Mgat2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Mgat2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase) Rattus norvegicus
Analyze
Symbol: Mgat2
Name: alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
RGD ID: 620098
Description: Enables alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity and carbohydrate binding activity. Predicted to be involved in protein N-linked glycosylation via asparagine. Predicted to be located in cytoplasmic side of rough endoplasmic reticulum membrane. Predicted to be part of large ribosomal subunit. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIa. Orthologous to human MGAT2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-1,2-N-acetylglucosaminyltransferase II; beta-12-N-acetylglucosaminyltransferase II; glcNAc-T II; GNT-II; Gnt2; mannoside acetylglucosaminyltransferase 2; mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; MGC93297; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8693,392,416 - 93,394,905 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl693,390,555 - 93,395,176 (+)EnsemblGRCr8
mRatBN7.2687,656,360 - 87,658,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl687,656,349 - 87,658,177 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx688,056,244 - 88,058,733 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0688,355,679 - 88,358,168 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0687,795,430 - 87,797,919 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0691,476,698 - 91,479,187 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl691,476,698 - 91,479,183 (+)Ensemblrn6Rnor6.0
Rnor_5.06100,935,605 - 100,938,094 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4691,137,262 - 91,139,751 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera686,155,587 - 86,158,076 (+)NCBICelera
RGSC_v3.1691,140,717 - 91,143,203 (+)NCBI
Cytogenetic Map6q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
alachlor  (EXP)
alpha-phellandrene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antimony(0)  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[ghi]perylene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chromium atom  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
indometacin  (ISO)
isobutanol  (ISO)
limonene  (EXP)
lycopene  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (EXP)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
phenobarbital  (ISO)
phenol  (ISO)
phenytoin  (EXP)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (ISO)
tetracycline  (ISO)
tetraphene  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Control of glycoprotein synthesis. Kinetic mechanism, substrate specificity, and inhibition characteristics of UDP-N-acetylglucosamine:alpha-D-mannoside beta 1-2 N-acetylglucosaminyltransferase II from rat liver. Bendiak B and Schachter H, J Biol Chem. 1987 Apr 25;262(12):5784-90.
2. Congenital disorders of glycosylation IIa cause growth retardation, mental retardation, and facial dysmorphism. Cormier-Daire V, etal., J Med Genet. 2000 Nov;37(11):875-7.
3. Molecular cloning and expression of cDNA encoding the rat UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II. D'Agostaro GA, etal., J Biol Chem 1995 Jun 23;270(25):15211-21.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14. Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development. Tan J, etal., Am J Hum Genet. 1996 Oct;59(4):810-7.
15. Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. Wang Y, etal., Glycobiology. 2001 Dec;11(12):1051-70.
Additional References at PubMed
PMID:7635144   PMID:12417412   PMID:15489334   PMID:19946888   PMID:20378551   PMID:24930395   PMID:25164810   PMID:29666272  


Genomics

Comparative Map Data
Mgat2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8693,392,416 - 93,394,905 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl693,390,555 - 93,395,176 (+)EnsemblGRCr8
mRatBN7.2687,656,360 - 87,658,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl687,656,349 - 87,658,177 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx688,056,244 - 88,058,733 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0688,355,679 - 88,358,168 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0687,795,430 - 87,797,919 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0691,476,698 - 91,479,187 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl691,476,698 - 91,479,183 (+)Ensemblrn6Rnor6.0
Rnor_5.06100,935,605 - 100,938,094 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4691,137,262 - 91,139,751 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera686,155,587 - 86,158,076 (+)NCBICelera
RGSC_v3.1691,140,717 - 91,143,203 (+)NCBI
Cytogenetic Map6q24NCBI
MGAT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381449,620,799 - 49,623,481 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1449,620,799 - 49,623,481 (+)Ensemblhg38GRCh38
GRCh371450,087,517 - 50,090,199 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361449,157,239 - 49,159,949 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341449,157,246 - 49,159,924NCBI
Celera1429,947,307 - 29,950,017 (+)NCBICelera
Cytogenetic Map14q21.3NCBI
HuRef1430,204,620 - 30,207,330 (+)NCBIHuRef
CHM1_11450,026,493 - 50,029,203 (+)NCBICHM1_1
T2T-CHM13v2.01443,819,023 - 43,821,705 (+)NCBIT2T-CHM13v2.0
Mgat2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391269,230,932 - 69,233,547 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1269,230,931 - 69,233,544 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381269,184,158 - 69,186,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1269,184,157 - 69,186,770 (+)Ensemblmm10GRCm38
MGSCv371270,285,145 - 70,287,760 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361270,102,818 - 70,104,852 (+)NCBIMGSCv36mm8
Celera1270,275,998 - 70,278,613 (+)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1228.73NCBI
Mgat2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540913,030,569 - 13,031,912 (-)Ensembl
ChiLan1.0NW_00495540913,029,578 - 13,032,406 (-)NCBIChiLan1.0ChiLan1.0
MGAT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21550,745,231 - 50,747,895 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11449,961,730 - 49,964,401 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01430,199,011 - 30,201,566 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11448,508,936 - 48,511,644 (+)NCBIPanPan1.1PanPan1.1panPan2
MGAT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1826,244,894 - 26,247,960 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl826,245,407 - 26,246,747 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha825,999,094 - 26,001,888 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0826,423,188 - 26,425,981 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl826,423,230 - 26,425,166 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1826,078,562 - 26,081,356 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0826,152,187 - 26,154,981 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0826,469,320 - 26,472,110 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mgat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864058,288,862 - 58,292,089 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936583398,190 - 399,533 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936583396,787 - 399,697 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGAT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1179,477,992 - 179,479,801 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11179,478,464 - 179,479,804 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21199,864,843 - 199,866,183 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1q23-q27NCBI
MGAT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12426,660,554 - 26,663,264 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2426,661,049 - 26,662,392 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605314,976,920 - 14,979,602 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mgat2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473119,081,110 - 19,082,453 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473119,080,986 - 19,082,887 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mgat2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1782,845,682 - 82,848,296 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mgat2
40 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:79
Count of miRNA genes:55
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000005608
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005608   ⟹   ENSRNOP00000005608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl693,390,786 - 93,395,050 (+)Ensembl
mRatBN7.2 Ensembl687,656,349 - 87,658,177 (+)Ensembl
Rnor_6.0 Ensembl691,476,698 - 91,479,183 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146488   ⟹   ENSRNOP00000108305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl693,390,555 - 93,395,176 (+)Ensembl
RefSeq Acc Id: NM_053604   ⟹   NP_446056
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8693,392,416 - 93,394,905 (+)NCBI
mRatBN7.2687,656,360 - 87,658,849 (+)NCBI
Rnor_6.0691,476,698 - 91,479,187 (+)NCBI
Rnor_5.06100,935,605 - 100,938,094 (+)NCBI
RGSC_v3.4691,137,262 - 91,139,751 (+)RGD
Celera686,155,587 - 86,158,076 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446056 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA86721 (Get FASTA)   NCBI Sequence Viewer  
  AAH81754 (Get FASTA)   NCBI Sequence Viewer  
  EDM03504 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005608
  ENSRNOP00000005608.3
GenBank Protein Q09326 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446056   ⟸   NM_053604
- Peptide Label: precursor
- UniProtKB: Q09326 (UniProtKB/Swiss-Prot),   A6HBU9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005608   ⟸   ENSRNOT00000005608
Ensembl Acc Id: ENSRNOP00000108305   ⟸   ENSRNOT00000146488

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q09326-F1-model_v2 AlphaFold Q09326 1-442 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694632
Promoter ID:EPDNEW_R5156
Type:multiple initiation site
Name:Mgat2_1
Description:mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0691,476,701 - 91,476,761EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620098 AgrOrtholog
BioCyc Gene G2FUF-37258 BioCyc
BioCyc Pathway PWY-7426 [complex N-linked glycan biosynthesis (vertebrates)] BioCyc
BioCyc Pathway Image PWY-7426 BioCyc
Ensembl Genes ENSRNOG00000004234 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005608 ENTREZGENE
  ENSRNOT00000005608.6 UniProtKB/Swiss-Prot
Gene3D-CATH Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7130336 IMAGE-MGC_LOAD
InterPro GlcNAc_II UniProtKB/Swiss-Prot
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot
KEGG Report rno:94273 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93297 IMAGE-MGC_LOAD
NCBI Gene 94273 ENTREZGENE
PANTHER ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE UniProtKB/Swiss-Prot
  PTHR12871 UniProtKB/Swiss-Prot
Pfam MGAT2 UniProtKB/Swiss-Prot
PhenoGen Mgat2 PhenoGen
RatGTEx ENSRNOG00000004234 RatGTEx
Superfamily-SCOP SSF53448 UniProtKB/Swiss-Prot
UniProt A6HBU9 ENTREZGENE, UniProtKB/TrEMBL
  MGAT2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Mgat2  alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase  Mgat2  mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Mgat2  mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase  Mgat2  mannoside acetylglucosaminyltransferase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Mgat2  mannoside acetylglucosaminyltransferase 2    Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase  Name updated 1299863 APPROVED
2005-01-20 Mgat2  Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase    mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase  Name updated 1299863 APPROVED
2002-08-07 Mgat2  mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein 442 amino acids 729011