Clic5 (chloride intracellular channel 5) - Rat Genome Database

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Gene: Clic5 (chloride intracellular channel 5) Rattus norvegicus
Analyze
Symbol: Clic5
Name: chloride intracellular channel 5
RGD ID: 620659
Description: Enables chloride channel activity. Predicted to be involved in chloride transport and sensory perception of sound. Predicted to act upstream of or within several processes, including auditory receptor cell stereocilium organization; diet induced thermogenesis; and neuromuscular process controlling balance. Located in stereocilium bundle. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 103. Orthologous to human CLIC5 (chloride intracellular channel 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chloride intracellular channel protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,208,455 - 24,310,964 (-)NCBIGRCr8
mRatBN7.2916,710,980 - 16,813,502 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl916,710,980 - 16,813,427 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,300,548 - 25,400,082 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,374,783 - 30,474,345 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0928,663,965 - 28,763,534 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,121,676 - 19,372,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,121,677 - 19,372,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,203,018 - 18,251,818 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0918,004,699 - 18,049,825 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4912,370,341 - 12,472,969 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1912,367,663 - 12,470,290 (-)NCBI
Celera914,441,285 - 14,540,691 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
carbon nanotube  (ISO)
carnosic acid  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
crocidolite asbestos  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
furan  (EXP)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
inulin  (ISO)
isoprenaline  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentane-2,3-dione  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenethyl caffeate  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function. Gagnon LH, etal., J Neurosci. 2006 Oct 4;26(40):10188-98.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI. Salles FT, etal., Cytoskeleton (Hoboken). 2014 Jan;71(1):61-78. doi: 10.1002/cm.21159. Epub 2013 Dec 10.
9. Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease. Steinmeyer K, etal., J Biol Chem 1995 Dec 29;270(52):31172-7.
Additional References at PubMed
PMID:10793131   PMID:12163479   PMID:19056867   PMID:20357015   PMID:20664558   PMID:22871113   PMID:24781754   PMID:26777142  


Genomics

Comparative Map Data
Clic5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,208,455 - 24,310,964 (-)NCBIGRCr8
mRatBN7.2916,710,980 - 16,813,502 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl916,710,980 - 16,813,427 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,300,548 - 25,400,082 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,374,783 - 30,474,345 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0928,663,965 - 28,763,534 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,121,676 - 19,372,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,121,677 - 19,372,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,203,018 - 18,251,818 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0918,004,699 - 18,049,825 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4912,370,341 - 12,472,969 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1912,367,663 - 12,470,290 (-)NCBI
Celera914,441,285 - 14,540,691 (-)NCBICelera
Cytogenetic Map9q13NCBI
CLIC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38645,880,827 - 46,129,819 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl645,880,827 - 46,080,348 (-)EnsemblGRCh38hg38GRCh38
GRCh37645,866,188 - 46,097,556 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36645,974,171 - 46,091,553 (-)NCBINCBI36Build 36hg18NCBI36
Build 34645,977,485 - 46,091,545NCBI
Celera647,419,073 - 47,600,603 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef645,589,507 - 45,771,107 (-)NCBIHuRef
CHM1_1645,869,674 - 46,051,333 (-)NCBICHM1_1
T2T-CHM13v2.0645,716,118 - 45,964,907 (-)NCBIT2T-CHM13v2.0
Clic5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391744,445,671 - 44,591,059 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1744,445,659 - 44,591,059 (+)EnsemblGRCm39 Ensembl
GRCm381744,134,762 - 44,280,169 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1744,188,584 - 44,280,172 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1744,134,768 - 44,280,172 (+)EnsemblGRCm38mm10GRCm38
MGSCv371744,325,521 - 44,417,117 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361743,651,627 - 43,743,223 (+)NCBIMGSCv36mm8
Celera1747,604,897 - 47,706,768 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1720.53NCBI
Clic5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,053,885 - 11,118,255 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,053,885 - 11,118,150 (-)NCBIChiLan1.0ChiLan1.0
CLIC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2560,387,381 - 60,505,130 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1656,253,426 - 56,371,209 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0645,474,797 - 45,592,407 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1646,753,007 - 46,934,100 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl646,753,013 - 46,934,100 (-)Ensemblpanpan1.1panPan2
CLIC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,160,524 - 14,318,174 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,144,390 - 14,318,582 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,193,104 - 14,350,325 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01214,660,621 - 14,818,027 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1214,644,744 - 14,818,385 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,177,139 - 14,334,394 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,265,255 - 14,422,839 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01214,361,798 - 14,519,297 (-)NCBIUU_Cfam_GSD_1.0
Clic5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494649,578,625 - 49,741,329 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647614,283,006 - 14,381,634 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647614,234,447 - 14,381,582 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLIC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl740,682,907 - 40,863,886 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1740,683,044 - 40,808,017 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2746,946,099 - 47,128,142 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CLIC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11726,231,192 - 26,364,076 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1726,231,728 - 26,343,346 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604445,867,551 - 46,089,886 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clic5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475414,370,425 - 14,434,269 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475414,335,173 - 14,433,721 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Clic5
963 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:612
Count of miRNA genes:265
Interacting mature miRNAs:335
Transcripts:ENSRNOT00000073667
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat

Markers in Region
D9Got213  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2916,808,480 - 16,808,679 (+)MAPPERmRatBN7.2
Rnor_6.0919,367,803 - 19,368,001NCBIRnor6.0
Rnor_5.0918,246,948 - 18,247,146UniSTSRnor5.0
RGSC_v3.4912,468,011 - 12,468,209UniSTSRGSC3.4
Celera914,535,914 - 14,536,112UniSTS
Cytogenetic Map9q12UniSTS
D9Got215  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2916,789,281 - 16,789,545 (+)MAPPERmRatBN7.2
Rnor_6.0919,348,552 - 19,348,815NCBIRnor6.0
Rnor_5.0918,227,697 - 18,227,960UniSTSRnor5.0
RGSC_v3.4912,448,811 - 12,449,074UniSTSRGSC3.4
Celera914,516,711 - 14,516,975UniSTS
Cytogenetic Map9q12UniSTS
AU046523  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2916,756,986 - 16,757,082 (+)MAPPERmRatBN7.2
Rnor_6.0919,167,595 - 19,167,690NCBIRnor6.0
Rnor_5.0918,050,402 - 18,050,497UniSTSRnor5.0
RGSC_v3.4912,416,519 - 12,416,614UniSTSRGSC3.4
Celera914,487,249 - 14,487,344UniSTS
Cytogenetic Map9q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 32 3 13 8 11 1 29 4 11 8
Low 1 11 54 41 6 41 53 6 35
Below cutoff 20 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000073667   ⟹   ENSRNOP00000067890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl919,121,677 - 19,372,673 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079517   ⟹   ENSRNOP00000072035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl916,710,980 - 16,813,427 (-)Ensembl
Rnor_6.0 Ensembl919,123,498 - 19,372,673 (-)Ensembl
RefSeq Acc Id: NM_053603   ⟹   NP_446055
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,208,455 - 24,310,964 (-)NCBI
mRatBN7.2916,710,980 - 16,813,502 (-)NCBI
Rnor_6.0919,121,676 - 19,372,673 (-)NCBI
Rnor_5.0918,004,699 - 18,049,825 (-)NCBI
Rnor_5.0918,203,018 - 18,251,818 (-)NCBI
RGSC_v3.4912,370,341 - 12,472,969 (-)RGD
Celera914,441,285 - 14,540,691 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446055 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG49367 (Get FASTA)   NCBI Sequence Viewer  
  EDM18716 (Get FASTA)   NCBI Sequence Viewer  
  EDM18717 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072035
  ENSRNOP00000072035.1
  ENSRNOP00055010401
  ENSRNOP00060029589
  ENSRNOP00065032662
GenBank Protein Q9EPT8 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_446055   ⟸   NM_053603
- UniProtKB: Q9EPT8 (UniProtKB/Swiss-Prot),   A6JJ16 (UniProtKB/TrEMBL),   A6JJ15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072035   ⟸   ENSRNOT00000079517
RefSeq Acc Id: ENSRNOP00000067890   ⟸   ENSRNOT00000073667
Protein Domains
GST C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EPT8-F1-model_v2 AlphaFold Q9EPT8 1-251 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696550
Promoter ID:EPDNEW_R7073
Type:initiation region
Name:Clic5_1
Description:chloride intracellular channel 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0919,372,745 - 19,372,805EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620659 AgrOrtholog
BioCyc Gene G2FUF-28135 BioCyc
Ensembl Genes ENSRNOG00000047218 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055007775 UniProtKB/Swiss-Prot
  ENSRNOG00060020769 UniProtKB/Swiss-Prot
  ENSRNOG00065023491 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000079517 ENTREZGENE
  ENSRNOT00000079517.2 UniProtKB/Swiss-Prot
  ENSRNOT00055013019 UniProtKB/Swiss-Prot
  ENSRNOT00060035958 UniProtKB/Swiss-Prot
  ENSRNOT00065040158 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1050.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CLIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CLIC5_C_GST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94272 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 94272 ENTREZGENE
PANTHER CHLORIDE INTRACELLULAR CHANNEL PROTEIN 5 UniProtKB/TrEMBL
  CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45476:SF4 UniProtKB/Swiss-Prot
Pfam GST_C_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Clic5 PhenoGen
PRINTS INTCLCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GST_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047218 RatGTEx
  ENSRNOG00055007775 RatGTEx
  ENSRNOG00060020769 RatGTEx
  ENSRNOG00065023491 RatGTEx
Superfamily-SCOP GST C-terminal domain-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6JJ15 ENTREZGENE, UniProtKB/TrEMBL
  A6JJ16 ENTREZGENE, UniProtKB/TrEMBL
  CLIC5_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Clic5  chloride intracellular channel 5      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Clic5  chloride intracellular channel 5      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_disease mutation of the human homolog may cause Dent's disease, X-linked hereditary nephrolithiasis 1302221