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Gene: Pdzd2 (PDZ domain containing 2) Rattus norvegicus

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Symbol:

Pdzd2

Name:

PDZ domain containing 2

RGD ID:

619958

Description:

Predicted to be involved in intracellular signal transduction. Located in several cellular components, including apical part of cell; cell-cell junction; and endoplasmic reticulum. Orthologous to human PDZD2 (PDZ domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC102546845; Papin; PDZ domain containing 3; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Pdzk3; plakophilin-related armadillo repeat protein-interacting PDZ protein; uncharacterized LOC102546845; uncharacterized protein LOC102546845

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PDZD2 (PDZ domain containing 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Pdzd2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pdzd2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PDZD2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PDZD2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pdzd2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PDZD2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PDZD2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pdzd2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pdzd2 (PDZ domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	JUND (JunD proto-oncogene, AP-1 transcription factor subunit)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PDZD2 (PDZ domain containing 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pdzd2 (PDZ domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pdzd2 (PDZ domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pdzd2 (PDZ domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	bbg	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	pdzd2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pdzd2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	63,111,650 - 63,497,520 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	63,111,650 - 63,497,478 (-)	Ensembl				GRCr8
mRatBN7.2	2	61,384,614 - 61,770,516 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	61,386,381 - 61,770,524 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	68,516,647 - 68,749,894 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	66,636,963 - 66,872,612 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	61,638,440 - 61,874,092 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	62,399,748 - 62,520,448 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	62,399,748 - 62,634,785 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	82,168,243 - 82,288,609 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	61,828,127 - 61,953,671 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	57,076,815 - 57,309,194 (+)	NCBI		Celera
RGSC_v3.1	2	61,756,359 - 61,864,415 (-)	NCBI
Cytogenetic Map	2	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

lissencephaly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (EXP)

azoxystrobin (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bufotalin (ISO)

C60 fullerene (EXP)

cadmium dichloride (ISO)

calcitriol (ISO)

capsaicin (EXP)

carbon nanotube (ISO)

chlorpyrifos (EXP)

crocidolite asbestos (ISO)

cumene (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

flavonoids (EXP)

folic acid (ISO)

fulvestrant (ISO)

gentamycin (EXP)

glyphosate (EXP)

GW 4064 (ISO)

imidacloprid (EXP)

Indeno[1,2,3-cd]pyrene (ISO)

lipopolysaccharide (ISO)

maneb (ISO)

mercury dichloride (EXP)

methapyrilene (ISO)

methimazole (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

nickel atom (ISO)

nickel dichloride (ISO)

nickel sulfate (ISO)

okadaic acid (ISO)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (EXP)

paraquat (EXP,ISO)

permethrin (EXP)

potassium chromate (ISO)

progesterone (ISO)

rac-lactic acid (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

serpentine asbestos (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

tert-butyl hydroperoxide (ISO)

thiabendazole (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (EXP,ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

intracellular signal transduction (TAS)

Cellular Component

anchoring junction (IEA)

apical part of cell (IDA)

cell-cell junction (IDA)

cytoplasm (IEA,ISO,ISS)

cytosol (IEA,ISO)

endoplasmic reticulum (IDA,IEA)

extracellular region (IDA,IEA)

nucleus (IDA,IEA)

plasma membrane (IEA,ISO)

Molecular Function

protein binding (IPI,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.	Deguchi M, etal., J Biol Chem 2000 Sep 22;275(38):29875-80.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8.	Malik-Hall M, etal., Brain Res Mol Brain Res. 2003 Feb 20;110(2):298-304.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Proteolytic cleavage of PDZD2 generates a secreted peptide containing two PDZ domains.	Yeung ML, etal., EMBO Rep. 2003 Apr;4(4):412-8. Epub 2003 Mar 14.

Additional References at PubMed

PMID:11289102	PMID:12477932	PMID:19607921	PMID:32919022

Genomics

Comparative Map Data

Pdzd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	63,111,650 - 63,497,520 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	63,111,650 - 63,497,478 (-)	Ensembl				GRCr8
mRatBN7.2	2	61,384,614 - 61,770,516 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	61,386,381 - 61,770,524 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	68,516,647 - 68,749,894 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	66,636,963 - 66,872,612 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	61,638,440 - 61,874,092 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	62,399,748 - 62,520,448 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	62,399,748 - 62,634,785 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	82,168,243 - 82,288,609 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	61,828,127 - 61,953,671 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	57,076,815 - 57,309,194 (+)	NCBI		Celera
RGSC_v3.1	2	61,756,359 - 61,864,415 (-)	NCBI
Cytogenetic Map	2	q16	NCBI

PDZD2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	31,639,131 - 32,110,932 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	31,639,121 - 32,110,933 (+)	Ensembl			hg38	GRCh38
GRCh37	5	31,639,238 - 32,111,038 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	31,834,788 - 32,146,795 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	31,675,273 - 32,146,795	NCBI
Celera	5	31,679,264 - 31,992,328 (+)	NCBI		Celera
Cytogenetic Map	5	p13.3	NCBI
HuRef	5	31,766,346 - 32,078,169 (+)	NCBI		HuRef
CHM1_1	5	31,800,063 - 32,112,328 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	31,752,824 - 32,224,543 (+)	NCBI		T2T-CHM13v2.0

Pdzd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	12,359,797 - 12,740,052 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	12,359,797 - 12,740,010 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	12,359,711 - 12,739,968 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	12,359,711 - 12,739,924 (-)	Ensembl			mm10	GRCm38
MGSCv37	15	12,286,809 - 12,522,311 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	12,301,779 - 12,684,649 (-)	NCBI		MGSCv36	mm8
Celera	15	12,136,823 - 12,373,640 (-)	NCBI		Celera
Cytogenetic Map	15	A1	NCBI
cM Map	15	5.9	NCBI

Pdzd2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	17,600,571 - 17,974,914 (+)	Ensembl
ChiLan1.0	NW_004955426	17,600,722 - 17,974,916 (+)	NCBI	ChiLan1.0	ChiLan1.0

PDZD2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	78,199,541 - 78,673,959 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	76,353,166 - 76,827,596 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	78,229,681 - 78,701,213 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	83,611,687 - 84,079,810 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	83,614,460 - 83,921,415 (-)	Ensembl			panPan2	panpan1.1

PDZD2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	75,336,023 - 75,564,980 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	75,338,791 - 75,564,599 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	74,972,179 - 75,330,536 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	75,855,009 - 76,258,330 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	75,855,011 - 76,258,296 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	75,593,378 - 75,951,613 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	75,723,219 - 76,081,215 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	76,251,243 - 76,609,516 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pdzd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	222,362,795 - 222,724,538 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936518	8,646,838 - 9,008,767 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936518	8,647,338 - 8,883,494 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PDZD2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	16	17,940,113 - 18,355,540 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	19,030,168 - 19,172,176 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PDZD2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	30,920,855 - 31,397,578 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	31,177,342 - 31,398,635 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666071	21,144,870 - 21,622,475 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pdzd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	22,411,491 - 22,677,911 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624759	22,408,934 - 22,677,825 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pdzd2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	168,500,001 - 168,731,105 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pdzd2
3832 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	114
Count of miRNA genes:	92
Interacting mature miRNAs:	98
Transcripts:	ENSRNOT00000017937
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578777	Stresp15	Stress response QTL 15	2	0.05	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	2	61556902	106556902	Rat
6480225	Gdil1	Gastrointestinal dilation QTL 1			enteric ganglion morphology trait (VT:0001045)	length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)	2	58388201	77302351	Rat
631500	Bp99	Blood pressure QTL 99	2.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	61051883	104684275	Rat
7387318	Stl32	Serum triglyceride level QTL 32	3.2	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	24117813	69117813	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	36750344	81750344	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
5684996	Bmd85	Bone mineral density QTL 85	4.7	0.024	tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	2	61051541	105724065	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	22038044	67038044	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
152025242	Bw191	Body weight QTL 191	3.62		body mass (VT:0001259)		2	40306867	124537199	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	28889991	73889991	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	41801363	104744824	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
631208	Bw1	Body weight QTL1	5.09		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	2	44904355	85286097	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1300155	Bp174	Blood pressure QTL 174	4.09		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	44537979	112567334	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	159440891	Rat
5684990	Bmd82	Bone mineral density QTL 82	2.8		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	2	61051541	105724065	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	83465677	Rat
1359034	Bp274	Blood pressure QTL 274			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	51266859	96266859	Rat
1558648	Smcn1	Smooth muscle cell number QTL 1		0.039	blood vessel smooth muscle cell quantity (VT:0010525)	aorta smooth muscle cell count per unit vessel length (CMO:0001646)	2	60861391	105861391	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
2306903	Bp336	Blood pressure QTL 336		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	38426449	111295694	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	18227137	63227137	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	36868643	81868643	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	44904355	89904355	Rat
1582246	Cm60	Cardiac mass QTL 60	5.8		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	33269996	78269996	Rat
61438	Cia7	Collagen induced arthritis QTL 7	4.6	0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	2	61051541	143746880	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	73652666	Rat

Markers in Region

D2Mit4

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	61,582,123 - 61,582,311 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	62,594,946 - 62,595,133	NCBI	Rnor6.0
Rnor_5.0	2	82,093,558 - 82,093,745	UniSTS	Rnor5.0
Celera	2	57,114,745 - 57,114,932	UniSTS
RH 2.0 Map	2	346.3	RGD
Cytogenetic Map	2	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	86	59	6	350	186	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103085	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282504	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC095678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF169411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017937 ⟹ ENSRNOP00000017937

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	63,111,650 - 63,325,353 (-)	Ensembl
mRatBN7.2 Ensembl	2	61,386,381 - 61,706,526 (-)	Ensembl
Rnor_6.0 Ensembl	2	62,399,748 - 62,634,785 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093934 ⟹ ENSRNOP00000087015

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	61,620,225 - 61,650,100 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105047 ⟹ ENSRNOP00000079233

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	63,111,650 - 63,497,478 (-)	Ensembl
mRatBN7.2 Ensembl	2	61,386,381 - 61,770,524 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108989 ⟹ ENSRNOP00000093111

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	63,111,650 - 63,497,478 (-)	Ensembl
mRatBN7.2 Ensembl	2	61,386,381 - 61,770,524 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112645 ⟹ ENSRNOP00000091337

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	63,111,650 - 63,497,478 (-)	Ensembl
mRatBN7.2 Ensembl	2	61,386,381 - 61,770,524 (-)	Ensembl

RefSeq Acc Id:

NM_022940 ⟹ NP_075229

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,497,478 (-)	NCBI
mRatBN7.2	2	61,384,615 - 61,770,469 (-)	NCBI
Rnor_6.0	2	62,399,748 - 62,520,448 (-)	NCBI
Rnor_5.0	2	82,168,243 - 82,288,609 (+)	NCBI
RGSC_v3.4	2	61,828,127 - 61,953,671 (-)	RGD
Celera	2	57,076,815 - 57,309,194 (+)	RGD

Sequence:

show sequence

ATGCCCATCACCCAGGACAATGCCTTGCTGCACCTGCCCCTCCTGTACGAGTGGCTGCAGAACA
GCCTGAGGGAGGGTGGGGACAGTCCGGAGCAGCGGCTCTGCCAGGCGGCCATCCAGAAGCTGCA
GGAGTACATCCAACTGAACTTGGCTGTGGATGAGAGTACAGTTCCCCCTGATCACAGTCCCCCG
GAGATGGAGATCTGTACGGTGTATCTCACCAAGCAGCTGGGGGACACTGAGACTGTGGGGCTCA
GTTTTGGCAACATCCCTGTTTTCGGGGACTACGGTGAAAAGCGTCGAGGGGGTAAGAAGAGGAA
AACCCACCAGGGGCCAGTGCTGGACGTGGGCTGCATCTGGGTGACAGAGCTGAGGAAGAACAGC
CCAGCGGGGAAGAGCGGAAAAGTTCGGCTCCGGGATGAGATTCTTTCCCTGAATGGACAGCTGA
TGGTCGGAGTTGATGTCACTGGGGCCAGTTACCTCGCTGAGCAGTGCTGGAATGGCGGCTTCAT
CTACCTGATCATGCTGCGGCGCTTCAAGCAGAAAGCCCACGTGACTTACAATGGCAACAGTGGC
AACAGCTCAGAACCCGGAGAGACACCGACCTTGGAGCTGGGTGACCAGACTTCAAAAAAGGGAA
AAAGAACAAGAAAGTTTGGGGTCATTTCCAGACCCTCTATCAGCAAGACCCCTGAAGACTCCAA
GAGCAGCAGTGGCTGTGACACAGCCGATGATCCCAATTCGGAGTTGGAGAACGGCGCAGACCCC
GAACTTGGAAATGGCCATGCCTTTGAGCTAGAAAATGGCCCGCATTCTCTCAAGGATGTGGCTG
GACCCCATCTGGAGAGGTCAGAAGCGGACAGTGAGGTAGAGCTCAGAGTTCCAAAGACAGAAGC
CCCTCTGAGTGACAGCAATGACAAACGCCGCTTCTCAAAAACTGGGAAGACAGACTTCCAGTCC
AGTGACTGTCTGGCGCGGGAGGAAGTTGGCCGGATATGGAAGATGGAGCTGCTCAAAGAATCAG
ATGGGCTGGGAATTCAGGTTAGTGGAGGCCGAGGATCAAAGCGCTCACCTCACGCTATCGTTGT
CACCCAAGTGAAGGAAGGAGGTGCCGCTCACAGGGATGGCAGGCTGTCCTTAGGAGACGAACTG
CTGGTGATCAATGGTCACTTACTGGTCGGGCTGTCCCACGAGGAAGCTGTGGCCATTCTGCGCT
CAGCCACTGGGATGGTACAGCTGGTAGTGGCCAGCAAGATGCCCGGGTCAGAAGAATCCCAGGA
CGTAGGCAGCTCTGAGGAATCCAAAGGGAACTTGGAAAGTCCCAAACAGGGCAACTGTAAGACG
AAACTCAAGAGCCGACTCTCAGGAGGTGTCCACCGCCTGGAGTCTGTTGAAGAATATAATGAAC
TGATGGTACGAAATGGGGACCCCCGGATCAGGATGCTGGAGGTCTCCCGAGATGGCCGGAAGCA
CTCTCTTCCGCAGCTGCTGGACTCTACTGGGACATCTCAGGAATACCACATCGTGAAGAAGTCT
ACCCGCTCCCTGAGCACCACCCACGTGGAATCACCGTGGAGGCTCATCCGACCTTCTGTCATTT
CCATCATCGGGCTATACAAAGAGAAAGGCAAGGGCCTTGGCTTTAGCATTGCTGGAGGGCGAGA
CTGCATTCGAGGCCAGATGGGAATTTTTGTCAAGACCATTTTCCCAAACGGATCAGCCGCAGAG
GACGGCAGGCTCAAAGAAGGAGATGAAATCCTAGATGTAAATGGAATACCAATCAAGGGCTTGA
CGTTTCAAGAGGCTATTCACACCTTCAAGCAAATCCGAAGTGGGCTGTTTGTCCTCACCGTGCG
CACCAAGCTCCTCAGCCCCAGTCTCACGCCCTGCTCCACTCCCACGCACATGAGCAGATCGAGC
TCCCCAAGCTTCAACACCAACAGTGGGGGAACCCCAGCAGGAGGAGGCCAAGAGGAAGGTGGCT
CTTCATCCCTGGGTCGGAAGGCTCCCGGGCCCAAAGACAGGATTGTCATGGAAGTCACACTCAA
CAAAGAGCCAAGAGTTGGACTGGGCATTGGTGCCTGCTGCTTGGCCTTGGAAAACAGCCCTCCA
GGTATATACATTCACAGCCTTGCCCCTGGATCCGTGGCCAAGATGGAGAGCAACCTGAGCCGGG
GAGACCAAATCCTGGAAGTGAATTCTGTGAACGTGCGTCATGCGGCTTTAAGCAAAGTGCATGC
CATCTTAAGTAAATGTCCCCCAGGGCCTGTTCGCCTGGTCATCGGCCGACACCCTAATCCAAAG
GTCTCGGAGCAGGAAATGGACGAAGTGATAGCACGCAGCACTTACCAGGAAAGCAGAGAAGCCA
ACTCCTCCCCCGGCCTCGGTACCCCCTTGAAGAGCCCCTCTCTGGCCAAAAAGGACTCACTCCT
CTCTGAATCTGAGCTCTCCCAATACTTTGTCCATGATGGCCAGGGCTCCCTGTCAGACTTTGTG
GTGGCTGGCTCTGAGGATGAGGATCACCCTGGAAGTGGATATGAGACCTCGGAGGATGGCAGCC
TGCTTCCTGTCCCCTCAGCTCACAAAGCCAGGGCCAACAGCCTTGTGACCCTTGGAAGCCAGAG
GACTTCTGGGCTCTTACACAAGCAGGTGACAGTTGCCAGGCAAGCCAGTCTCCCCGGAAGCCCC
CAGGTCCTCAGGAACCCTCTTCTCCGCCAGAGGAGGGTGCGTTGCTATGACAGCAATGGTGGCA
GCGATGATGAAGACTTCGATGGTGAAGGGGACTGCATCTCCCTCCCGGGAGTCCTCCCAGGTCC
CGGCAAGCCTCTGGTAGAAGATGACACGAGGCCTGCCTTGACAACCTCTTCCAAAAGTATTGAT
GTGAACAAGCAGGAGGAAAGACTCCAGAAACCACTGGTCAGCAAGGCCTGCTCCGTGCCTCTCC
TCGGCAGCTCGCTGGACTCAGAGCACAGCATCCTCAATGGAGCAGGGGGTACCCCTCCCAAGGT
AGCCAGCCTGCCAGGTTCTGGAGAAACCCCCAAGAATGGGCCCAGAGGCTCTGGGAGAAAAGAA
ATGTCAGGGTCAAGAAGCTCACCAAAGCTGGAATACAGAGTCCCTACAGACACCCAGAGCCCAA
GGAGCCCGGAAAACCATACCTCCCCACCACAGAAGAGTGAAAATCTGGTGTCCAGGCACAAGCC
CGTGGCCAGGATCAGCCCACACTACAAGAGGTCTGATGCAGAGGAGGCCCCAGGTGGAACAGCC
AATGGACCGTGTGCTCAAGACTTGAAAGTCCAGGCGTCTCCCGTGAAAGATCCTGTCACCAGCC
GTCAGCCAGGTGGAACCGCAGAGAAGGAACTTCGGGGAAATCCCACCCCGGGGGACAGCTCTGT
CCCCACCAACTGTGGACCAGCCAGTACCCCATGCCACCCAAACATTGGACTCCCCACAGAGAAC
CCGCAGGGAGCTGCACCAGAGTGCGGGCCACACCCTGGGACTGGATGGGACGGGTCCTCAGAGC
ATCTCTGTTCCCCAGGGAAGAGCAGGGAGGTTCATCCTGACTCCAGCGAGACTCCTACAGTCGC
CGAGCAAGTCCACCAGCCTGAGAGCCTCAGCCAGCCAGTGTCTCCCAGAACCTCAGAGCCTGAG
TCCCAGGGCATATCTAAAATGAAGCCACCCAGTCAGAGATGTGTGTCTCCCAGGGAGAAGGCCT
CAACTCCTCCCGACTCCAGCAGGGCTTGGGCCGCTCCTGGGGACAGCTCTCCTAGCACTAGGAG
AATAGCTGTCCCCATGAGCACAGGAGCAGCACCAGCTACTGCCATCCCACAGGCCTCCCTTGTG
TCCCAGGAAAGGAGCAGAGGCCTCTCAGGTCCCAGCAAGGGCCTGGGAACTAAAGAACTCTGCA
TACCTAAAAGCTTGAAGGACGGTGCTCTGCTCGAAGACACAGCTCCTGCATCTGGAAAGATGTC
ACATGCCAGCAGCCCCTCTGGGCCAGTGGCTACTGAAAGGACCCTGTCAGGAAGCCCAGAGAAC
CCTGTGACAGACATCGACAACTTCATTGAGGAGGCCTCTGAGGCCAGGCTTTCTCAGTCTCCTC
AGAAAGCAGACTGCAGGGCTCACGGGGACACTTTTGAAAGTCAGCCACCAGGTGGAGCTGGGAG
CAGCAGTTCCCACCATGCTCAGATGGTCAGGAGTGACCAGACATCCTCCCCAAGGAAGACTGGA
GGCACAGGCTCGCCCCCACCCCAGCAGTGGGCCCTCCAGCCTTCCGTCCTGGATTCCATCCATC
CTGACAAACATTTGGCTGTGAACAAAACCTTCTTGAACAACTACTCTAGAAATTTTAGCAATTT
CCACGAAGACAGTATTTCCCTTTCAGGCCCGGGCGGCAGTTCAGAGCCGTCGCCCTCATCCATG
TATGGTAACGCTGAAGACTCATCGTCAGACCCTGAGTCTCTTGCTGAAGACCCAGGAGCAGCTG
CCAGGAACAACTGGTCACCTCCTCTGTCTCCTGAGTCCTCCCCTAAAGAAGGTAGCAGTGAGTC
TGAGGACGAGCGAATAGAAATCTGTTCCACAGATGGCTGCCCTGGGACCCCAGTGACTGCCCCT
CCTCCTACCCAGGTTGCACTCTGCCCAGTTCTGCCAGTACAGCAGAGGGCTGTGTGCAAGCCAG
TGGGGGACATCTGTGAGAGAGCCTGCTTCGTGCCAGGAGCCTCACGCACTTCCATCCCGGACTC
TTCTCAGCCATTTTCCTTCCTGGATGTAAGCTCTGAGGAGCCGGAGACATGGGCCAGCATAAAT
GCTTCACAGAACCACATGCCCGTGTGCACAGAAGGAATCATGGACGTCACTAGCACAAGCTCAA
ACATGGGAGACAGCCAGTCTTCCCAAATGACCAGACATTGTCGAAACGCACCATTCGTGCTTGG
GAACCCAGATATGGTAAATGATTTGGGACGTGACCTGCTGGATGAGGGAGCCCCAAAGGAAGGA
GCAGCTGCTGCGAGTGTGATGCGCAGTGTGTTTGCCCTGGGGGCCGAGGGCCCTAAGAACGGAG
AGGCGGTCTTGGCAGATCTACACATTGCCGAGCGCGGCAACCTGGAAGACTTGCTACAGAAACC
AAAAACAATCTCCAGGAGGCCTATCCTGACCTGGTTTAAAGAAATAAATAAAGACAGCCAAGGC
TCACATTTGCGGAGCACATCTGAGAAAGAACAGTCCTCGATGCTGGCTCTGGGTCCTGGCTCGA
AAGCTAACATGGTGAACACCGGCCACAGAAAGGGGGTGACTGTGCCTAAGAGTCCTCCTTCACG
GCAGAAGAGTCAGGAAAATAAAGACCTGCCCCCCAAAAGTCCAGTGGAAACACTAGGTAACTGT
CAGAAACCCAAGTGCAGCCCTAAACTGAAGAGACTAAACAGCAAAGGCAAAGCCAGTCCTGAGG
TACCCGTGGCCATTTCCACTAAGGGCAGCAGGAACGACCACAGGAAGACCTTGCCTTCACCCCA
GGCCTCCCATAAAATGTTTTCTAAGGCAGTGTCACACAGGCTCCACATAGCTGACCAGGAAGAA
CCTAAGAACACTGCTGGGGACACCCCCAAGCCTCCCCAGTGCGTGCCGGAGAGCAAGCCACCCC
AGGCTGCCTTAGGGTCGCTGAGGACCTCCGCATCCGACACAAGCATTAGAACCTTTACTTCGCC
CCTGACCTCCCCCAAGCTTCTCCCTGAGCAGGGTGCAAACAGTAGGTTCCACATGGCTGTCTAC
TTGGAATCTGACACAAGCTGTCCAACCACCTCCAGGTCCCCTAGGAGTGGACCGGAGGGCAAGG
CGCCCCATGCTAACTCTGGGTCAGCGAGTCCCCCAGCATCGAGGGCCAGCCTAGCCTTGGCAGG
GATCAGGCAGAGCAAGCAGTTCACACCGGGCCGAGCAGACTTGTTAGTATCAGAAGCAACCCAG
CCCCAGGGCATCTGTGAGAAAGGAGCTGAAAAAAAGGTTAGTGATCCTCCACAAAGGACAAACC
AGCTAAAAATAGTTGAGATTTCTTCTGAAAGAGTGCCAAAGAATGCATGTGGTGACAGGCCACC
CGAAAGTGACAGAAAGGGAGGGTTCTTGACCCAGAACAACTGTCAGGAGAAGAGTGCAATCAGA
CTCCGGCAGTCGGAGGAATCGTCCCCAGAGCATACACCCTTCCCTCCCTCTCAGGCCTCCCAAG
TGGAACGGGAAATTCGATGGTCTTTCAGCATGGCCAAACCGGCCACCTCTTCCTCCTCCTCCCT
GCAGCTGCCTGCCAAATTGCCAGAGTCCTTCCAGGGCAAATCAAGCCAAATGCCAGCCTCCGTT
GGGGTGCCCAAGAATGGGGTACCCATAGGCCTGGCCGGAGAAGAGAGCCCCTACTTCACACCGA
GGCCAGCCACCAGGACCTATTCCATGCCAGCCCAGTTCTCGAGCCACTTTGGACGAGAAGGTCC
TTCCCCACACAGCCCAAGTCACTCGCCTCAGGACCCGCAGGTCCCTGCGATGGGTGGTAAGCTC
TCTGAGAAGACAGCCAAGGGCGTGACTAATGGACAGGGCGTATATAGTGTGAAGCCTCTGCTGG
AAACATCGAAGAACCTGTCACCAGTGGACGGACGGGATGTCAGTGCAGACCCCGAGACGAGCTG
CCTCATCCCAGACAAGGTCAAAGTCACCAGGAGACAGTACTGCTGTGAGCAGAGTTGGCCCCAT
GAATCTACCTCGTTTTTCTCTGTGAAGCAGAGAATCAAGTCTTTTGAGAACTTGGCCAATTCTG
ACCGGCCCACGGCCAAGTGTGCCACATCCCCGTTCTTATCCGTAAGCTCTAAGCCTCCCATTAA
CAGACGGTCGTCTGGCAGCATCCCTTCAGGGAGCCCCAGCGATATGACCTCGAGGTCGCTGAGG
CGCAGCTTGAGTTCCTGCAGTGAAAGCCAGAGTGAGGCCAGCAGCCTTCTCCCGCAGATGACGA
AGTCCCCCTCCAGCATGACGCTGACTGTCTCCAGGCAGAATCCACCAGACACTAGTAACAAGGG
CCCCAGTCCAGACCCAAAGAAATCACTTGTCCCTGTGGGAATTCCCACCTCCACAGTGAGCCCA
GCCTCACCCAGCAAAAGGAACAAGTCCTCTGTGCGCCATGCCCAGCCCTCTCCAGTATCCCGAT
CCAAGCTCCAGGAGCGGAGAACCTTAAGCATGCCAGACCTGGACAAGCTGTGTAATGGTGAGGA
CGACTCTGCCAGCCCAGGGGCTGTGCTCTTTAAAACCCAGCTGGAGATCACCCCCAGAAGGTCG
AAAGGCTCCCAGGCTACTTCTCCAGCTGGCTCCCCAGCTAGAGGCCATGCAGATTTCAATGGTT
CAACCTTCCTTTCATGTCCTATGAATGGTGGGACCAGAGCCTACACAAAAGGAAACAGCCCTCC
AGCCAGTGAGCCTGCCATAGCCACTGGATCCAGGGAAGAGGGTGAATCTGTGTGGGCCACGCCT
TCTGGGAAAAGCTGGTCGGTGAGTTTGGATCGACTCCTTGCCTCAGTGGGGAACCAGCAGAGAT
TGCAGGGCATTTTATCATTAGTGGGTTCTAAATCCCCCATCCTCACGCTCATTCAGGAAGCGAA
GGCGCAATCAGAGACTAAAGAAGATATCTGCTTCATAGTCTTGAATAAAAAAGAAGGCTCGGGT
CTGGGATTCAGTGTGGCAGGAGGGGCCGACGTGGAGCCAAAATCAGTCATGGTCCACAGGGTGT
TTTCTCAGGGCGTGGCTTCTCAGGAAGGGACTGTGAGCCGAGGGGACTTCCTTCTCTCCGTCAA
TGGCACCTCCTTAGCTGGCTTAGCCCACAGTGAGGTCACGAAGGTTCTGCACCAGGCAGAGCTG
CACAAACACGCCCTCATGATTATCAAGAAAGGGAATGACCAACCCGGGCCCTCCTTCAAGCAGG
AGCCTCCCTCAGCCAATGGGAAAGGCCCTTTCCCCAGAAGGACCTTGCCGCTGGAGCCTGGAGC
TGGGAGAAATGGAGCTGCTCACGATGCGCTGTGTGTTGAAGTGCTGAAAACCTCTGCTGGGCTG
GGATTGAGTCTGGATGGAGGAAAATCGTCTGTATCCGGAGAGGGGCCACTGGTGATTAAAAGGG
TGTACAAAGGCGGTGCGGCCGAACGAGCTGGAACAATAGAAGCGGGTGATGAGATCCTAGCCAT
TAATGGGAAGCCCTTGGTCGGGCTGGTGCACTTCGATGCCTGGAACATCATGAAGTCTGTTCCA
GAAGGGCCCGTGCAGCTAGTGATCAGAAAGCACAGGGATTCGTGA

hide sequence

RefSeq Acc Id:

XM_039103085 ⟹ XP_038959013

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,497,519 (-)	NCBI
mRatBN7.2	2	61,384,614 - 61,770,509 (-)	NCBI

RefSeq Acc Id:

XM_039103086 ⟹ XP_038959014

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,497,519 (-)	NCBI
mRatBN7.2	2	61,384,614 - 61,770,509 (-)	NCBI

RefSeq Acc Id:

XM_039103087 ⟹ XP_038959015

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,376,983 (-)	NCBI
mRatBN7.2	2	61,384,614 - 61,650,068 (-)	NCBI

RefSeq Acc Id:

XM_039103088 ⟹ XP_038959016

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,377,235 (-)	NCBI
mRatBN7.2	2	61,384,614 - 61,650,215 (-)	NCBI

RefSeq Acc Id:

XM_039103090 ⟹ XP_038959018

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,497,520 (-)	NCBI
mRatBN7.2	2	61,384,614 - 61,770,510 (-)	NCBI

RefSeq Acc Id:

XM_039103091 ⟹ XP_038959019

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,497,520 (-)	NCBI
mRatBN7.2	2	61,384,614 - 61,770,510 (-)	NCBI

RefSeq Acc Id:

XM_039103093 ⟹ XP_038959021

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,267,457 (-)	NCBI
mRatBN7.2	2	61,384,614 - 61,529,556 (-)	NCBI

RefSeq Acc Id:

XM_039103094 ⟹ XP_038959022

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,218,493 (-)	NCBI
mRatBN7.2	2	61,384,614 - 61,490,203 (-)	NCBI

RefSeq Acc Id:

XM_063282504 ⟹ XP_063138574

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,111,650 - 63,304,764 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_075229	(Get FASTA)	NCBI Sequence Viewer
	XP_038959013	(Get FASTA)	NCBI Sequence Viewer
	XP_038959014	(Get FASTA)	NCBI Sequence Viewer
	XP_038959015	(Get FASTA)	NCBI Sequence Viewer
	XP_038959016	(Get FASTA)	NCBI Sequence Viewer
	XP_038959018	(Get FASTA)	NCBI Sequence Viewer
	XP_038959019	(Get FASTA)	NCBI Sequence Viewer
	XP_038959021	(Get FASTA)	NCBI Sequence Viewer
	XP_038959022	(Get FASTA)	NCBI Sequence Viewer
	XP_063138574	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD55940	(Get FASTA)	NCBI Sequence Viewer
	EDL82956	(Get FASTA)	NCBI Sequence Viewer
	EDL82957	(Get FASTA)	NCBI Sequence Viewer
	EDL82958	(Get FASTA)	NCBI Sequence Viewer
	EDL82959	(Get FASTA)	NCBI Sequence Viewer
	EDL82960	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017937
	ENSRNOP00000079233
	ENSRNOP00000093111
GenBank Protein	Q9QZR8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_075229 ⟸ NM_022940
- Peptide Label:	isoform 2
- UniProtKB:	A6KJP6 (UniProtKB/TrEMBL), A0A8I6AIY0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPITQDNALLHLPLLYEWLQNSLREGGDSPEQRLCQAAIQKLQEYIQLNLAVDESTVPPDHSPP EMEICTVYLTKQLGDTETVGLSFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNS PAGKSGKVRLRDEILSLNGQLMVGVDVTGASYLAEQCWNGGFIYLIMLRRFKQKAHVTYNGNSG NSSEPGETPTLELGDQTSKKGKRTRKFGVISRPSISKTPEDSKSSSGCDTADDPNSELENGADP ELGNGHAFELENGPHSLKDVAGPHLERSEADSEVELRVPKTEAPLSDSNDKRRFSKTGKTDFQS SDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDEL LVINGHLLVGLSHEEAVAILRSATGMVQLVVASKMPGSEESQDVGSSEESKGNLESPKQGNCKT KLKSRLSGGVHRLESVEEYNELMVRNGDPRIRMLEVSRDGRKHSLPQLLDSTGTSQEYHIVKKS TRSLSTTHVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAE DGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSPSLTPCSTPTHMSRSS SPSFNTNSGGTPAGGGQEEGGSSSLGRKAPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPP GIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHAILSKCPPGPVRLVIGRHPNPK VSEQEMDEVIARSTYQESREANSSPGLGTPLKSPSLAKKDSLLSESELSQYFVHDGQGSLSDFV VAGSEDEDHPGSGYETSEDGSLLPVPSAHKARANSLVTLGSQRTSGLLHKQVTVARQASLPGSP QVLRNPLLRQRRVRCYDSNGGSDDEDFDGEGDCISLPGVLPGPGKPLVEDDTRPALTTSSKSID VNKQEERLQKPLVSKACSVPLLGSSLDSEHSILNGAGGTPPKVASLPGSGETPKNGPRGSGRKE MSGSRSSPKLEYRVPTDTQSPRSPENHTSPPQKSENLVSRHKPVARISPHYKRSDAEEAPGGTA NGPCAQDLKVQASPVKDPVTSRQPGGTAEKELRGNPTPGDSSVPTNCGPASTPCHPNIGLPTEN PQGAAPECGPHPGTGWDGSSEHLCSPGKSREVHPDSSETPTVAEQVHQPESLSQPVSPRTSEPE SQGISKMKPPSQRCVSPREKASTPPDSSRAWAAPGDSSPSTRRIAVPMSTGAAPATAIPQASLV SQERSRGLSGPSKGLGTKELCIPKSLKDGALLEDTAPASGKMSHASSPSGPVATERTLSGSPEN PVTDIDNFIEEASEARLSQSPQKADCRAHGDTFESQPPGGAGSSSSHHAQMVRSDQTSSPRKTG GTGSPPPQQWALQPSVLDSIHPDKHLAVNKTFLNNYSRNFSNFHEDSISLSGPGGSSEPSPSSM YGNAEDSSSDPESLAEDPGAAARNNWSPPLSPESSPKEGSSESEDERIEICSTDGCPGTPVTAP PPTQVALCPVLPVQQRAVCKPVGDICERACFVPGASRTSIPDSSQPFSFLDVSSEEPETWASIN ASQNHMPVCTEGIMDVTSTSSNMGDSQSSQMTRHCRNAPFVLGNPDMVNDLGRDLLDEGAPKEG AAAASVMRSVFALGAEGPKNGEAVLADLHIAERGNLEDLLQKPKTISRRPILTWFKEINKDSQG SHLRSTSEKEQSSMLALGPGSKANMVNTGHRKGVTVPKSPPSRQKSQENKDLPPKSPVETLGNC QKPKCSPKLKRLNSKGKASPEVPVAISTKGSRNDHRKTLPSPQASHKMFSKAVSHRLHIADQEE PKNTAGDTPKPPQCVPESKPPQAALGSLRTSASDTSIRTFTSPLTSPKLLPEQGANSRFHMAVY LESDTSCPTTSRSPRSGPEGKAPHANSGSASPPASRASLALAGIRQSKQFTPGRADLLVSEATQ PQGICEKGAEKKVSDPPQRTNQLKIVEISSERVPKNACGDRPPESDRKGGFLTQNNCQEKSAIR LRQSEESSPEHTPFPPSQASQVEREIRWSFSMAKPATSSSSSLQLPAKLPESFQGKSSQMPASV GVPKNGVPIGLAGEESPYFTPRPATRTYSMPAQFSSHFGREGPSPHSPSHSPQDPQVPAMGGKL SEKTAKGVTNGQGVYSVKPLLETSKNLSPVDGRDVSADPETSCLIPDKVKVTRRQYCCEQSWPH ESTSFFSVKQRIKSFENLANSDRPTAKCATSPFLSVSSKPPINRRSSGSIPSGSPSDMTSRSLR RSLSSCSESQSEASSLLPQMTKSPSSMTLTVSRQNPPDTSNKGPSPDPKKSLVPVGIPTSTVSP ASPSKRNKSSVRHAQPSPVSRSKLQERRTLSMPDLDKLCNGEDDSASPGAVLFKTQLEITPRRS KGSQATSPAGSPARGHADFNGSTFLSCPMNGGTRAYTKGNSPPASEPAIATGSREEGESVWATP SGKSWSVSLDRLLASVGNQQRLQGILSLVGSKSPILTLIQEAKAQSETKEDICFIVLNKKEGSG LGFSVAGGADVEPKSVMVHRVFSQGVASQEGTVSRGDFLLSVNGTSLAGLAHSEVTKVLHQAEL HKHALMIIKKGNDQPGPSFKQEPPSANGKGPFPRRTLPLEPGAGRNGAAHDALCVEVLKTSAGL GLSLDGGKSSVSGEGPLVIKRVYKGGAAERAGTIEAGDEILAINGKPLVGLVHFDAWNIMKSVP EGPVQLVIRKHRDS hide sequence

Ensembl Acc Id:

ENSRNOP00000017937 ⟸ ENSRNOT00000017937

RefSeq Acc Id:	XP_038959019 ⟸ XM_039103091
- Peptide Label:	isoform X3
- UniProtKB:	A6KJP6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959018 ⟸ XM_039103090
- Peptide Label:	isoform X2
- UniProtKB:	A6KJP6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959013 ⟸ XM_039103085
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZMB2 (UniProtKB/TrEMBL), A6KJP6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959014 ⟸ XM_039103086
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZMB2 (UniProtKB/TrEMBL), A6KJP6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959016 ⟸ XM_039103088
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZMB2 (UniProtKB/TrEMBL), A6KJP6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959015 ⟸ XM_039103087
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZMB2 (UniProtKB/TrEMBL), A6KJP6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959021 ⟸ XM_039103093
- Peptide Label:	isoform X4
- UniProtKB:	A6KJQ0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959022 ⟸ XM_039103094
- Peptide Label:	isoform X4
- UniProtKB:	A6KJQ0 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000093111 ⟸ ENSRNOT00000108989

Ensembl Acc Id:

ENSRNOP00000087015 ⟸ ENSRNOT00000093934

Ensembl Acc Id:

ENSRNOP00000079233 ⟸ ENSRNOT00000105047

Ensembl Acc Id:

ENSRNOP00000091337 ⟸ ENSRNOT00000112645

RefSeq Acc Id:	XP_063138574 ⟸ XM_063282504
- Peptide Label:	isoform X4
- UniProtKB:	A6KJQ0 (UniProtKB/TrEMBL)

Protein Domains

PDZ

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:619958	AgrOrtholog
BioCyc Gene	G2FUF-54042	BioCyc
Ensembl Genes	ENSRNOG00000013140	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000017937	ENTREZGENE
	ENSRNOT00000105047	ENTREZGENE
	ENSRNOT00000108989	ENTREZGENE
Gene3D-CATH	2.30.42.10	UniProtKB/Swiss-Prot
InterPro	PDZ	UniProtKB/Swiss-Prot
	PDZ_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:65034	UniProtKB/Swiss-Prot
NCBI Gene	65034	ENTREZGENE
PANTHER	IL16-RELATED	UniProtKB/Swiss-Prot
	PDZ DOMAIN-CONTAINING PROTEIN 2	UniProtKB/Swiss-Prot
Pfam	PDZ	UniProtKB/Swiss-Prot
PhenoGen	Pdzd2	PhenoGen
PROSITE	PDZ	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000013140	RatGTEx
SMART	PDZ	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50156	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZMB2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ABF3_RAT	UniProtKB/TrEMBL
	A0A8I6AIY0	ENTREZGENE, UniProtKB/TrEMBL
	A6KJP6	ENTREZGENE, UniProtKB/TrEMBL
	A6KJQ0	ENTREZGENE, UniProtKB/TrEMBL
	F1M785_RAT	UniProtKB/TrEMBL
	PDZD2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Pdzd2	PDZ domain containing 2	LOC102546845	uncharacterized LOC102546845	Data merged from RGD:7714134	737654	PROVISIONAL
2013-12-18	LOC102546845	uncharacterized LOC102546845			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-02-22	Pdzd2	PDZ domain containing 2	Pdzk3	PDZ domain containing 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Pdzk3	PDZ domain containing 3	Papin	PAPIN	Symbol and Name updated	1299863	APPROVED
2002-08-07	Papin	PAPIN			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains multiple PDZ domains	633698
gene_expression	expressed ubiquitously	633698
gene_physical_interaction	bind s to E-cadherin and beta-catenin	633698

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar