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Gene: Pcdhga4 (protocadherin gamma subfamily A, 4) Rattus norvegicus

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Symbol:

Pcdhga4

Name:

protocadherin gamma subfamily A, 4

RGD ID:

620725

Description:

Orthologous to human PCDHGA4 (protocadherin gamma subfamily A, 4); INTERACTS WITH paracetamol; trichloroethene; 1,2-dimethylhydrazine (ortholog).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Pcdhga3; protocadherin gamma subfamily A, 3; protocadherin gamma-A4; protocadherin gamma-A6

RGD Orthologs

Human

Mouse

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PCDHGA4 (protocadherin gamma subfamily A, 4)	RGD	RGD
Mus musculus (house mouse):	Pcdhga4 (protocadherin gamma subfamily A, 4)	RGD	RGD
Alliance orthologs ³
Homo sapiens (human):	PCDHGA4 (protocadherin gamma subfamily A, 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PCDHGA4 (protocadherin gamma subfamily A, 4)	Alliance	DIOPT (HGNC)
Mus musculus (house mouse):	Pcdhga4 (protocadherin gamma subfamily A, 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-233f7.1	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Cad96Cb	Alliance	DIOPT (InParanoid\|OMA)
Xenopus tropicalis (tropical clawed frog):	cenpv	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder)
Xenopus tropicalis (tropical clawed frog):	prodh	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	29,760,777 - 29,794,877 (+)	NCBI	GRCr8	GRCr8		GRCr8
mRatBN7.2	18	29,508,152 - 29,543,103 (+)	NCBI	mRatBN7.2	mRatBN7.2
Rnor_6.0	18	30,831,036 - 30,834,819 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	30,831,365 - 30,833,782 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	30,525,592 - 30,528,139 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	30,591,362 - 30,595,225 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	29,156,858 - 29,159,405 (+)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pcdhga4	Rat	genetic disease		ISO	RGD:156041659\|RGD:156042359\|RGD:156043126\|RGD:156043482\|RGD:156043811\|RGD:156046088\|RGD:156049117\|RGD:156050570\|RGD:156051878\|RGD:156052856\|RGD:156053332\|RGD:156054609\|RGD:156059438\|RGD:156061098\|RGD:156061584\|RGD:156063070\|RGD:156063471\|RGD:156064758\|RGD:156065436\|RGD:156068549\|RGD:156069693\|RGD:156071097\|RGD:156071163\|RGD:156071866\|RGD:156073874\|RGD:156074213\|RGD:156075413\|RGD:156075855\|RGD:156075921\|RGD:156075990\|RGD:156077240\|RGD:156079495\|RGD:156079762\|RGD:156081700\|RGD:156082603\|RGD:156082920\|RGD:156083027\|RGD:156083536\|RGD:156084829\|RGD:156088127\|RGD:156088421\|RGD:156089259\|RGD:156089365\|RGD:156089412\|RGD:156091385\|RGD:156094011\|RGD:156094026\|RGD:156094828\|RGD:156097201\|RGD:156100420\|RGD:156101274\|RGD:156102195\|RGD:156105980\|RGD:156112796\|RGD:156113394\|RGD:156113705\|RGD:156114002\|RGD:156114323\|RGD:156114507\|RGD:156114710\|RGD:156114766\|RGD:156115806\|RGD:156116380\|RGD:156118932\|RGD:156120274\|RGD:156120451\|RGD:156120702\|RGD:156122081\|RGD:156124679\|RGD:156125339\|RGD:156130191\|RGD:156132801\|RGD:156133050\|RGD:156133083\|RGD:156134204\|RGD:156134647\|RGD:156136978\|RGD:156137912\|RGD:156139822\|RGD:156140275\|RGD:156143829\|RGD:156145914\|RGD:156148281\|RGD:156149942\|RGD:156151284\|RGD:156152838\|RGD:156153249\|RGD:156153744\|RGD:156154472\|RGD:156155388\|RGD:156156813\|RGD:156157063\|RGD:156158722\|RGD:156159557\|RGD:156160078\|RGD:156160729\|RGD:156161252\|RGD:156161809\|RGD:156162011\|RGD:156163194\|RGD:156163334\|RGD:156164367\|RGD:156164757\|RGD:156165019\|RGD:156166500\|RGD:156168111\|RGD:156171011\|RGD:156172029\|RGD:156174115\|RGD:156175044\|RGD:156176992\|RGD:156177502\|RGD:156178027\|RGD:156179330\|RGD:156179831\|RGD:156180960\|RGD:156182632\|RGD:156184556\|RGD:156184861\|RGD:156185118\|RGD:156186379	9068941	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
Pcdhga4	Rat	genetic disease		ISO	RGD:401876631\|RGD:401877071\|RGD:401878241\|RGD:401879914\|RGD:401879948\|RGD:401880158\|RGD:401880241\|RGD:401880291\|RGD:401881397\|RGD:401882124\|RGD:401882235\|RGD:401882238\|RGD:401883527\|RGD:401883772\|RGD:401885504\|RGD:401885770\|RGD:401885855\|RGD:401886832\|RGD:401887269\|RGD:401888218\|RGD:401888290\|RGD:401890058\|RGD:401890314\|RGD:401890336\|RGD:401892742\|RGD:401892903\|RGD:401894649\|RGD:401895123\|RGD:401896950\|RGD:401897502\|RGD:401898017\|RGD:401898238\|RGD:401899081\|RGD:401899714	9068941	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
Pcdhga4	Rat	genetic disease		ISO	RGD:156352601\|RGD:156353264\|RGD:156357121\|RGD:156358217\|RGD:156358223\|RGD:156360006\|RGD:156361448\|RGD:156361670\|RGD:156364732\|RGD:156365104\|RGD:156368072\|RGD:156368629\|RGD:156369550\|RGD:156370366\|RGD:156374162\|RGD:156379304\|RGD:156380167\|RGD:156380821\|RGD:156382006\|RGD:156384823\|RGD:156384870\|RGD:156387842\|RGD:156388793\|RGD:156389353\|RGD:156389610\|RGD:156391763\|RGD:156395042\|RGD:156395361\|RGD:156395367\|RGD:156398030\|RGD:156399398\|RGD:329351575\|RGD:329352113\|RGD:329352227\|RGD:329353363\|RGD:329353399\|RGD:329353578\|RGD:329356298\|RGD:329357555\|RGD:329358224\|RGD:329358481\|RGD:329359489\|RGD:329359884\|RGD:329360103\|RGD:329360517\|RGD:329360626\|RGD:329361087\|RGD:329361697\|RGD:329361943\|RGD:329362542\|RGD:329364869\|RGD:329367113\|RGD:329367283\|RGD:329367552\|RGD:329367981\|RGD:329371664\|RGD:329373469\|RGD:329373881\|RGD:329373996\|RGD:329374030\|RGD:329374053\|RGD:329374540\|RGD:329375149\|RGD:329375324\|RGD:329375874\|RGD:329376275\|RGD:329376594\|RGD:329377146\|RGD:329377949\|RGD:329378010\|RGD:329378180\|RGD:329378661\|RGD:329379069\|RGD:329380099\|RGD:329380218\|RGD:329380331\|RGD:329380607\|RGD:329381237\|RGD:329381487\|RGD:329383728\|RGD:329385032\|RGD:329387147\|RGD:329387632\|RGD:329388541\|RGD:329388601\|RGD:329389063\|RGD:329389354\|RGD:329389692\|RGD:329390408\|RGD:329391139\|RGD:329391254\|RGD:329391518\|RGD:329393436\|RGD:329394211\|RGD:329394426\|RGD:329397148\|RGD:329397199\|RGD:329397714\|RGD:329397944\|RGD:329398033\|RGD:329398234\|RGD:329398537\|RGD:329398843\|RGD:329398870\|RGD:329399052\|RGD:329399353\|RGD:329399505\|RGD:329399507\|RGD:329400189\|RGD:329400636\|RGD:329401735\|RGD:329402407\|RGD:401719078\|RGD:401719883\|RGD:401720370\|RGD:401720610\|RGD:401720983\|RGD:401722216\|RGD:401723616\|RGD:401724521\|RGD:401725208	9068941	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
Pcdhga4	Rat	genetic disease		ISO	RGD:155902586\|RGD:155902788\|RGD:155903220\|RGD:155903805\|RGD:155904514\|RGD:155905273\|RGD:155905674\|RGD:155905813\|RGD:155905880\|RGD:155906131\|RGD:155906462\|RGD:155906929\|RGD:155907175\|RGD:155907329\|RGD:155907536\|RGD:155912023\|RGD:155912155\|RGD:155912557\|RGD:155912627\|RGD:155913561\|RGD:155913595\|RGD:155913603\|RGD:155914436\|RGD:155915452\|RGD:155915996\|RGD:155916043\|RGD:155916625\|RGD:155918551\|RGD:155919379\|RGD:155920281\|RGD:155920689\|RGD:155920697\|RGD:155921163\|RGD:155922839\|RGD:155923352\|RGD:155924727\|RGD:155924743\|RGD:155924753\|RGD:155929312\|RGD:155929916\|RGD:155930141\|RGD:155931317\|RGD:155931782\|RGD:155932583\|RGD:155933277\|RGD:155933817\|RGD:155933905\|RGD:155937922\|RGD:155938335\|RGD:155940290\|RGD:155941233\|RGD:155941628\|RGD:155944108\|RGD:155944220\|RGD:155944678\|RGD:155953194\|RGD:155953521\|RGD:155955468\|RGD:155956244\|RGD:155956824\|RGD:155957298\|RGD:155958863\|RGD:155959468\|RGD:155959489\|RGD:155959877\|RGD:155960257\|RGD:155961000\|RGD:155961125\|RGD:155962358\|RGD:155962480\|RGD:155964136\|RGD:155964981\|RGD:155966837\|RGD:155967238\|RGD:155968057\|RGD:155972017\|RGD:155972524\|RGD:155976050\|RGD:155977029\|RGD:155977068\|RGD:155979432\|RGD:155979444\|RGD:155981374\|RGD:155982322\|RGD:155982890\|RGD:155983047\|RGD:155986288\|RGD:155986554\|RGD:155987415\|RGD:155989655\|RGD:155992341\|RGD:155993388\|RGD:155995576\|RGD:155995634\|RGD:155996157\|RGD:155998185\|RGD:156002366\|RGD:156002452\|RGD:156004926\|RGD:156006203\|RGD:156013918\|RGD:156017533\|RGD:156017687\|RGD:156018352\|RGD:156018795\|RGD:156019979\|RGD:156020479\|RGD:156029915\|RGD:156030085\|RGD:156030434\|RGD:156032042\|RGD:156032265\|RGD:156032761\|RGD:156032899\|RGD:156036886\|RGD:156038036\|RGD:156038195\|RGD:156038439\|RGD:156038480\|RGD:156038579\|RGD:156039031	9068941	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
Pcdhga4	Rat	genetic disease		ISO	RGD:156188319\|RGD:156189043\|RGD:156191769\|RGD:156195296\|RGD:156196643\|RGD:156196811\|RGD:156196872\|RGD:156197736\|RGD:156198615\|RGD:156201282\|RGD:156201739\|RGD:156202992\|RGD:156207185\|RGD:156207553\|RGD:156207968\|RGD:156209854\|RGD:156213977\|RGD:156219160\|RGD:156222553\|RGD:156225166\|RGD:156227005\|RGD:156227201\|RGD:156227755\|RGD:156227878\|RGD:156228170\|RGD:156229410\|RGD:156229473\|RGD:156229492\|RGD:156229762\|RGD:156230343\|RGD:156233054\|RGD:156235508\|RGD:156236013\|RGD:156236159\|RGD:156237339\|RGD:156237449\|RGD:156238843\|RGD:156239505\|RGD:156240372\|RGD:156240500\|RGD:156243792\|RGD:156244232\|RGD:156244390\|RGD:156246021\|RGD:156246983\|RGD:156248219\|RGD:156250141\|RGD:156251291\|RGD:156251712\|RGD:156252253\|RGD:156253605\|RGD:156253618\|RGD:156254416\|RGD:156254962\|RGD:156255424\|RGD:156256547\|RGD:156256564\|RGD:156257028\|RGD:156257106\|RGD:156258193\|RGD:156258292\|RGD:156258525\|RGD:156259227\|RGD:156260062\|RGD:156260389\|RGD:156262066\|RGD:156263269\|RGD:156263859\|RGD:156265170\|RGD:156266381\|RGD:156268088\|RGD:156270347\|RGD:156274630\|RGD:156277396\|RGD:156278226\|RGD:156278402\|RGD:156283524\|RGD:156284499\|RGD:156285275\|RGD:156286054\|RGD:156286976\|RGD:156287591\|RGD:156289418\|RGD:156289594\|RGD:156292030\|RGD:156293828\|RGD:156295154\|RGD:156295170\|RGD:156295804\|RGD:156297006\|RGD:156297378\|RGD:156300898\|RGD:156302383\|RGD:156302396\|RGD:156304276\|RGD:156305908\|RGD:156307645\|RGD:156308246\|RGD:156315033\|RGD:156317131\|RGD:156321247\|RGD:156323700\|RGD:156325387\|RGD:156327707\|RGD:156329865\|RGD:156333161\|RGD:156335873\|RGD:156336347\|RGD:156336410\|RGD:156337779\|RGD:156338626\|RGD:156338855\|RGD:156338934\|RGD:156339134\|RGD:156339473\|RGD:156339486\|RGD:156340206\|RGD:156340627\|RGD:156345376\|RGD:156346309\|RGD:156351265	9068941	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
Pcdhga4	Rat	genetic disease		ISO	RGD:401726069\|RGD:401726280\|RGD:401727623\|RGD:401728174\|RGD:401728520\|RGD:401728584\|RGD:401729170\|RGD:401729619\|RGD:401731382\|RGD:401731568\|RGD:401731582\|RGD:401731593\|RGD:401732536\|RGD:401733626\|RGD:401733667\|RGD:401734054\|RGD:401735308\|RGD:401735369\|RGD:401736659\|RGD:401736665\|RGD:401736693\|RGD:401737098\|RGD:401737141\|RGD:401738932\|RGD:401739221\|RGD:401739484\|RGD:401740067\|RGD:401740486\|RGD:401741448\|RGD:401741732\|RGD:401742024\|RGD:401742395\|RGD:401742440\|RGD:401743537\|RGD:401744141\|RGD:401744775\|RGD:401746502\|RGD:401747318\|RGD:401747644\|RGD:401748281\|RGD:401749469\|RGD:401750022\|RGD:401751476\|RGD:401752013\|RGD:401752854\|RGD:401754091\|RGD:401754186\|RGD:401754293\|RGD:401755160\|RGD:401755391\|RGD:401757081\|RGD:401758968\|RGD:401760029\|RGD:401760323\|RGD:401760349\|RGD:401761799\|RGD:401762528\|RGD:401762554\|RGD:401763110\|RGD:401763593\|RGD:401764522\|RGD:401764806\|RGD:401765612\|RGD:401767369\|RGD:401767998\|RGD:401768001\|RGD:401768006\|RGD:401769718\|RGD:401770155\|RGD:401770157\|RGD:401770213\|RGD:401773598\|RGD:401774561\|RGD:401775030\|RGD:401775546\|RGD:401777592\|RGD:401778623\|RGD:401778711\|RGD:401779165\|RGD:401780228\|RGD:401780430\|RGD:401780459\|RGD:401780622\|RGD:401780657\|RGD:401781248\|RGD:401782694\|RGD:401782697\|RGD:401783486\|RGD:401784048\|RGD:401854376\|RGD:401855264\|RGD:401855393\|RGD:401858431\|RGD:401860282\|RGD:401860659\|RGD:401862652\|RGD:401862654\|RGD:401862948\|RGD:401863065\|RGD:401863076\|RGD:401863720\|RGD:401863721\|RGD:401863892\|RGD:401864198\|RGD:401865234\|RGD:401865684\|RGD:401865882\|RGD:401865970\|RGD:401868204\|RGD:401868699\|RGD:401869116\|RGD:401870668\|RGD:401870951\|RGD:401871523\|RGD:401872476\|RGD:401873160\|RGD:401873353\|RGD:401873501\|RGD:401874504\|RGD:401875708\|RGD:401876490	9068941	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
Pcdhga4	Rat	Hereditary Neoplastic Syndromes		ISO	(Homo sapiens)	9068941	ClinVar Annotator: match by term: Hereditary Cancer Syndrome	ClinVar	PMID:17963004\|PMID:18487285\|PMID:19279422\|PMID:19409520\|PMID:20685668\|PMID:21643010\|PMID:28492532

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pcdhga4	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Pcdhga4 (Mus musculus)	6480464	1,2-Dimethylhydrazine results in decreased expression of PCDHGA4 mRNA	CTD	PMID:22206623
Pcdhga4	Rat	2,2',5,5'-tetrachlorobiphenyl	decreases expression	ISO	PCDHGA4 (Homo sapiens)	6480464	2,5,2',5'-tetrachlorobiphenyl analog results in decreased expression of PCDHGA4 mRNA	CTD	PMID:36804509
Pcdhga4	Rat	4,4'-sulfonyldiphenol	affects methylation	ISO	Pcdhga4 (Mus musculus)	6480464	bisphenol S affects the methylation of PCDHGA4 gene	CTD	PMID:31683443
Pcdhga4	Rat	aflatoxin B1	decreases methylation	ISO	PCDHGA4 (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of PCDHGA4 gene	CTD	PMID:27153756
Pcdhga4	Rat	amosite asbestos	decreases methylation	ISO	PCDHGA4 (Homo sapiens)	6480464	Asbestos, Amosite results in decreased methylation of PCDHGA4 promoter	CTD	PMID:29626692
Pcdhga4	Rat	antirheumatic drug	increases expression	ISO	PCDHGA4 (Homo sapiens)	6480464	Antirheumatic Agents results in increased expression of PCDHGA4 mRNA	CTD	PMID:24449571
Pcdhga4	Rat	arsane	affects methylation	ISO	PCDHGA4 (Homo sapiens)	6480464	Arsenic affects the methylation of PCDHGA4 gene	CTD	PMID:25304211
Pcdhga4	Rat	arsenic atom	affects methylation	ISO	PCDHGA4 (Homo sapiens)	6480464	Arsenic affects the methylation of PCDHGA4 gene	CTD	PMID:25304211
Pcdhga4	Rat	benzo[a]pyrene	affects methylation	ISO	PCDHGA4 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of PCDHGA4 promoter	CTD	PMID:27901495
Pcdhga4	Rat	benzo[a]pyrene	increases methylation	ISO	Pcdhga4 (Mus musculus)	6480464	Benzo(a)pyrene results in increased methylation of PCDHGA4 exon	CTD	PMID:27901495
Pcdhga4	Rat	Butylbenzyl phthalate	increases expression	ISO	PCDHGA4 (Homo sapiens)	6480464	butylbenzyl phthalate results in increased expression of PCDHGA4 mRNA	CTD	PMID:22905168
Pcdhga4	Rat	cadmium dichloride	increases expression	ISO	PCDHGA4 (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of PCDHGA4 mRNA	CTD	PMID:38568856
Pcdhga4	Rat	CGP 52608	multiple interactions	ISO	PCDHGA4 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to PCDHGA4 gene]	CTD	PMID:28238834
Pcdhga4	Rat	crocidolite asbestos	decreases methylation	ISO	PCDHGA4 (Homo sapiens)	6480464	Asbestos, Crocidolite results in decreased methylation of PCDHGA4 promoter	CTD	PMID:29626692
Pcdhga4	Rat	doxorubicin	decreases expression	ISO	PCDHGA4 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of PCDHGA4 mRNA	CTD	PMID:29803840
Pcdhga4	Rat	ethanol	increases expression	ISO	Pcdhga4 (Mus musculus)	6480464	Ethanol results in increased expression of PCDHGA4 mRNA	CTD	PMID:30319688
Pcdhga4	Rat	ethanol	affects expression	ISO	Pcdhga4 (Mus musculus)	6480464	Ethanol affects the expression of PCDHGA4 mRNA	CTD	PMID:30319688
Pcdhga4	Rat	genistein	increases expression	ISO	Pcdhga4 (Mus musculus)	6480464	Genistein results in increased expression of PCDHGA4 mRNA	CTD	PMID:32186404
Pcdhga4	Rat	lipopolysaccharide	multiple interactions	ISO	PCDHGA4 (Homo sapiens)	6480464	S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in decreased expression of PCDHGA4 mRNA]	CTD	PMID:35811015
Pcdhga4	Rat	lipopolysaccharide	decreases expression	ISO	PCDHGA4 (Homo sapiens)	6480464	Lipopolysaccharides results in decreased expression of PCDHGA4 mRNA	CTD	PMID:35811015
Pcdhga4	Rat	nickel atom	decreases expression	ISO	PCDHGA4 (Homo sapiens)	6480464	Nickel results in decreased expression of PCDHGA4 mRNA	CTD	PMID:25583101
Pcdhga4	Rat	ozone	multiple interactions	ISO	Pcdhga4 (Mus musculus)	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ...	CTD	PMID:34911549
Pcdhga4	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of PCDHGA4 mRNA	CTD	PMID:33387578
Pcdhga4	Rat	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	ISO	PCDHGA4 (Homo sapiens)	6480464	S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in decreased expression of PCDHGA4 mRNA]	CTD	PMID:35811015
Pcdhga4	Rat	serpentine asbestos	decreases methylation	ISO	PCDHGA4 (Homo sapiens)	6480464	Asbestos, Serpentine results in decreased methylation of PCDHGA4 gene	CTD	PMID:29523930
Pcdhga4	Rat	sodium arsenite	decreases expression	ISO	Pcdhga4 (Mus musculus)	6480464	sodium arsenite results in decreased expression of PCDHGA4 mRNA	CTD	PMID:37682722
Pcdhga4	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of PCDHGA4 mRNA	CTD	PMID:33387578
Pcdhga4	Rat	valproic acid	increases methylation	ISO	PCDHGA4 (Homo sapiens)	6480464	Valproic Acid results in increased methylation of PCDHGA4 gene	CTD	PMID:29154799

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pcdhga4	Rat	spermatogenesis		IEP		68759		RGD

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pcdhga4	Rat	membrane	located_in	ISO	RGD:1623074,MGI:1935216	1624291	PMID:15347688	RGD	PMID:15347688

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

amosite asbestos (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

crocidolite asbestos (ISO)

doxorubicin (ISO)

ethanol (ISO)

genistein (ISO)

lipopolysaccharide (ISO)

nickel atom (ISO)

ozone (ISO)

paracetamol (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

serpentine asbestos (ISO)

sodium arsenite (ISO)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

spermatogenesis (IEP)

Cellular Component

membrane (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Multiple cadherin superfamily members with unique expression profiles are produced in rat testis.	Johnson KJ, etal., Endocrinology 2000 Feb;141(2):675-83.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:14672974	PMID:15347688	PMID:15744052

Genomics

Comparative Map Data

Pcdhga4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	29,760,777 - 29,794,877 (+)	NCBI	GRCr8	GRCr8		GRCr8
mRatBN7.2	18	29,508,152 - 29,543,103 (+)	NCBI	mRatBN7.2	mRatBN7.2
Rnor_6.0	18	30,831,036 - 30,834,819 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	30,831,365 - 30,833,782 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	30,525,592 - 30,528,139 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	30,591,362 - 30,595,225 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	29,156,858 - 29,159,405 (+)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

PCDHGA4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	141,355,021 - 141,512,975 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	141,355,021 - 141,512,975 (+)	Ensembl			hg38	GRCh38
GRCh37	5	140,734,588 - 140,892,542 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	140,714,952 - 140,872,730 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	140,714,951 - 140,717,480	NCBI
Celera	5	136,811,593 - 136,969,282 (+)	NCBI		Celera
Cytogenetic Map	5	q31.3	NCBI
HuRef	5	135,879,843 - 136,037,386 (+)	NCBI		HuRef
CHM1_1	5	140,167,975 - 140,325,823 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	141,880,645 - 142,038,959 (+)	NCBI		T2T-CHM13v2.0

Pcdhga4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	37,818,290 - 37,974,923 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	37,818,263 - 37,974,926 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	37,685,237 - 37,841,870 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	37,685,210 - 37,841,873 (+)	Ensembl			mm10	GRCm38
MGSCv37	18	37,845,054 - 38,001,524 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	37,811,248 - 37,967,847 (+)	NCBI		MGSCv36	mm8
Celera	18	39,018,458 - 39,185,349 (+)	NCBI		Celera
Cytogenetic Map	18	B3	NCBI
cM Map	18	19.55	NCBI

Variants

Variants in Pcdhga4
225 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	149
Count of miRNA genes:	122
Interacting mature miRNAs:	132
Transcripts:	ENSRNOT00000067185
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25071126	83910656	Rat
2301409	Cm70	Cardiac mass QTL 70		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	18	7065728	52065728	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	22015562	61600538	Rat
1331735	Rf44	Renal function QTL 44	2.981		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	18	15642280	31610627	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	12216684	31644508	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26822186	71822186	Rat
12904716	Am21	Aortic mass QTL 21		0.005	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	7065728	52065728	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	23494057	85487725	Rat
12904714	Cm131	Cardiac mass QTL 131		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	7065728	52065728	Rat
12904715	Cm132	Cardiac mass QTL 132		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	7065728	52065728	Rat
6903345	Bp349	Blood pressure QTL 349	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26822186	71822186	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	15226101	42690662	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26822186	71822186	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26822186	71822186	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5460455	42690191	Rat
6903349	Bp351	Blood pressure QTL 351	3.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
631509	Sald2	Serum aldosterone level QTL 2	2.9		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	18	26415821	71415821	Rat
6903351	Bp352	Blood pressure QTL 352	3.3		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26822186	71822186	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26822186	71822186	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26822186	71822186	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	12216684	31644508	Rat
1331775	Bp235	Blood pressure QTL 235	3.201		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	31610627	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	44930869	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19553532	85493247	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	12066482	57066482	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	3811902	30809809	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34566578	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4482648	49482648	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	54490981	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
11565454	Kidm59	Kidney mass QTL 59		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	7065728	52065728	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	86134022	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34566578	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	4307354	49307354	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	66	163	90	89	58	74	58	6	330	173	11	142	75	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001432426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008772071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF177693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000067185 ⟹ ENSRNOP00000059914

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	18	30,831,365 - 30,833,782 (+)	Ensembl

RefSeq Acc Id:

XM_008772071 ⟹ XP_008770293

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	29,760,777 - 29,769,040 (+)	NCBI
mRatBN7.2	18	29,508,152 - 29,515,363 (+)	NCBI
Rnor_6.0	18	30,831,036 - 30,834,819 (+)	NCBI

Sequence:

show sequence

TACAATGTACTCATATAAATAAAAATTAATTTTTAAAAAAAAGTGGGTTTAGCATGTGGTGGTT
TTTCAAAAATTTGTTGCAATAACAGTTTAGTACTCTGGGTGTCGCTGTTCACCACTCAGGGGTG
AAAATCAGGTATTTAGTAAGACCAAGATTTCCGGAGCATAAAGGACTGGTTATGGTCTTAAAGA
AAGCAGCAATCTGGACTCCTAGGAGCACCAAGGTCCAACAGTATAAGTACGTTATCTTGAAACC
CAAAGATTGAGGGGCTCATCAGGCCTGCACAGAAACAACGCCCAAGCTCAGGACTCTCTGCGGC
GAGACTGCAATGGCGGCTCCTTACGGATCATACCGCAGGGGACTAATCTGGATCTGCATTTACC
TTGGATCCCTATGCTACATCCGCGCGGAACAGATCCGGTACTCTGTGCCAGAAGAGCTGGAAAA
GGGCTCTGCTGTAGGTAATCTCGCCGCGGACCTGGGGTTGGAGCCTAAGAAACTGGGAGAACGC
GGAGTCCGCATCGTCTCCAGAGGTAAGACCCAGCTCTTTGCTCTGAATCCGCGAAGCGGCAGTT
TAGTGACTGCAGGGAGGATAGACAGGGAAGGGCTCTGTGACAGATCCCCAAAGTGTACCGCAAA
TCTGGAGATTCTCCTGGAGGATAAAGTGAGGATTCTAGCCGTAGAAGTGGAAATTATCGATGTT
AATGATAATGCCCCCAGTTTTGGAGCACAGCAGAGGGAAATAAAAGTTGCTGAAAGTGAAATTC
CTGGAACAAGATTTCCTCTTCCTGAAGCTTTTGATCCGGACATAGGGGTGAACGCCTTGCAGGG
TTACCAGCTCAGCTCCACTGGTCATTTCTCCCTGGATGTGCAAAATGGACCGGATGGGATTAAA
TACCCAGAACTGGTGCTAGAAAAAGCCTTAGACCGCGAGGAGGAAGCCTTTCATTACCTGGTTC
TCACCGCCTTCGACGGAGGCGACCCGGTTCGCTCTGGTACTGCCACAATTCAAATAACAGTCGT
GGACACCAATGACAATGCTCCTGTATTCACTCAGCCAGAGTACCACATTAGTGTGAAGGAGAAT
TTGCCTGTAGGCACCCGGCTACTTACCGTAAAAGCCAGTGACCCGGATGAAGGAGCCAATGGAG
AAGTGACATATTCTTTCCGGAATGTAAGAGACAAAATATCCCAGCTCTTCCAGCTGAATTCTCT
GACTGGGGACATCACAATGGTGGGGGAGCTGGATTATGAGGACTCTGGATTCTATGATGTTGAT
GTAGAAGCCCACGATGGACCTGGTCTTCGAGCTAGAAGTAAGGTACTGGTGACAGTTCTGGATG
TAAATGACAATGCTCCGGAGGTCACAGTCACCTCTCTCACCAGTTCTATCCAAGAAACTTCTCC
CCCAGGCACAGTGATTGCTCTCTTCAATGTGCACGACAGTGACTCGGGAGAGAATGGCCTTGTC
ACTTGTTCTATTCCGGATAATCTTCCATTCAGGCTGGAAAAGACCTATGGAAACTATCATCAGT
TGTTGATACACAGGACTCTGGACAGGGAAGAAGTCTCTGACTATAACATTACAATAACTGCCAC
CGACCAGGGAACTCCACCACTGTCTACAGAGACTTACATCTCATTGCAGGTGGTGGACATTAAT
GACAACCCGCCCACCTTCACCCATGCCTCCTATTCTGCCTACATTCCAGAAAACAACCCTAGAG
GAGCTGCCATCTTATCCATAACAGCCCAGGACCCAGACAGTGGTGAGAATGCCCAGGTAATCTA
CTCCCTGTCAGAGGACACCATCCAGGGGGCACCCCTGTCCTCCTACATCTCCATCAACTCCAAT
ACCGGTGTCCTTTATGCACTGCGTTCCTTTGATTATGAGCAGTTTCAAGACTTGAAGCTATTGG
TGACAGCCAGGGACAGTGGGAACCCTCCACTCAGCAGCAACGCGTCCCTGAGCTTGTTTGTGCT
GGACCAGAATGACAACACGCCTGAGATCCTGTACCCCACCGTCCCCACTGATGGTTCTACTGGC
GTGGAGCTGACCCCTCGTTCTGCAGAACCTGGATACCTGGTGACCAAGGTGGTGGCAGTAGACA
AAGACTCAGGACAGAATGCCTGGCTGTCCTACCGTCTGCTCAAAGCCAGCGAGCCAGGGCTCTT
CTCGGTGGGGCTGCACACAGGTGAGGTACGCACAGCTCGGGCCCTACTGGACCGAGATGCTCTG
AAGCAGAACCTGGTGGTGGCTGTGCAGGACCATGGCCAGCCCCCTCTCTCTGCCACAGTCACAC
TCACCATAGCCGTGTCAGACAACATCCCAGACATCCTGGCGGATTTGGGCAACATTAACCCTCA
CATTGACCAAGAGGATTCAGACATCACATTGTACCTGGTGGTAGCTGTGGCTGTGGTCTCTTGT
GTCTTCTTAGCCTTTGTCATTGTGCTGCTGATACACAGGCTCCGTCGCTGGCACTCAACCCGCC
TGCTTCAGGCTGCAGGTAACGGGTTGTCATCCATGCCGACATCGCATTTTGTGGGTGTGGATGG
CGTACATGCCTTCCTACAGACCTATTCTCATGAGGTCTCCCTCACAGCAGACTCTGGGAAGAGT
CACCTGATCTTCCCGCAGCCCAACTATGCAGATACGCTCATCAGCCAGGAGAGCTGTGCGAAAA
GTGACCCTCTCCTGGTATCGCAAGACTTGCTTGAAATAAAAGGAGATTCCAGTCTTCAGGTGAG
TGGCTCACCCTATAATGGATCTTACCTCACTAAAACACAGACACGATGGTTTGTAAAACACCTC
CAGTTGTATGTGTGTTGTATCAAAAATTTGCATTTCTTGATTAATAGTTCCTTGCTTTAAAAAG
AATAATGATTAATGATAGTCACTATACAAAGTTATTCCCTGATTAATAACCTTATTTTCTTTTT
TGTAATGATTGGAGTGGATTCCAGGCTGTGAGCATATTCGGCAAGGCTTCTTGTAATTGTACAA
TGAATTACACCTCAAAACCATGATTATTTTTTATTTAGCCTTCATATTTTTCATTTGGTAGTGA
TTTTGGTAAGAATTCCTTAATTTTAAACCATTCTCTTTTTAACTGTATATATTGGTGACATATA
CATTGATGACAGGCTAGAATTGACACGTGAATAGAAGGCAATTGCACAATTTTCCATTTCTATC
ACCTTTCTCATGGTGCTAATGGGGAATCTAGGCTGAATATTTTAAAACATTTTACTACAGTTTC
ACTTTCTCTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG
TATCTTGGAAGACAACCTTTGGGGAAACAGTTCTCTCTTTCCACTATGTGAATCCAAGAGATCA
AATTCAGGAGGACAGGTGTAGTGGCCAATAGTTTTGGCCACTGAGCCATTTTACCAGTCCTAAC
CTGATTTTTTTAAGTTCCCTTTATTACATTAGACTTTTCTTTGCTTGGAGTTTACTTCTCCTTC
CTTGAAAGGATTTTTTCCATTATAATAATGCAATGACAATTTATATGTAGTGAAAAATATTTAA
CCTCTAGCTATAACATTAACTTCTCTAGGAAATGGTATATTCCCAATAATTTTCTATGCAATGT
CTGACTGTCCAGTTTAGACTGGCCTTTAACTTAGTATGTAGCCTATCCAAGAGGGCCTGCAGTT
TGCAATTCTCTTTAAGTGCTAGAATTACAGGTGTGTGCCACTATGCCCAGCTCAAATAGTTTAT
CGTTGCT

hide sequence

RefSeq Acc Id:

XM_039097401 ⟹ XP_038953329

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	29,782,547 - 29,794,877 (+)	NCBI
mRatBN7.2	18	29,532,580 - 29,543,103 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001419355	(Get FASTA)	NCBI Sequence Viewer
	XP_008770293	(Get FASTA)	NCBI Sequence Viewer
	XP_038953329	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF87068	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_008770293 ⟸ XM_008772071
- Peptide Label:	isoform X1
- UniProtKB:	A6J388 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAPYGSYRRGLIWICIYLGSLCYIRAEQIRYSVPEELEKGSAVGNLAADLGLEPKKLGERGVR IVSRGKTQLFALNPRSGSLVTAGRIDREGLCDRSPKCTANLEILLEDKVRILAVEVEIIDVNDN APSFGAQQREIKVAESEIPGTRFPLPEAFDPDIGVNALQGYQLSSTGHFSLDVQNGPDGIKYPE LVLEKALDREEEAFHYLVLTAFDGGDPVRSGTATIQITVVDTNDNAPVFTQPEYHISVKENLPV GTRLLTVKASDPDEGANGEVTYSFRNVRDKISQLFQLNSLTGDITMVGELDYEDSGFYDVDVEA HDGPGLRARSKVLVTVLDVNDNAPEVTVTSLTSSIQETSPPGTVIALFNVHDSDSGENGLVTCS IPDNLPFRLEKTYGNYHQLLIHRTLDREEVSDYNITITATDQGTPPLSTETYISLQVVDINDNP PTFTHASYSAYIPENNPRGAAILSITAQDPDSGENAQVIYSLSEDTIQGAPLSSYISINSNTGV LYALRSFDYEQFQDLKLLVTARDSGNPPLSSNASLSLFVLDQNDNTPEILYPTVPTDGSTGVEL TPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQN LVVAVQDHGQPPLSATVTLTIAVSDNIPDILADLGNINPHIDQEDSDITLYLVVAVAVVSCVFL AFVIVLLIHRLRRWHSTRLLQAAGNGLSSMPTSHFVGVDGVHAFLQTYSHEVSLTADSGKSHLI FPQPNYADTLISQESCAKSDPLLVSQDLLEIKGDSSLQVSGSPYNGSYLTKTQTRWFVKHLQLY VCCIKNLHFLINSSLL hide sequence

Ensembl Acc Id:

ENSRNOP00000059914 ⟸ ENSRNOT00000067185

RefSeq Acc Id:	XP_038953329 ⟸ XM_039097401
- Peptide Label:	isoform X2

Protein Domains

Cadherin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LRA0-F1-model_v2	AlphaFold	F1LRA0	1-806	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620725	AgrOrtholog
BioCyc Gene	G2FUF-7808	BioCyc
Ensembl Genes	ENSRNOG00000042322	Ensembl
Gene3D-CATH	Cadherins	UniProtKB/TrEMBL
InterPro	Cadherin-like_dom	UniProtKB/TrEMBL
	Cadherin-like_sf	UniProtKB/TrEMBL
	Cadherin_C	UniProtKB/TrEMBL
	Cadherin_CBD	UniProtKB/TrEMBL
	Cadherin_CS	UniProtKB/TrEMBL
	Cadherin_N	UniProtKB/TrEMBL
	Protocadherin/Cadherin-CA	UniProtKB/TrEMBL
NCBI Gene	252894	ENTREZGENE
PANTHER	CADHERIN-87A	UniProtKB/TrEMBL
	PROTOCADHERIN GAMMA-A4	UniProtKB/TrEMBL
	PROTOCADHERIN GAMMA-A6	UniProtKB/TrEMBL
Pfam	Cadherin	UniProtKB/TrEMBL
	Cadherin_2	UniProtKB/TrEMBL
	Cadherin_C_2	UniProtKB/TrEMBL
	Cadherin_tail	UniProtKB/TrEMBL
PhenoGen	Pcdhga4	PhenoGen
PRINTS	CADHERIN	UniProtKB/TrEMBL
PROSITE	CADHERIN_1	UniProtKB/TrEMBL
	CADHERIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000042322	RatGTEx
SMART	SM00112	UniProtKB/TrEMBL
Superfamily-SCOP	Cadherin-like	UniProtKB/TrEMBL
UniProt	A6J388	ENTREZGENE, UniProtKB/TrEMBL
	A6J389	ENTREZGENE, UniProtKB/TrEMBL
	A6J395_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-12-05	Pcdhga4	protocadherin gamma subfamily A, 4	Pcdhga3	protocadherin gamma subfamily A, 3	Symbol and Name updated	1299863	APPROVED
2004-09-10	Pcdhga3	protocadherin gamma subfamily A, 3	Pcdhga4	protocadherin gamma subfamily A, 4	Symbol and Name updated	1299863	APPROVED
2002-08-07	Pcdhga4	protocadherin gamma subfamily A, 4			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in testis	68759

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar