Eef1a2 (eukaryotic translation elongation factor 1 alpha 2) - Rat Genome Database

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Gene: Eef1a2 (eukaryotic translation elongation factor 1 alpha 2) Rattus norvegicus
Analyze
Symbol: Eef1a2
Name: eukaryotic translation elongation factor 1 alpha 2
RGD ID: 3781
Description: Predicted to enable GTPase activity; protein kinase binding activity; and translation elongation factor activity. Involved in regulation of postsynaptic specialization assembly and response to electrical stimulus. Located in neuronal cell body. Is active in GABA-ergic synapse. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 38; developmental and epileptic encephalopathy 33; and ovarian cancer. Orthologous to human EEF1A2 (eukaryotic translation elongation factor 1 alpha 2); PARTICIPATES IN RNA transport pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: eEF1A-2; EEF1AL; EF-1-alpha-2; elongation factor 1 A-2; elongation factor 1-alpha 2; eukaryotic elongation factor 1 A-2; Ps10; RATPS10; statin S1; statin-like; statin-S1; STN; Stnl
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bp285
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,643,455 - 188,652,633 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3188,643,458 - 188,677,712 (-)EnsemblGRCr8
mRatBN7.23168,265,893 - 168,275,071 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,195,357 - 168,275,071 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3172,646,092 - 172,655,298 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,605,190 - 181,614,396 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,266,847 - 178,276,025 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,657,104 - 176,666,282 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,657,107 - 176,666,282 (-)Ensemblrn6Rnor6.0
Rnor_5.03180,367,136 - 180,376,314 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43170,295,327 - 170,304,505 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3164,310,775 - 164,319,957 (+)NCBICelera
RGSC_v3.13170,201,363 - 170,210,541 (-)NCBI
Cytogenetic Map3q43NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(Z)-3-butylidenephthalide  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
butyric acid  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chlormequat chloride  (EXP)
cisplatin  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Echimidine  (EXP)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
fructose  (EXP)
genistein  (ISO)
glyphosate  (ISO)
graphite  (EXP,ISO)
Heliotrine  (EXP)
ivermectin  (ISO)
LY294002  (ISO)
methapyrilene  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosomorpholine  (EXP)
nitrofen  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
paracetamol  (EXP)
paraquat  (ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
PF-3758309  (ISO)
phenethyl isothiocyanate  (EXP)
pioglitazone  (ISO)
Platyphylline  (EXP)
potassium dichromate  (ISO)
propanal  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrahydropalmatine  (ISO)
thapsigargin  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
triclosan  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
wortmannin  (ISO)
XL147  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer. Anand N, etal., Nat Genet. 2002 Jul;31(3):301-5. Epub 2002 Jun 10.
2. Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin. Ann DK, etal., J Biol Chem 1991 Jun 5;266(16):10429-37.
3. Effects of two elongation factor 1A isoforms on the formation of gephyrin clusters at inhibitory synapses in hippocampal neurons. Becker M, etal., Histochem Cell Biol. 2013 Dec;140(6):603-9. doi: 10.1007/s00418-013-1122-9. Epub 2013 Jul 10.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Novel interaction between the M4 muscarinic acetylcholine receptor and elongation factor 1A2. McClatchy DB, etal., J Biol Chem 2002 Aug 9;277(32):29268-74.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Upregulation by KCl treatment of eukaryotic translation elongation factor 1A (eEF1A) mRNA in the dendrites of cultured rat hippocampal neurons. Moon IS, etal., Mol Cells. 2008 Jun 30;25(4):538-44. Epub 2008 Apr 24.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. Increased levels of statin, a marker of cell cycle arrest, in response to hippocampal neuronal injury. Poirier J, etal., Brain Res Mol Brain Res. 1995 Dec 1;34(1):57-64.
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:9588196   PMID:11724805   PMID:12426392   PMID:15013623   PMID:15489334   PMID:16452087   PMID:17088255   PMID:17634366   PMID:18474610   PMID:21700703   PMID:22871113   PMID:24625528  
PMID:26316108   PMID:32357304   PMID:35352799  


Genomics

Comparative Map Data
Eef1a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,643,455 - 188,652,633 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3188,643,458 - 188,677,712 (-)EnsemblGRCr8
mRatBN7.23168,265,893 - 168,275,071 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,195,357 - 168,275,071 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3172,646,092 - 172,655,298 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,605,190 - 181,614,396 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,266,847 - 178,276,025 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,657,104 - 176,666,282 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,657,107 - 176,666,282 (-)Ensemblrn6Rnor6.0
Rnor_5.03180,367,136 - 180,376,314 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43170,295,327 - 170,304,505 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3164,310,775 - 164,319,957 (+)NCBICelera
RGSC_v3.13170,201,363 - 170,210,541 (-)NCBI
Cytogenetic Map3q43NCBI
EEF1A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382063,488,014 - 63,499,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2063,477,488 - 63,500,533 (-)Ensemblhg38GRCh38
GRCh372062,119,367 - 62,130,436 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362061,589,810 - 61,600,949 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342061,589,809 - 61,600,949NCBI
Celera2058,799,722 - 58,810,854 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2058,848,703 - 58,860,885 (-)NCBIHuRef
CHM1_12062,020,420 - 62,031,789 (-)NCBICHM1_1
T2T-CHM13v2.02065,299,508 - 65,311,765 (-)NCBIT2T-CHM13v2.0
Eef1a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392180,783,551 - 180,798,808 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2180,778,581 - 180,798,807 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382181,141,758 - 181,157,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2181,147,653 - 181,157,014 (-)Ensemblmm10GRCm38
MGSCv372180,882,397 - 180,891,720 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362181,077,100 - 181,086,422 (-)NCBIMGSCv36mm8
Celera2185,234,189 - 185,243,512 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.6NCBI
Eef1a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955528717,338 - 729,692 (+)Ensembl
ChiLan1.0NW_004955528717,338 - 726,383 (+)NCBIChiLan1.0ChiLan1.0
EEF1A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,290,289 - 69,302,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12069,282,295 - 69,294,390 (-)NCBINHGRI_mPanPan1
PanPan1.12061,412,059 - 61,421,820 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2061,412,122 - 61,421,735 (-)EnsemblpanPan2panpan1.1
LOC487375
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,787,450 - 75,797,662 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha272,357,766 - 72,367,782 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0276,347,000 - 76,357,024 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1273,169,322 - 73,179,344 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,176,170 - 74,186,373 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,181,724 - 75,191,917 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Eef1a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,345,359 - 195,353,489 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,798,671 - 10,807,132 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,799,002 - 10,807,132 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EEF1A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,517,503 - 62,526,190 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11762,517,811 - 62,526,379 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EEF1A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12712,020 - 724,843 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2713,522 - 724,859 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605048,273,352 - 48,285,738 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eef1a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474129,154,993 - 29,163,799 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474129,154,762 - 29,163,794 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Eef1a2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15158,252,991 - 158,262,270 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:61
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000016947
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3181611379189428310Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat

Markers in Region
D3Wox8  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,266,540 - 168,266,819 (+)MAPPERmRatBN7.2
Rnor_6.03176,657,752 - 176,658,030NCBIRnor6.0
Rnor_5.03180,367,784 - 180,368,062UniSTSRnor5.0
RGSC_v3.43170,295,974 - 170,296,253RGDRGSC3.4
RGSC_v3.43170,295,975 - 170,296,253UniSTSRGSC3.4
Celera3164,319,027 - 164,319,309UniSTS
RGSC_v3.13170,202,010 - 170,202,289RGD
Cytogenetic Map3q43UniSTS
D3Arb15  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83188,644,107 - 188,644,453 (+)Marker Load Pipeline
mRatBN7.23168,266,545 - 168,266,891 (+)MAPPERmRatBN7.2
Rnor_6.03176,657,757 - 176,658,102NCBIRnor6.0
Rnor_5.03180,367,789 - 180,368,134UniSTSRnor5.0
RGSC_v3.43170,295,979 - 170,296,325RGDRGSC3.4
RGSC_v3.43170,295,980 - 170,296,325UniSTSRGSC3.4
Celera3164,318,955 - 164,319,304UniSTS
RGSC_v3.13170,202,016 - 170,202,361RGD
RH 3.4 Map31539.0RGD
RH 3.4 Map31539.0UniSTS
RH 2.0 Map31055.9RGD
SHRSP x BN Map391.4899RGD
Cytogenetic Map3q43UniSTS
D3Mgh27  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83188,644,107 - 188,644,253 (+)Marker Load Pipeline
mRatBN7.23168,266,545 - 168,266,691 (+)MAPPERmRatBN7.2
Rnor_6.03176,657,757 - 176,657,902NCBIRnor6.0
Rnor_5.03180,367,789 - 180,367,934UniSTSRnor5.0
RGSC_v3.43170,295,980 - 170,296,125UniSTSRGSC3.4
RGSC_v3.43170,295,979 - 170,296,125RGDRGSC3.4
Celera3164,319,155 - 164,319,304UniSTS
RGSC_v3.13170,202,015 - 170,202,161RGD
RH 3.4 Map31541.3RGD
RH 3.4 Map31541.3UniSTS
RH 2.0 Map31057.5RGD
SHRSP x BN Map391.5299RGD
Cytogenetic Map3q43UniSTS
D3Mco31  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,266,538 - 168,266,827 (+)MAPPERmRatBN7.2
Rnor_6.03176,657,750 - 176,658,038NCBIRnor6.0
Rnor_5.03180,367,782 - 180,368,070UniSTSRnor5.0
RGSC_v3.43170,295,973 - 170,296,261UniSTSRGSC3.4
RGSC_v3.43170,295,972 - 170,296,261RGDRGSC3.4
Celera3164,319,019 - 164,319,311UniSTS
Cytogenetic Map3q43UniSTS
Eef1a2  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.43170,295,728 - 170,296,358UniSTSRGSC3.4
RGSC_v3.43170,295,332 - 170,295,464UniSTSRGSC3.4
Celera3164,318,922 - 164,319,556UniSTS
Celera3164,319,820 - 164,319,952UniSTS
L26479  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,265,894 - 168,266,055 (+)MAPPERmRatBN7.2
Rnor_6.03176,657,106 - 176,657,266NCBIRnor6.0
Rnor_5.03180,367,138 - 180,367,298UniSTSRnor5.0
RGSC_v3.43170,295,329 - 170,295,489UniSTSRGSC3.4
Celera3164,319,795 - 164,319,955UniSTS
Cytogenetic Map3q43UniSTS
Eef1a2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.03180,367,141 - 180,367,273UniSTSRnor5.0
RGSC_v3.43170,295,332 - 170,295,464UniSTSRGSC3.4
Celera3164,319,820 - 164,319,952UniSTS
Cytogenetic Map3q43UniSTS
Eef1a2  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83188,643,855 - 188,644,486 (+)Marker Load Pipeline
Rnor_5.03180,367,537 - 180,368,167UniSTSRnor5.0
RGSC_v3.43170,295,728 - 170,296,358UniSTSRGSC3.4
Celera3164,318,922 - 164,319,556UniSTS
Cytogenetic Map3q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 12 66 159 88 87 56 41 56 6 294 140 11 131 76 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000016947   ⟹   ENSRNOP00000016947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3188,643,458 - 188,652,633 (-)Ensembl
mRatBN7.2 Ensembl3168,199,994 - 168,275,071 (-)Ensembl
Rnor_6.0 Ensembl3176,657,107 - 176,666,282 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000049961   ⟹   ENSRNOP00000040830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,198,787 - 168,253,740 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094525   ⟹   ENSRNOP00000094215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,195,357 - 168,253,740 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102525   ⟹   ENSRNOP00000083195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,198,787 - 168,253,740 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105837   ⟹   ENSRNOP00000094928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,198,787 - 168,253,740 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109229   ⟹   ENSRNOP00000094730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,195,371 - 168,253,740 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112753   ⟹   ENSRNOP00000090613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3188,643,458 - 188,677,712 (-)Ensembl
RefSeq Acc Id: NM_012660   ⟹   NP_036792
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,643,455 - 188,652,633 (-)NCBI
mRatBN7.23168,265,893 - 168,275,071 (-)NCBI
Rnor_6.03176,657,104 - 176,666,282 (-)NCBI
Rnor_5.03180,367,136 - 180,376,314 (-)NCBI
RGSC_v3.43170,295,327 - 170,304,505 (-)RGD
Celera3164,310,775 - 164,319,957 (+)RGD
Sequence:
RefSeq Acc Id: XM_063283109   ⟹   XP_063139179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,643,455 - 188,651,675 (-)NCBI
RefSeq Acc Id: NP_036792   ⟸   NM_012660
- UniProtKB: P62632 (UniProtKB/Swiss-Prot),   P27706 (UniProtKB/Swiss-Prot),   A6KM48 (UniProtKB/TrEMBL),   A0A8L2Q996 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016947   ⟸   ENSRNOT00000016947
Ensembl Acc Id: ENSRNOP00000094215   ⟸   ENSRNOT00000094525
Ensembl Acc Id: ENSRNOP00000094730   ⟸   ENSRNOT00000109229
Ensembl Acc Id: ENSRNOP00000040830   ⟸   ENSRNOT00000049961
Ensembl Acc Id: ENSRNOP00000094928   ⟸   ENSRNOT00000105837
Ensembl Acc Id: ENSRNOP00000083195   ⟸   ENSRNOT00000102525
RefSeq Acc Id: XP_063139179   ⟸   XM_063283109
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q996 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000090613   ⟸   ENSRNOT00000112753
Protein Domains
GTP-eEF1A C-terminal   Ion transport   Potassium channel voltage dependent KCNQ C-terminal   tr-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62632-F1-model_v2 AlphaFold P62632 1-463 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692746
Promoter ID:EPDNEW_R3271
Type:multiple initiation site
Name:Eef1a2_1
Description:eukaryotic translation elongation factor 1 alpha 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03176,666,056 - 176,666,116EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3781 AgrOrtholog
BioCyc Gene G2FUF-46304 BioCyc
Ensembl Genes ENSRNOG00000011624 Ensembl
  ENSRNOG00000012477 Ensembl
  ENSRNOG00000072254 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000016947 ENTREZGENE
  ENSRNOT00000112753 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
  Translation factors UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7105980 IMAGE-MGC_LOAD
InterPro EFTu-like_2 UniProtKB/Swiss-Prot
  G_TR_CS UniProtKB/Swiss-Prot
  GTP-eEF1A_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  TF_GTP-bd_dom UniProtKB/Swiss-Prot
  TRAFAC_GTPase_members UniProtKB/Swiss-Prot
  Transl_B-barrel_sf UniProtKB/Swiss-Prot
  Transl_elong_EF1A/Init_IF2_C UniProtKB/Swiss-Prot
  Transl_elong_EF1A_euk/arc UniProtKB/Swiss-Prot
KEGG Report rno:24799 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91772 IMAGE-MGC_LOAD
NCBI Gene 24799 ENTREZGENE
PANTHER TRANSLATION FACTOR UniProtKB/Swiss-Prot
Pfam GTP-eEF1A_C UniProtKB/Swiss-Prot
  GTP_EFTU UniProtKB/Swiss-Prot
  GTP_EFTU_D2 UniProtKB/Swiss-Prot
PhenoGen Eef1a2 PhenoGen
PRINTS ELONGATNFCT UniProtKB/Swiss-Prot
PROSITE G_TR_1 UniProtKB/Swiss-Prot
  G_TR_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011624 RatGTEx
  ENSRNOG00000012477 RatGTEx
  ENSRNOG00000072254 RatGTEx
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot
  SSF50465 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
TIGR TC204611
UniProt A0A8I6AEM9_RAT UniProtKB/TrEMBL
  A0A8I6GKM5_RAT UniProtKB/TrEMBL
  A0A8L2Q996 ENTREZGENE, UniProtKB/TrEMBL
  A6KM47_RAT UniProtKB/TrEMBL
  A6KM48 ENTREZGENE, UniProtKB/TrEMBL
  A6KM49_RAT UniProtKB/TrEMBL
  EF1A2_RAT UniProtKB/Swiss-Prot
  P27706 ENTREZGENE
  P62632 ENTREZGENE
UniProt Secondary P27706 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-01-12 Eef1a2  eukaryotic translation elongation factor 1 alpha 2  Stnl  statin-like  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2003-04-09 Stnl  statin-like    Statin-like protein  Name updated 629478 APPROVED
2002-06-10 Stnl  Statin-like protein      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_homology highly homologous to human EF-1 alpha gene 634174
gene_transcript 47 kb in size 634174