Ptprk (protein tyrosine phosphatase, receptor type, K) - Rat Genome Database

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Gene: Ptprk (protein tyrosine phosphatase, receptor type, K) Rattus norvegicus
Analyze
Symbol: Ptprk
Name: protein tyrosine phosphatase, receptor type, K
RGD ID: 619706
Description: Predicted to enable several functions, including beta-catenin binding activity; gamma-catenin binding activity; and protein tyrosine phosphatase activity. Involved in T cell differentiation; cell adhesion; and neuron projection development. Predicted to be located in several cellular components, including leading edge membrane; neuronal cell body; and photoreceptor outer segment. Orthologous to human PTPRK (protein tyrosine phosphatase receptor type K); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: protein tyrosine phosphatase, receptor type, K, extracellular region; receptor-like protein tyrosine phosphatase kappa extracellular region (RPTPK); receptor-type tyrosine-protein phosphatase kappa; Rptpk
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Is Marker For: Strains:   WKAH.LEC-Ptprkthid/Tj
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8118,557,091 - 19,056,297 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl118,558,365 - 19,056,107 (-)EnsemblGRCr8
mRatBN7.2116,738,896 - 17,236,687 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl116,850,576 - 17,103,605 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx116,509,656 - 17,007,437 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0122,511,543 - 23,009,344 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0116,710,255 - 17,208,405 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0117,445,052 - 18,058,266 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl117,446,417 - 18,058,055 (-)Ensemblrn6Rnor6.0
Rnor_5.0118,602,550 - 18,714,238 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0119,260,651 - 19,574,958 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4117,328,563 - 17,752,200 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera115,151,226 - 15,646,653 (-)NCBICelera
RGSC_v3.1117,332,345 - 17,752,187 (-)NCBI
Cytogenetic Map1p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
fenvalerate  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
folpet  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
gentamycin  (EXP)
GW 7647  (EXP,ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mifepristone  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel dichloride  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
parathion  (ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phenylephrine  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
sunitinib  (ISO)
Tanshinone I  (ISO)
taurine  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP,ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. A soluble version of the receptor-like protein tyrosine phosphatase kappa stimulates neurite outgrowth via a Grb2/MEK1-dependent signaling cascade. Drosopoulos NE, etal., Mol Cell Neurosci 1999 Jun;13(6):441-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Maturational arrest of thymocyte development is caused by a deletion in the receptor-like protein tyrosine phosphatase kappa gene in LEC rats. Kose H, etal., Genomics. 2007 Jun;89(6):673-7. doi: 10.1016/j.ygeno.2007.03.001. Epub 2007 Apr 16.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8474452   PMID:8663237   PMID:15899872   PMID:16263724   PMID:16849327   PMID:17909891   PMID:18276111   PMID:18308476   PMID:20203423  


Genomics

Comparative Map Data
Ptprk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8118,557,091 - 19,056,297 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl118,558,365 - 19,056,107 (-)EnsemblGRCr8
mRatBN7.2116,738,896 - 17,236,687 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl116,850,576 - 17,103,605 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx116,509,656 - 17,007,437 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0122,511,543 - 23,009,344 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0116,710,255 - 17,208,405 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0117,445,052 - 18,058,266 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl117,446,417 - 18,058,055 (-)Ensemblrn6Rnor6.0
Rnor_5.0118,602,550 - 18,714,238 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0119,260,651 - 19,574,958 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4117,328,563 - 17,752,200 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera115,151,226 - 15,646,653 (-)NCBICelera
RGSC_v3.1117,332,345 - 17,752,187 (-)NCBI
Cytogenetic Map1p12NCBI
PTPRK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386127,968,785 - 128,520,599 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6127,968,780 - 128,520,619 (-)Ensemblhg38GRCh38
GRCh376128,289,930 - 128,841,744 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366128,331,625 - 128,883,416 (-)NCBIBuild 36Build 36hg18NCBI36
Build 346128,331,624 - 128,883,416NCBI
Celera6129,032,183 - 129,588,206 (-)NCBICelera
Cytogenetic Map6q22.33NCBI
HuRef6125,866,873 - 126,423,070 (-)NCBIHuRef
CHM1_16128,554,184 - 129,106,304 (-)NCBICHM1_1
T2T-CHM13v2.06129,157,761 - 129,713,738 (-)NCBIT2T-CHM13v2.0
Ptprk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391027,950,406 - 28,473,393 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1027,950,816 - 28,473,393 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381028,074,820 - 28,597,397 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1028,074,820 - 28,597,397 (+)Ensemblmm10GRCm38
MGSCv371027,794,626 - 28,317,203 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361027,764,236 - 28,285,656 (+)NCBIMGSCv36mm8
Celera1028,989,399 - 29,512,323 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1015.06NCBI
Ptprk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554368,975,554 - 9,380,971 (-)Ensembl
ChiLan1.0NW_0049554368,975,742 - 9,371,608 (-)NCBIChiLan1.0ChiLan1.0
PTPRK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25147,959,554 - 148,521,864 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16145,868,253 - 146,426,592 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06125,753,656 - 126,312,124 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16129,864,573 - 130,421,909 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6129,864,573 - 130,421,644 (-)EnsemblpanPan2panpan1.1
PTPRK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,596,659 - 67,022,631 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl166,597,563 - 67,124,540 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha167,338,192 - 67,890,229 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0166,803,917 - 67,357,303 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,804,293 - 67,357,612 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,734,112 - 67,280,517 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,516,991 - 67,063,682 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0167,160,079 - 67,706,400 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ptprk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946116,735,448 - 117,236,710 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366391,278,808 - 1,682,279 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366391,279,795 - 1,683,944 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl134,693,368 - 35,258,699 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1134,693,363 - 35,258,699 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2138,212,995 - 38,839,894 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11345,062,273 - 45,619,939 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1345,062,342 - 45,619,929 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604017,264,251 - 17,849,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247532,357,680 - 2,877,981 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247532,357,800 - 2,878,176 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ptprk
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12214,173,772 - 214,669,401 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ptprk
4571 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:47
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000020988
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1529322934184556Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1126564886Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1529322934184556Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1126564886Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1128483164Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1529322934184556Rat

Markers in Region
RH144364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2116,793,378 - 16,793,585 (+)MAPPERmRatBN7.2
Rnor_6.0117,500,945 - 17,501,151NCBIRnor6.0
Rnor_5.0118,656,084 - 18,656,290UniSTSRnor5.0
Celera115,205,463 - 15,205,669UniSTS
RH 3.4 Map1167.0UniSTS
Cytogenetic Map1p12UniSTS
AU028812  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8118,986,113 - 18,986,212 (+)Marker Load Pipeline
mRatBN7.2117,166,684 - 17,166,783 (+)MAPPERmRatBN7.2
Rnor_6.0117,975,973 - 17,976,071NCBIRnor6.0
Rnor_5.0119,495,320 - 19,495,418UniSTSRnor5.0
RGSC_v3.4117,681,690 - 17,681,788UniSTSRGSC3.4
Celera115,576,743 - 15,576,833UniSTS
Cytogenetic Map1p12UniSTS


Related Rat Strains
The following Strains have been annotated to Ptprk
WKAH.LEC-Ptprkthid/Tj    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 87 59 6 351 187 11 138 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001029902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB288087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB288088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB297790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF142480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BR000415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000020988   ⟹   ENSRNOP00000020988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl118,670,036 - 18,923,044 (-)Ensembl
mRatBN7.2 Ensembl116,850,576 - 17,103,605 (-)Ensembl
Rnor_6.0 Ensembl117,446,417 - 18,058,055 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000121569   ⟹   ENSRNOP00000107475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl118,558,365 - 19,056,107 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000121655   ⟹   ENSRNOP00000100835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl118,558,365 - 19,056,107 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000132092   ⟹   ENSRNOP00000104699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl118,558,365 - 19,056,107 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000150254   ⟹   ENSRNOP00000105620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl118,558,365 - 19,056,107 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000151000   ⟹   ENSRNOP00000099423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl118,558,365 - 19,056,107 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156515   ⟹   ENSRNOP00000108431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl118,558,365 - 19,056,107 (-)Ensembl
RefSeq Acc Id: NM_001029902   ⟹   NP_001025073
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,558,456 - 19,056,108 (-)NCBI
mRatBN7.2116,738,896 - 17,236,687 (-)NCBI
Rnor_6.0117,446,417 - 18,058,055 (-)NCBI
Rnor_5.0118,602,550 - 18,714,238 (-)NCBI
Rnor_5.0119,260,651 - 19,574,958 (-)NCBI
RGSC_v3.4117,328,563 - 17,752,200 (-)RGD
Celera115,151,226 - 15,646,653 (-)RGD
Sequence:
RefSeq Acc Id: XM_063265867   ⟹   XP_063121937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265868   ⟹   XP_063121938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265871   ⟹   XP_063121941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265872   ⟹   XP_063121942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265875   ⟹   XP_063121945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265877   ⟹   XP_063121947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265880   ⟹   XP_063121950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265884   ⟹   XP_063121954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265887   ⟹   XP_063121957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265889   ⟹   XP_063121959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265898   ⟹   XP_063121968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265905   ⟹   XP_063121975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265906   ⟹   XP_063121976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265907   ⟹   XP_063121977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265913   ⟹   XP_063121983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265919   ⟹   XP_063121989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265927   ⟹   XP_063121997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265936   ⟹   XP_063122006
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,585,586 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265939   ⟹   XP_063122009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,585,586 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265943   ⟹   XP_063122013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,585,586 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265944   ⟹   XP_063122014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,612,812 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265945   ⟹   XP_063122015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
RefSeq Acc Id: XM_063265948   ⟹   XP_063122018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8118,557,091 - 19,056,297 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001025073 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121937 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121938 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121941 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121942 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121945 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121947 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121950 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121954 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121957 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121959 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121968 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121975 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121976 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121977 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121983 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121989 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121997 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122006 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122009 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122013 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122014 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122015 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122018 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD31888 (Get FASTA)   NCBI Sequence Viewer  
  BAF62688 (Get FASTA)   NCBI Sequence Viewer  
  BAF62689 (Get FASTA)   NCBI Sequence Viewer  
  BAF80066 (Get FASTA)   NCBI Sequence Viewer  
  EDL93822 (Get FASTA)   NCBI Sequence Viewer  
  EDL93823 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020988.8
  ENSRNOP00000099423
  ENSRNOP00000099423.1
  ENSRNOP00000100835
  ENSRNOP00000100835.1
  ENSRNOP00000104699
  ENSRNOP00000104699.1
  ENSRNOP00000105620
  ENSRNOP00000105620.1
  ENSRNOP00000107475
  ENSRNOP00000107475.1
  ENSRNOP00000108431
  ENSRNOP00000108431.1
GenBank Protein FAA00326 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001025073   ⟸   NM_001029902
- Peptide Label: precursor
- UniProtKB: A5I9F0 (UniProtKB/TrEMBL),   F1LPL4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020988   ⟸   ENSRNOT00000020988
RefSeq Acc Id: XP_063121997   ⟸   XM_063265927
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063121983   ⟸   XM_063265913
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063121975   ⟸   XM_063265905
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063122018   ⟸   XM_063265948
- Peptide Label: isoform X23
RefSeq Acc Id: XP_063121950   ⟸   XM_063265880
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063121938   ⟸   XM_063265868
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063121989   ⟸   XM_063265919
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063121977   ⟸   XM_063265907
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063121976   ⟸   XM_063265906
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063121968   ⟸   XM_063265898
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063121957   ⟸   XM_063265887
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063122015   ⟸   XM_063265945
- Peptide Label: isoform X22
RefSeq Acc Id: XP_063121947   ⟸   XM_063265877
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063121959   ⟸   XM_063265889
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063121954   ⟸   XM_063265884
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063121945   ⟸   XM_063265875
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063121941   ⟸   XM_063265871
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063121942   ⟸   XM_063265872
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063121937   ⟸   XM_063265867
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063122013   ⟸   XM_063265943
- Peptide Label: isoform X20
- UniProtKB: A6JPF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122009   ⟸   XM_063265939
- Peptide Label: isoform X19
- UniProtKB: A6JPF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122006   ⟸   XM_063265936
- Peptide Label: isoform X18
- UniProtKB: A6JPF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122014   ⟸   XM_063265944
- Peptide Label: isoform X21
Ensembl Acc Id: ENSRNOP00000104699   ⟸   ENSRNOT00000132092
Ensembl Acc Id: ENSRNOP00000107475   ⟸   ENSRNOT00000121569
Ensembl Acc Id: ENSRNOP00000100835   ⟸   ENSRNOT00000121655
Ensembl Acc Id: ENSRNOP00000105620   ⟸   ENSRNOT00000150254
Ensembl Acc Id: ENSRNOP00000108431   ⟸   ENSRNOT00000156515
Ensembl Acc Id: ENSRNOP00000099423   ⟸   ENSRNOT00000151000
Protein Domains
Fibronectin type-III   Ig-like   MAM   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A5I9F0-F1-model_v2 AlphaFold A5I9F0 1-1439 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619706 AgrOrtholog
BioCyc Gene G2FUF-62171 BioCyc
Ensembl Genes ENSRNOG00000047605 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020988.9 UniProtKB/TrEMBL
  ENSRNOT00000121569 ENTREZGENE
  ENSRNOT00000121569.1 UniProtKB/TrEMBL
  ENSRNOT00000121655 ENTREZGENE
  ENSRNOT00000121655.1 UniProtKB/TrEMBL
  ENSRNOT00000132092 ENTREZGENE
  ENSRNOT00000132092.1 UniProtKB/TrEMBL
  ENSRNOT00000150254 ENTREZGENE
  ENSRNOT00000150254.1 UniProtKB/TrEMBL
  ENSRNOT00000151000 ENTREZGENE
  ENSRNOT00000151000.1 UniProtKB/TrEMBL
  ENSRNOT00000156515 ENTREZGENE
  ENSRNOT00000156515.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro ConA-like_dom UniProtKB/TrEMBL
  Fn3_PTPRU UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  FN_III UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  MAM_dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Protein-Tyr_Phosphatase UniProtKB/TrEMBL
  R-tyr_protein_phosphatases UniProtKB/TrEMBL
  Tyr/Dual-sp_Pase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_rcpt/non-rcpt UniProtKB/TrEMBL
KEGG Report rno:360302 UniProtKB/TrEMBL
NCBI Gene Ptprk ENTREZGENE
PANTHER PROTEIN-TYROSINE-PHOSPHATASE UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  Fn3_PTPRU UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PhenoGen Ptprk PhenoGen
PRINTS MAMDOMAIN UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  MAM_1 UniProtKB/TrEMBL
  MAM_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047605 RatGTEx
SMART FN3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
  FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A8J8XMU1_RAT UniProtKB/TrEMBL
  A0ABK0LF19_RAT UniProtKB/TrEMBL
  A0ABK0LG64_RAT UniProtKB/TrEMBL
  A0ABK0LL87_RAT UniProtKB/TrEMBL
  A0ABK0LP24_RAT UniProtKB/TrEMBL
  A0ABK0LT58_RAT UniProtKB/TrEMBL
  A0ABK0LVG5_RAT UniProtKB/TrEMBL
  A5HV09_RAT UniProtKB/TrEMBL
  A5HV10_RAT UniProtKB/TrEMBL
  A5I9F0 ENTREZGENE, UniProtKB/TrEMBL
  A6JPF0 ENTREZGENE, UniProtKB/TrEMBL
  A6JPF1_RAT UniProtKB/TrEMBL
  F1LPL4 ENTREZGENE
UniProt Secondary F1LPL4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Ptprk  protein tyrosine phosphatase, receptor type, K  Ptprk  protein tyrosine phosphatase, receptor type, K, extracellular region  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Ptprk  protein tyrosine phosphatase, receptor type, K, extracellular region  Rptpk  receptor-like protein tyrosine phosphatase kappa extracellular region (RPTPK)  Symbol and Name updated 1299863 APPROVED
2002-08-07 Rptpk  receptor-like protein tyrosine phosphatase kappa extracellular region (RPTPK)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains extracellular domain can support homophilic adhesion 634006