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Gene: Elf1 (E74 like ETS transcription factor 1) Rattus norvegicus

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Symbol:

Elf1

Name:

E74 like ETS transcription factor 1

RGD ID:

620697

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human ELF1 (E74 like ETS transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

E74-like factor 1; E74-like factor 1 (ets domain transcription factor); ETS-related transcription factor Elf-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ELF1 (E74 like ETS transcription factor 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Elf1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Elf1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ELF1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ELF1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Elf1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ELF1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ELF1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Elf1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Elf1 (E74 like ETS transcription factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ELF1 (E74 like ETS transcription factor 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Elf1 (E74 like ETS transcription factor 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Eip74EF	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Eip74EF	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	elf-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	elf-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	elf1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	elf1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	elf1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	61,354,026 - 61,395,762 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	61,330,877 - 61,395,758 (+)	Ensembl				GRCr8
mRatBN7.2	15	54,890,644 - 54,986,721 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	54,865,616 - 54,986,699 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	59,078,340 - 59,119,021 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	60,196,734 - 60,237,414 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	57,021,604 - 57,062,278 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	61,772,544 - 61,868,442 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	61,826,711 - 61,868,343 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	65,436,987 - 65,532,178 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	60,793,794 - 60,835,189 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	54,525,607 - 54,566,099 (+)	NCBI		Celera
RGSC_v3.1	15	60,809,573 - 60,850,969 (+)	NCBI
Cytogenetic Map	15	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

cisplatin (ISO)

clofibrate (ISO)

clothianidin (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

DDE (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dichloromethane (ISO)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

epoxiconazole (ISO)

flavonoids (EXP)

FR900359 (ISO)

gentamycin (EXP)

geraniol (ISO)

GSK-J4 (ISO)

hydrogen peroxide (ISO)

ivermectin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

methotrexate (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (EXP)

N(4)-hydroxycytidine (ISO)

N-nitrosodiethylamine (ISO)

niclosamide (ISO)

oxaliplatin (EXP)

panobinostat (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

SB 431542 (ISO)

senecionine (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

testosterone enanthate (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

topotecan (EXP)

torcetrapib (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (IBA)

DNA-templated transcription (IEA)

negative regulation of T cell receptor signaling pathway (ISO)

positive regulation of DNA-templated transcription (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of cytokine production (ISO)

regulation of DNA-templated transcription (IEA,IMP)

regulation of transcription by RNA polymerase II (IBA,IEA)

Cellular Component

nucleoplasm (ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISO)

DNA-binding transcription factor activity (IEA,ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA,ISO)

sequence-specific DNA binding (IEA)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	Splice isoforms of transcription factor Elf-1 affecting its regulatory function in transcription-molecular cloning of rat Elf-1.	Nishiyama C, etal., Biosci Biotechnol Biochem 2000 Dec;64(12):2601-7.
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8756667	PMID:14738763	PMID:14970218	PMID:16002702	PMID:19674970	PMID:19796622

Genomics

Comparative Map Data

Elf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	61,354,026 - 61,395,762 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	61,330,877 - 61,395,758 (+)	Ensembl				GRCr8
mRatBN7.2	15	54,890,644 - 54,986,721 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	54,865,616 - 54,986,699 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	59,078,340 - 59,119,021 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	60,196,734 - 60,237,414 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	57,021,604 - 57,062,278 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	61,772,544 - 61,868,442 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	61,826,711 - 61,868,343 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	65,436,987 - 65,532,178 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	60,793,794 - 60,835,189 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	54,525,607 - 54,566,099 (+)	NCBI		Celera
RGSC_v3.1	15	60,809,573 - 60,850,969 (+)	NCBI
Cytogenetic Map	15	q12	NCBI

ELF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	40,931,919 - 41,061,386 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	40,931,242 - 41,061,440 (-)	Ensembl			hg38	GRCh38
GRCh37	13	41,506,055 - 41,635,522 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	40,404,164 - 40,454,418 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	13	40,404,164 - 40,454,418	NCBI
Celera	13	22,563,467 - 22,650,954 (-)	NCBI		Celera
Cytogenetic Map	13	q14.11	NCBI
HuRef	13	22,305,948 - 22,394,169 (-)	NCBI		HuRef
CHM1_1	13	41,473,692 - 41,561,371 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	40,150,930 - 40,280,534 (-)	NCBI		T2T-CHM13v2.0

Elf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	79,718,619 - 79,819,916 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	79,718,634 - 79,819,934 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	79,481,174 - 79,582,491 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	79,481,194 - 79,582,494 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	79,881,001 - 79,982,283 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	78,215,349 - 78,316,631 (+)	NCBI		MGSCv36	mm8
Celera	14	76,981,316 - 77,082,589 (+)	NCBI		Celera
Cytogenetic Map	14	D3	NCBI
cM Map	14	42.67	NCBI

Elf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955404	50,952,907 - 51,020,229 (-)	Ensembl
ChiLan1.0	NW_004955404	50,952,907 - 51,020,229 (-)	NCBI	ChiLan1.0	ChiLan1.0

ELF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	40,452,043 - 40,578,633 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	31,554,781 - 31,681,724 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	22,136,952 - 22,263,523 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	40,726,930 - 40,853,424 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	40,726,930 - 40,774,734 (-)	Ensembl			panPan2	panpan1.1

ELF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	9,565,912 - 9,671,017 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	9,592,978 - 9,670,271 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	9,562,008 - 9,668,069 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	9,789,000 - 9,895,485 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	9,789,000 - 9,894,739 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	9,487,393 - 9,593,262 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	9,536,952 - 9,642,910 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	9,551,384 - 9,657,678 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Elf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	151,345,939 - 151,450,022 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936667	500,195 - 553,808 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936667	449,682 - 553,780 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ELF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	25,772,316 - 25,900,802 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	11	25,772,090 - 25,896,613 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	26,327,352 - 26,385,612 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ELF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	19,218,161 - 19,303,116 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	19,217,771 - 19,303,113 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666057	24,903,520 - 25,019,136 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Elf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624748	14,017,621 - 14,091,619 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624748	13,987,001 - 14,090,451 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Elf1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	44,762,064 - 44,858,955 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Elf1
184 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	328
Count of miRNA genes:	187
Interacting mature miRNAs:	218
Transcripts:	ENSRNOT00000068269
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	44806773	104695021	Rat
1576315	Schws6	Schwannoma susceptibility QTL 6		0.0069	nervous system integrity trait (VT:0010566)	post-insult time of death (CMO:0002005)	15	60213984	105213984	Rat
152025253	Hrtrt24	Heart rate QTL 24	3.82		heart pumping trait (VT:2000009)		15	31855803	92671517	Rat
724545	Niddm54	Non-insulin dependent diabetes mellitus QTL 54		0.02	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	57203895	80107161	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	28527732	73527732	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	43677244	88677244	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	43677244	88677244	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	25285835	104695021	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	25285835	104695021	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	19155762	87086765	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	40463152	85463152	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	14926594	71614418	Rat
631550	Bw7	Body weight QTL 7	3.6		body mass (VT:0001259)	body weight (CMO:0000012)	15	22336351	67336351	Rat
2317050	Aia24	Adjuvant induced arthritis QTL 24	2.06		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	15	59257087	104257087	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	43677244	88677244	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	25285835	104695021	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	43677244	88677244	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	43677244	88677244	Rat

Markers in Region

D15Got206

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	54,953,233 - 54,953,351 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	61,834,982 - 61,835,099	NCBI	Rnor6.0
Rnor_5.0	15	65,498,411 - 65,498,528	UniSTS	Rnor5.0
RGSC_v3.4	15	60,802,070 - 60,802,187	UniSTS	RGSC3.4
Celera	15	54,533,883 - 54,534,000	UniSTS
Cytogenetic Map	15	q12	UniSTS

RH129784

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	54,984,733 - 54,984,918 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	61,866,473 - 61,866,657	NCBI	Rnor6.0
Rnor_5.0	15	65,530,209 - 65,530,393	UniSTS	Rnor5.0
RGSC_v3.4	15	60,834,313 - 60,834,497	UniSTS	RGSC3.4
Celera	15	54,565,223 - 54,565,407	UniSTS
RH 3.4 Map	15	460.5	UniSTS
Cytogenetic Map	15	q12	UniSTS

U19617

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	54,985,954 - 54,986,021 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	61,867,694 - 61,867,760	NCBI	Rnor6.0
Rnor_5.0	15	65,531,430 - 65,531,496	UniSTS	Rnor5.0
RGSC_v3.4	15	60,835,534 - 60,835,600	UniSTS	RGSC3.4
Celera	15	54,566,444 - 54,566,510	UniSTS
Cytogenetic Map	15	q12	UniSTS

RH138647

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	54,986,217 - 54,986,433 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	61,867,957 - 61,868,172	NCBI	Rnor6.0
Rnor_5.0	15	65,531,693 - 65,531,908	UniSTS	Rnor5.0
RGSC_v3.4	15	60,835,797 - 60,836,012	UniSTS	RGSC3.4
Celera	15	54,566,707 - 54,566,922	UniSTS
RH 3.4 Map	15	459.3	UniSTS
Cytogenetic Map	15	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB030216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB030217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB046531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC123280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB782606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000068269 ⟹ ENSRNOP00000060815

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	61,330,882 - 61,395,758 (+)	Ensembl
mRatBN7.2 Ensembl	15	54,865,616 - 54,986,699 (+)	Ensembl
Rnor_6.0 Ensembl	15	61,826,711 - 61,868,343 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079417 ⟹ ENSRNOP00000070086

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	61,330,897 - 61,395,758 (+)	Ensembl
mRatBN7.2 Ensembl	15	54,865,616 - 54,986,699 (+)	Ensembl
Rnor_6.0 Ensembl	15	61,826,937 - 61,866,924 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084005 ⟹ ENSRNOP00000072421

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	61,330,877 - 61,395,758 (+)	Ensembl
mRatBN7.2 Ensembl	15	54,865,616 - 54,986,699 (+)	Ensembl
Rnor_6.0 Ensembl	15	61,826,937 - 61,866,924 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000144030 ⟹ ENSRNOP00000106538

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	61,330,878 - 61,395,758 (+)	Ensembl

RefSeq Acc Id:

NM_053520 ⟹ NP_445972

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	61,354,026 - 61,394,669 (+)	NCBI
mRatBN7.2	15	54,944,958 - 54,985,610 (+)	NCBI
Rnor_6.0	15	61,826,706 - 61,867,349 (+)	NCBI
Rnor_5.0	15	65,436,987 - 65,532,178 (+)	NCBI
RGSC_v3.4	15	60,793,794 - 60,835,189 (+)	RGD
Celera	15	54,525,607 - 54,566,099 (+)	RGD

Sequence:

show sequence

TCAGGGACAAGAAGACCTAGTGAATGATTTCAGAAAAAGTGCCTGTTTGCTTAGGATGTCAGTG
CACCAAGCAAATCTGAAGCACTCCTTTCGCTGAGGAGCGTCCTGTCTGCAATAACTTCACAGAC
CTGCCCCAGAGGCTTTCCTCGAATTCCCTTGCGCCTTACCTACTGCTCCAGACTGGAAGCTGCT
TGGGACTTTTTCACGTGGATCTAAGGGGAATGCTTTACTATGGCTGCTGTTGTCCAACAGAACG
ACCTAGTGTTTGACTTTGCAAGCAACGTCATGGAGGATGAACAGCAGCTTGGCGACCCTGCCAT
ATTTCCTGCTGTCATTGTGGAACATGTTCCTGGTGCTGATATTCTCAATGGTTATGCCGGGCTA
GCCTGTGTGGAAGAACCCAATGACATGATTACTGAGAGCTCTCTGGATGTTGCTGAAGAAGAAA
TCATAGAGGATGACGATGACGACATCACCCTTACAGTCGAGGCCTCTTGTCACAATGGAGATGA
GACCATTGAGACCATTGGGGCTGCTGAGGCGCTCCTCAATATGGACTCTCCTGGCCCTGTACTG
GATGAAAAGCGAATCAATAATAATATATTTAGCTCTTCTGAAGATGACATCGTTGCCCCAATCA
CCCACGTGTCTGTCACACTGGATGGGATTCCTGAGGTGATGGAAACCCAGCAAGTGCAAGAGTC
CAATGCAGACTCCCCTGGAGCCTCCTCCCCAGAGCAGCCCAAGAGAAAGAAGGGAAGAAAAACA
AAACCACCACGACCAGATTCCCCGGCCACTACACCAAATATATCTGTGAAAAAGAAAAGTAAAG
ACGGGAAGGGAAACACAATTTACCTTTGGGAGTTTTTACTGGCTCTGCTTCAGGACAAAGCTAC
CTGTCCTAAGTACATCAAATGGACACAGCGAGAAAAAGGCATTTTTAAGTTGGTCGACTCTAAA
GCTGTGTCCAGATTATGGGGGAAGCACAAAAACAAACCTGACATGAACTATGAGACCATGGGGC
GAGCACTCAGGTACTATTACCAAAGAGGTATTCTTGCAAAAGTGGAAGGTCAGCGCTTGGTGTA
TCAGTTTAAAGAAATGCCAAAAGACCTTATCTACATAGACGATGAGGGTCCAAGTTCCAGCACA
GAGTCTTCAGATCAGTCCTTATCTTCAACGACCACTTCTAGTCGGAATCAAGCAAACCGAACAA
GAATGTCTTCAAGTCCAGGAATAAAAGGAGGGGCCACTACAATTCTAAAACCAGGGAATCCTAA
AGTTGCAAAACCCAAAGACACCGTGGAAGTTGGGCAGCCTTCAGAAGTTTTGAGGACAGTGCAG
CCCTCACAGGCTCCCTATCCTACCCAGCTCTTCCGGACTGTCCATGTGGTACAGCCAGTACAAG
CCATCCCCGAAGAAGCAACCATAACCAGCACCATGCAGGAGGAAGCTGCAGGTTCTTCAGTTCA
GGGCATTAGGACGATACAGGCTTCAACCCAGGTTCCAGTAGTCGTGTCTCCTGGCAACCAACAG
CTACATACAGTAACACTCCAGACAGTGCCACTCACAACGGTTATAGCCAGCACAGACCCGTCAT
CAGGTGCAGGGCCGCAGAAATTTATTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACT
GAAAGAAAACGTCCTGCTACAGTCACAGAAGCCGGGCTCTCCTCCTTCAATCGTCTTCAGCCCT
ACCCCAGTACAGCAGGTCCTTACGGGCAGCGTTCAGTCCCTTGGCAATGGAGCTGTCAGTATGG
CTTCACCTCCAAACTTCAGTGCTACCGCACCTGTGGTGACTTTCTCTCGGAGCTCACAGCTGGC
TGCACACCCACCAGGCACCGTGATCACGTCTGTTATCAAAGCTCAGGAAACAAAAACTCCTAAA
GCAGAGGTGGAGAAAAAGGCTGAAGGTCATTTGAATGGAGACCCTGAGGAAATTGAACAGCAGC
CCCAGCCTTATGTGATGGTGGTGTCCAGTTCAAATGGGTTTTCCTCTCAGGTAGCCATCACACA
GAATGAACTGCTAGAGCCCAGCTCTTTTTAATTACTACACCAAAGGAATTATGGGTGGTTATTT
TTTTTAATTGAACTCATTTTTGGTTGTCTGACCATAACATGATTTTTTTCTAAGATAAATCCAC
AGAAGATCTTAATTTTGTAATTGTTAAAAACAGTGACCTTTGCCTTTGCTAGATAAGGAGGAAA
ACCCATGTATGTCTCCTCTCTAAATGTTTCAGAACTGAGTTGTGAAGGAGCAGGAATTTTATAC
GATGAAGAAATTCTTGAAATTTTTTTCAGTTGCTATATCATAAGTATTTTTAAAGTTTCTTTTC
TAGCTTGACACTGTATTAGCTTCCTGAATTGTTCGAAAATACTACTTAAATATACGTCAAGAGG
AAATTTATATAGGAAACATTTTCATTCCACTTGTATAATTTAAGTCTTGACTCTTTTCAGATGC
AAGAAACT

hide sequence

RefSeq Acc Id:

XM_039093704 ⟹ XP_038949632

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	61,354,187 - 61,395,762 (+)	NCBI
mRatBN7.2	15	54,920,691 - 54,986,721 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_445972	(Get FASTA)	NCBI Sequence Viewer
	XP_038949632	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAB20034	(Get FASTA)	NCBI Sequence Viewer
	BAB20035	(Get FASTA)	NCBI Sequence Viewer
	BAB62174	(Get FASTA)	NCBI Sequence Viewer
	EDM02359	(Get FASTA)	NCBI Sequence Viewer
	EDM02360	(Get FASTA)	NCBI Sequence Viewer
	EDM02361	(Get FASTA)	NCBI Sequence Viewer
	EDM02362	(Get FASTA)	NCBI Sequence Viewer
	EDM02363	(Get FASTA)	NCBI Sequence Viewer
	EDM02364	(Get FASTA)	NCBI Sequence Viewer
	EDM02365	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000060815
	ENSRNOP00000060815.2
	ENSRNOP00000070086.1
	ENSRNOP00000072421.2
	ENSRNOP00000106538
	ENSRNOP00000106538.1

RefSeq Acc Id:

NP_445972 ⟸ NM_053520

- UniProtKB:

G3V9V2 (UniProtKB/TrEMBL), Q9EQY3 (UniProtKB/TrEMBL), A6HTZ6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAVVQQNDLVFDFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNGYAGLACVEEPNDMITES
SLDVAEEEIIEDDDDDITLTVEASCHNGDETIETIGAAEALLNMDSPGPVLDEKRINNNIFSSS
EDDIVAPITHVSVTLDGIPEVMETQQVQESNADSPGASSPEQPKRKKGRKTKPPRPDSPATTPN
ISVKKKSKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKP
DMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEGPSSSTESSDQSLSSTTTS
SRNQANRTRMSSSPGIKGGATTILKPGNPKVAKPKDTVEVGQPSEVLRTVQPSQAPYPTQLFRT
VHVVQPVQAIPEEATITSTMQEEAAGSSVQGIRTIQASTQVPVVVSPGNQQLHTVTLQTVPLTT
VIASTDPSSGAGPQKFILQAIPSSQPMTVLKENVLLQSQKPGSPPSIVFSPTPVQQVLTGSVQS
LGNGAVSMASPPNFSATAPVVTFSRSSQLAAHPPGTVITSVIKAQETKTPKAEVEKKAEGHLNG
DPEEIEQQPQPYVMVVSSSNGFSSQVAITQNELLEPSSF

hide sequence

Ensembl Acc Id:

ENSRNOP00000070086 ⟸ ENSRNOT00000079417

Ensembl Acc Id:

ENSRNOP00000060815 ⟸ ENSRNOT00000068269

Ensembl Acc Id:

ENSRNOP00000072421 ⟸ ENSRNOT00000084005

RefSeq Acc Id:	XP_038949632 ⟸ XM_039093704
- Peptide Label:	isoform X1
- UniProtKB:	Q9EQY2 (UniProtKB/TrEMBL), A6HTZ9 (UniProtKB/TrEMBL), Q9EQY3 (UniProtKB/TrEMBL), A6HTZ8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000106538 ⟸ ENSRNOT00000144030

Protein Domains

ETS Transcription factor Elf N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V9V2-F1-model_v2	AlphaFold	G3V9V2	1-615	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620697	AgrOrtholog
BioCyc Gene	G2FUF-12990	BioCyc
Ensembl Genes	ENSRNOG00000011762	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000068269	ENTREZGENE
	ENSRNOT00000068269.4	UniProtKB/TrEMBL
	ENSRNOT00000079417.3	UniProtKB/TrEMBL
	ENSRNOT00000084005.3	UniProtKB/TrEMBL
	ENSRNOT00000144030	ENTREZGENE
	ENSRNOT00000144030.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
InterPro	Ets	UniProtKB/TrEMBL
	ETS_fam	UniProtKB/TrEMBL
	TF_Elf-1_N	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	rno:85424	UniProtKB/TrEMBL
NCBI Gene	85424	ENTREZGENE
PANTHER	ETS-RELATED TRANSCRIPTION FACTOR ELF-1	UniProtKB/TrEMBL
	PTHR11849	UniProtKB/TrEMBL
Pfam	Elf-1_N	UniProtKB/TrEMBL
	Ets	UniProtKB/TrEMBL
PhenoGen	Elf1	PhenoGen
PRINTS	ETSDOMAIN	UniProtKB/TrEMBL
PROSITE	ETS_DOMAIN_1	UniProtKB/TrEMBL
	ETS_DOMAIN_2	UniProtKB/TrEMBL
	ETS_DOMAIN_3	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000011762	RatGTEx
SMART	ETS	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
UniProt	A0ABZ3NN45_RAT	UniProtKB/TrEMBL
	A6HTZ6	ENTREZGENE, UniProtKB/TrEMBL
	A6HTZ8	ENTREZGENE, UniProtKB/TrEMBL
	A6HTZ9	ENTREZGENE, UniProtKB/TrEMBL
	A6HU00_RAT	UniProtKB/TrEMBL
	A6HU01_RAT	UniProtKB/TrEMBL
	A6HU02_RAT	UniProtKB/TrEMBL
	G3V9V2	ENTREZGENE, UniProtKB/TrEMBL
	Q9EQY2	ENTREZGENE
	Q9EQY3	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	Q9EQY1	UniProtKB/TrEMBL
	Q9EQY2	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-03-07	Elf1	E74 like ETS transcription factor 1	Elf1	E74-like factor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Elf1	E74-like factor 1		E74-like factor 1 (ets domain transcription factor)	Name updated	1299863	APPROVED
2002-08-07	Elf1	E74-like factor 1 (ets domain transcription factor)			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_mutations_overexpression	overexpression inhibited Fc epsilonRI alpha chain expression	632590

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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