Ptma (prothymosin alpha) - Rat Genome Database

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Gene: Ptma (prothymosin alpha) Rattus norvegicus
Analyze
Symbol: Ptma
Name: prothymosin alpha
RGD ID: 61829
Description: Predicted to enable DNA-binding transcription factor binding activity; histone binding activity; and histone chaperone activity. Involved in positive regulation of NF-kappaB transcription factor activity and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human PTMA (prothymosin alpha); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha-prothymosin; prothymosin-alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8994,624,194 - 94,628,276 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl994,624,196 - 94,628,276 (+)EnsemblGRCr8
mRatBN7.2987,176,251 - 87,180,333 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl987,176,230 - 87,180,333 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx995,593,165 - 95,597,249 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09100,722,287 - 100,726,371 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0999,104,565 - 99,108,647 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0993,545,396 - 93,549,436 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl993,545,396 - 93,549,436 (+)Ensemblrn6Rnor6.0
Rnor_5.0993,273,333 - 93,277,373 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4985,291,203 - 85,295,242 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera984,591,345 - 84,595,385 (+)NCBICelera
RGSC_v3.1985,474,621 - 85,478,661 (+)NCBI
Cytogenetic Map9q35NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2-hydroxypropanoic acid  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bromobenzene  (EXP)
buspirone  (EXP)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroform  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (EXP)
DDE  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
fipronil  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fructose  (EXP)
furfural  (ISO)
genistein  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
glutathione  (ISO)
haloperidol  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
N-nitrosodiethylamine  (EXP)
naloxone  (EXP)
nickel sulfate  (ISO)
nitrates  (ISO)
O-acetyl-L-carnitine  (EXP)
ochratoxin A  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (EXP)
quinidine  (EXP)
rac-lactic acid  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
tetracycline  (EXP)
tetraphene  (ISO)
theophylline  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triadimefon  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
trovafloxacin  (EXP)
tubocurarine  (ISO)
uranium atom  (ISO)
ursodeoxycholic acid  (EXP)
valproic acid  (ISO)
vandetanib  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Tissue-specific and differential expression of prothymosin alpha gene during rat development. Dosil M, etal., FEBS Lett 1990 Sep 3;269(2):373-6.
2. Prothymosin alpha and parathymosin: amino acid sequences deduced from the cloned rat spleen cDNAs. Frangou-Lazaridis M, etal., Arch Biochem Biophys 1988 Jun;263(2):305-10.
3. An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-myc. Gaubatz S, etal., Mol Cell Biol 1994 Jun;14(6):3853-62.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Jiang X, etal., Science 2003 Jan 10;299(5604):223-6.
7. Prothymosin alpha interacts with the CREB-binding protein and potentiates transcription. Karetsou Z, etal., EMBO Rep. 2002 Apr;3(4):361-6. Epub 2002 Mar 15.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:1989881   PMID:2226321   PMID:2269362   PMID:3855555   PMID:8485135   PMID:15489334   PMID:16478804   PMID:16845491   PMID:20432433   PMID:20434447   PMID:20467443   PMID:23278181  
PMID:23359453   PMID:23376485   PMID:25002582  


Genomics

Comparative Map Data
Ptma
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8994,624,194 - 94,628,276 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl994,624,196 - 94,628,276 (+)EnsemblGRCr8
mRatBN7.2987,176,251 - 87,180,333 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl987,176,230 - 87,180,333 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx995,593,165 - 95,597,249 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09100,722,287 - 100,726,371 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0999,104,565 - 99,108,647 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0993,545,396 - 93,549,436 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl993,545,396 - 93,549,436 (+)Ensemblrn6Rnor6.0
Rnor_5.0993,273,333 - 93,277,373 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4985,291,203 - 85,295,242 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera984,591,345 - 84,595,385 (+)NCBICelera
RGSC_v3.1985,474,621 - 85,478,661 (+)NCBI
Cytogenetic Map9q35NCBI
PTMA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,708,525 - 231,713,551 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,706,895 - 231,713,552 (+)Ensemblhg38GRCh38
GRCh372232,573,235 - 232,578,261 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362232,281,479 - 232,286,495 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342232,398,740 - 232,403,754NCBI
Celera2226,349,751 - 226,354,767 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2224,415,419 - 224,421,126 (+)NCBIHuRef
CHM1_12232,579,058 - 232,584,074 (+)NCBICHM1_1
T2T-CHM13v2.02232,193,095 - 232,198,121 (+)NCBIT2T-CHM13v2.0
Ptma
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,454,442 - 86,458,434 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,454,448 - 86,458,434 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38186,526,557 - 86,530,712 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,526,726 - 86,530,712 (+)Ensemblmm10GRCm38
MGSCv37188,423,311 - 88,427,273 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36188,357,907 - 88,361,869 (+)NCBIMGSCv36mm8
Celera189,496,434 - 89,500,314 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.96NCBI
Ptma
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554534,036,503 - 4,037,788 (-)NCBIChiLan1.0ChiLan1.0
PTMA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213134,329,362 - 134,335,272 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B134,344,327 - 134,350,223 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B118,959,382 - 118,964,364 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B237,746,118 - 237,750,806 (+)NCBIPanPan1.1PanPan1.1panPan2
PTMA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12543,563,145 - 43,567,987 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2543,562,395 - 43,675,699 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2544,056,313 - 44,061,150 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02543,818,611 - 43,823,463 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2543,817,860 - 43,823,463 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12543,746,908 - 43,751,731 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02543,590,250 - 43,595,085 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02543,745,404 - 43,750,240 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ptma
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303185,679,168 - 185,685,998 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365255,254,430 - 5,258,105 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365255,253,723 - 5,258,300 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTMA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15132,355,655 - 132,361,435 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115132,353,763 - 132,361,442 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PTMA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110117,721,097 - 117,722,065 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604081,712,038 - 81,716,974 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptma
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248434,728,963 - 4,732,839 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248434,728,963 - 4,732,659 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ptma
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14158,661,484 - 158,665,570 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ptma
50 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:156
Count of miRNA genes:114
Interacting mature miRNAs:119
Transcripts:ENSRNOT00000025093, ENSRNOT00000051368
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)986720043110356905Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)985262459109044727Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat

Markers in Region
BE099527  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2987,177,268 - 87,177,431 (+)MAPPERmRatBN7.2
Rnor_6.0993,546,378 - 93,546,540NCBIRnor6.0
Rnor_5.0993,274,315 - 93,274,477UniSTSRnor5.0
RGSC_v3.4985,292,185 - 85,292,347UniSTSRGSC3.4
Celera984,592,327 - 84,592,489UniSTS
Cytogenetic Map9q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 61 134 57 60 41 86 41 298 168 11 125 71 73 19 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_021740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC112440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC061972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M20035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M33024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M60665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M86564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000025093   ⟹   ENSRNOP00000025093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl994,625,841 - 94,628,271 (+)Ensembl
mRatBN7.2 Ensembl987,176,252 - 87,180,333 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094457   ⟹   ENSRNOP00000095675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl994,624,199 - 94,628,271 (+)Ensembl
mRatBN7.2 Ensembl987,176,230 - 87,180,333 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102204   ⟹   ENSRNOP00000086906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl994,627,216 - 94,628,276 (+)Ensembl
mRatBN7.2 Ensembl987,177,984 - 87,180,312 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108532   ⟹   ENSRNOP00000082211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl994,624,196 - 94,628,271 (+)Ensembl
mRatBN7.2 Ensembl987,177,945 - 87,180,312 (+)Ensembl
RefSeq Acc Id: NM_021740   ⟹   NP_068508
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8994,624,194 - 94,628,276 (+)NCBI
mRatBN7.2987,176,251 - 87,180,333 (+)NCBI
Rnor_6.0993,545,396 - 93,549,436 (+)NCBI
Rnor_5.0993,273,333 - 93,277,373 (+)NCBI
RGSC_v3.4985,291,203 - 85,295,242 (+)RGD
Celera984,591,345 - 84,595,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063266809   ⟹   XP_063122879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8994,624,477 - 94,628,276 (+)NCBI
RefSeq Acc Id: NP_068508   ⟸   NM_021740
- UniProtKB: Q569C8 (UniProtKB/Swiss-Prot),   P06302 (UniProtKB/Swiss-Prot),   A6JWI4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025093   ⟸   ENSRNOT00000025093
Ensembl Acc Id: ENSRNOP00000082211   ⟸   ENSRNOT00000108532
Ensembl Acc Id: ENSRNOP00000086906   ⟸   ENSRNOT00000102204
Ensembl Acc Id: ENSRNOP00000095675   ⟸   ENSRNOT00000094457
RefSeq Acc Id: XP_063122879   ⟸   XM_063266809
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G747 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06302-F1-model_v2 AlphaFold P06302 1-112 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696824
Promoter ID:EPDNEW_R7349
Type:multiple initiation site
Name:LOC100359583_1
Description:hypothetical protein LOC100359583
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0993,545,365 - 93,545,425EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61829 AgrOrtholog
BioCyc Gene G2FUF-26869 BioCyc
Ensembl Genes ENSRNOG00000018584 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000025093 ENTREZGENE
  ENSRNOT00000108532 ENTREZGENE
IMAGE_CLONE IMAGE:5623463 IMAGE-MGC_LOAD
  IMAGE:7307282 IMAGE-MGC_LOAD
InterPro Pro/parathymosin UniProtKB/Swiss-Prot
KEGG Report rno:29222 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108698 IMAGE-MGC_LOAD
  MGC:72468 IMAGE-MGC_LOAD
NCBI Gene 29222 ENTREZGENE
PANTHER PROTHYMOSIN ALPHA UniProtKB/Swiss-Prot
  PTHR22745 UniProtKB/Swiss-Prot
Pfam Prothymosin UniProtKB/Swiss-Prot
PhenoGen Ptma PhenoGen
RatGTEx ENSRNOG00000018584 RatGTEx
TIGR TC203976
UniProt A0A8I6AP82_RAT UniProtKB/TrEMBL
  A0A8I6G747 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GFG4_RAT UniProtKB/TrEMBL
  A6JWI4 ENTREZGENE, UniProtKB/TrEMBL
  P06302 ENTREZGENE, UniProtKB/Swiss-Prot
  Q569C8 ENTREZGENE
UniProt Secondary Q569C8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ptma  prothymosin alpha      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_homology has a region with similarity to a 12 amino acid segment of the HTLV-IIIB p17 protein 61720