Vipr2 (vasoactive intestinal peptide receptor 2) - Rat Genome Database

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Gene: Vipr2 (vasoactive intestinal peptide receptor 2) Rattus norvegicus
Analyze
Symbol: Vipr2
Name: vasoactive intestinal peptide receptor 2
RGD ID: 3962
Description: Enables vasoactive intestinal polypeptide receptor activity. Involved in activation of adenylate cyclase activity and negative regulation of smooth muscle cell proliferation. Predicted to be active in plasma membrane. Orthologous to human VIPR2 (vasoactive intestinal peptide receptor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: PACAP type III receptor; PACAP-R-3; PACAP-R3; pituitary adenylate cyclase-activating polypeptide type III receptor; vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP-R-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86143,139,672 - 143,213,609 (+)NCBIGRCr8
mRatBN7.26136,996,664 - 137,070,599 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6137,001,511 - 137,070,597 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6140,436,878 - 140,505,908 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06137,061,345 - 137,130,423 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06137,609,234 - 137,678,261 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06143,932,960 - 144,009,476 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6143,938,040 - 144,008,072 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06152,871,204 - 152,945,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,347,748 - 143,416,680 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16143,353,934 - 143,422,867 (+)NCBI
Celera6134,667,982 - 134,736,986 (+)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
plasma membrane  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The VIP2 receptor: molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide. Lutz EM, etal., FEBS Lett 1993 Nov 8;334(1):3-8.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Role of VPAC1 and VPAC2 in VIP mediated inhibition of rat pulmonary artery and aortic smooth muscle cell proliferation. St Hilaire RC, etal., Peptides. 2010 Aug;31(8):1517-22. Epub 2010 May 7.
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
10. Two receptors for vasoactive intestinal polypeptide with similar specificity and complementary distributions. Usdin TB, etal., Endocrinology 1994 Dec;135(6):2662-80.
11. VPAC1 (vasoactive intestinal peptide (VIP) receptor type 1) G protein-coupled receptor mediation of VIP enhancement of murine experimental colitis. Yadav M, etal., Cell Immunol. 2011;267(2):124-32. Epub 2011 Jan 7.
Additional References at PubMed
PMID:15176082   PMID:15344914   PMID:15514088   PMID:15670850   PMID:16202621   PMID:16888168   PMID:16888209   PMID:18665096   PMID:20599818   PMID:22766684   PMID:23099490   PMID:23518767  
PMID:28776455   PMID:36430275   PMID:36642263  


Genomics

Comparative Map Data
Vipr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86143,139,672 - 143,213,609 (+)NCBIGRCr8
mRatBN7.26136,996,664 - 137,070,599 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6137,001,511 - 137,070,597 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6140,436,878 - 140,505,908 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06137,061,345 - 137,130,423 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06137,609,234 - 137,678,261 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06143,932,960 - 144,009,476 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6143,938,040 - 144,008,072 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06152,871,204 - 152,945,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,347,748 - 143,416,680 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16143,353,934 - 143,422,867 (+)NCBI
Celera6134,667,982 - 134,736,986 (+)NCBICelera
Cytogenetic Map6q33NCBI
VIPR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387159,028,175 - 159,144,867 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7159,028,175 - 159,144,867 (-)EnsemblGRCh38hg38GRCh38
GRCh377158,820,866 - 158,937,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367158,513,627 - 158,630,410 (-)NCBINCBI36Build 36hg18NCBI36
Build 347158,320,342 - 158,437,125NCBI
Celera7153,254,268 - 153,370,389 (-)NCBICelera
Cytogenetic Map7q36.3NCBI
HuRef7152,560,564 - 152,677,411 (-)NCBIHuRef
CHM1_17158,828,828 - 158,945,965 (-)NCBICHM1_1
T2T-CHM13v2.07160,254,532 - 160,371,379 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27158,024,240 - 158,139,944 (-)NCBI
Vipr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912116,041,040 - 116,117,842 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12116,041,346 - 116,109,881 (+)EnsemblGRCm39 Ensembl
GRCm3812116,077,420 - 116,148,637 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12116,077,726 - 116,146,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712117,316,196 - 117,384,734 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612116,519,807 - 116,587,384 (+)NCBIMGSCv36mm8
MGSCv3612110,280,083 - 110,347,578 (+)NCBIMGSCv36mm8
Cytogenetic Map12F2NCBI
cM Map1262.59NCBI
Vipr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555791,160,620 - 1,209,848 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555791,160,620 - 1,212,711 (-)NCBIChiLan1.0ChiLan1.0
VIPR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26195,535,133 - 195,653,430 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1747,545,399 - 47,663,696 (-)NCBINHGRI_mPanPan1
PanPan1.17162,306,477 - 162,425,860 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7162,306,477 - 162,422,788 (-)Ensemblpanpan1.1panPan2
VIPR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11620,925,032 - 20,987,513 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1620,927,991 - 20,987,785 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1621,432,331 - 21,491,528 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01622,660,335 - 22,719,946 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1622,660,344 - 22,719,998 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11621,028,013 - 21,087,077 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01621,611,058 - 21,670,421 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01621,665,914 - 21,725,151 (-)NCBIUU_Cfam_GSD_1.0
Vipr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118328,956 - 410,359 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936856859,009 - 866,239 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VIPR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18396,263 - 518,102 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118396,379 - 466,408 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218663,352 - 732,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VIPR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121126,917,862 - 127,022,834 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21126,917,880 - 127,022,758 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607223,466,663 - 23,573,079 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vipr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624800125,686 - 180,590 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624800125,732 - 188,200 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Vipr2
389 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:240
Count of miRNA genes:166
Interacting mature miRNAs:204
Transcripts:ENSRNOT00000005876
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat

Markers in Region
AA818985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,026,116 - 137,026,330 (+)MAPPERmRatBN7.2
Rnor_6.06143,962,568 - 143,962,781NCBIRnor6.0
Rnor_5.06152,900,814 - 152,901,027UniSTSRnor5.0
RGSC_v3.46143,372,355 - 143,372,568UniSTSRGSC3.4
Celera6134,692,589 - 134,692,802UniSTS
RH 3.4 Map6916.0UniSTS
Cytogenetic Map6q33UniSTS
RH132714  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,070,351 - 137,070,551 (+)MAPPERmRatBN7.2
Rnor_6.06144,006,783 - 144,006,982NCBIRnor6.0
Rnor_5.06152,945,029 - 152,945,228UniSTSRnor5.0
RGSC_v3.46143,416,435 - 143,416,634UniSTSRGSC3.4
Celera6134,736,741 - 134,736,940UniSTS
RH 3.4 Map6914.1UniSTS
Cytogenetic Map6q33UniSTS
RH139640  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,007,693 - 137,007,898 (+)MAPPERmRatBN7.2
Rnor_6.06143,944,144 - 143,944,348NCBIRnor6.0
Rnor_5.06152,882,390 - 152,882,594UniSTSRnor5.0
RGSC_v3.46143,353,931 - 143,354,135UniSTSRGSC3.4
Celera6134,674,165 - 134,674,369UniSTS
RH 3.4 Map6916.3UniSTS
Cytogenetic Map6q33UniSTS
UniSTS:224723  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,068,736 - 137,068,891 (+)MAPPERmRatBN7.2
Rnor_6.06144,005,168 - 144,005,322NCBIRnor6.0
Rnor_5.06152,943,414 - 152,943,568UniSTSRnor5.0
RGSC_v3.46143,414,820 - 143,414,974UniSTSRGSC3.4
Celera6134,735,126 - 134,735,280UniSTS
Cytogenetic Map6q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000005876   ⟹   ENSRNOP00000005876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6137,001,511 - 137,070,597 (+)Ensembl
Rnor_6.0 Ensembl6143,938,040 - 144,008,072 (+)Ensembl
RefSeq Acc Id: NM_017238   ⟹   NP_058934
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86143,144,523 - 143,213,609 (+)NCBI
mRatBN7.26137,001,511 - 137,070,597 (+)NCBI
Rnor_6.06143,937,961 - 144,007,028 (+)NCBI
Rnor_5.06152,871,204 - 152,945,276 (+)NCBI
RGSC_v3.46143,347,748 - 143,416,680 (+)RGD
Celera6134,667,982 - 134,736,986 (+)RGD
Sequence:
RefSeq Acc Id: XM_017594055   ⟹   XP_017449544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86143,139,672 - 143,213,609 (+)NCBI
mRatBN7.26136,996,664 - 137,070,599 (+)NCBI
Rnor_6.06143,932,960 - 144,007,028 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039111850   ⟹   XP_038967778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86143,144,494 - 143,213,609 (+)NCBI
mRatBN7.26137,001,486 - 137,070,599 (+)NCBI
RefSeq Acc Id: XM_039111851   ⟹   XP_038967779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86143,160,493 - 143,213,609 (+)NCBI
mRatBN7.26137,017,480 - 137,070,599 (+)NCBI
RefSeq Acc Id: XM_039111852   ⟹   XP_038967780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86143,144,496 - 143,210,182 (+)NCBI
mRatBN7.26137,001,487 - 137,067,252 (+)NCBI
RefSeq Acc Id: XM_039111853   ⟹   XP_038967781
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86143,144,479 - 143,163,537 (+)NCBI
mRatBN7.26137,001,275 - 137,020,533 (+)NCBI
RefSeq Acc Id: XM_063261586   ⟹   XP_063117656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86143,143,846 - 143,213,609 (+)NCBI
RefSeq Acc Id: XR_005505447
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86143,144,497 - 143,210,166 (+)NCBI
mRatBN7.26137,001,488 - 137,067,252 (+)NCBI
RefSeq Acc Id: NP_058934   ⟸   NM_017238
- Peptide Label: precursor
- UniProtKB: P35000 (UniProtKB/Swiss-Prot),   A6KDK7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449544   ⟸   XM_017594055
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000005876   ⟸   ENSRNOT00000005876
RefSeq Acc Id: XP_038967781   ⟸   XM_039111853
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038967778   ⟸   XM_039111850
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038967780   ⟸   XM_039111852
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038967779   ⟸   XM_039111851
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063117656   ⟸   XM_063261586
- Peptide Label: isoform X1
Protein Domains
G-protein coupled receptors family 2 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35000-F1-model_v2 AlphaFold P35000 1-437 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694906
Promoter ID:EPDNEW_R5430
Type:single initiation site
Name:Vipr2_1
Description:vasoactive intestinal peptide receptor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06143,938,031 - 143,938,091EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3962 AgrOrtholog
BioCyc Gene G2FUF-35516 BioCyc
Ensembl Genes ENSRNOG00000004317 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055005107 UniProtKB/Swiss-Prot
  ENSRNOG00060014602 UniProtKB/Swiss-Prot
  ENSRNOG00065007208 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005876.5 UniProtKB/Swiss-Prot
  ENSRNOT00055008189 UniProtKB/Swiss-Prot
  ENSRNOT00060024946 UniProtKB/Swiss-Prot
  ENSRNOT00065011216 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.1240.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 7tmB1_VIP-R2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_VIP_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_VIP_rcpt_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29555 UniProtKB/Swiss-Prot
NCBI Gene 29555 ENTREZGENE
PANTHER PDF RECEPTOR-LIKE PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45620:SF22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Vipr2 PhenoGen
PRINTS GPCRSECRETIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VASOACTVEIPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VIP2RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004317 RatGTEx
  ENSRNOG00055005107 RatGTEx
  ENSRNOG00060014602 RatGTEx
  ENSRNOG00065007208 RatGTEx
SMART HormR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hormone receptor domain UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
TIGR TC232082
UniProt A6KDK7 ENTREZGENE, UniProtKB/TrEMBL
  A6KDK8_RAT UniProtKB/TrEMBL
  P35000 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Vipr2  vasoactive intestinal peptide receptor 2    vasopressive intestinal peptide receptor 2  Name updated 1299863 APPROVED
2002-06-10 Vipr2  vasopressive intestinal peptide receptor 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expressed in areas associated with neuroendocrine function, including hypothalamic nuclei, pituitary and pancreatic islets 70053
gene_physical_interaction may also bind growth hormone releasing hormone and peptide histidine isoleucine 70054
gene_process stimulates cAMP production in response to VIP binding 70053
gene_product member of the secretin/calcitonin/parathyroid hormone receptor family 70054