Syt5 (synaptotagmin 5) - Rat Genome Database

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Gene: Syt5 (synaptotagmin 5) Rattus norvegicus
Analyze
Symbol: Syt5
Name: synaptotagmin 5
RGD ID: 3806
Description: Enables calcium-dependent phospholipid binding activity; clathrin binding activity; and syntaxin binding activity. Predicted to be involved in calcium-dependent activation of synaptic vesicle fusion; regulation of calcium ion-dependent exocytosis; and regulation of synaptic vesicle exocytosis. Predicted to be located in neuronal cell body; perinuclear region of cytoplasm; and proximal neuron projection. Predicted to be active in axon; plasma membrane; and secretory vesicle. Orthologous to human SYT5 (synaptotagmin 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC105442; synaptotagmin IX; synaptotagmin V; synaptotagmin-5; SytIX; sytV
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,320,034 - 78,327,750 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,320,034 - 78,327,746 (+)EnsemblGRCr8
mRatBN7.2169,277,351 - 69,285,071 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,277,351 - 69,285,067 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx174,636,273 - 74,643,984 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,200,582 - 83,208,291 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,350,203 - 76,357,904 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,859,806 - 72,867,934 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,860,218 - 72,867,930 (+)Ensemblrn6Rnor6.0
Rnor_5.0175,683,287 - 75,691,003 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4168,005,337 - 68,013,052 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera167,844,074 - 67,850,141 (-)NCBICelera
RGSC_v3.1168,083,447 - 68,091,163 (+)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Synaptotagmin V: a novel synaptotagmin isoform expressed in rat brain. Craxton M and Goedert M, FEBS Lett 1995 Mar 20;361(2-3):196-200.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Identification of a nonneuronal isoform of synaptotagmin. Hudson AW and Birnbaum MJ, Proc Natl Acad Sci U S A 1995 Jun 20;92(13):5895-9.
5. Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Li C, etal., Nature 1995 Jun 15;375(6532):594-9.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Synaptotagmin V is targeted to dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells. Saegusa C, etal., J Biol Chem 2002 Jul 5;277(27):24499-505.
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:8626542   PMID:10531344   PMID:12477932   PMID:12860971   PMID:12966166   PMID:14622145   PMID:15190121   PMID:15197251   PMID:15784685   PMID:16407767   PMID:17264148   PMID:22871113  
PMID:27793683  


Genomics

Comparative Map Data
Syt5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,320,034 - 78,327,750 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,320,034 - 78,327,746 (+)EnsemblGRCr8
mRatBN7.2169,277,351 - 69,285,071 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,277,351 - 69,285,067 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx174,636,273 - 74,643,984 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,200,582 - 83,208,291 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,350,203 - 76,357,904 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,859,806 - 72,867,934 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,860,218 - 72,867,930 (+)Ensemblrn6Rnor6.0
Rnor_5.0175,683,287 - 75,691,003 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4168,005,337 - 68,013,052 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera167,844,074 - 67,850,141 (-)NCBICelera
RGSC_v3.1168,083,447 - 68,091,163 (+)NCBI
Cytogenetic Map1q12NCBI
SYT5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,171,196 - 55,180,289 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,171,196 - 55,180,314 (-)Ensemblhg38GRCh38
GRCh371955,682,564 - 55,691,657 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,376,281 - 60,383,532 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341960,376,280 - 60,382,727NCBI
Celera1952,725,663 - 52,732,913 (-)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,007,463 - 52,014,713 (-)NCBIHuRef
CHM1_11955,678,042 - 55,685,293 (-)NCBICHM1_1
T2T-CHM13v2.01958,265,259 - 58,274,351 (-)NCBIT2T-CHM13v2.0
Syt5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,542,764 - 4,550,540 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,542,764 - 4,550,540 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3874,539,765 - 4,547,541 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,539,765 - 4,547,541 (-)Ensemblmm10GRCm38
MGSCv3774,491,367 - 4,498,169 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3674,142,852 - 4,149,654 (-)NCBIMGSCv36mm8
Celera74,285,056 - 4,291,862 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.62NCBI
Syt5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555671,018,433 - 1,024,477 (+)Ensembl
ChiLan1.0NW_0049555671,018,433 - 1,024,477 (+)NCBIChiLan1.0ChiLan1.0
SYT5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,309,394 - 61,316,614 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,038,519 - 63,045,936 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,214,261 - 52,221,678 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11960,909,026 - 60,916,436 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1960,909,026 - 60,916,436 (-)EnsemblpanPan2panpan1.1
SYT5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,456,767 - 102,463,750 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,456,782 - 102,463,749 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1102,513,991 - 102,520,804 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01103,110,511 - 103,117,325 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1103,109,988 - 103,117,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,747,442 - 102,754,253 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,459,003 - 102,465,825 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,223,057 - 103,229,871 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Syt5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093492,102,191 - 2,108,616 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886449,194 - 457,088 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936886451,400 - 457,093 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYT5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,381,642 - 59,389,298 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1659,381,649 - 59,389,014 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2654,276,396 - 54,283,759 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SYT5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1647,768,567 - 47,776,010 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl647,768,545 - 47,774,732 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236668079,678 - 17,212 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syt5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248322,071,770 - 2,078,376 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248322,071,782 - 2,080,680 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Syt5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12177,139,790 - 177,147,653 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Syt5
65 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:209
Count of miRNA genes:126
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000024547
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
AA998567  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2169,284,867 - 69,285,065 (+)MAPPERmRatBN7.2
Rnor_6.0172,867,731 - 72,867,928NCBIRnor6.0
Rnor_5.0175,683,293 - 75,683,490UniSTSRnor5.0
RGSC_v3.4168,012,853 - 68,013,050UniSTSRGSC3.4
Cytogenetic Map1q12UniSTS
BE111620  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2169,278,075 - 69,278,231 (+)MAPPERmRatBN7.2
Rnor_6.0172,860,943 - 72,861,098NCBIRnor6.0
Rnor_5.0175,690,123 - 75,690,278UniSTSRnor5.0
RGSC_v3.4168,006,062 - 68,006,217UniSTSRGSC3.4
Celera167,849,261 - 67,849,416UniSTS
Cytogenetic Map1q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 158 90 89 59 86 59 6 345 186 11 137 76 92 30 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000024547   ⟹   ENSRNOP00000024547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl178,320,034 - 78,327,746 (+)Ensembl
mRatBN7.2 Ensembl169,277,351 - 69,285,067 (+)Ensembl
Rnor_6.0 Ensembl172,860,218 - 72,867,930 (+)Ensembl
RefSeq Acc Id: NM_019350   ⟹   NP_062223
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,320,034 - 78,327,746 (+)NCBI
mRatBN7.2169,277,351 - 69,285,067 (+)NCBI
Rnor_6.0172,860,218 - 72,867,930 (+)NCBI
Rnor_5.0175,683,287 - 75,691,003 (-)NCBI
RGSC_v3.4168,005,337 - 68,013,052 (+)RGD
Celera167,844,074 - 67,850,141 (-)RGD
Sequence:
RefSeq Acc Id: XM_006228287   ⟹   XP_006228349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,321,206 - 78,327,750 (+)NCBI
mRatBN7.2169,277,475 - 69,285,071 (+)NCBI
Rnor_6.0172,859,806 - 72,867,934 (+)NCBI
Rnor_5.0175,683,287 - 75,691,003 (-)NCBI
Sequence:
RefSeq Acc Id: NP_062223   ⟸   NM_019350
- UniProtKB: Q56A28 (UniProtKB/Swiss-Prot),   P47861 (UniProtKB/Swiss-Prot),   A6KNM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228349   ⟸   XM_006228287
- Peptide Label: isoform X1
- UniProtKB: A6KNM3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024547   ⟸   ENSRNOT00000024547
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47861-F1-model_v2 AlphaFold P47861 1-386 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3806 AgrOrtholog
BioCyc Gene G2FUF-60841 BioCyc
Ensembl Genes ENSRNOG00000018217 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024547 ENTREZGENE
  ENSRNOT00000024547.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot
InterPro C2_dom UniProtKB/Swiss-Prot
  C2_domain_sf UniProtKB/Swiss-Prot
  Synaptotagmin UniProtKB/Swiss-Prot
KEGG Report rno:54309 UniProtKB/Swiss-Prot
NCBI Gene 54309 ENTREZGENE
PANTHER PTHR10024:SF282 UniProtKB/Swiss-Prot
  SYNAPTOTAGMIN UniProtKB/Swiss-Prot
Pfam PF00168 UniProtKB/Swiss-Prot
PhenoGen Syt5 PhenoGen
PRINTS C2DOMAIN UniProtKB/Swiss-Prot
  SYNAPTOTAGMN UniProtKB/Swiss-Prot
PROSITE PS50004 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018217 RatGTEx
SMART SM00239 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot
TIGR TC232072
UniProt A6KNM3 ENTREZGENE, UniProtKB/TrEMBL
  P47861 ENTREZGENE
  Q56A28 ENTREZGENE
  SYT5_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q56A28 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Syt5  synaptotagmin 5  Syt5  synaptotagmin V  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Syt5  synaptotagmin V    synaptotagmin 5  Name updated 1299863 APPROVED
2002-06-10 Syt5  synaptotagmin 5      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to dense core vesicles 730140
gene_expression expressed in kidney, adipose tissue, lung and heart; highly expressed in brain and PC12 cells 70031
gene_expression expressed at high levels in brain but not in spinal cord or non-neuronal peripheral tissues 70032
gene_homology 49% identity to synaptotagmin-1 and synaptotagmin-2 70031
gene_homology 54% identical to synaptotagmin I 70032
gene_protein 386 amino acid protein 70032