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Gene: Tas1r3 (taste 1 receptor member 3) Rattus norvegicus

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Symbol:

Tas1r3

Name:

taste 1 receptor member 3

RGD ID:

620539

Description:

Enables taste receptor activity. Involved in sensory perception of sweet taste and sensory perception of umami taste. Predicted to be located in membrane. Predicted to be part of sweet taste receptor complex. Predicted to be active in plasma membrane. Orthologous to human TAS1R3 (taste 1 receptor member 3); INTERACTS WITH ammonium chloride; bisphenol A; diclofenac.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

sweet taste receptor T1R3; T1r3; taste receptor type 1 member 3; taste receptor, type 1, member 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TAS1R3 (taste 1 receptor member 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tas1r3 (taste receptor, type 1, member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tas1r3 (taste 1 receptor member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TAS1R3 (taste 1 receptor member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TAS1R3 (taste 1 receptor member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tas1r3 (taste 1 receptor member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TAS1R3 (taste 1 receptor member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TAS1R3 (taste 1 receptor member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tas1r3 (taste 1 receptor member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tas1r3 (taste 1 receptor member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tas1r3 (taste receptor, type 1, member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TAS1R3 (taste 1 receptor member 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tas1r3 (taste receptor, type 1, member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,750,937 - 171,754,993 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	171,750,937 - 171,754,993 (-)	Ensembl				GRCr8
mRatBN7.2	5	166,468,703 - 166,472,759 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,469,589 - 166,472,742 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	169,174,257 - 169,177,410 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	170,995,678 - 170,998,831 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,958,209 - 170,961,362 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	173,307,325 - 173,312,950 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	173,308,870 - 173,312,023 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	176,784,486 - 176,787,639 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	172,718,551 - 172,721,704 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	164,670,308 - 164,673,461 (-)	NCBI		Celera
RGSC_v3.1	5	172,729,045 - 172,732,199 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

male infertility (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

aldehydo-D-glucose (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

aspartame (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cisplatin (ISO)

D-glucose (ISO)

dextran sulfate (ISO)

diclofenac (EXP)

dioxygen (ISO)

endosulfan (EXP)

furan (EXP)

glucose (ISO)

graphite (EXP)

iron(2+) sulfate (anhydrous) (ISO)

letrozole (EXP)

monosodium L-glutamate (ISO)

neohesperidin dihydrochalcone (ISO)

neotame (ISO)

okadaic acid (ISO)

ozone (ISO)

PCB138 (ISO)

pirinixic acid (ISO)

resveratrol (ISO)

saccharin (EXP,ISO)

silicon dioxide (ISO)

sucralose (ISO)

sucrose (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

zinc sulfate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of sweet taste (IEA,ISO,TAS)

detection of chemical stimulus involved in sensory perception of taste (IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of sweet taste (IBA,IDA,IEA,ISO)

sensory perception of taste (IEA)

sensory perception of umami taste (IBA,IDA,IEA,ISO)

signal transduction (IEA)

Cellular Component

membrane (IC,IEA)

plasma membrane (IBA,IEA,ISO)

sweet taste receptor complex (IEA,ISO)

Molecular Function

G protein-coupled receptor activity (IBA,IEA)

protein binding (ISO)

sweet taste receptor activity (IBA,IEA,ISO)

taste receptor activity (IDA,IEA,IPI,ISO)

transmembrane signaling receptor activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Human receptors for sweet and umami taste.	Li X, etal., Proc Natl Acad Sci U S A 2002 Apr 2;99(7):4692-6.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	Mammalian sweet taste receptors.	Nelson G, etal., Cell 2001 Aug 10;106(3):381-90.
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12892531	PMID:15299024	PMID:16720576	PMID:20156422	PMID:20943918	PMID:24898279	PMID:26096555	PMID:28474538	PMID:28782537	PMID:31655082

Genomics

Comparative Map Data

Tas1r3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,750,937 - 171,754,993 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	171,750,937 - 171,754,993 (-)	Ensembl				GRCr8
mRatBN7.2	5	166,468,703 - 166,472,759 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,469,589 - 166,472,742 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	169,174,257 - 169,177,410 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	170,995,678 - 170,998,831 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,958,209 - 170,961,362 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	173,307,325 - 173,312,950 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	173,308,870 - 173,312,023 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	176,784,486 - 176,787,639 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	172,718,551 - 172,721,704 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	164,670,308 - 164,673,461 (-)	NCBI		Celera
RGSC_v3.1	5	172,729,045 - 172,732,199 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

TAS1R3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	1,331,280 - 1,335,314 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	1,331,280 - 1,335,314 (+)	Ensembl			hg38	GRCh38
GRCh37	1	1,266,660 - 1,270,694 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	1,256,589 - 1,259,707 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	1,311,298 - 1,314,416 (-)	NCBI		Celera
Cytogenetic Map	1	p36.33	NCBI
HuRef	1	537,931 - 541,049 (+)	NCBI		HuRef
CHM1_1	1	1,253,754 - 1,256,872 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	762,865 - 766,905 (+)	NCBI		T2T-CHM13v2.0

Tas1r3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	155,943,725 - 155,947,810 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	155,943,725 - 155,947,819 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	155,859,268 - 155,863,353 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	155,859,268 - 155,863,362 (-)	Ensembl			mm10	GRCm38
MGSCv37	4	155,233,377 - 155,237,462 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	154,703,068 - 154,707,153 (-)	NCBI		MGSCv36	mm8
Celera	4	158,130,220 - 158,134,291 (-)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	87.65	NCBI

Tas1r3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	9,470,626 - 9,473,780 (-)	Ensembl
ChiLan1.0	NW_004955486	9,469,954 - 9,475,421 (-)	NCBI	ChiLan1.0	ChiLan1.0

TAS1R3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	226,890,211 - 226,893,453 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	225,588,097 - 225,591,870 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	88,514 - 92,505 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	1,287,841 - 1,292,094 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	1,287,841 - 1,292,094 (+)	Ensembl			panPan2	panpan1.1

TAS1R3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	56,503,720 - 56,506,883 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	56,503,720 - 56,506,898 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	56,580,045 - 56,583,207 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	56,705,942 - 56,709,102 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	56,705,942 - 56,709,117 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	56,696,682 - 56,699,843 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	56,588,966 - 56,592,124 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	56,979,204 - 56,982,368 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tas1r3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	27,649,632 - 27,654,945 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936737	1,811,815 - 1,814,982 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936737	1,811,123 - 1,814,982 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TAS1R3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	63,607,990 - 63,617,809 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	63,613,536 - 63,617,831 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	58,111,612 - 58,115,907 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	6	q22-q23	NCBI

TAS1R3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	130,119,451 - 130,122,920 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	130,119,804 - 130,122,903 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666054	34,682,289 - 34,686,282 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tas1r3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	8,279,161 - 8,282,304 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624818	8,279,161 - 8,282,304 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tas1r3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	4,765,966 - 4,770,051 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	31
Interacting mature miRNAs:	37
Transcripts:	ENSRNOT00000026671
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	156396728	172190305	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	160071170	172129029	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	148093485	172129029	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	11	28	100	54	53	22	80	22	6	227	140	10	77	42	63	31	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_130818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF456324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY032620	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000026671 ⟹ ENSRNOP00000026671

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	171,750,937 - 171,754,993 (-)	Ensembl
mRatBN7.2 Ensembl	5	166,469,589 - 166,472,742 (-)	Ensembl
Rnor_6.0 Ensembl	5	173,308,870 - 173,312,023 (-)	Ensembl

RefSeq Acc Id:

NM_130818 ⟹ NP_570831

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,750,937 - 171,754,993 (-)	NCBI
mRatBN7.2	5	166,468,703 - 166,472,759 (-)	NCBI
Rnor_6.0	5	173,308,870 - 173,312,023 (-)	NCBI
Rnor_5.0	5	176,784,486 - 176,787,639 (-)	NCBI
RGSC_v3.4	5	172,718,551 - 172,721,704 (-)	RGD
Celera	5	164,670,308 - 164,673,461 (-)	RGD

Sequence:

show sequence

ATGCCGGGTTTGGCTATCTTGGGCCTCAGTCTGGCTGCTTTCCTGGAGCTTGGGATGGGGTCCT
CTTTGTGTCTGTCACAGCAATTCAAGGCACAAGGGGACTATATATTGGGTGGACTATTTCCCCT
GGGCACAACTGAGGAGGCCACTCTCAACCAGAGAACACAGCCCAACGGCATCCTATGTACCAGG
TTCTCGCCCCTTGGTTTGTTCCTGGCCATGGCTATGAAGATGGCTGTAGAGGAGATCAACAATG
GATCTGCCTTGCTCCCTGGGCTGCGACTGGGCTATGACCTGTTTGACACATGCTCAGAGCCAGT
GGTCACCATGAAGCCCAGCCTCATGTTCATGGCCAAGGTGGGAAGTCAAAGCATTGCTGCCTAC
TGCAACTACACACAGTACCAACCCCGTGTGCTGGCTGTCATTGGTCCCCACTCATCAGAGCTTG
CCCTCATTACAGGCAAGTTCTTCAGCTTCTTCCTCATGCCACAGGTCAGCTATAGTGCCAGCAT
GGATCGGCTAAGTGACCGGGAAACATTTCCATCCTTCTTCCGCACAGTGCCCAGTGACCGGGTG
CAGCTGCAGGCCGTTGTGACACTGTTGCAGAATTTCAGCTGGAACTGGGTGGCTGCCTTAGGTA
GTGATGATGACTATGGCCGGGAAGGTCTGAGCATCTTTTCTGGTCTGGCCAACTCACGAGGTAT
CTGCATTGCACACGAGGGCCTGGTGCCACAACATGACACTAGTGGCCAACAATTGGGCAAGGTG
GTGGATGTGCTACGCCAAGTGAACCAAAGCAAAGTACAGGTGGTGGTGCTGTTTGCATCTGCCC
GTGCTGTCTACTCCCTTTTTAGCTACAGCATCCTTCATGACCTCTCACCCAAGGTATGGGTGGC
CAGTGAGTCCTGGCTGACCTCTGACCTGGTCATGACACTTCCCAATATTGCCCGTGTGGGCACT
GTTCTTGGGTTTCTGCAGCGCGGTGCCCTACTGCCTGAATTTTCCCATTATGTGGAGACTCGCC
TTGCCCTAGCTGCTGACCCAACATTCTGTGCCTCCCTGAAAGCTGAGTTGGATCTGGAGGAGCG
CGTGATGGGGCCACGCTGTTCACAATGTGACTACATCATGCTACAGAACCTGTCATCTGGGCTG
ATGCAGAACCTATCAGCTGGGCAGTTGCACCACCAAATATTTGCAACCTATGCAGCTGTGTACA
GTGTGGCTCAGGCCCTTCACAACACCCTGCAGTGCAATGTCTCACATTGCCACACATCAGAGCC
TGTTCAACCCTGGCAGCTCCTGGAGAACATGTACAATATGAGTTTCCGTGCTCGAGACTTGACA
CTGCAGTTTGATGCCAAAGGGAGTGTAGACATGGAATATGACCTGAAGATGTGGGTGTGGCAGA
GCCCTACACCTGTACTACATACTGTAGGCACCTTCAACGGCACCCTTCAGCTGCAGCACTCGAA
AATGTATTGGCCAGGCAACCAGGTGCCAGTCTCCCAGTGCTCCCGGCAGTGCAAAGATGGCCAG
GTGCGCAGAGTAAAGGGCTTTCATTCCTGCTGCTATGACTGTGTGGACTGCAAGGCAGGGAGCT
ACCGGAAGCATCCAGATGACTTCACCTGTACTCCATGTGGCAAGGATCAGTGGTCCCCAGAAAA
AAGCACAACCTGCTTACCTCGCAGGCCCAAGTTTCTGGCTTGGGGGGAGCCAGCTGTGCTGTCA
CTTCTCCTGCTGCTTTGCCTGGTGCTGGGCCTGACACTGGCTGCCCTGGGGCTCTTTGTCCACT
ACTGGGACAGCCCTCTTGTTCAGGCCTCAGGTGGGTCACTGTTCTGCTTTGGCCTGATCTGCCT
AGGCCTCTTCTGCCTCAGTGTCCTTCTGTTCCCAGGACGACCACGCTCTGCCAGCTGCCTTGCC
CAACAACCAATGGCTCACCTCCCTCTCACAGGCTGCCTGAGCACACTCTTCCTGCAAGCAGCCG
AGATCTTTGTGGAGTCTGAGCTGCCACTGAGTTGGGCAAACTGGCTCTGCAGCTACCTTCGGGG
CCCCTGGGCTTGGCTGGTGGTACTGCTGGCCACTCTTGTGGAGGCTGCACTATGTGCCTGGTAC
TTGATGGCTTTCCCTCCAGAGGTGGTGACAGATTGGCAGGTGCTGCCCACGGAGGTACTGGAAC
ACTGCCGCATGCGTTCCTGGGTCAGCCTGGGCTTGGTGCACATCACCAATGCAGTGTTAGCTTT
CCTCTGCTTTCTGGGCACTTTCCTGGTACAGAGCCAGCCTGGTCGCTATAACCGTGCCCGTGGC
CTCACCTTCGCCATGCTAGCTTATTTCATCATCTGGGTCTCTTTTGTGCCCCTCCTGGCTAATG
TGCAGGTGGCCTACCAGCCAGCTGTGCAGATGGGTGCTATCTTATTCTGTGCCCTGGGCATCCT
GGCCACCTTCCACCTGCCCAAATGCTATGTACTTCTGTGGCTGCCAGAGCTCAACACCCAGGAG
TTCTTCCTGGGAAGGAGCCCCAAGGAAGCATCAGATGGGAATAGTGGTAGTAGTGAGGCAACTC
GGGGACACAGTGAATGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_570831	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAK51601	(Get FASTA)	NCBI Sequence Viewer
	AAM10636	(Get FASTA)	NCBI Sequence Viewer
	EDL81337	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026671
	ENSRNOP00000026671.1
GenBank Protein	Q923K1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_570831 ⟸ NM_130818
- Peptide Label:	precursor
- UniProtKB:	Q923K1 (UniProtKB/Swiss-Prot), A6IUT6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGLAILGLSLAAFLELGMGSSLCLSQQFKAQGDYILGGLFPLGTTEEATLNQRTQPNGILCTR FSPLGLFLAMAMKMAVEEINNGSALLPGLRLGYDLFDTCSEPVVTMKPSLMFMAKVGSQSIAAY CNYTQYQPRVLAVIGPHSSELALITGKFFSFFLMPQVSYSASMDRLSDRETFPSFFRTVPSDRV QLQAVVTLLQNFSWNWVAALGSDDDYGREGLSIFSGLANSRGICIAHEGLVPQHDTSGQQLGKV VDVLRQVNQSKVQVVVLFASARAVYSLFSYSILHDLSPKVWVASESWLTSDLVMTLPNIARVGT VLGFLQRGALLPEFSHYVETRLALAADPTFCASLKAELDLEERVMGPRCSQCDYIMLQNLSSGL MQNLSAGQLHHQIFATYAAVYSVAQALHNTLQCNVSHCHTSEPVQPWQLLENMYNMSFRARDLT LQFDAKGSVDMEYDLKMWVWQSPTPVLHTVGTFNGTLQLQHSKMYWPGNQVPVSQCSRQCKDGQ VRRVKGFHSCCYDCVDCKAGSYRKHPDDFTCTPCGKDQWSPEKSTTCLPRRPKFLAWGEPAVLS LLLLLCLVLGLTLAALGLFVHYWDSPLVQASGGSLFCFGLICLGLFCLSVLLFPGRPRSASCLA QQPMAHLPLTGCLSTLFLQAAEIFVESELPLSWANWLCSYLRGPWAWLVVLLATLVEAALCAWY LMAFPPEVVTDWQVLPTEVLEHCRMRSWVSLGLVHITNAVLAFLCFLGTFLVQSQPGRYNRARG LTFAMLAYFIIWVSFVPLLANVQVAYQPAVQMGAILFCALGILATFHLPKCYVLLWLPELNTQE FFLGRSPKEASDGNSGSSEATRGHSE hide sequence

Ensembl Acc Id:

ENSRNOP00000026671 ⟸ ENSRNOT00000026671

Protein Domains

G-protein coupled receptors family 3 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q923K1-F1-model_v2	AlphaFold	Q923K1	1-858	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620539	AgrOrtholog
BioCyc Gene	G2FUF-38892	BioCyc
Ensembl Genes	ENSRNOG00000019589	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000026671	ENTREZGENE
	ENSRNOT00000026671.3	UniProtKB/Swiss-Prot
Gene3D-CATH	2.10.50.30	UniProtKB/Swiss-Prot
	3.40.50.2300	UniProtKB/Swiss-Prot
InterPro	ANF_lig-bd_rcpt	UniProtKB/Swiss-Prot
	GPCR_3	UniProtKB/Swiss-Prot
	GPCR_3_9-Cys_dom	UniProtKB/Swiss-Prot
	GPCR_3_9-Cys_sf	UniProtKB/Swiss-Prot
	GPCR_3_C	UniProtKB/Swiss-Prot
	GPCR_3_Ca_sens_rcpt-rel	UniProtKB/Swiss-Prot
	GPCR_3_CS	UniProtKB/Swiss-Prot
	Peripla_BP_I	UniProtKB/Swiss-Prot
KEGG Report	rno:170634	UniProtKB/Swiss-Prot
NCBI Gene	170634	ENTREZGENE
PANTHER	PTHR24061	UniProtKB/Swiss-Prot
	TASTE RECEPTOR TYPE 1 MEMBER 3	UniProtKB/Swiss-Prot
Pfam	7tm_3	UniProtKB/Swiss-Prot
	ANF_receptor	UniProtKB/Swiss-Prot
	NCD3G	UniProtKB/Swiss-Prot
PhenoGen	Tas1r3	PhenoGen
PRINTS	CASENSINGR	UniProtKB/Swiss-Prot
	GPCRMGR	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F3_2	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F3_4	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000019589	RatGTEx
Superfamily-SCOP	SSF53822	UniProtKB/Swiss-Prot
UniProt	A6IUT6	ENTREZGENE, UniProtKB/TrEMBL
	Q923K1	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-23	Tas1r3	taste 1 receptor member 3	Tas1r3	taste receptor, type 1, member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Tas1r3	taste receptor, type 1, member 3			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Tas1r3	taste receptor, type 1, member 3			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_function	heterodimeric sweet taste receptor	634155

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD