Acacb (acetyl-CoA carboxylase beta) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Acacb (acetyl-CoA carboxylase beta) Rattus norvegicus
Analyze
Symbol: Acacb
Name: acetyl-CoA carboxylase beta
RGD ID: 620500
Description: Enables biotin binding activity. Involved in several processes, including carboxylic acid metabolic process; intracellular aspartate homeostasis; and intracellular glutamate homeostasis. Part of mitochondrial fatty acid beta-oxidation multienzyme complex. Used to study steatotic liver disease. Biomarker of metabolic dysfunction-associated steatotic liver disease and obesity. Orthologous to human ACACB (acetyl-CoA carboxylase beta); PARTICIPATES IN fatty acid biosynthetic pathway; insulin signaling pathway; propanoate metabolic pathway; INTERACTS WITH (+)-catechin; (+)-schisandrin B; (R)-carnitine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Acc2; acetyl-CoA carboxylase 2; acetyl-Coenzyme A carboxylase 2; acetyl-Coenzyme A carboxylase beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bw128 Bw132 Foco6 Foco10 Foco20
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,026,394 - 48,138,214 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1248,026,394 - 48,138,214 (-)EnsemblGRCr8
mRatBN7.21242,365,800 - 42,477,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,366,548 - 42,457,655 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1243,534,259 - 43,644,789 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,147,852 - 44,258,379 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,208,360 - 43,318,896 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,127,149 - 48,238,969 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,127,149 - 48,238,887 (-)Ensemblrn6Rnor6.0
Rnor_5.01249,914,427 - 50,000,957 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41243,388,679 - 43,492,993 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1243,976,897 - 44,062,163 (-)NCBICelera
RGSC_v3.11243,252,066 - 43,356,381 (-)NCBI
Cytogenetic Map12q16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-beta-thujone  (ISO)
(+)-catechin  (EXP)
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
(R)-camphor  (ISO)
(R)-carnitine  (EXP)
(R)-linalyl acetate  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,8-cineole  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
acetamide  (EXP)
Acetyl tributyl citrate  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
AICA ribonucleotide  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (EXP,ISO)
ammonium chloride  (EXP)
ampicillin  (ISO)
aristolochic acids  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
aspartame  (ISO)
atorvastatin calcium  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
camphor  (ISO)
cantharidin  (ISO)
capsaicin  (EXP)
carbon nanotube  (ISO)
carnitine  (EXP)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
curcumin  (ISO)
cyanocob(III)alamin  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
D-mannitol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (EXP,ISO)
fenofibrate  (ISO)
fipronil  (ISO)
folic acid  (ISO)
fructose  (EXP,ISO)
furan  (ISO)
genistein  (ISO)
glucose  (ISO)
glycine betaine  (ISO)
glyphosate  (ISO)
GSK-J4  (ISO)
GW 4064  (ISO)
imidacloprid  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
linalool  (ISO)
linalyl acetate  (ISO)
lipopolysaccharide  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
metronidazole  (ISO)
mevalonic acid  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (EXP)
neomycin  (ISO)
nickel atom  (ISO)
nordihydroguaiaretic acid  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
olaparib  (ISO)
oleic acid  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
puerarin  (ISO)
resveratrol  (ISO)
rimonabant  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sabinene  (ISO)
SB 431542  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
spathulenol  (ISO)
streptozocin  (EXP)
sunitinib  (EXP,ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tenofovir disoproxil fumarate  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)
zinc atom  (EXP,ISO)
zinc sulfate  (EXP)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Isolation and characterization of cDNA encoding rat heart type acetyl-CoA carboxylase. Abe K, etal., Biochim Biophys Acta 1998 Jul 9;1398(3):347-52.
2. Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms. Abu-Elheiga L, etal., J Biol Chem 1997 Apr 18;272(16):10669-77.
3. The subcellular localization of acetyl-CoA carboxylase 2. Abu-Elheiga L, etal., Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1444-9.
4. Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion. Choi YS, etal., J Mol Cell Cardiol. 2016 Nov;100:64-71. doi: 10.1016/j.yjmcc.2016.09.001. Epub 2016 Sep 28.
5. [Effect of truncal vagotomy on the exocrine function of the pancreas in the dog] Dabrowski Z, etal., Pol Tyg Lek 1978 Jul 10;33(28):1093-5.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. The cytoskeleton in 'couch potato-ism': Insights from a murine model of impaired actin dynamics. Gertz K, etal., Exp Neurol. 2018 Aug;306:34-44. doi: 10.1016/j.expneurol.2018.04.004. Epub 2018 Apr 21.
8. Cloning of human acetyl-CoA carboxylase-beta and its unique features. Ha J, etal., Proc Natl Acad Sci U S A 1996 Oct 15;93(21):11466-70.
9. Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals. Harwood HJ Jr, etal., J Biol Chem. 2003 Sep 26;278(39):37099-111. Epub 2003 Jul 3.
10. Fasting for 3 days during the suckling-weaning transient period in male rats induces metabolic abnormalities in the liver and is associated with impaired glucose tolerance in adulthood. Ikeda M, etal., Eur J Nutr. 2016 Apr;55(3):1059-67. doi: 10.1007/s00394-015-0919-9. Epub 2015 May 6.
11. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
12. The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment. Liang Y, etal., Metabolism. 2006 Oct;55(10):1411-9.
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise. Park H, etal., J Biol Chem 2002 Sep 6;277(36):32571-7.
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. Pharmacological biotin supplementation maintains biotin status and function in rats administered dietary carbamazepine. Rathman SC, etal., J Nutr. 2003 Sep;133(9):2857-62.
17. GOA pipeline RGD automated data pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Metabolic Remodeling Promotes Cardiac Hypertrophy by Directing Glucose to Aspartate Biosynthesis. Ritterhoff J, etal., Circ Res. 2020 Jan 17;126(2):182-196. doi: 10.1161/CIRCRESAHA.119.315483. Epub 2019 Nov 11.
21. Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. Savage DB, etal., J Clin Invest. 2006 Mar;116(3):817-24. Epub 2006 Feb 16.
22. Carnitine Supplementation Attenuates Sunitinib-Induced Inhibition of AMP-Activated Protein Kinase Downstream Signals in Cardiac Tissues. Sayed-Ahmed MM, etal., Cardiovasc Toxicol. 2019 Aug;19(4):344-356. doi: 10.1007/s12012-018-9500-0.
23. Assignment of acetyl-CoA carboxylase-beta (ACACB) to human chromosome band 12q24.1 by in situ hybridization. Ullrich CK, etal., Cytogenet Cell Genet 1997;77(3-4):176-7.
24. The Warble Fly Orders. Watson J, Vet Rec. 1978 Oct 14;103(16):354-5.
25. Identification of a second human acetyl-CoA carboxylase gene. Widmer J, etal., Biochem J 1996 Jun 15;316 ( Pt 3):915-22.
26. WY14643 improves left ventricular myocardial mitochondrial and systolic functions in obese rats under chronic persistent hypoxia via the PPARα pathway. Yan J, etal., Life Sci. 2021 Feb 1;266:118888. doi: 10.1016/j.lfs.2020.118888. Epub 2020 Dec 10.
27. Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis. Zhang H, etal., PLoS One. 2015 Sep 22;10(9):e0138203. doi: 10.1371/journal.pone.0138203. eCollection 2015.
Additional References at PubMed
PMID:11283375   PMID:12764144   PMID:12920182   PMID:15579580   PMID:15590647   PMID:15677334   PMID:16854592   PMID:17210641   PMID:17956983   PMID:18255222   PMID:18487439   PMID:18614015  
PMID:19236960   PMID:19618481   PMID:20457939   PMID:20952656   PMID:25195817   PMID:26976583  


Genomics

Comparative Map Data
Acacb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,026,394 - 48,138,214 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1248,026,394 - 48,138,214 (-)EnsemblGRCr8
mRatBN7.21242,365,800 - 42,477,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,366,548 - 42,457,655 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1243,534,259 - 43,644,789 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,147,852 - 44,258,379 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,208,360 - 43,318,896 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,127,149 - 48,238,969 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,127,149 - 48,238,887 (-)Ensemblrn6Rnor6.0
Rnor_5.01249,914,427 - 50,000,957 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41243,388,679 - 43,492,993 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1243,976,897 - 44,062,163 (-)NCBICelera
RGSC_v3.11243,252,066 - 43,356,381 (-)NCBI
Cytogenetic Map12q16NCBI
ACACB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812109,111,189 - 109,268,226 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12109,116,587 - 109,268,226 (+)Ensemblhg38GRCh38
GRCh3712109,548,994 - 109,706,031 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,061,585 - 108,190,414 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3412108,039,930 - 108,166,887NCBI
Celera12109,201,352 - 109,330,479 (+)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12106,595,722 - 106,724,234 (+)NCBIHuRef
CHM1_112109,544,852 - 109,673,937 (+)NCBICHM1_1
T2T-CHM13v2.012109,086,220 - 109,243,208 (+)NCBIT2T-CHM13v2.0
Acacb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,284,748 - 114,388,822 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,284,596 - 114,388,822 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385114,146,321 - 114,250,761 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,146,535 - 114,250,761 (+)Ensemblmm10GRCm38
MGSCv375114,615,527 - 114,700,767 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365114,426,517 - 114,510,733 (+)NCBIMGSCv36mm8
Celera5111,267,324 - 111,357,484 (+)NCBICelera
Cytogenetic Map5FNCBI
Acacb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,308,192 - 10,426,076 (+)Ensembl
ChiLan1.0NW_00495545510,282,308 - 10,427,439 (+)NCBIChiLan1.0ChiLan1.0
ACACB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210117,176,414 - 117,335,004 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112117,172,919 - 117,331,402 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012106,692,668 - 106,845,490 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112110,086,374 - 110,239,847 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,086,374 - 110,239,847 (+)EnsemblpanPan2panpan1.1
ACACB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,763,531 - 17,895,319 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,747,362 - 17,894,400 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2617,906,250 - 18,037,960 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02618,106,936 - 18,239,349 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2618,106,944 - 18,239,179 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,115,480 - 18,247,107 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02618,097,758 - 18,229,980 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02618,116,847 - 18,248,772 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Acacb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,422,223 - 144,525,063 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936769950,845 - 1,051,887 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936769950,970 - 1,053,671 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACACB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,621,574 - 41,739,916 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11441,621,574 - 41,739,916 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,153,373 - 44,271,216 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACACB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111104,325,250 - 104,488,567 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11104,349,573 - 104,488,003 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037140,614,337 - 140,773,620 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acacb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,307,541 - 12,424,897 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474712,287,817 - 12,426,340 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Acacb
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11639,714,187 - 39,801,434 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:202
Count of miRNA genes:86
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000000821, ENSRNOT00000067975
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)124413955852308831Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 73 59 6 337 173 11 139 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB004329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM237460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ493871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB872073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB873333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB875204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB879714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB888449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB921258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC929482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC930742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC932613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC937123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC945858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC978667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000000821   ⟹   ENSRNOP00000000821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1248,026,394 - 48,138,214 (-)Ensembl
mRatBN7.2 Ensembl1242,366,548 - 42,457,655 (-)Ensembl
Rnor_6.0 Ensembl1248,128,408 - 48,218,955 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000067975   ⟹   ENSRNOP00000060736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1248,026,394 - 48,138,214 (-)Ensembl
mRatBN7.2 Ensembl1242,366,548 - 42,457,655 (-)Ensembl
Rnor_6.0 Ensembl1248,128,405 - 48,218,955 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078868   ⟹   ENSRNOP00000071816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1248,026,394 - 48,138,214 (-)Ensembl
mRatBN7.2 Ensembl1242,366,548 - 42,457,655 (-)Ensembl
Rnor_6.0 Ensembl1248,127,149 - 48,238,887 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080557   ⟹   ENSRNOP00000073473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1248,026,394 - 48,138,214 (-)Ensembl
mRatBN7.2 Ensembl1242,366,548 - 42,457,655 (-)Ensembl
Rnor_6.0 Ensembl1248,128,405 - 48,218,955 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113138   ⟹   ENSRNOP00000094530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1248,026,394 - 48,109,533 (-)Ensembl
mRatBN7.2 Ensembl1242,366,548 - 42,448,848 (-)Ensembl
RefSeq Acc Id: NM_053922   ⟹   NP_446374
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,394 - 48,138,214 (-)NCBI
mRatBN7.21242,365,800 - 42,477,651 (-)NCBI
Rnor_6.01248,128,405 - 48,218,955 (-)NCBI
Rnor_5.01249,914,427 - 50,000,957 (-)NCBI
RGSC_v3.41243,388,679 - 43,492,993 (-)RGD
Celera1243,976,897 - 44,062,163 (-)RGD
Sequence:
RefSeq Acc Id: XM_017598242   ⟹   XP_017453731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,138,052 (-)NCBI
mRatBN7.21242,365,800 - 42,477,509 (-)NCBI
Rnor_6.01248,127,149 - 48,238,969 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598243   ⟹   XP_017453732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,128,286 (-)NCBI
mRatBN7.21242,365,800 - 42,467,804 (-)NCBI
Rnor_6.01248,127,149 - 48,229,431 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598245   ⟹   XP_017453734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,127,503 (-)NCBI
mRatBN7.21242,365,800 - 42,466,946 (-)NCBI
Rnor_6.01248,127,149 - 48,228,340 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598246   ⟹   XP_017453735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,138,052 (-)NCBI
mRatBN7.21242,365,800 - 42,477,508 (-)NCBI
Rnor_6.01248,127,149 - 48,238,969 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598247   ⟹   XP_017453736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,109,437 (-)NCBI
mRatBN7.21242,365,800 - 42,448,872 (-)NCBI
Rnor_6.01248,127,149 - 48,210,393 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598248   ⟹   XP_017453737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,103,500 (-)NCBI
mRatBN7.21242,365,800 - 42,442,942 (-)NCBI
Rnor_6.01248,127,149 - 48,205,056 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089031   ⟹   XP_038944959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,052,423 - 48,138,101 (-)NCBI
mRatBN7.21242,391,852 - 42,477,587 (-)NCBI
RefSeq Acc Id: XM_063271014   ⟹   XP_063127084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,138,052 (-)NCBI
RefSeq Acc Id: XM_063271015   ⟹   XP_063127085
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,127,679 (-)NCBI
RefSeq Acc Id: XM_063271016   ⟹   XP_063127086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,127,694 (-)NCBI
RefSeq Acc Id: XM_063271017   ⟹   XP_063127087
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,109,436 (-)NCBI
RefSeq Acc Id: XM_063271018   ⟹   XP_063127088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,109,436 (-)NCBI
RefSeq Acc Id: XM_063271019   ⟹   XP_063127089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,026,395 - 48,095,233 (-)NCBI
Protein Sequences
Protein RefSeqs NP_446374 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453731 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453732 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453734 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453735 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453736 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453737 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944959 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127084 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127085 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127086 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127087 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127088 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127089 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABF48724 (Get FASTA)   NCBI Sequence Viewer  
  BAA25799 (Get FASTA)   NCBI Sequence Viewer  
  CAJ87423 (Get FASTA)   NCBI Sequence Viewer  
  CBF60093 (Get FASTA)   NCBI Sequence Viewer  
  CBF60826 (Get FASTA)   NCBI Sequence Viewer  
  CBF61974 (Get FASTA)   NCBI Sequence Viewer  
  CBF64155 (Get FASTA)   NCBI Sequence Viewer  
  CBF68369 (Get FASTA)   NCBI Sequence Viewer  
  CBF95619 (Get FASTA)   NCBI Sequence Viewer  
  CBU85337 (Get FASTA)   NCBI Sequence Viewer  
  CBU85946 (Get FASTA)   NCBI Sequence Viewer  
  CBU86850 (Get FASTA)   NCBI Sequence Viewer  
  CBU89031 (Get FASTA)   NCBI Sequence Viewer  
  CBU93243 (Get FASTA)   NCBI Sequence Viewer  
  CBV09139 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000000821.7
  ENSRNOP00000060736
  ENSRNOP00000060736.2
  ENSRNOP00000071816
  ENSRNOP00000071816.3
  ENSRNOP00000073473
  ENSRNOP00000073473.2
  ENSRNOP00000094530
  ENSRNOP00000094530.2
RefSeq Acc Id: NP_446374   ⟸   NM_053922
- Peptide Label: precursor
- UniProtKB: Q1HEC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453735   ⟸   XM_017598246
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K1F2 (UniProtKB/TrEMBL),   Q1HEC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453731   ⟸   XM_017598242
- Peptide Label: isoform X1
- UniProtKB: Q1HEC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453732   ⟸   XM_017598243
- Peptide Label: isoform X1
- UniProtKB: Q1HEC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453734   ⟸   XM_017598245
- Peptide Label: isoform X1
- UniProtKB: Q1HEC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453736   ⟸   XM_017598247
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ART3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453737   ⟸   XM_017598248
- Peptide Label: isoform X6
- UniProtKB: A0A8I6ART3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073473   ⟸   ENSRNOT00000080557
Ensembl Acc Id: ENSRNOP00000060736   ⟸   ENSRNOT00000067975
Ensembl Acc Id: ENSRNOP00000000821   ⟸   ENSRNOT00000000821
Ensembl Acc Id: ENSRNOP00000071816   ⟸   ENSRNOT00000078868
RefSeq Acc Id: XP_038944959   ⟸   XM_039089031
- Peptide Label: isoform X10
Ensembl Acc Id: ENSRNOP00000094530   ⟸   ENSRNOT00000113138
RefSeq Acc Id: XP_063127084   ⟸   XM_063271014
- Peptide Label: isoform X3
- UniProtKB: Q1HEC0 (UniProtKB/TrEMBL),   A0A0G2K5L6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127086   ⟸   XM_063271016
- Peptide Label: isoform X4
- UniProtKB: Q1HEC0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127085   ⟸   XM_063271015
- Peptide Label: isoform X2
- UniProtKB: Q1HEC0 (UniProtKB/TrEMBL),   A0A0G2K1F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127088   ⟸   XM_063271018
- Peptide Label: isoform X8
- UniProtKB: A0A8I6ART3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127087   ⟸   XM_063271017
- Peptide Label: isoform X7
- UniProtKB: A0A8I6ART3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127089   ⟸   XM_063271019
- Peptide Label: isoform X9
- UniProtKB: A0A8I6ART3 (UniProtKB/TrEMBL)
Protein Domains
ATP-grasp   Biotin carboxylation   CoA carboxyltransferase C-terminal   CoA carboxyltransferase N-terminal   Lipoyl-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PSQ0-F1-model_v2 AlphaFold E9PSQ0 1-2460 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620500 AgrOrtholog
BioCyc Gene G2FUF-18941 BioCyc
BioCyc Pathway PWY0-1264 [biotin-carboxyl carrier protein assembly] BioCyc
  PWY66-429 [fatty acid biosynthesis initiation (mitochondria)] BioCyc
BioCyc Pathway Image PWY0-1264 BioCyc
  PWY66-429 BioCyc
Ensembl Genes ENSRNOG00000000658 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000821.8 UniProtKB/TrEMBL
  ENSRNOT00000067975 ENTREZGENE
  ENSRNOT00000067975.6 UniProtKB/TrEMBL
  ENSRNOT00000078868 ENTREZGENE
  ENSRNOT00000078868.3 UniProtKB/TrEMBL
  ENSRNOT00000080557 ENTREZGENE
  ENSRNOT00000080557.3 UniProtKB/TrEMBL
  ENSRNOT00000113138 ENTREZGENE
  ENSRNOT00000113138.2 UniProtKB/TrEMBL
Gene3D-CATH 2-enoyl-CoA Hydratase, Chain A, domain 1 UniProtKB/TrEMBL
  2.40.50.100 UniProtKB/TrEMBL
  3.30.1490.20 UniProtKB/TrEMBL
  3.40.50.20 UniProtKB/TrEMBL
  ATP-grasp fold, B domain UniProtKB/TrEMBL
  Biotin dependent carboxylase carboxyltransferase UniProtKB/TrEMBL
  PreATP-grasp domain UniProtKB/TrEMBL
InterPro ACCA UniProtKB/TrEMBL
  ACCA_BT UniProtKB/TrEMBL
  AcCoA_carboxyl UniProtKB/TrEMBL
  AcCoA_COase_cen UniProtKB/TrEMBL
  ATP-grasp UniProtKB/TrEMBL
  ATP_grasp_subdomain_1 UniProtKB/TrEMBL
  Biotin_carboxylation_dom UniProtKB/TrEMBL
  Biotin_COase_C UniProtKB/TrEMBL
  Biotin_lipoyl UniProtKB/TrEMBL
  CarbamoylP_synth_lsu_ATP-bd UniProtKB/TrEMBL
  CarbamoylP_synth_lsu_N UniProtKB/TrEMBL
  ClpP/crotonase-like_dom UniProtKB/TrEMBL
  COA_CT_C UniProtKB/TrEMBL
  COA_CT_N UniProtKB/TrEMBL
  PreATP-grasp-like UniProtKB/TrEMBL
  Rudment_hybrid_motif UniProtKB/TrEMBL
  Single_hybrid_motif UniProtKB/TrEMBL
KEGG Report rno:116719 UniProtKB/TrEMBL
NCBI Gene 116719 ENTREZGENE
PANTHER ACETYL-COA CARBOXYLASE 2 UniProtKB/TrEMBL
  ACETYL-COA CARBOXYLASE, ISOFORM A UniProtKB/TrEMBL
Pfam ACC_central UniProtKB/TrEMBL
  ACCA_BT UniProtKB/TrEMBL
  Biotin_carb_C UniProtKB/TrEMBL
  Biotin_lipoyl UniProtKB/TrEMBL
  Carboxyl_trans UniProtKB/TrEMBL
  CPSase_L_chain UniProtKB/TrEMBL
  CPSase_L_D2 UniProtKB/TrEMBL
PhenoGen Acacb PhenoGen
PROSITE ATP_GRASP UniProtKB/TrEMBL
  BIOTINYL_LIPOYL UniProtKB/TrEMBL
  COA_CT_CTER UniProtKB/TrEMBL
  COA_CT_NTER UniProtKB/TrEMBL
  CPSASE_1 UniProtKB/TrEMBL
  CPSASE_2 UniProtKB/TrEMBL
  PS50979 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000658 RatGTEx
SMART Biotin_carb_C UniProtKB/TrEMBL
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
  Hybrid_motif UniProtKB/TrEMBL
  PreATP-grasp-like UniProtKB/TrEMBL
  Rudmnt_hyb_motif UniProtKB/TrEMBL
  SSF52096 UniProtKB/TrEMBL
UniProt A0A0G2K1F2 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K5L6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ART3 ENTREZGENE, UniProtKB/TrEMBL
  B7ZDJ4_RAT UniProtKB/TrEMBL
  D3ZBE2_RAT UniProtKB/TrEMBL
  E9PSQ0_RAT UniProtKB/TrEMBL
  O70151_RAT UniProtKB/TrEMBL
  Q1HEC0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-28 Acacb  acetyl-CoA carboxylase beta  Acacb  acetyl-Coenzyme A carboxylase beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Acacb  acetyl-Coenzyme A carboxylase beta      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Acacb  acetyl-Coenzyme A carboxylase beta      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed at high levels in heart, skeletal muscle, and brown adipose tissue 631890
gene_regulation synergystically regulated by sterol regulatory element-binding protein-1 (SREBP1). 631890