Sp4 (Sp4 transcription factor) - Rat Genome Database

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Gene: Sp4 (Sp4 transcription factor) Rattus norvegicus
Analyze
Symbol: Sp4
Name: Sp4 transcription factor
RGD ID: 3741
Description: Enables DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of heart contraction. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Orthologous to human SP4 (Sp4 transcription factor); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HF-1b; HF-1b zinc finger protein; Trans-acting transcription factor 4; transcription factor Sp4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86145,330,416 - 145,395,750 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6145,330,416 - 145,395,146 (-)EnsemblGRCr8
mRatBN7.26139,187,458 - 139,252,741 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6139,192,147 - 139,252,126 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6142,629,275 - 142,693,969 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06139,246,735 - 139,311,441 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06139,795,393 - 139,860,091 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06146,135,877 - 146,201,344 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6146,135,877 - 146,195,819 (-)Ensemblrn6Rnor6.0
Rnor_5.06155,047,728 - 155,113,698 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46145,553,512 - 145,619,389 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6136,844,006 - 136,908,926 (-)NCBICelera
RGSC_v3.16145,559,698 - 145,620,144 (-)NCBI
Cytogenetic Map6q33NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
coumarin  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
FR900359  (ISO)
furan  (EXP)
geldanamycin  (ISO)
glutathione  (ISO)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
L-ascorbic acid  (ISO)
metformin  (ISO)
methimazole  (EXP)
methylmercury chloride  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quercitrin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (ISO)
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Transcriptional regulation of P450scc gene expression in the embryonic rodent nervous system. Hammer F, etal., Endocrinology 2004 Feb;145(2):901-12. Epub 2003 Oct 23.
4. Knockout of the neural and heart expressed gene HF-1b results in apical deficits of ventricular structure and activation. Hewett KW, etal., Cardiovasc Res. 2005 Aug 15;67(3):548-60.
5. Functional analysis of the rat N-methyl-D-aspartate receptor 2A promoter: multiple transcription starts points, positive regulation by Sp factors, and translational regulation. Liu A, etal., J Biol Chem. 2003 Jul 18;278(29):26423-34. Epub 2003 May 13.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Expression of an LMNA-N195K variant of A-type lamins results in cardiac conduction defects and death in mice. Mounkes LC, etal., Hum Mol Genet. 2005 Aug 1;14(15):2167-80. Epub 2005 Jun 22.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages. Nguyen-Tran VT, etal., Cell. 2000 Sep 1;102(5):671-82.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Sp3 proteins negatively regulate beta myosin heavy chain gene expression during skeletal muscle inactivity. Tsika G, etal., Mol Cell Biol. 2004 Dec;24(24):10777-91.
14. A novel, tissue-restricted zinc finger protein (HF-1b) binds to the cardiac regulatory element (HF-1b/MEF-2) in the rat myosin light-chain 2 gene. Zhu H, etal., Mol Cell Biol 1993 Jul;13(7):4432-44.
Additional References at PubMed
PMID:12560508   PMID:17535924   PMID:19555762   PMID:21645329   PMID:23332764   PMID:24475768   PMID:24894994   PMID:26037489   PMID:26469128  


Genomics

Comparative Map Data
Sp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86145,330,416 - 145,395,750 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6145,330,416 - 145,395,146 (-)EnsemblGRCr8
mRatBN7.26139,187,458 - 139,252,741 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6139,192,147 - 139,252,126 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6142,629,275 - 142,693,969 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06139,246,735 - 139,311,441 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06139,795,393 - 139,860,091 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06146,135,877 - 146,201,344 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6146,135,877 - 146,195,819 (-)Ensemblrn6Rnor6.0
Rnor_5.06155,047,728 - 155,113,698 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46145,553,512 - 145,619,389 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6136,844,006 - 136,908,926 (-)NCBICelera
RGSC_v3.16145,559,698 - 145,620,144 (-)NCBI
Cytogenetic Map6q33NCBI
SP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38721,428,083 - 21,514,822 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl721,428,043 - 21,514,822 (+)Ensemblhg38GRCh38
GRCh37721,467,701 - 21,554,440 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36721,434,214 - 21,520,687 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34721,240,928 - 21,324,574NCBI
Celera721,453,188 - 21,539,659 (+)NCBICelera
Cytogenetic Map7p15.3NCBI
HuRef721,352,913 - 21,439,390 (+)NCBIHuRef
CHM1_1721,468,431 - 21,554,847 (+)NCBICHM1_1
T2T-CHM13v2.0721,564,221 - 21,650,967 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2721,519,001 - 21,605,471 (+)NCBI
Sp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912118,195,421 - 118,265,211 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12118,198,668 - 118,265,175 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3812118,231,686 - 118,301,440 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12118,234,933 - 118,301,440 (-)Ensemblmm10GRCm38
MGSCv3712119,473,406 - 119,539,913 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612112,460,830 - 112,527,871 (-)NCBIMGSCv36mm8
MGSCv3612118,679,035 - 118,745,471 (-)NCBIMGSCv36mm8
Cytogenetic Map12F2NCBI
cM Map1263.48NCBI
Sp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541023,955,408 - 24,015,667 (+)Ensembl
ChiLan1.0NW_00495541023,955,408 - 24,015,667 (+)NCBIChiLan1.0ChiLan1.0
SP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2626,288,720 - 26,382,933 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1774,613,443 - 74,707,660 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0722,113,013 - 22,200,012 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1721,425,584 - 21,512,238 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl721,421,259 - 21,512,238 (+)EnsemblpanPan2panpan1.1
SP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11435,367,764 - 35,444,972 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1435,367,165 - 35,442,063 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1434,910,211 - 34,987,234 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01435,292,483 - 35,369,360 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1435,292,533 - 35,369,356 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11435,411,963 - 35,488,712 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01435,111,634 - 35,188,364 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01435,445,222 - 35,521,966 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511879,604,405 - 79,667,938 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365467,279,536 - 7,344,136 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365467,279,531 - 7,342,999 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl990,337,449 - 90,410,268 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1990,337,355 - 90,410,529 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2999,754,687 - 99,827,759 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12136,748,554 - 36,832,879 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2136,747,896 - 36,831,953 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604267,744,520 - 67,830,449 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247399,170,131 - 9,235,615 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sp4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17117,836,546 - 117,894,680 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:553
Count of miRNA genes:273
Interacting mature miRNAs:339
Transcripts:ENSRNOT00000007625
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 13 82 212 91 90 59 144 59 6 459 269 22 190 107 117 31 34 34

Sequence


Ensembl Acc Id: ENSRNOT00000007625   ⟹   ENSRNOP00000007625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6145,330,416 - 145,395,146 (-)Ensembl
mRatBN7.2 Ensembl6139,192,147 - 139,252,126 (-)Ensembl
Rnor_6.0 Ensembl6146,135,877 - 146,195,819 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106494   ⟹   ENSRNOP00000096725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6145,330,416 - 145,395,146 (-)Ensembl
mRatBN7.2 Ensembl6139,192,147 - 139,251,668 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156868   ⟹   ENSRNOP00000107562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6145,330,416 - 145,395,114 (-)Ensembl
RefSeq Acc Id: NM_012761   ⟹   NP_036893
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86145,330,416 - 145,395,114 (-)NCBI
mRatBN7.26139,187,458 - 139,252,159 (-)NCBI
Rnor_6.06146,135,877 - 146,201,344 (-)NCBI
Rnor_5.06155,047,728 - 155,113,698 (-)NCBI
RGSC_v3.46145,553,512 - 145,619,389 (-)RGD
Celera6136,844,006 - 136,908,926 (-)RGD
Sequence:
RefSeq Acc Id: XM_039111794   ⟹   XP_038967722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86145,330,416 - 145,395,750 (-)NCBI
mRatBN7.26139,187,458 - 139,252,741 (-)NCBI
RefSeq Acc Id: XM_063261555   ⟹   XP_063117625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86145,330,416 - 145,395,744 (-)NCBI
RefSeq Acc Id: XM_063261556   ⟹   XP_063117626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86145,330,416 - 145,395,744 (-)NCBI
RefSeq Acc Id: NP_036893   ⟸   NM_012761
- UniProtKB: Q63158 (UniProtKB/TrEMBL),   A6KDM5 (UniProtKB/TrEMBL),   A0A8I6B4P2 (UniProtKB/TrEMBL),   F7FMI9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007625   ⟸   ENSRNOT00000007625
RefSeq Acc Id: XP_038967722   ⟸   XM_039111794
- Peptide Label: isoform X1
- UniProtKB: A0A8I6B4P2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000096725   ⟸   ENSRNOT00000106494
RefSeq Acc Id: XP_063117626   ⟸   XM_063261556
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063117625   ⟸   XM_063261555
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000107562   ⟸   ENSRNOT00000156868
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63158-F1-model_v2 AlphaFold Q63158 1-783 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3741 AgrOrtholog
BioCyc Gene G2FUF-35472 BioCyc
Ensembl Genes ENSRNOG00000005472 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007625 ENTREZGENE
  ENSRNOT00000007625.7 UniProtKB/TrEMBL
  ENSRNOT00000106494.2 UniProtKB/TrEMBL
  ENSRNOT00000156868.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Sp4-like UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:25162 UniProtKB/TrEMBL
NCBI Gene 25162 ENTREZGENE
PANTHER SP4 TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Sp4 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005472 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A8I6B4P2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LYA9_RAT UniProtKB/TrEMBL
  A0ABZ3NN46_RAT UniProtKB/TrEMBL
  A6KDM5 ENTREZGENE, UniProtKB/TrEMBL
  F7FMI9 ENTREZGENE, UniProtKB/TrEMBL
  Q63158 ENTREZGENE
UniProt Secondary Q63158 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-18 Sp4  Sp4 transcription factor  Sp4  trans-acting transcription factor 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Sp4  trans-acting transcription factor 4  Sp4  Sp4 transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Sp4  Sp4 transcription factor    Trans-acting transcription factor 4  Name updated 629478 APPROVED
2002-06-10 Sp4  Trans-acting transcription factor 4      Symbol and Name status set to approved 70586 APPROVED