Neo1 (neogenin 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Neo1 (neogenin 1) Rattus norvegicus
Analyze
Symbol: Neo1
Name: neogenin 1
RGD ID: 619837
Description: Predicted to enable several functions, including BMP receptor binding activity; cadherin binding activity; and co-receptor binding activity. Predicted to be involved in cell-cell adhesion; generation of neurons; and trans-synaptic signaling, modulating synaptic transmission. Predicted to act upstream of or within several processes, including multicellular organismal-level iron ion homeostasis; myoblast fusion; and positive regulation of BMP signaling pathway. Located in neuronal cell body. Orthologous to human NEO1 (neogenin 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: neogenin; neogenin homolog 1; neogenin homolog 1 (chicken)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8868,169,711 - 68,322,158 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl868,169,716 - 68,322,152 (-)EnsemblGRCr8
mRatBN7.2859,273,860 - 59,426,486 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl859,275,569 - 59,430,348 (-)EnsemblmRatBN7.2
Rnor_6.0863,649,871 - 63,756,394 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl863,653,266 - 63,750,531 (-)Ensemblrn6Rnor6.0
Rnor_5.0863,417,857 - 63,524,875 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4862,681,481 - 62,789,841 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera858,729,882 - 58,837,487 (-)NCBICelera
RGSC_v3.1862,702,413 - 62,806,918 (-)NCBI
Cytogenetic Map8q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
apigenin  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (EXP)
FR900359  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
phenethyl caffeate  (EXP)
phenobarbital  (ISO)
progesterone  (ISO)
Ptaquiloside  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Deleted in Colorectal Cancer (DCC) encodes a netrin receptor. Keino-Masu K, etal., Cell 1996 Oct 18;87(2):175-85.
4. The repulsive guidance molecule, RGMa, promotes retinal ganglion cell survival in vitro and in vivo. Koeberle PD, etal., Neuroscience. 2010 Aug 11;169(1):495-504. doi: 10.1016/j.neuroscience.2010.04.079. Epub 2010 May 8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. RGMA and neogenin protein expression are influenced by lens injury following optic nerve crush in the rat retina. Schnichels S, etal., Graefes Arch Clin Exp Ophthalmol. 2012 Jan;250(1):39-50. doi: 10.1007/s00417-011-1791-9. Epub 2011 Sep 2.
Additional References at PubMed
PMID:15494733   PMID:15520228   PMID:16075058   PMID:17389603   PMID:17574219   PMID:18326817   PMID:18335997   PMID:18583991   PMID:19564337   PMID:20065295   PMID:26651291   PMID:28623139  


Genomics

Comparative Map Data
Neo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8868,169,711 - 68,322,158 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl868,169,716 - 68,322,152 (-)EnsemblGRCr8
mRatBN7.2859,273,860 - 59,426,486 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl859,275,569 - 59,430,348 (-)EnsemblmRatBN7.2
Rnor_6.0863,649,871 - 63,756,394 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl863,653,266 - 63,750,531 (-)Ensemblrn6Rnor6.0
Rnor_5.0863,417,857 - 63,524,875 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4862,681,481 - 62,789,841 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera858,729,882 - 58,837,487 (-)NCBICelera
RGSC_v3.1862,702,413 - 62,806,918 (-)NCBI
Cytogenetic Map8q24NCBI
NEO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381573,051,692 - 73,305,206 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1573,051,645 - 73,305,205 (+)Ensemblhg38GRCh38
GRCh371573,344,243 - 73,597,546 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361571,131,928 - 71,384,599 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341571,131,927 - 71,382,835NCBI
Celera1550,287,439 - 50,476,112 (+)NCBICelera
Cytogenetic Map15q24.1NCBI
HuRef1550,240,408 - 50,428,957 (+)NCBIHuRef
CHM1_11573,462,785 - 73,715,509 (+)NCBICHM1_1
T2T-CHM13v2.01570,868,937 - 71,122,333 (+)NCBIT2T-CHM13v2.0
Neo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39958,781,962 - 58,943,926 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl958,781,970 - 58,943,724 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38958,874,679 - 59,036,614 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl958,874,687 - 59,036,441 (-)Ensemblmm10GRCm38
MGSCv37958,722,486 - 58,884,248 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36958,674,677 - 58,834,445 (-)NCBIMGSCv36mm8
Celera956,103,366 - 56,261,719 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.81NCBI
Neo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554504,191,168 - 4,375,896 (-)Ensembl
ChiLan1.0NW_0049554504,191,168 - 4,324,997 (-)NCBIChiLan1.0ChiLan1.0
NEO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21662,281,800 - 62,534,799 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11566,446,196 - 66,699,224 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01551,968,238 - 52,221,116 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11570,680,970 - 70,979,687 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1570,789,035 - 70,977,178 (+)EnsemblpanPan2panpan1.1
NEO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13036,387,425 - 36,622,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3036,387,259 - 36,622,154 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3036,323,434 - 36,559,824 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03036,594,775 - 36,830,997 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3036,594,757 - 36,830,992 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13036,547,002 - 36,782,998 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03036,572,984 - 36,808,890 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03036,829,242 - 37,064,354 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Neo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640114,443,410 - 114,671,197 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647132,292,745 - 32,516,624 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647132,345,578 - 32,517,245 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl760,064,994 - 60,300,562 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1760,064,984 - 60,299,892 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2764,688,218 - 64,785,685 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NEO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12610,173,707 - 10,427,732 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2610,176,215 - 10,427,675 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666048131,173,745 - 131,432,558 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Neo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247811,019,603 - 1,227,666 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247811,021,460 - 1,227,680 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Neo1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1852,735,805 - 52,888,883 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Neo1
1155 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:973
Count of miRNA genes:198
Interacting mature miRNAs:232
Transcripts:ENSRNOT00000009312, ENSRNOT00000009496, ENSRNOT00000065980
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85899169791341052Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)84754141992541419Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84961020468373388Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85899169791341052Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85899169791341052Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat

Markers in Region
RH135625  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2859,275,531 - 59,275,792 (+)MAPPERmRatBN7.2
Rnor_6.0863,653,342 - 63,653,602NCBIRnor6.0
Rnor_5.0863,421,328 - 63,421,588UniSTSRnor5.0
RGSC_v3.4862,683,158 - 62,683,418UniSTSRGSC3.4
Celera858,733,353 - 58,733,613UniSTS
Cytogenetic Map8q24UniSTS
RH129374  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2859,275,549 - 59,275,764 (+)MAPPERmRatBN7.2
Rnor_6.0863,653,360 - 63,653,574NCBIRnor6.0
Rnor_5.0863,421,346 - 63,421,560UniSTSRnor5.0
RGSC_v3.4862,683,176 - 62,683,390UniSTSRGSC3.4
Celera858,733,371 - 58,733,585UniSTS
RH 3.4 Map8697.49UniSTS
Cytogenetic Map8q24UniSTS
RH135275  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2859,283,542 - 59,283,722 (+)MAPPERmRatBN7.2
Rnor_6.0863,661,353 - 63,661,532NCBIRnor6.0
Rnor_5.0863,429,339 - 63,429,518UniSTSRnor5.0
RGSC_v3.4862,691,169 - 62,691,348UniSTSRGSC3.4
Celera858,741,364 - 58,741,543UniSTS
RH 3.4 Map8696.59UniSTS
Cytogenetic Map8q24UniSTS
RH140142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2859,275,045 - 59,275,246 (+)MAPPERmRatBN7.2
Rnor_6.0863,652,856 - 63,653,056NCBIRnor6.0
Rnor_5.0863,420,842 - 63,421,042UniSTSRnor5.0
RGSC_v3.4862,682,672 - 62,682,872UniSTSRGSC3.4
Celera858,732,867 - 58,733,067UniSTS
RH 3.4 Map8698.49UniSTS
Cytogenetic Map8q24UniSTS
AU048996  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2859,406,445 - 59,406,737 (+)MAPPERmRatBN7.2
Rnor_6.0863,783,164 - 63,783,455NCBIRnor6.0
Rnor_5.0863,551,150 - 63,551,441UniSTSRnor5.0
RGSC_v3.4862,814,712 - 62,815,003UniSTSRGSC3.4
Celera858,864,250 - 58,864,541UniSTS
Cytogenetic Map8q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 90 59 6 354 190 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001419532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U68726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000009496   ⟹   ENSRNOP00000009496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl868,169,716 - 68,322,152 (-)Ensembl
mRatBN7.2 Ensembl859,275,569 - 59,425,845 (-)Ensembl
Rnor_6.0 Ensembl863,653,266 - 63,750,531 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103674   ⟹   ENSRNOP00000082559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl868,169,716 - 68,322,152 (-)Ensembl
mRatBN7.2 Ensembl859,275,850 - 59,430,348 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117001   ⟹   ENSRNOP00000077374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl868,169,716 - 68,322,152 (-)Ensembl
mRatBN7.2 Ensembl859,275,850 - 59,430,348 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117772   ⟹   ENSRNOP00000080755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl859,275,850 - 59,430,348 (-)Ensembl
RefSeq Acc Id: NM_001419532   ⟹   NP_001406461
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,716 - 68,322,152 (-)NCBI
mRatBN7.2859,273,860 - 59,426,299 (-)NCBI
RefSeq Acc Id: XM_039082413   ⟹   XP_038938341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
mRatBN7.2859,275,633 - 59,426,477 (-)NCBI
RefSeq Acc Id: XM_039082414   ⟹   XP_038938342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
mRatBN7.2859,273,860 - 59,426,479 (-)NCBI
RefSeq Acc Id: XM_039082415   ⟹   XP_038938343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
mRatBN7.2859,273,860 - 59,426,479 (-)NCBI
RefSeq Acc Id: XM_039082416   ⟹   XP_038938344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
mRatBN7.2859,273,860 - 59,426,476 (-)NCBI
RefSeq Acc Id: XM_039082417   ⟹   XP_038938345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
mRatBN7.2859,275,633 - 59,426,476 (-)NCBI
RefSeq Acc Id: XM_039082418   ⟹   XP_038938346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
mRatBN7.2859,273,860 - 59,426,480 (-)NCBI
RefSeq Acc Id: XM_039082419   ⟹   XP_038938347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
mRatBN7.2859,273,860 - 59,426,478 (-)NCBI
RefSeq Acc Id: XM_039082421   ⟹   XP_038938349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
mRatBN7.2859,273,860 - 59,426,486 (-)NCBI
RefSeq Acc Id: XM_063266211   ⟹   XP_063122281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
RefSeq Acc Id: XM_063266212   ⟹   XP_063122282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
RefSeq Acc Id: XM_063266213   ⟹   XP_063122283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
RefSeq Acc Id: XM_063266214   ⟹   XP_063122284
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
RefSeq Acc Id: XM_063266216   ⟹   XP_063122286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8868,169,711 - 68,322,158 (-)NCBI
Ensembl Acc Id: ENSRNOP00000009496   ⟸   ENSRNOT00000009496
RefSeq Acc Id: XP_038938349   ⟸   XM_039082421
- Peptide Label: isoform X13
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038938346   ⟸   XM_039082418
- Peptide Label: isoform X8
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038938343   ⟸   XM_039082415
- Peptide Label: isoform X3
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038938342   ⟸   XM_039082414
- Peptide Label: isoform X2
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038938347   ⟸   XM_039082419
- Peptide Label: isoform X11
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038938344   ⟸   XM_039082416
- Peptide Label: isoform X4
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038938341   ⟸   XM_039082413
- Peptide Label: isoform X1
- UniProtKB: P97603 (UniProtKB/Swiss-Prot),   A0A8I5Y1H5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938345   ⟸   XM_039082417
- Peptide Label: isoform X5
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000077374   ⟸   ENSRNOT00000117001
Ensembl Acc Id: ENSRNOP00000080755   ⟸   ENSRNOT00000117772
Ensembl Acc Id: ENSRNOP00000082559   ⟸   ENSRNOT00000103674
RefSeq Acc Id: NP_001406461   ⟸   NM_001419532
- Peptide Label: precursor
- UniProtKB: P97603 (UniProtKB/Swiss-Prot),   A0A8I5ZV53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122282   ⟸   XM_063266212
- Peptide Label: isoform X7
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063122281   ⟸   XM_063266211
- Peptide Label: isoform X6
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063122286   ⟸   XM_063266216
- Peptide Label: isoform X12
- UniProtKB: P97603 (UniProtKB/Swiss-Prot),   A0A8I5ZQS8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122284   ⟸   XM_063266214
- Peptide Label: isoform X10
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063122283   ⟸   XM_063266213
- Peptide Label: isoform X9
- UniProtKB: P97603 (UniProtKB/Swiss-Prot)
Protein Domains
Fibronectin type-III   Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97603-F1-model_v2 AlphaFold P97603 1-1377 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619837 AgrOrtholog
BioCyc Gene G2FUF-30252 BioCyc
Ensembl Genes ENSRNOG00000006490 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000009496 ENTREZGENE
  ENSRNOT00000103674 ENTREZGENE
  ENSRNOT00000117001 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Neogenin_C UniProtKB/Swiss-Prot
NCBI Gene 81735 ENTREZGENE
PANTHER PROTEIN SIDEKICK UniProtKB/Swiss-Prot
  PTHR44170:SF14 UniProtKB/Swiss-Prot
Pfam fn3 UniProtKB/Swiss-Prot
  I-set UniProtKB/Swiss-Prot
  Ig_2 UniProtKB/Swiss-Prot
  Neogenin_C UniProtKB/Swiss-Prot
PhenoGen Neo1 PhenoGen
PRINTS FNTYPEIII UniProtKB/Swiss-Prot
PROSITE FN3 UniProtKB/Swiss-Prot
  IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000006490 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
  IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
UniProt A0A8I5Y1H5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQS8 ENTREZGENE
  A0A8I5ZV53 ENTREZGENE, UniProtKB/TrEMBL
  A6J515_RAT UniProtKB/TrEMBL
  A6J516_RAT UniProtKB/TrEMBL
  F1M0Z6_RAT UniProtKB/TrEMBL
  NEO1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Neo1  neogenin 1  Neo1  neogenin homolog 1 (chicken)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Neo1  neogenin homolog 1 (chicken)  Neo1  neogenin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Neo1  neogenin      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Neo1  neogenin      Symbol and Name status set to provisional 70820 PROVISIONAL