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Gene: Cabin1 (calcineurin binding protein 1) Rattus norvegicus

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Symbol:

Cabin1

Name:

calcineurin binding protein 1

RGD ID:

620263

Description:

Enables protein domain specific binding activity and protein phosphatase 2B binding activity. Involved in negative regulation of apoptotic process and response to activity. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in ovarian carcinoma. Orthologous to human CABIN1 (calcineurin binding protein 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Cain; calcineurin inhibitor; calcineurin-binding protein cabin-1; calcineurin-binding protein cabin-1-like; LOC103689948

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CABIN1 (calcineurin binding protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Cabin1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cabin1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CABIN1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CABIN1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cabin1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CABIN1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CABIN1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cabin1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cabin1 (calcineurin binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CABIN1 (calcineurin binding protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cabin1 (calcineurin binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cabin1 (calcineurin binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	picd-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder)
Caenorhabditis elegans (roundworm):	picd-1	Alliance	DIOPT (OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	cabin1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	12,892,750 - 13,014,801 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	12,892,771 - 13,014,800 (+)	Ensembl				GRCr8
mRatBN7.2	20	12,893,314 - 13,015,357 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	12,893,358 - 13,015,357 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	13,599,937 - 13,721,941 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	12,960,879 - 13,082,888 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	13,432,984 - 13,555,133 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	13,836,032 - 13,963,003 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	13,836,030 - 13,963,003 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	15,924,052 - 15,942,759 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	20	16,025,717 - 16,151,225 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	13,444,801 - 13,569,453 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	14,383,605 - 14,503,982 (+)	NCBI		Celera
RGSC_v3.1	20	13,445,046 - 13,569,680 (-)	NCBI
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cardiomegaly (ISO)

Experimental Arthritis (ISO)

ovarian carcinoma (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

ATP (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bisphenol F (EXP)

cadmium atom (EXP)

cadmium dichloride (EXP)

caffeine (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

choline (ISO)

clobetasol (ISO)

clopidogrel (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

folic acid (ISO)

FR900359 (ISO)

irinotecan (ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

methamphetamine (ISO)

methoxychlor (EXP)

mifepristone (ISO)

N,N-diethyl-m-toluamide (EXP)

nitrates (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

permethrin (EXP)

phenylephrine (EXP)

quercetin (ISO)

raloxifene (EXP)

selenium atom (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

tamoxifen (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

tris(2-butoxyethyl) phosphate (ISO)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IBA,IEA)

negative regulation of apoptotic process (IMP)

negative regulation of transcription by RNA polymerase II (IBA)

nucleosome assembly (ISO)

response to activity (IEP)

Cellular Component

cytoplasm (IEA)

nucleoplasm (ISO)

nucleus (IBA,IEA)

Molecular Function

nucleosome binding (IBA)

protein binding (IPI)

protein domain specific binding (IMP)

protein phosphatase 2B binding (IDA)

protein phosphatase inhibitor activity (TAS)

transcription corepressor activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	DNA hypermethylation, Her-2/neu overexpression and p53 mutations in ovarian carcinoma.	Feng Q, etal., Gynecol Oncol. 2008 Nov;111(2):320-9. doi: 10.1016/j.ygyno.2008.07.036. Epub 2008 Aug 30.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Gene expression profiling of exercise-induced cardiac hypertrophy in rats.	Iemitsu M, etal., Acta Physiol Scand. 2005 Dec;185(4):259-70.
4.	Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death.	Kim MJ, etal., Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9870-5.
5.	Cain, a novel physiologic protein inhibitor of calcineurin.	Lai MM, etal., J Biol Chem 1998 Jul 17;273(29):18325-31.
6.	The calcineurin-binding protein cain is a negative regulator of synaptic vesicle endocytosis.	Lai MM, etal., J Biol Chem. 2000 Nov 3;275(44):34017-20.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Comprehensive gene review and curation	RGD comprehensive gene curation
13.	G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214.	van Deursen J, etal., EMBO J 1996 Oct 15;15(20):5574-83.
14.	Regulation of inflammatory responses and fibroblast-like synoviocyte apoptosis by calcineurin-binding protein 1 in mice with collagen-induced arthritis.	Yi JK, etal., Arthritis Rheum. 2012 Jul;64(7):2191-200. doi: 10.1002/art.34398.

Additional References at PubMed

PMID:14718166	PMID:26400065	PMID:29190603	PMID:29368245	PMID:32000560

Genomics

Comparative Map Data

Cabin1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	12,892,750 - 13,014,801 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	12,892,771 - 13,014,800 (+)	Ensembl				GRCr8
mRatBN7.2	20	12,893,314 - 13,015,357 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	12,893,358 - 13,015,357 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	13,599,937 - 13,721,941 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	12,960,879 - 13,082,888 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	13,432,984 - 13,555,133 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	13,836,032 - 13,963,003 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	13,836,030 - 13,963,003 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	15,924,052 - 15,942,759 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	20	16,025,717 - 16,151,225 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	13,444,801 - 13,569,453 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	14,383,605 - 14,503,982 (+)	NCBI		Celera
RGSC_v3.1	20	13,445,046 - 13,569,680 (-)	NCBI
Cytogenetic Map	20	p12	NCBI

CABIN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	24,011,304 - 24,178,628 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	24,011,192 - 24,178,634 (+)	Ensembl			hg38	GRCh38
GRCh37	22	24,407,754 - 24,574,596 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	22,737,765 - 22,904,596 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	22	22,732,318 - 22,899,150	NCBI
Celera	22	8,207,658 - 8,374,995 (+)	NCBI		Celera
Cytogenetic Map	22	q11.23	NCBI
HuRef	22	7,355,977 - 7,523,706 (+)	NCBI		HuRef
CHM1_1	22	24,366,024 - 24,533,337 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	24,472,930 - 24,640,242 (+)	NCBI		T2T-CHM13v2.0

Cabin1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	75,481,944 - 75,600,194 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	75,481,946 - 75,600,175 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	75,646,110 - 75,764,357 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	75,646,112 - 75,764,341 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	75,108,855 - 75,227,102 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	75,089,828 - 75,208,073 (-)	NCBI		MGSCv36	mm8
Celera	10	76,690,803 - 76,809,131 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	38.56	NCBI

Cabin1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	8,162,315 - 8,312,909 (-)	Ensembl
ChiLan1.0	NW_004955455	8,162,365 - 8,312,932 (-)	NCBI	ChiLan1.0	ChiLan1.0

CABIN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	33,795,295 - 33,963,647 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	36,529,019 - 36,697,375 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	4,816,411 - 4,984,760 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	22,902,776 - 23,070,598 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	22,927,572 - 23,070,165 (+)	Ensembl			panPan2	panpan1.1

CABIN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	28,366,264 - 28,517,570 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	28,366,265 - 28,517,656 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	27,440,625 - 27,591,723 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	29,770,268 - 29,921,946 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	29,770,270 - 29,921,917 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	27,854,246 - 28,005,988 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	27,470,762 - 27,622,599 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	28,460,896 - 28,611,816 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cabin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	141,723,046 - 141,863,600 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936619	890,299 - 1,030,899 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936619	890,474 - 1,030,914 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CABIN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	49,686,196 - 49,787,688 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	49,686,196 - 49,787,723 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	53,128,158 - 53,229,937 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CABIN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	7,127,370 - 7,289,054 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	7,127,401 - 7,289,050 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666100	73,032 - 234,603 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cabin1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	10,110,370 - 10,257,276 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	10,110,476 - 10,257,165 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cabin1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	11,681,347 - 11,802,459 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cabin1
481 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	66
Count of miRNA genes:	55
Interacting mature miRNAs:	59
Transcripts:	ENSRNOT00000001659
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	4189476	49189476	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	1	26925056	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1	33724594	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26128279	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8043920	29865039	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600300	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1533083	46533083	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24164241	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	1	34066551	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29193376	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	1	27341128	Rat
1598870	Bp289	Blood pressure QTL 289	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	8216359	53216359	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29193376	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29193376	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29193376	Rat
1581577	Pur15	Proteinuria QTL 15	4.38	0.0002	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	20	8043920	15089182	Rat
1598858	Cm61	Cardiac mass QTL 61	3.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	20	8216359	53216359	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29193376	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1	14100378	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	12243242	49189476	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578510	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600300	Rat

Markers in Region

BF390741

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	12,984,027 - 12,984,193 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	13,931,680 - 13,931,845	NCBI	Rnor6.0
Rnor_5.0	20	16,119,902 - 16,120,067	UniSTS	Rnor5.0
RGSC_v3.4	20	13,475,960 - 13,476,125	UniSTS	RGSC3.4
Celera	20	14,472,769 - 14,472,934	UniSTS
Cytogenetic Map	20	p12	UniSTS

RH128071

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	13,015,044 - 13,015,247 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	13,962,691 - 13,962,893	NCBI	Rnor6.0
Rnor_5.0	20	16,150,913 - 16,151,115	UniSTS	Rnor5.0
RGSC_v3.4	20	13,444,911 - 13,445,113	UniSTS	RGSC3.4
Celera	20	14,503,670 - 14,503,872	UniSTS
RH 3.4 Map	20	154.36	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005497345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF061947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DV716961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001659 ⟹ ENSRNOP00000001659

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	12,892,771 - 13,014,800 (+)	Ensembl
mRatBN7.2 Ensembl	20	12,993,393 - 13,015,356 (+)	Ensembl
Rnor_6.0 Ensembl	20	13,836,030 - 13,963,003 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093157 ⟹ ENSRNOP00000076295

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	12,892,771 - 13,014,800 (+)	Ensembl
mRatBN7.2 Ensembl	20	12,893,358 - 13,015,357 (+)	Ensembl
Rnor_6.0 Ensembl	20	13,836,030 - 13,963,003 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093229

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	13,955,670 - 13,962,098 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093587 ⟹ ENSRNOP00000076268

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	13,940,877 - 13,951,820 (+)	Ensembl

RefSeq Acc Id:

NM_053575 ⟹ NP_446027

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	12,892,793 - 13,014,801 (+)	NCBI
mRatBN7.2	20	12,893,360 - 13,015,357 (+)	NCBI
Rnor_6.0	20	13,836,032 - 13,963,003 (+)	NCBI
Rnor_5.0	20	16,025,717 - 16,151,225 (+)	NCBI
RGSC_v3.4	20	13,444,801 - 13,569,453 (-)	RGD
Celera	20	14,383,605 - 14,503,982 (+)	NCBI

Sequence:

show sequence

CTCGGAGGTCCGTGCAGGGCTCCGGTGAGCGCGAGGAGGTGGGAACACGCGACGCCCGCTCTCC
ATTACGGGCGCGGTGGGCCGAAGCCTGGCTCGAGACCCGAAGGCGCTGACAAGGACCTTCTGGC
CACGCCTGCTCCTCCGCGCGCCCCGCCGCTGCGCCCGGAGGCGCCCAGGGTGGGTCACTGGGAC
CGCAGCTCGAAGCCATCCCTTTCTGTGCGTCCTTTCATTCACCTTCACAGCAGCCCAGAGAGGG
ACTGTCAACTGGCACATCCCCCACCAGTGATGGGAAGTGATCCTCCGTGGTGGCGCTGAATCTC
TGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACAATTGAAGATGACCATGAAGGAAG
CTTTAAAAGTCACAAAATCCAGACAAAGGAGGCTCAGGAAGCAGAAGCCTTTGCCCTATACCAC
AAGGCCCTGGATCTACAGAAACATGACAGGTTTGAGGAGTCTGCCAAGGCCTACCATGAACTCC
TGGAGGCTCGCCTGCTGCGAGAGGCAGTTTCATCCGGAGATGAGAAGGAAGGGCTGAAGCACCC
TGGACTGATACTGAAATATTCTACGTATAAGAACCTGGCCCAGCTGGCAGCCCAGCGGGAGGAC
CTGGAGACAGCCATGGAGTTTTATTTGGAGGCCGTGATGCTGGATTCCACAGACGTCAACCTTT
GGTACAAGATTGGACATGTGGCCCTGAGGCTCATCCGACTTCCCCTGGCTCGCCATGCTTTTGA
GGAAGGGCTCCGGTGTAATCCTGACCACTGGCCCTGCTTGGACAACCTCATCACTGTTTTGTAC
ACCCTCAGCGATTACACAACATGTCTTTACTTCATCTGCAAAGCACTGGAGAAAGACTGCCGCT
ACAGCAAAGGCCTGGTTCTCAAGGAGAAGATTTTTGAAGAGCAACCTTGTCTCCGAAAGGACTC
ACTCCGAATGTTCCTCAAATGTGACATGTCAGTTCACGAGGTGTCAGTGAATGCAGCAGAGACA
CAGGCCATTGTAGACGAGGCTCTGGGGCTGCGGAAGAAGAGGCAGGCGTTGATCGTGCGGGAAA
AGGAGCCAGACCTGAAACTAGTGCAGCCCATCCCTTTCTTCACGTGGAAGTGCCTTGGAGAGAG
CTTGCTTGCCATGTACAATCACCTCACCACGTGTGAGCCTCCCAGGCCCAGCCTGGGCAAGAGG
ATTGACCTGTCTGACTACCAGGATCCCAGCCAGCTGCTAGCCCCCTCCGTCGTGGTTACTCCTG
TCAGTGTGGTCCAGCCAAGTCCTGTTTGCACCAATCCAACTGTTGCTGTGGCCGAGCCTGTGCT
CTCCTACACCTCTGTGACCACAACCAGCTTCCCACTGCACAGTCCTGGCCTGCTGGACACGGGC
ACTCCTATGGGTGATGTTTCCGGAGGAGATAAATCTAAAAAAGGGGTGAAGCGTAAGAAGACTT
TAGAGGAAAGTGGGGAGACAGCAAAGCGGAGGTCTGCCCGTGTCCGCAACACCAAGTGCAAAAA
AGAAGAGAAGGTGGATTTCCAGGGGCTTCTGGTAAAGTTCCTGCCGTCCAGGTTAAGAAAACTG
GACCCTGAGGAGGAAGATGATCCATTTAACAACTATGAAGTTCAGTCAGAAGCCAAACTGGAGA
GCTTCTCGAACGTGGGACCTCATCGACTGTCCTTCGATTCAGCCACATTCATGGAATCTGAGAA
GCAGGATGTGCATGCGTTCCTGATGGAGAACCTGACCAATGGGGGCGTCCTGGAGCTCATGATG
CGCTACCTGAAGAGCATGGGCCACAAGTTCCTGCTGAAGTGGCCCCCAGGCCTGGCGGAGGTCG
TACTTAGCGTCTACCACAGCTGGAGGAGGCACAGTACCAGCCTGCCCAACCCATTGCTGAGGGA
CTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTTTCCTGCATGGAGCTCCAACTG
GACCAGTGGCTTCTGACCAAAGGCAGAAGCTCCACGGTGTCTCCCCGGAACTGCCCTGCTGGTG
TGGTGACAGGCAGGTTTGGGCCAGACTTCCCAGGAACCCACTGCCTGGGTGACCTCCTGCAGCT
GTCATTTGCGTCATCTCAGCGGGATCTGTTTGAGGACGGCTGGCTGGAGTTTGTGGTCCGTGTT
TACTGGCTGAAGGCACGTTTCTTGGCACTACAGGGCGATATGGAGCAAGCTTTGGAGAACTATG
ATATCTGCACAGAGATACTCCAGAGCTCCACGGCTCTCCAAGCCCAGGCAGGGGCTGAGCAAAG
GGACATTGTCATCCGGCTGCCCAACCTGCACAATGACTCCATTGTTTCTCTGGAGGAAATTGAT
AAGAACCTGAAGTCTCTGGAAAGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTTTGAGGCGG
GCGACTACAAGGCTGTGGTGCAGCTGCTCCGGCCCACTCTGTGCACCAGTGGCTTTGACCGAGC
CAAACACCTGGAGTTTATGACTTCCATTCCCGAGAGGCCGGCCCAGCTGCTTCTGCTGCAGGAC
TCTCTGCTCCGGCTGGAGGAGCACAGGCAGTGCTTTGAATGCTCTGACGTGGCCCTCAATGAAG
CTGTCCAGCAGATGCTGAACTCGAGTGACTCTGCGGCCAAGGAGGAGTGGGCGGCCACAGTGAC
GCAGCTGCTGCTAGGCATGGAGCAGGCACTGTCATCAGACAGCAGGGGCAGCATCCTGAAGGAG
TCCTCCTCTCCCACGGGCCTTGTCCGGCTCACCAACAACCTCATTCAGGTCATCGACTGCAGCA
TGGCTGTGCAGGAGGAGCCCAAGGAGCCCTATGTCTCCTCCGTGCTGCCCTGGATCATCCTCCA
CAGGATCATCTGGCAGGAGGAAGACACTTTCCGGTCTCTGTGCCACCAGCAGCAGCTCCAGAAC
CCAACGGAAGAAGGGATCTCGGAGATGCCCATGCTCCCATCTTCCCTCATGCTGCTCAACACAG
CACATGAGTACCTGGGCAGGAGGTCCTGGTGCTGCAATTCAGATGGAGCGCTGCTGCGATTCTA
TGTGCACGTTCTCCAAAAGGAGCTTGCTGCGTCTGCCTCTGAGGACACTCACCCCTACAAGGAG
GAGCTGGAGACCGCCTTGGAGCAGTGTTTCTACTGCCTCTACAGCTTCCCCAGCAAGAAGAGCA
AGGCCAGGTACCTGGAGGAGCACTCAGCCCAGCAGGTGGACCTCACCTGGGAGGACGCCCTGTT
CATGTTTGAGTACTTCAAGCCCAAGACCCTCCCTGAGTTTGACAGCTACAAGACCAGCACCGTC
TCCGCGGACTTGGCAAACCTGTTGAAAAGAATCGCCACCATTGTGCCGCGCACAGAGAAGCCCG
CCCTGAGCATGGACAAAGTCTCTGCCTACATTGAGGGAACCTCAGCGGAGGTGCCCTGCCTTCC
TGACGGGGCAGACCCCGCCCCTCCAGTGCTGAATGAGCTCTACTACCTCCTGGCTGACTATCAC
TTCAAAAACAAAGAGCAGTCCAAAGCCATCAAGTTCTACATGCATGACATTTGCATCTGCCCTA
ACAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCGGGCCAGCCGAATTCAGGACAAGCTGAA
CTCAAATGAGCTGAAGAGTGATGGACCCATCTGGAGACATGCCACACCTGTTCTGAACTGCTTC
CGGAGGGCCCTTGAGATTGACAGCTCTAACTTGTCCTTGTGGATTGAGTATGGCACCATGTCCT
ATGCCTTGCACTCATTCGCGTCCCGTCAGCTGAAGCAGTGGCGAGCCGAGCTGCCTCCTGAGGT
TGTGCAGCAGATGGAGGATCGGCGAGACAGCATGCTGGAGACAGCCAGGCACTGTTTCACGTCT
GCAGCCCACTGCGAGGGTGATGGCGATGAGGAGGAGTGGCTCATTCACTACATGCTGGGCAAAG
TGGCCGAGAAGCAGCAGCAGCCGCCGACCGTGTACCTGCTGCACTACCGCCAGGCGGGCCACTA
CTTACACGAGGAGGCCGCCCGCTACCCTAAGAAGATTCACTACCACAACCCGCCCGAGCTGGCC
ATGGAAGCCCTGGAGGTGTACTTCCGGCTCCATGCGTCCATCCTGAAGCTCCTGGGCAAACCTG
ACTCTGGGGTTAGCGCAGAGGTCCTGGTCAGCTTTATGAAGGAAGCAGCAGAAGGACCTTTTGC
CAGGGGCGAGGAGAAGAATACACCTAAAGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGATGAG
GACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTTCCCTCCTCCTCTGGCC
CAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAA
ACCCCGTCAGCAGGCGACGCCGGACGACCGAAGCCAGGACAGCACAGCTGTGGCACTGTCAGAC
TCCAGCTCAACACAGGACTTCTTTAATGAGCCCACAAGTTTGCTGGACGGTTCTCGAAAGCTCC
TTCCAGAGAAGAGGATCTCTGGGCTCAGTGCTCAAGCAGGACCAAGTGGTAAAGACCTTCCAGG
GCCCACAGAGGAAAGAGGAAAAACGGAGGAGTCTTTGGAGAGCACAGAGGCCTTCCGGGTTGTA
GAACCAAGCGTCCAGAAGCCTGTGGCAGATTCCTCGGCCTCTGCTTACATCCCCAGCAAGCCCG
CAGTGTCCACGCCCCCTCCGTGGGATGGGAAGAAGAGGAGTGACCCCCTAGGGGAGCCAGTGGC
TTTCCCTCAGGGGCTGCCAGCAGGTGCTGAGGAACAGCGCCAGTTCCTCACAGAGCAGTGCATC
GCCTCCTTCTGCCTGTGCTTGAGTCGCTTCCCACAGCACTACAAGAGTCTCTACCGGCTGGCCT
TTCTCTACACCTACAGCAAGACTCACCGGAACCTCCAGTGGGCCCGTGATGTGTTGCTAGGCAG
CAGTATCCCATGGCAACAACTGCAGCACATGCCGGCACAGGGGCTCTTCTGCGAGAGGAACAAG
ACCAATTTCTTCAACGGCATCTGGCGGATCCCCGTGGATGAGATTGACCGGCCCGGCAGCTTCG
CCTGGCACATGAACCGCTCCATCGTGCTGCTACTCAAGGTTCTAGCCCAGCTCCGGGACCACAG
CACCCTGTTGAAGGTGTCCTCCATGCTGCAGCGGACACCAGACCAGGGCAAGAAATATCTGCGA
GATGCTGACCGCCAGGTGCTGGCACAGCGCGCCTTCATCCTCACTGTGAAGGTGCTGGAGGACA
CACTGAGTGAGCTTGCAGAGGGGTTAGAGCACCCAGGATCCAAGGCCTGTGGCCTCTCTGGAGC
CAGGATGACCACCGATGTCTCACACAAAGCCAGTCCCGAGGATGGCCAGGAAAGCCTCCCACAC
CCCAAGAAGCTACCTCTAGCTGATGGCTCAGGACCAGGGCCTGAGCCAGGGGGCAAAGTGGGCC
CTCTCCACCAATTGCCAGTGGCCACAGACACAAGGGACAACACAGAGCAGGGTGGGGAGCCGAA
AGACAAAGAGCGTCCCCCGGTGGGGCCCACAGAACCCATGGACACCGGCGAGACTGCTGCTCGC
CACCCAGACTTGGAACCGACGCCACGTCTGTTGCCAGGCCGCCCCCCAAGGGACCGGGGTCCCG
AGAGCCGCTCTGCTGAGCTTTCCCTGGAGGAGCTGAGCATCAGCACCCGGCAGCAGCCTGCCCC
ACTTGTACCATCCCCAGTAACCCCCACCACAGCTGCTCCCACTACCATGGGGGCCAGGGCAGCG
GGGCACCCCGAGGAGGCACCGCCAAGGCCTAATCGAAAGAGGAAACTCCTGCAGGACACAGAGT
CTGGCAAGACGCTCCTTTTGGACGCCTACCGTGTGTGGCAGCAGGGCCAGAAGGCCATGGCCTA
TGACCTGAGCCGCATCGAGAAGATCATGTCGGAGACTTACATGCTCATCAAGCAGGTGGACGAG
GAGACTGCACTGGAGCAGGCTGTGAAGTTCTGTCAGGTCCACCTCGGGGCTGCTGCCCAGAGAC
AGGCCTCAGGAGATGCACCCACTACCCCCAAGCACCCCAAGGACAGCCGAGAGAATTTCTTCCC
TGCAACAGTGGCCCCCTCAGCACCTGACACCACAGCACCTGACGCTCTCCAGCGGCCCAGTGAC
TCCCACCTCAAGCCTGGGTTGGCTGCTGCCATCACCTGCCCTCCCTCAGCATCAGCCTCTACCC
CAGACCCTGGAATTCCCCAGCCACACAGGCCAGAGGCTGTGCCCAGCAGGGCCCCTCTGAGTCC
TGATGGAGAAGAGGTGTCAGGAGTGACAGAGGGTCCCAGCTTTCTATCCCAAGAACCACGGCAC
AGTCACCAGATGAAAATGGCTGCCACTGGTCCCCTGGCCGAGCAGCACTGCTGGCCAGTGGAGG
CTGCTTGCCAGACAGGTGCCGAGCCCACCTTCAGCCAAGCCACCAGCACCAAGGTCCCCAGCAG
TGGAAGTACCCAGACACCTGAGAGCCATCAAGGCAAAACTGAGTCCAGCAGAGCCAAGTCCCGC
CTCCTGCCCAACATGCCAAAGCTGGTGATCCCCTCGGCCACCACCAAGTTCCCCCCTGAGATCA
CCGTCACACCACCTACCCCCACCCTGCTCTCCCCCAAAGGCAGCATCTCAGAGGAGACCAAGCA
GAAGCTGAAGTCTGCCATCCTGTCTGCCCAATCTGCCGCCAATGTGAGGAAGGAGAGCCTGTGC
CAGCCAGCCCTGGAGGTTCTGGAGACATCCAGCCAGGAGTCCTCATTGGAGAGTGAGACAGACG
AGGACGATGACTTTATGGACGTATGACGGGTTCACCCAGAGGCAGGGCCTGGGGTCCCTTTGGT
CCAGACCCTGGGCAAGGCCAGAAGCCTATTGAGGTATGGTTCCCTGTGGTCTCCTAAGCCTGCC
CAGCCCCCTCTTTGCAGCACCCTGCCCTGGCTCAGGCTGTCCAGAGCGTGCTGGTCCAGAGGAC
GGTACGGCCTGTCTTAGGCACATGCACTGCTGTGGTCTGCACAGCCGGGATGCTGCCGCCGCCG
CCGCTTCTTTTTTTAATGAGATACTGACTTTCTCTACAAGCCCGTGTGTACTGACCAGGCCCAC
AGTCCAGTGCCGAGGAGACATCAGGAGCCTAGCTCTCCCCACACCCTTTTTTGTCATTGTTGCT
TCTTTTTCTAATAAAGATGGAAAATGGT

hide sequence

RefSeq Acc Id:

XM_039099130 ⟹ XP_038955058

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	12,892,755 - 13,014,800 (+)	NCBI
mRatBN7.2	20	12,893,317 - 13,015,357 (+)	NCBI

RefSeq Acc Id:

XM_039099132 ⟹ XP_038955060

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	12,892,750 - 12,943,625 (+)	NCBI
mRatBN7.2	20	12,893,314 - 12,944,192 (+)	NCBI

RefSeq Acc Id:

XM_063279580 ⟹ XP_063135650

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	12,892,751 - 12,967,072 (+)	NCBI

RefSeq Acc Id:

XR_005497345

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	12,892,751 - 12,961,755 (+)	NCBI
mRatBN7.2	20	12,893,314 - 12,962,303 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_446027	(Get FASTA)	NCBI Sequence Viewer
	XP_038955058	(Get FASTA)	NCBI Sequence Viewer
	XP_038955060	(Get FASTA)	NCBI Sequence Viewer
	XP_063135650	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC40176	(Get FASTA)	NCBI Sequence Viewer
	EDL97192	(Get FASTA)	NCBI Sequence Viewer
	EDL97193	(Get FASTA)	NCBI Sequence Viewer
	EDL97194	(Get FASTA)	NCBI Sequence Viewer
	EDL97195	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000076295
GenBank Protein	O88480	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_446027 ⟸ NM_053575

- UniProtKB:

O88480 (UniProtKB/Swiss-Prot), A0A1W2Q6J1 (UniProtKB/TrEMBL), A6JKH7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MIRIAALNASSTIEDDHEGSFKSHKIQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLE
ARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWY
KIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYS
KGLVLKEKIFEEQPCLRKDSLRMFLKCDMSVHEVSVNAAETQAIVDEALGLRKKRQALIVREKE
PDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQLLAPSVVVTPVS
VVQPSPVCTNPTVAVAEPVLSYTSVTTTSFPLHSPGLLDTGTPMGDVSGGDKSKKGVKRKKTLE
ESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQSEAKLESF
SNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGVLELMMRYLKSMGHKFLLKWPPGLAEVVL
SVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSTVSPRNCPAGVV
TGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDI
CTEILQSSTALQAQAGAEQRDIVIRLPNLHNDSIVSLEEIDKNLKSLERCQSLEEIQRLFEAGD
YKAVVQLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLEEHRQCFECSDVALNEAV
QQMLNSSDSAAKEEWAATVTQLLLGMEQALSSDSRGSILKESSSPTGLVRLTNNLIQVIDCSMA
VQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGISEMPMLPSSLMLLNTAH
EYLGRRSWCCNSDGALLRFYVHVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKA
RYLEEHSAQQVDLTWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPAL
SMDKVSAYIEGTSAEVPCLPDGADPAPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNR
FDSWAGMALARASRIQDKLNSNELKSDGPIWRHATPVLNCFRRALEIDSSNLSLWIEYGTMSYA
LHSFASRQLKQWRAELPPEVVQQMEDRRDSMLETARHCFTSAAHCEGDGDEEEWLIHYMLGKVA
EKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDS
GVSAEVLVSFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPG
LTSPPYTATPIDHDYVKCKKPRQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLDGSRKLLP
EKRISGLSAQAGPSGKDLPGPTEERGKTEESLESTEAFRVVEPSVQKPVADSSASAYIPSKPAV
STPPPWDGKKRSDPLGEPVAFPQGLPAGAEEQRQFLTEQCIASFCLCLSRFPQHYKSLYRLAFL
YTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAW
HMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTL
SELAEGLEHPGSKACGLSGARMTTDVSHKASPEDGQESLPHPKKLPLADGSGPGPEPGGKVGPL
HQLPVATDTRDNTEQGGEPKDKERPPVGPTEPMDTGETAARHPDLEPTPRLLPGRPPRDRGPES
RSAELSLEELSISTRQQPAPLVPSPVTPTTAAPTTMGARAAGHPEEAPPRPNRKRKLLQDTESG
KTLLLDAYRVWQQGQKAMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAAAQRQA
SGDAPTTPKHPKDSRENFFPATVAPSAPDTTAPDALQRPSDSHLKPGLAAAITCPPSASASTPD
PGIPQPHRPEAVPSRAPLSPDGEEVSGVTEGPSFLSQEPRHSHQMKMAATGPLAEQHCWPVEAA
CQTGAEPTFSQATSTKVPSSGSTQTPESHQGKTESSRAKSRLLPNMPKLVIPSATTKFPPEITV
TPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDED
DDFMDV

hide sequence

Ensembl Acc Id:

ENSRNOP00000076268 ⟸ ENSRNOT00000093587

Ensembl Acc Id:

ENSRNOP00000076295 ⟸ ENSRNOT00000093157

Ensembl Acc Id:

ENSRNOP00000001659 ⟸ ENSRNOT00000001659

RefSeq Acc Id:	XP_038955060 ⟸ XM_039099132
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038955058 ⟸ XM_039099130
- Peptide Label:	isoform X1
- UniProtKB:	O88480 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063135650 ⟸ XM_063279580
- Peptide Label:	isoform X2

Protein Domains

Calcineurin-binding protein cabin-1 MEF2-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O88480-F1-model_v2	AlphaFold	O88480	1-2182	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701536

Promoter ID:

EPDNEW_R12060

Type:

initiation region

Name:

Cabin1_2

Description:

calcineurin binding protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R12061

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	13,836,000 - 13,836,060	EPDNEW

RGD ID:

13701537

Promoter ID:

EPDNEW_R12061

Type:

multiple initiation site

Name:

Cabin1_1

Description:

calcineurin binding protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R12060

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	13,941,109 - 13,941,169	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620263	AgrOrtholog
BioCyc Gene	G2FUF-4156	BioCyc
Ensembl Genes	ENSRNOG00000001237	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000093157	ENTREZGENE
Gene3D-CATH	1.25.40.10	UniProtKB/Swiss-Prot
InterPro	Hir3/CABIN1	UniProtKB/Swiss-Prot
	MEF2-bd	UniProtKB/Swiss-Prot
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot
	TPR_repeat	UniProtKB/Swiss-Prot
KEGG Report	rno:94165	UniProtKB/Swiss-Prot
NCBI Gene	94165	ENTREZGENE
PANTHER	CALCINEURIN-BINDING PROTEIN CABIN-1	UniProtKB/Swiss-Prot
	PTHR15502	UniProtKB/Swiss-Prot
Pfam	MEF2_binding	UniProtKB/Swiss-Prot
PhenoGen	Cabin1	PhenoGen
PROSITE	TPR	UniProtKB/Swiss-Prot
	TPR_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000001237	RatGTEx
SMART	TPR	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48452	UniProtKB/Swiss-Prot
UniProt	A0A1W2Q6J1	ENTREZGENE, UniProtKB/TrEMBL
	A6JKH7	ENTREZGENE, UniProtKB/TrEMBL
	A6JKH8_RAT	UniProtKB/TrEMBL
	A6JKI0_RAT	UniProtKB/TrEMBL
	CABIN_RAT	UniProtKB/Swiss-Prot
	G3V650_RAT	UniProtKB/TrEMBL
	O88480	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Cabin1	calcineurin binding protein 1	LOC103689948	calcineurin-binding protein cabin-1-like	Data merged from RGD:9130189	737654	PROVISIONAL
2014-08-25	LOC103689948	calcineurin-binding protein cabin-1-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-12-07	Cabin1	calcineurin binding protein 1	Cain	cain	Symbol and Name updated	1299863	APPROVED
2002-08-07	Cain	cain			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	predominantly expressed in neuronal tissues	632368
gene_protein	240-kDa	632368

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD