Tle3 (TLE family member 3, transcriptional corepressor) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Tle3 (TLE family member 3, transcriptional corepressor) Rattus norvegicus
Analyze
Symbol: Tle3
Name: TLE family member 3, transcriptional corepressor
RGD ID: 620292
Description: Predicted to enable transcription coactivator activity and transcription corepressor activity. Involved in regulation of DNA-templated transcription. Located in nucleus. Orthologous to human TLE3 (TLE family member 3, transcriptional corepressor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Esp3; rTLE3; transducin-like enhancer of split 3; transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 3 homolog of Drosophila; transducin-like enhancer of split 3, E(spl) homolog; transducin-like enhancer of split 3, E(spl) homolog (Drosophila); transducin-like enhancer of split 3, homolog of Drosophila; transducin-like enhancer of split 3, homolog of Drosophila E(spl); transducin-like enhancer protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8870,753,182 - 70,799,080 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl870,753,383 - 70,799,074 (+)EnsemblGRCr8
mRatBN7.2861,857,791 - 61,903,505 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl861,858,200 - 61,903,493 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx867,372,008 - 67,417,314 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0865,644,540 - 65,689,846 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0863,514,430 - 63,559,736 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0866,296,509 - 66,342,186 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl866,296,883 - 66,342,176 (+)Ensemblrn6Rnor6.0
Rnor_5.0866,038,401 - 66,084,101 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4865,485,758 - 65,531,052 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera861,283,289 - 61,329,326 (+)NCBICelera
RGSC_v3.1865,504,811 - 65,550,106 (+)NCBI
Cytogenetic Map8q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
indometacin  (ISO)
leflunomide  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nitrates  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
beta-catenin-TCF complex  (IEA,ISO)
chromatin  (IEA,ISO,ISS)
chromosome  (IEA)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IDA,IEA,ISO)
transcription regulator complex  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. rTLE3, a newly identified transducin-like enhancer of split, is induced by depolarization in brain. Feldman JD, etal., J Neurochem 2000 May;74(5):1838-47.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPAR¿ specifies lipid storage versus thermogenic gene programs. Villanueva CJ, etal., Cell Metab. 2013 Mar 5;17(3):423-35. doi: 10.1016/j.cmet.2013.01.016.
7. Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta. Wang JC, etal., J Biol Chem. 2000 Jun 16;275(24):18418-23.
Additional References at PubMed
PMID:12477932   PMID:28296634  


Genomics

Comparative Map Data
Tle3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8870,753,182 - 70,799,080 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl870,753,383 - 70,799,074 (+)EnsemblGRCr8
mRatBN7.2861,857,791 - 61,903,505 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl861,858,200 - 61,903,493 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx867,372,008 - 67,417,314 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0865,644,540 - 65,689,846 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0863,514,430 - 63,559,736 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0866,296,509 - 66,342,186 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl866,296,883 - 66,342,176 (+)Ensemblrn6Rnor6.0
Rnor_5.0866,038,401 - 66,084,101 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4865,485,758 - 65,531,052 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera861,283,289 - 61,329,326 (+)NCBICelera
RGSC_v3.1865,504,811 - 65,550,106 (+)NCBI
Cytogenetic Map8q24NCBI
TLE3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381570,047,790 - 70,097,917 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1570,047,790 - 70,098,176 (-)Ensemblhg38GRCh38
GRCh371570,340,129 - 70,390,256 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361568,127,597 - 68,177,310 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341568,129,472 - 68,176,212NCBI
Celera1547,229,949 - 47,279,848 (-)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1547,172,994 - 47,222,697 (-)NCBIHuRef
CHM1_11570,458,399 - 70,508,108 (-)NCBICHM1_1
T2T-CHM13v2.01567,870,017 - 67,920,141 (-)NCBIT2T-CHM13v2.0
Tle3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39961,279,608 - 61,325,779 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl961,279,665 - 61,325,772 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38961,372,326 - 61,418,497 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl961,372,366 - 61,418,497 (+)Ensemblmm10GRCm38
MGSCv37961,220,173 - 61,266,304 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36961,171,678 - 61,214,990 (+)NCBIMGSCv36mm8
Celera958,595,799 - 58,641,869 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map933.27NCBI
Tle3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554506,603,879 - 6,645,602 (+)Ensembl
ChiLan1.0NW_0049554506,604,915 - 6,645,305 (+)NCBIChiLan1.0ChiLan1.0
TLE3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21659,314,453 - 59,364,223 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11563,478,532 - 63,528,272 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01549,000,145 - 49,050,246 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11567,768,456 - 67,817,589 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1567,770,176 - 67,817,320 (-)EnsemblpanPan2panpan1.1
TLE3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13033,803,719 - 33,895,204 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3033,803,734 - 33,896,525 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3033,736,086 - 33,829,040 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03034,003,206 - 34,096,536 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3034,002,751 - 34,096,324 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13033,924,905 - 34,019,688 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03033,988,554 - 34,081,625 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03034,285,719 - 34,332,753 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tle3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640111,835,017 - 111,882,172 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647129,682,947 - 29,731,031 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647129,682,313 - 29,730,229 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLE3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1167,808,510 - 167,855,911 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11167,808,508 - 167,855,913 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21185,894,943 - 185,941,304 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TLE3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12613,355,915 - 13,406,446 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2613,357,058 - 13,406,641 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666048128,080,846 - 128,131,599 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tle3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247813,594,254 - 3,631,487 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247813,593,197 - 3,632,741 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tle3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1855,674,852 - 55,720,224 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tle3
184 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:665
Count of miRNA genes:275
Interacting mature miRNAs:355
Transcripts:ENSRNOT00000018467
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85899169791341052Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)84754141992541419Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85899169791341052Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85899169791341052Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001436403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF186092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC097419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018467   ⟹   ENSRNOP00000018467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl870,753,777 - 70,799,070 (+)Ensembl
mRatBN7.2 Ensembl861,858,200 - 61,903,493 (+)Ensembl
Rnor_6.0 Ensembl866,296,883 - 66,342,176 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101556   ⟹   ENSRNOP00000084240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl870,754,630 - 70,798,437 (+)Ensembl
mRatBN7.2 Ensembl861,858,713 - 61,902,848 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102975   ⟹   ENSRNOP00000092843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl870,753,777 - 70,799,070 (+)Ensembl
mRatBN7.2 Ensembl861,858,200 - 61,903,493 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108424   ⟹   ENSRNOP00000079710
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl870,753,383 - 70,799,074 (+)Ensembl
mRatBN7.2 Ensembl861,859,053 - 61,903,493 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111574   ⟹   ENSRNOP00000085293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl861,881,387 - 61,903,493 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000133027   ⟹   ENSRNOP00000103648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl870,754,290 - 70,793,937 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000164911   ⟹   ENSRNOP00000109823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl870,753,383 - 70,797,592 (+)Ensembl
RefSeq Acc Id: NM_053400   ⟹   NP_445852
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,777 - 70,799,070 (+)NCBI
mRatBN7.2861,858,200 - 61,903,493 (+)NCBI
Rnor_6.0866,296,883 - 66,342,176 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
RGSC_v3.4865,485,758 - 65,531,052 (+)RGD
Celera861,283,289 - 61,329,326 (+)RGD
Sequence:
RefSeq Acc Id: XM_006243211   ⟹   XP_006243273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,371 - 70,799,080 (+)NCBI
mRatBN7.2861,857,791 - 61,903,505 (+)NCBI
Rnor_6.0866,296,509 - 66,340,436 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243212   ⟹   XP_006243274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,851 - 61,903,505 (+)NCBI
Rnor_6.0866,296,509 - 66,340,436 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243213   ⟹   XP_006243275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,852 - 61,903,505 (+)NCBI
Rnor_6.0866,296,510 - 66,340,436 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243214   ⟹   XP_006243276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,851 - 61,903,505 (+)NCBI
Rnor_6.0866,296,511 - 66,342,186 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243215   ⟹   XP_006243277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,852 - 61,903,505 (+)NCBI
Rnor_6.0866,296,511 - 66,342,186 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243216   ⟹   XP_006243278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,852 - 61,903,505 (+)NCBI
Rnor_6.0866,296,510 - 66,340,436 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243217   ⟹   XP_006243279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,852 - 61,903,505 (+)NCBI
Rnor_6.0866,296,509 - 66,340,436 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243218   ⟹   XP_006243280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,852 - 61,903,505 (+)NCBI
Rnor_6.0866,296,511 - 66,340,436 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243219   ⟹   XP_006243281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,852 - 61,903,505 (+)NCBI
Rnor_6.0866,296,512 - 66,342,186 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243220   ⟹   XP_006243282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,851 - 61,903,505 (+)NCBI
Rnor_6.0866,296,511 - 66,342,186 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243221   ⟹   XP_006243283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,852 - 61,903,505 (+)NCBI
Rnor_6.0866,296,511 - 66,342,186 (+)NCBI
Rnor_5.0866,038,401 - 66,084,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766347   ⟹   XP_008764569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
mRatBN7.2861,857,852 - 61,903,505 (+)NCBI
Rnor_6.0866,296,511 - 66,342,186 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063266230   ⟹   XP_063122300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
RefSeq Acc Id: XM_063266231   ⟹   XP_063122301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,182 - 70,799,080 (+)NCBI
RefSeq Acc Id: XM_063266232   ⟹   XP_063122302
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,371 - 70,799,080 (+)NCBI
RefSeq Acc Id: XM_063266233   ⟹   XP_063122303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,371 - 70,799,080 (+)NCBI
RefSeq Acc Id: XM_063266234   ⟹   XP_063122304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8870,753,354 - 70,799,080 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001423332 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423333 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423334 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423335 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423336 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423337 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423338 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423339 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423340 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423341 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423342 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423343 (Get FASTA)   NCBI Sequence Viewer  
  NP_445852 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243273 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243274 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243275 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243276 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243277 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243278 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243279 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243280 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243281 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243282 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243283 (Get FASTA)   NCBI Sequence Viewer  
  XP_008764569 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122300 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122301 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122302 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122303 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122304 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF75590 (Get FASTA)   NCBI Sequence Viewer  
  AAH97419 (Get FASTA)   NCBI Sequence Viewer  
  EDL95733 (Get FASTA)   NCBI Sequence Viewer  
  EDL95734 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018467
  ENSRNOP00000079710
  ENSRNOP00000109823
GenBank Protein Q9JIT3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445852   ⟸   NM_053400
- UniProtKB: Q9JIT3 (UniProtKB/Swiss-Prot),   A6J560 (UniProtKB/TrEMBL),   A0A8I5ZNN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243276   ⟸   XM_006243214
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006243274   ⟸   XM_006243212
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZNN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243275   ⟸   XM_006243213
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006243277   ⟸   XM_006243215
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006243278   ⟸   XM_006243216
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006243281   ⟸   XM_006243219
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_006243279   ⟸   XM_006243217
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZNN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243282   ⟸   XM_006243220
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZNN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243283   ⟸   XM_006243221
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: XP_006243273   ⟸   XM_006243211
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZNN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243280   ⟸   XM_006243218
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_008764569   ⟸   XM_008766347
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000018467   ⟸   ENSRNOT00000018467
Ensembl Acc Id: ENSRNOP00000085293   ⟸   ENSRNOT00000111574
Ensembl Acc Id: ENSRNOP00000084240   ⟸   ENSRNOT00000101556
Ensembl Acc Id: ENSRNOP00000079710   ⟸   ENSRNOT00000108424
Ensembl Acc Id: ENSRNOP00000092843   ⟸   ENSRNOT00000102975
RefSeq Acc Id: XP_063122300   ⟸   XM_063266230
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063122301   ⟸   XM_063266231
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063122304   ⟸   XM_063266234
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063122302   ⟸   XM_063266232
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063122303   ⟸   XM_063266233
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZNN2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109823   ⟸   ENSRNOT00000164911
Ensembl Acc Id: ENSRNOP00000103648   ⟸   ENSRNOT00000133027
Protein Domains
Groucho/TLE N-terminal Q-rich

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JIT3-F1-model_v2 AlphaFold Q9JIT3 1-764 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696047
Promoter ID:EPDNEW_R6572
Type:single initiation site
Name:Tle3_1
Description:transducin-like enhancer of split 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0866,296,954 - 66,297,014EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620292 AgrOrtholog
BioCyc Gene G2FUF-30189 BioCyc
Ensembl Genes ENSRNOG00000013013 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000018467 ENTREZGENE
  ENSRNOT00000108424 ENTREZGENE
  ENSRNOT00000164911 ENTREZGENE
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7454629 IMAGE-MGC_LOAD
InterPro Groucho/TLE_N UniProtKB/Swiss-Prot
  Groucho_enhance UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_CS UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:84424 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114465 IMAGE-MGC_LOAD
NCBI Gene 84424 ENTREZGENE
PANTHER PTHR10814 UniProtKB/Swiss-Prot
  TRANSDUCIN-LIKE ENHANCER PROTEIN 3 UniProtKB/Swiss-Prot
Pfam TLE_N UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Tle3 PhenoGen
PRINTS GROUCHOFAMLY UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013013 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A8I5ZNN2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXM2_RAT UniProtKB/TrEMBL
  A0A8I6AEG3_RAT UniProtKB/TrEMBL
  A0A8L2QA95_RAT UniProtKB/TrEMBL
  A0ABK0LG92_RAT UniProtKB/TrEMBL
  A0ABK0M505_RAT UniProtKB/TrEMBL
  A6J560 ENTREZGENE, UniProtKB/TrEMBL
  A6J561_RAT UniProtKB/TrEMBL
  Q4V8F0_RAT UniProtKB/TrEMBL
  Q9JIT3 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-12-04 Tle3  TLE family member 3, transcriptional corepressor  Tle3  transducin-like enhancer of split 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-03-27 Tle3  transducin-like enhancer of split 3  Tle3  transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Tle3  transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)  Tle3  transducin-like enhancer of split 3, homolog of Drosophila E(spl)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Tle3  transducin-like enhancer of split 3, homolog of Drosophila E(spl)  Tle3  transducin-like enhancer of split 3, E(spl) homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Tle3  transducin-like enhancer of split 3, E(spl) homolog (Drosophila)    transducin-like enhancer of split 3, homolog of Drosophila  Name updated 1299863 APPROVED
2002-08-07 Tle3  transducin-like enhancer of split 3, homolog of Drosophila      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation expression is induced by depolarization and forskolin 634434