - 82,846,743	RGD
SHRSP x BN Map	2	33.0998	RGD
SHRSP x BN Map	2	33.0998	UniSTS
Cytogenetic Map	2	q22	UniSTS

D2Rat275

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	2	83,465,462 - 83,465,677 (+)	Marker Load Pipeline
mRatBN7.2	2	81,754,530 - 81,754,745 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,819,608 - 83,819,822	NCBI	Rnor6.0
Rnor_5.0	2	103,494,092 - 103,494,306	UniSTS	Rnor5.0
RGSC_v3.4	2	82,826,123 - 82,826,337	UniSTS	RGSC3.4
RGSC_v3.4	2	82,826,122 - 82,826,336	RGD	RGSC3.4
Celera	2	77,289,347 - 77,289,561	UniSTS
RGSC_v3.1	2	82,771,084 - 82,771,298	RGD
RH 3.4 Map	1	1611.2	RGD
RH 3.4 Map	1	1611.2	UniSTS
SHRSP x BN Map	2	33.0998	UniSTS
SHRSP x BN Map	2	33.0998	RGD
Cytogenetic Map	2	q22	UniSTS

D2Rat324

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	2	83,685,121 - 83,685,222 (+)	Marker Load Pipeline
mRatBN7.2	2	81,974,206 - 81,974,307 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	84,052,777 - 84,052,877	NCBI	Rnor6.0
Rnor_5.0	2	103,727,228 - 103,727,328	UniSTS	Rnor5.0
RGSC_v3.4	2	83,047,314 - 83,047,414	UniSTS	RGSC3.4
RGSC_v3.4	2	83,047,313 - 83,047,414	RGD	RGSC3.4
Celera	2	77,504,145 - 77,504,245	UniSTS
RGSC_v3.1	2	82,992,275 - 82,992,376	RGD
SHRSP x BN Map	2	33.1798	RGD
SHRSP x BN Map	2	33.1798	UniSTS
Cytogenetic Map	2	q22	UniSTS

D2Got33

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	81,956,908 - 81,957,137 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	84,035,480 - 84,035,708	NCBI	Rnor6.0
Rnor_5.0	2	103,709,931 - 103,710,159	UniSTS	Rnor5.0
RGSC_v3.4	2	83,030,016 - 83,030,244	UniSTS	RGSC3.4
RGSC_v3.4	2	83,030,015 - 83,030,244	RGD	RGSC3.4
RGSC_v3.1	2	82,974,978 - 82,975,206	RGD
RH 3.4 Map	2	516.2	RGD
RH 3.4 Map	2	516.2	UniSTS
RH 2.0 Map	2	417.8	RGD
Cytogenetic Map	2	q22	UniSTS

D2Got41

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	81,891,408 - 81,891,603 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,970,452 - 83,970,646	NCBI	Rnor6.0
Rnor_5.0	2	103,644,903 - 103,645,097	UniSTS	Rnor5.0
RGSC_v3.4	2	82,963,909 - 82,964,103	UniSTS	RGSC3.4
RGSC_v3.4	2	82,963,910 - 82,964,103	RGD	RGSC3.4
Celera	2	77,421,814 - 77,422,008	UniSTS
RGSC_v3.1	2	82,908,872 - 82,909,065	RGD
RH 3.4 Map	2	517.0	UniSTS
RH 3.4 Map	2	517.0	RGD
RH 2.0 Map	2	420.2	RGD
Cytogenetic Map	2	q22	UniSTS

BE120970

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	81,515,921 - 81,516,071 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,580,909 - 83,581,058	NCBI	Rnor6.0
Rnor_5.0	2	103,256,372 - 103,256,521	UniSTS	Rnor5.0
RGSC_v3.4	2	82,586,977 - 82,587,126	UniSTS	RGSC3.4
Celera	2	77,054,180 - 77,054,329	UniSTS
RH 3.4 Map	2	368.7	UniSTS
Cytogenetic Map	2	q22	UniSTS

D5S2317

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	82,015,560 - 82,015,659 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	84,094,112 - 84,094,210	NCBI	Rnor6.0
Rnor_5.0	2	103,768,733 - 103,768,831	UniSTS	Rnor5.0
RGSC_v3.4	2	83,088,702 - 83,088,800	UniSTS	RGSC3.4
Celera	2	77,545,532 - 77,545,630	UniSTS
Cytogenetic Map	2	q22	UniSTS

RH128575

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	82,015,402 - 82,015,613 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	84,093,954 - 84,094,164	NCBI	Rnor6.0
Rnor_5.0	2	103,768,575 - 103,768,785	UniSTS	Rnor5.0
RGSC_v3.4	2	83,088,544 - 83,088,754	UniSTS	RGSC3.4
Celera	2	77,545,374 - 77,545,584	UniSTS
RH 3.4 Map	2	516.3	UniSTS
Cytogenetic Map	2	q22	UniSTS

BE101962

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	2	83,359,403 - 83,359,589 (+)	Marker Load Pipeline
mRatBN7.2	2	81,648,475 - 81,648,661 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,713,554 - 83,713,739	NCBI	Rnor6.0
Rnor_5.0	2	103,388,391 - 103,388,576	UniSTS	Rnor5.0
RGSC_v3.4	2	82,719,534 - 82,719,719	UniSTS	RGSC3.4
Celera	2	77,183,426 - 77,183,611	UniSTS
RH 3.4 Map	2	370.1	UniSTS
Cytogenetic Map	2	q22	UniSTS

BF386798

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	81,498,993 - 81,499,191 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,564,032 - 83,564,229	NCBI	Rnor6.0
Rnor_5.0	2	103,240,459 - 103,240,656	UniSTS	Rnor5.0
RGSC_v3.4	2	82,570,000 - 82,570,197	UniSTS	RGSC3.4
Celera	2	77,043,701 - 77,043,898	UniSTS
RH 3.4 Map	2	364.82	UniSTS
Cytogenetic Map	2	q22	UniSTS

BE102128

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	81,611,488 - 81,611,670 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,676,910 - 83,677,091	NCBI	Rnor6.0
Rnor_5.0	2	103,351,747 - 103,351,928	UniSTS	Rnor5.0
RGSC_v3.4	2	82,682,642 - 82,682,823	UniSTS	RGSC3.4
Celera	2	77,148,452 - 77,148,633	UniSTS
RH 3.4 Map	2	370.3	UniSTS
Cytogenetic Map	2	q22	UniSTS

AU047732

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	81,414,906 - 81,415,196 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,479,816 - 83,480,105	NCBI	Rnor6.0
Rnor_5.0	2	103,156,342 - 103,156,631	UniSTS	Rnor5.0
RGSC_v3.4	2	82,485,588 - 82,485,877	UniSTS	RGSC3.4
Celera	2	76,960,645 - 76,960,934	UniSTS
Cytogenetic Map	2	q22	UniSTS

RH137492

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	82,010,892 - 82,011,104 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	84,089,476 - 84,089,687	NCBI	Rnor6.0
Rnor_5.0	2	103,763,884 - 103,764,095	UniSTS	Rnor5.0
RGSC_v3.4	2	83,084,000 - 83,084,211	UniSTS	RGSC3.4
Celera	2	77,540,941 - 77,541,152	UniSTS
Cytogenetic Map	2	q22	UniSTS

AU049514

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	81,825,575 - 81,825,865 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	83,904,444 - 83,904,731	NCBI	Rnor6.0
Rnor_5.0	2	103,578,895 - 103,579,182	UniSTS	Rnor5.0
RGSC_v3.4	2	82,897,132 - 82,897,419	UniSTS	RGSC3.4
Celera	2	77,358,269 - 77,358,556	UniSTS
Cytogenetic Map	2	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	7	57	163	72	71	40	56	40	6	278	144	11	142	78	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001271502	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001415019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB008752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000044871 ⟹ ENSRNOP00000045121

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	82,879,469 - 83,727,409 (+)	Ensembl
mRatBN7.2 Ensembl	2	81,167,117 - 82,015,764 (+)	Ensembl
Rnor_6.0 Ensembl	2	83,393,282 - 84,094,315 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119467 ⟹ ENSRNOP00000096253

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	82,879,469 - 83,727,409 (+)	Ensembl
mRatBN7.2 Ensembl	2	81,167,117 - 82,015,764 (+)	Ensembl

RefSeq Acc Id:

NM_001271502 ⟹ NP_001258431

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	82,879,469 - 83,727,409 (+)	NCBI
mRatBN7.2	2	81,168,525 - 82,016,495 (+)	NCBI
Rnor_6.0	2	83,393,282 - 84,094,315 (+)	NCBI
Rnor_5.0	2	103,069,807 - 103,768,936 (+)	NCBI
Celera	2	76,879,503 - 77,545,735 (+)	NCBI

Sequence:

show sequence

ATGCCTGTCCCAGACCAGCCTCCGTCAGCCTCTGAGAAGAACAGCTCCTTGAGCCCAGGCTTAA
ACACCTCCAATGGGGATGGCTCTGAGACAGAAACAACCTCTGCTATCCTTGCCTCCGTCAAAGA
ACAGGAATTACAGTTTGAAAGGCTGACCCGAGAGCTGGAGGCTGAACGCCAGATCGTGGCCAGC
CAGCTGGAGAGATGCAAGCTTGGCTCCGAGACAGGAAGCATGAGCAGCATCAGTTCAGCAGGAG
AGCAGTTTCATTGGCAGACACAAGATGGCCAAAAAGACATCGAAGATGAACTCACAACAGGCCT
TGAGCTGGTGGACTCCTGCATCCGCTCTCTGCAGGAGTCAGGCATTCTTGACCCACAGGATTAC
TCCACAAGTGAAAGGCCCAGCCTGCTCTCCCAGAGTGCACTTCAGCTCAATTCCAAACCTGAAG
GGTCTTTCCAGTATCCGGCCAGCTACCATAGCAACCAGACCCTGGCCCTGGGTGACACAGCCCC
TTCTCAGCTCCCAGCACGCAGCACGCAAGCCCGAGCTGCCGGACAGAGCTTCAGCCAGGGCACG
ACCGGTCGCTCGGGGCACCTGGCGGGCTCCGAGCCTGCGCCACCGCCTCCGCCTCCGCGGGAGC
CCTTCGCGCCCAGCCTGGGCAGCGCTTTCCACCTGCCCGACGCGCCGCCCGCCGCCGCGGCGCT
CTACTACTCCAGCTCCACGCTGCCCGCGCCGCCGCGCGGGGGCTCCCCGCTGACCACCACGCAA
GGCGGCTCGCCCACCAAGCTGCAGCGCGGAGGCTCGGCCCCGGAGGGTGCCGCCTACGCCGCTC
CGCGGGGCTCCTCGCCCAAGCAGTCGCCCAGCCGCCTGGCCAAGTCCTACAGCACCAGCTCGCC
CATCAACATCGTCGTGTCCTCGGCCGGCCTGTCCCCGATCCGCGTGACCTCGCCCCCCACCGTG
CAGTCCACCATCTCCTCTTCGCCCATCCACCAGCTGAGCTCCACCATCGGCACCTACGCCACCC
TGTCGCCCACCAAGCGCCTGGTCCACGCGTCCGAACAGTACAGCAAGCATTCGCAGGAACTGTA
TGCCACCGCCACCCTCCAGAGGCCGGGCAGCCTGGCAGCTGGGTCCCGAGCCTCGTATAGCAGC
CAGCATGGGCACCTGGCCCCTGAGCTGCGGGCCCTGCAGTCCCCAGAGCACCACATAGACCCCA
TCTATGAAGACCGTGTCTATCAGAAGCCCCCTATGAGGAGTCTCAGCCAGAGCCAGGGGGATCC
TCTGCCGCCAGCACACACCGGCACCTTCCGCACGAGCACAGCCCCATCCTCCCCTGGTGTCGAC
TCCGTCCCCTTGCAGCGCACAGGCAGCCAACACGGGCCACAGAATGCCGCAGCAGCCACCTTCC
AGAGGGCCAGCTATGCTGCTGGCCCAGCCTCCAACTACGCAGACCCCTACAGACAGCTGCAGTA
TTGTGCCTCCGCTGACTCTCCGTACAGCAAATCTGGCCCTGCCCTCCCACCCGAAGGCACCTTG
GCCAGATCCCCGTCCATTGACAGCATTCAGAAAGACCCCAGGGAGTTCGGATGGAGAGACCCGG
AGCTACCTGAAGTGATACAGATGTTACAGCATCAGTTCCCTTCTGTCCAGTCCAACGCTGCAGC
TTACCTGCAACACCTCTGCTTCGGAGACAATAAGATCAAGGCAGAGATAAGGAGACAAGGTGGG
ATACAGCTCCTGGTGGACCTGCTGGATCACCGGATGACAGAAGTCCACCGTAGTGCCTGTGGGG
CTCTGAGGAACCTGGTATATGGAAAGGCCAATGATGATAACAAAATCGCCCTGAAAAACTGTGG
TGGTATCCCAGCACTGGTGAGACTCCTTCGCAAGACCACAGACCTGGAGATCCGGGAACTGGTC
ACAGGAGTCCTTTGGAACCTCTCATCATGCGATGCCCTCAAGATGCCAATCATCCAGGACGCCC
TGGCAGTGCTGACCAATGCAGTGATCATCCCTCACTCGGGCTGGGAGAATTCACCTCTTCAGGA
CGACCGGAAAATACAGCTGCATTCATCACAGGTGCTGCGCAACGCCACTGGGTGCCTAAGGAAT
GTAAGTTCAGCTGGAGAGGAGGCCCGCCGCAGAATGCGGGAGTGTGATGGGCTCACGGATGCCT
TGCTGTACGTGATTCAGTCTGCACTGGGGAGCAGTGAGATCGATAGCAAGACCGTTGAAAACTG
TGTGTGCATCTTGAGGAACCTCTCATACCGGCTAGCAGCAGAAACGTCTCAGGGACAGCACATG
GGCACAGACGAGCTGGACGGGCTGCTCTGCGGGGAGGCCAATGGCAAGGACGCAGAGAGTTCTG
GGTGCTGGGGCAAGAAGAAGAAGAAAAAGAAATCCCAGGATCAGTGGGATGGAGTAGGACCTCT
TCCAGACTGTGCAGAACCACCAAAAGGGATCCAGATGCTGTGGCACCCATCCATAGTCAAACCC
TACCTCACACTGCTCTCTGAGTGCTCAAACCCAGACACGCTGGAAGGGGCAGCGGGCGCCCTGC
AGAACTTGGCTGCAGGGAGCTGGAAGGGCTGGGCTGAGGATGTGGCAGGCATGGCGTATGCCCT
ACGTTCACTGCCAGAGGGGGCTCCCTGCCTGCCACAGTGGTCCGTGTATATCCGAGCTGCTGTC
CGGAAAGAGAAAGGCCTGCCCATTCTTGTGGAGCTCCTCCGAATAGACAATGACCGTGTAGTGT
GTGCAGTGGCCACGGCACTCCGGAACATGGCCCTGGATGTCAGAAACAAGGAACTCATTGGCAA
ATATGCAATGAGAGACCTGGTCCACCGGCTTCCTGGTGGGAACAACAGCAACAACACAGGGAGC
AAGGCCATGTCAGATGACACCGTGACAGCCGTGTGCTGTACCCTGCATGAAGTGATCACCAAGA
ACATGGAGAATGCCAAGGCCTTACGGGATGCTGGCGGCATTGAGAAGTTGGTCGGCATCTCCAA
AAGCAAAGGAGATAAGCACTCTCCAAAGGTGGTCAAGGCTGCTTCTCAGGTCCTAAACAGCATG
TGGCAGTATCGAGATCTGAGGAGTCTGTACAAGAAGGATGGATGGTCACAATATCACTTTGTAG
CCTCATCTTCAACCATCGAGAGGGATCGACAAAGGCCCTACTCCTCCTCCCGCACACCTTCCAT
CTCTCCTGTGCGTGTGTCTCCCAACAACCGATCAGCAAGTGCCCCAGCTTCACCTCGGGAAATG
ATCAGCCTCAAAGAAAGGAAGACGGACTATGAGTCCGCTGGCAACAGCGCCACTTACCATGGAA
CTAAAGGAGAGCACACCTCCAGAAAAGACACCATGACAGCTCAAAACACTGGAGTTTCAACTTT
GTATAGGAATTCATACGGTGCACCCGCTGAAGACATCAAGCAGAACCAGGTTTCCACACAGCCT
GTCCCCCAGGAACCAAGCAGGAAAGACTACGAGACCTACCAGCCCTTCCAGAATTCCACACGAA
ATTATGATGAGTCCTTCTTTGAGGACCAGGTTCATCACCGCCCTCCAGCGAGCGAGTACACCAT
GCACCTGGGCCTCAAGTCCACTGGCAACTATGTCGACTTCTACTCCGCTGCCCGTCCTTACAGT
GAACTGAACTATGAAACGAGCCACTACCCGGCCTCGCCCGACTCCTGGGTGTGAGGAGTCAGGA
CACGAGGCACTCTGGGGACAGTGCATGTGCATGCATACACCACAGGACATTCTGTTTCTTTTCT
TTTCTTTTCTCTCTTTTTTTTTCTTTCCCTGCAAATTTAGTTTGTTAAAGCCTGTTCCAAAAGG
AAGGCTGTGATAACCAGAAAGAAATACTCAGAGCTATTTTAGAAAGCTAAAATGAATCGAGCGT
TAACCAGGAAATCGATAGGAAGCTAAACGCAATCCTAATTGTGACCCTATTCAACACCTTTCTA
GTTTGAACCGTAGCGTTTTGAAAGTGCTTTATAGTGGGGCGGCTGAAGGAAGAAGAGAGGAGAC
AGTCAGGGTGGTGGGCGTGGAGGTTATCGCTGAGCACAAGGCGGAATAGTTTACACACTGTGGG
GGAACGGCTTCTCACGCTTTGTTTACTCTCTTCACCCATGTGACTCTAGGCTTCCAGTTGCATT
GGGGTTCCTCTGTACAGCAAGACGTCTCTTGCCTTTTGTTAATGCATTGTTGTAAAGTATTTGA
TGTACATTACAGATTAAAGACGAAGAGTGCATTGTGTATATTACACCAATGCCACTGTGTTTCC
TCATCAATGGTTCTAAATATTGCTCCAATCTCAAACTTTTGAAAGATGTATGGGTTTCCAGTTT
TCTTTTCTTTTCTTTCTCCCAGTATGTTTTAACAAAAAAGGAAAAAAAAACAGGAAAAAAAAGG
AATATTTAGCAGTATTGTTCGTTCTGATATGTGATTTGTTTGTGGCAACTAAACGCGGCATCCA
GCAGTTTCTCCCGAGCTGACACGTCATTCCACACCCCTCGTCAACAAAATGCTTTTTCACTGCC
TAAAATTTTAGATGTAGATATTTGAAATAGATTTTTTTTCATTTATACCAGTTTTCTTTATGAT
GATACAGTGTTAAAAGAAAATAAATTACAATTGATCTGTCATCCA

hide sequence

RefSeq Acc Id:

NM_001415019 ⟹ NP_001401948

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	82,879,469 - 83,727,409 (+)	NCBI
mRatBN7.2	2	81,168,525 - 82,016,495 (+)	NCBI

RefSeq Acc Id:

XM_039101550 ⟹ XP_038957478

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	83,040,595 - 83,727,409 (+)	NCBI
mRatBN7.2	2	81,329,687 - 82,016,495 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001258431	(Get FASTA)	NCBI Sequence Viewer
	NP_001401948	(Get FASTA)	NCBI Sequence Viewer
	XP_038957478	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAA23384	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000045121
	ENSRNOP00000096253
GenBank Protein	O35116	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001258431 ⟸ NM_001271502
- Peptide Label:	isoform 1
- UniProtKB:	F1M787 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPVPDQPPSASEKNSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVAS QLERCKLGSETGSMSSISSAGEQFHWQTQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDY STSERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGDTAPSQLPARSTQARAAGQSFSQGT TGRSGHLAGSEPAPPPPPPREPFAPSLGSAFHLPDAPPAAAALYYSSSTLPAPPRGGSPLTTTQ GGSPTKLQRGGSAPEGAAYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTV QSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSS QHGHLAPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTFRTSTAPSSPGVD SVPLQRTGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCASADSPYSKSGPALPPEGTL ARSPSIDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGG IQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELV TGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRN VSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHM GTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKP YLTLLSECSNPDTLEGAAGALQNLAAGSWKGWAEDVAGMAYALRSLPEGAPCLPQWSVYIRAAV RKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTGS KAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSM WQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREM ISLKERKTDYESAGNSATYHGTKGEHTSRKDTMTAQNTGVSTLYRNSYGAPAEDIKQNQVSTQP VPQEPSRKDYETYQPFQNSTRNYDESFFEDQVHHRPPASEYTMHLGLKSTGNYVDFYSAARPYS ELNYETSHYPASPDSWV hide sequence

Ensembl Acc Id:

ENSRNOP00000045121 ⟸ ENSRNOT00000044871

RefSeq Acc Id:	XP_038957478 ⟸ XM_039101550
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000096253 ⟸ ENSRNOT00000119467

RefSeq Acc Id:	NP_001401948 ⟸ NM_001415019
- Peptide Label:	isoform 2
- UniProtKB:	A0A8I6AP92 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O35116-F1-model_v2	AlphaFold	O35116	1-264	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620734	AgrOrtholog
BioCyc Gene	G2FUF-53883	BioCyc
Ensembl Genes	ENSRNOG00000010649	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000044871	ENTREZGENE
	ENSRNOT00000119467	ENTREZGENE
Gene3D-CATH	1.25.10.10	UniProtKB/Swiss-Prot
InterPro	ARM-like	UniProtKB/Swiss-Prot
	ARM-type_fold	UniProtKB/Swiss-Prot
	Armadillo	UniProtKB/Swiss-Prot
	Plakophilin/d_Catenin	UniProtKB/Swiss-Prot
NCBI Gene	114028	ENTREZGENE
PANTHER	CATENIN DELTA-2	UniProtKB/Swiss-Prot
	PTHR10372	UniProtKB/Swiss-Prot
Pfam	Arm	UniProtKB/Swiss-Prot
PhenoGen	Ctnnd2	PhenoGen
PROSITE	ARM_REPEAT	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000010649	RatGTEx
SMART	ARM	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot
UniProt	A0A8I6AP92	ENTREZGENE, UniProtKB/TrEMBL
	CTND2_RAT	UniProtKB/Swiss-Prot
	F1M787	ENTREZGENE, UniProtKB/TrEMBL
	O35116	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-25	Ctnnd2	catenin delta 2	Ctnnd2	catenin (cadherin-associated protein), delta 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-08-22	Ctnnd2	catenin (cadherin-associated protein), delta 2	Ctnnd2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-26	Ctnnd2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	Ctnnd2	catenin (cadherin-associated protein), delta 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Ctnnd2	catenin (cadherin-associated protein), delta 2		catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	Name updated	1299863	APPROVED
2002-08-07	Ctnnd2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

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Mammalian Phenotype