Slc30a2 (solute carrier family 30 member 2)

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Gene: Slc30a2 (solute carrier family 30 member 2) Rattus norvegicus

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Symbol:

Slc30a2

Name:

solute carrier family 30 member 2

RGD ID:

3707

Description:

Enables zinc ion transmembrane transporter activity. Involved in intracellular zinc ion homeostasis and zinc ion import into zymogen granule. Predicted to be located in cytoplasmic vesicle; lysosomal membrane; and mitochondrial inner membrane. Predicted to be active in plasma membrane. Orthologous to human SLC30A2 (solute carrier family 30 member 2); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; all-trans-retinol.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

proton-coupled zinc antiporter SLC30A2; Solute carrier family 30 (zinc transporter) member 2; solute carrier family 30 (zinc transporter), member 2; solute carrier family 30, member 2; zinc transporter 2; Zink transporter 2; ZnT-2; Znt2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC30A2 (solute carrier family 30 member 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Slc30a2 (solute carrier family 30 (zinc transporter), member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc30a2 (solute carrier family 30 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC30A2 (solute carrier family 30 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC30A2 (solute carrier family 30 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc30a2 (solute carrier family 30 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC30A2 (solute carrier family 30 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC30A2 (solute carrier family 30 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc30a2 (solute carrier family 30 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	C10orf88 (chromosome 10 open reading frame 88)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SLC30A2 (solute carrier family 30 member 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc30a2 (solute carrier family 30 (zinc transporter), member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc30a2 (solute carrier family 30 member 2)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cdf-2	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ZnT33D	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ZnT35C	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc30a2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	151,843,451 - 151,855,674 (+)	NCBI		GRCr8
mRatBN7.2	5	146,559,733 - 146,571,957 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	146,559,733 - 146,571,956 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	149,261,093 - 149,273,806 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	151,031,874 - 151,044,095 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	151,017,317 - 151,030,034 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	152,559,577 - 152,571,800 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	152,559,577 - 152,571,799 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	156,356,502 - 156,368,725 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	153,086,346 - 153,098,569 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	153,097,114 - 153,107,129 (+)	NCBI
Celera	5	144,977,168 - 144,989,389 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive hypercholesterolemia (ISO)

genetic disease (ISO)

Neonatal Zinc Deficiency due to Low Breast Milk Zinc (ISO)

prostate cancer (ISO)

retinitis pigmentosa 59 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

actinomycin D (ISO)

all-trans-retinol (EXP)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

ciguatoxin CTX1B (ISO)

cobalt dichloride (EXP)

colforsin daropate hydrochloride (ISO)

copper atom (EXP)

copper(0) (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

dexamethasone (EXP,ISO)

dextran sulfate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

flavonoids (EXP)

fonofos (ISO)

hydralazine (ISO)

lead diacetate (EXP)

leflunomide (ISO)

methylmercury chloride (ISO)

mifepristone (EXP)

Muraglitazar (EXP)

N-methyl-4-phenylpyridinium (ISO)

orphenadrine (EXP)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

paraquat (ISO)

parathion (ISO)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

progesterone (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

sunitinib (ISO)

terbufos (ISO)

Tesaglitazar (EXP)

testosterone (EXP,ISO)

titanium dioxide (ISO)

triclosan (ISO)

triptonide (ISO)

troglitazone (EXP)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (EXP,ISO)

zinc dichloride (EXP,ISO)

zinc sulfate (EXP,ISO)

zinc(0) (EXP,ISO)

ziram (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular zinc ion homeostasis (IMP)

response to zinc ion (IBA)

zinc export across plasma membrane (ISO)

zinc ion import into lysosome (IEA,ISO)

zinc ion import into mitochondrion (IEA,ISO,ISS)

zinc ion import into organelle (ISO)

zinc ion import into secretory vesicle (ISO)

zinc ion import into zymogen granule (IMP)

zinc ion transmembrane transport (IBA,IEA)

zinc ion transport (IDA)

Cellular Component

cytoplasm (ISO)

cytoplasmic vesicle (IEA)

endosome membrane (ISO,ISS,TAS)

intracellular membrane-bounded organelle (ISO)

late endosome (IEA,ISO)

lysosomal membrane (IEA,ISO,ISS)

membrane (IEA)

mitochondrial inner membrane (IEA,ISO,ISS)

plasma membrane (IBA,ISO)

secretory vesicle (ISO,ISS)

transport vesicle membrane (IEA)

zymogen granule membrane (IEA,ISO,ISS)

Molecular Function

antiporter activity (IEA)

identical protein binding (IEA,ISO)

metal ion binding (IEA)

monoatomic cation transmembrane transporter activity (IEA)

protein binding (ISO)

zinc ion transmembrane transporter activity (IBA,IDA,ISO,TAS)

zinc:proton antiporter activity (IC,IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells.	Guo L, etal., Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2818-23. doi: 10.1073/pnas.0914941107. Epub 2010 Jan 27.
3.	High-level expression of zinc transporter-2 in the rat lateral and dorsal prostate.	Iguchi K, etal., J Androl 2002 Nov-Dec;23(6):819-24.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration.	Palmiter RD, etal., EMBO J 1996 Apr 15;15(8):1784-91.
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:15475177	PMID:17349999	PMID:17897319	PMID:18289514	PMID:19760107	PMID:20798384	PMID:25657003

Genomics

Comparative Map Data

Slc30a2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	151,843,451 - 151,855,674 (+)	NCBI		GRCr8
mRatBN7.2	5	146,559,733 - 146,571,957 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	146,559,733 - 146,571,956 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	149,261,093 - 149,273,806 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	151,031,874 - 151,044,095 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	151,017,317 - 151,030,034 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	152,559,577 - 152,571,800 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	152,559,577 - 152,571,799 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	156,356,502 - 156,368,725 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	153,086,346 - 153,098,569 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	153,097,114 - 153,107,129 (+)	NCBI
Celera	5	144,977,168 - 144,989,389 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

SLC30A2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	26,037,252 - 26,046,118 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	26,037,252 - 26,046,118 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	26,363,743 - 26,372,609 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	26,237,101 - 26,245,191 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	26,048,655 - 26,056,746	NCBI
Celera	1	24,761,192 - 24,769,282 (-)	NCBI		Celera
Cytogenetic Map	1	p36.11	NCBI
HuRef	1	24,618,624 - 24,626,717 (-)	NCBI		HuRef
CHM1_1	1	26,477,743 - 26,485,833 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	25,874,654 - 25,883,519 (-)	NCBI		T2T-CHM13v2.0

Slc30a2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	134,070,357 - 134,081,795 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	134,070,492 - 134,081,795 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	134,343,046 - 134,354,484 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	134,343,181 - 134,354,484 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	133,898,985 - 133,908,580 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	133,615,122 - 133,625,270 (+)	NCBI		MGSCv36	mm8
MGSCv36	4	131,918,527 - 131,928,675 (+)	NCBI		MGSCv36	mm8
Celera	4	132,522,807 - 132,532,421 (+)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	66.61	NCBI

Slc30a2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	5,504,022 - 5,516,246 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	5,507,614 - 5,515,669 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC30A2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	200,828,094 - 200,836,275 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	199,926,146 - 199,934,081 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	25,296,643 - 25,304,751 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	26,362,678 - 26,370,803 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	26,359,575 - 26,370,803 (-)	Ensembl	panpan1.1		panPan2

SLC30A2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	73,922,443 - 73,929,924 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	73,921,878 - 73,928,874 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	70,498,812 - 70,506,207 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	74,485,426 - 74,492,825 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	74,484,778 - 74,491,775 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	71,309,034 - 71,316,428 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	72,315,360 - 72,322,755 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	73,319,147 - 73,326,547 (+)	NCBI		UU_Cfam_GSD_1.0

Slc30a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	44,756,722 - 44,764,976 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	10,581,480 - 10,589,442 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	10,581,504 - 10,589,364 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC30A2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	83,477,759 - 83,484,688 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	83,478,761 - 83,484,876 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	77,113,410 - 77,122,493 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC30A2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	106,722,539 - 106,731,494 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	106,724,256 - 106,731,955 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	9,686,150 - 9,695,043 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc30a2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	10,110,740 - 10,120,093 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	10,104,622 - 10,119,953 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc30a2
120 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	372
Count of miRNA genes:	130
Interacting mature miRNAs:	143
Transcripts:	ENSRNOT00000022466, ENSRNOT00000071588
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	143608201	161165651	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	144358090	157869054	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	143799107	158428037	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	144377876	161317411	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat

Markers in Region

RH133009

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	146,571,687 - 146,571,878 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	152,571,531 - 152,571,721	NCBI	Rnor6.0
Rnor_5.0	5	156,368,456 - 156,368,646	UniSTS	Rnor5.0
RGSC_v3.4	5	153,098,300 - 153,098,490	UniSTS	RGSC3.4
Celera	5	144,989,120 - 144,989,310	UniSTS
RH 3.4 Map	5	988.4	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH140188

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	146,570,068 - 146,570,249 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	152,569,912 - 152,570,092	NCBI	Rnor6.0
Rnor_5.0	5	156,366,837 - 156,367,017	UniSTS	Rnor5.0
RGSC_v3.4	5	153,096,681 - 153,096,861	UniSTS	RGSC3.4
Celera	5	144,987,501 - 144,987,681	UniSTS
RH 3.4 Map	5	988.4	UniSTS
Cytogenetic Map	5	q36	UniSTS

PMC61071P1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	146,570,096 - 146,570,185 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	152,569,940 - 152,570,028	NCBI	Rnor6.0
Rnor_5.0	5	156,366,865 - 156,366,953	UniSTS	Rnor5.0
RGSC_v3.4	5	153,096,709 - 153,096,797	UniSTS	RGSC3.4
Celera	5	144,987,529 - 144,987,617	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3									47	9
Low		99	62	57	27	57	18	21	36	67	124	7	6
Below cutoff	18	42	138	81	42	81	18	24	151		12	50	18

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001083122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_012890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC099104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC168237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB778290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U50927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000082245 ⟹ ENSRNOP00000072908

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	146,559,733 - 146,571,956 (+)	Ensembl
Rnor_6.0 Ensembl	5	152,559,577 - 152,571,799 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113103 ⟹ ENSRNOP00000082820

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	146,559,733 - 146,571,956 (+)	Ensembl

RefSeq Acc Id:

NM_001083122 ⟹ NP_001076591

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	151,843,451 - 151,855,674 (+)	NCBI
mRatBN7.2	5	146,559,733 - 146,571,957 (+)	NCBI
Rnor_6.0	5	152,559,577 - 152,571,800 (+)	NCBI
Rnor_5.0	5	156,356,502 - 156,368,725 (+)	NCBI
RGSC_v3.4	5	153,086,346 - 153,098,569 (+)	RGD
Celera	5	144,977,168 - 144,989,389 (+)	RGD

Sequence:

show sequence

GCTGAAAGTAGAAGGTGACTGCGAGCTGCCATCGTCCCGCGCGCAACTTCGAGGGCTCACCGGG
AGAGGTGGCATGCAGACCATGGACAAGCAGAACCTGCTGGAGAGCACGCGCGGAGCCCGGTCTT
TCTTTGGAGCTCTGTGGAAGAGTGAAGCTAGCCGAATCCCGCCTGTGAACCTGCCCTCTGTTGA
ACTGGCTGTCCAGAGCAACCATTACTGTCATGCGCAGAAGGATTCTGGAAGTCACCCCAACTCC
GAGAAGCAGAGGGCCCGACGCAAACTCTATGTGGCCTCTGCCATCTGCCTGGTGTTCATGATTG
GAGAGATTATTGGTGGGTACCTGGCACAGAGCTTAGCCATCATGACCGACGCGGCCCACCTGCT
CACTGATTTCGCCAGCATGCTCATTAGTCTCTTCTCCCTCTGGGTGTCCTCCCGGCCAGCCACC
AAGACCATGAACTTCGGCTGGCAGCGAGCTGAGATCCTTGGAGCCTTGCTGTCTGTACTGTCTA
TCTGGGTGGTGACCGGGGTGCTCGTGTACCTGGCTGTACAGCGGTTGATTTCTGGAGATTATGA
GATCAAAGGGGACACCATGTTGATCACTTCGGGCTGCGCTGTGGCTGTGAACATCATAATGGGG
CTGGCCCTCCATCAGTCTGGACATGGACACAGCCATGGGCACAGCCATGAGGACAGCAGCCAGC
AGCAGCAGAACCCCAGTGTCCGAGCTGCCTTCATTCATGTGGTTGGGGACCTTCTACAGAGTGT
GGGCGTCCTGGTGGCAGCCTATATTATATACTTCAAGCCCGAGTACAAGTACGTGGACCCCATC
TGCACCTTCCTCTTCTCCATCCTGGTCTTGGGGACAACGTTAACCATCCTGAGAGATGTGATCT
TGGTTCTCATGGAAGGGACTCCCAAAGGTGTGGACTTCACAACTGTGAAAAATCTTCTGCTGTC
CGTGGATGGTGTGGAAGCCTTACACAGCCTGCATATCTGGGCGCTGACAGTGGCCCAGCCCGTG
CTGTCTGTCCACATAGCCATTGCCCAGAATGTTGATGCCCAGGCTGTGCTGAAGGTGGCTAGGG
ACCGCCTCCAGGGGAAGTTCAATTTCCACACCATGACCATCCAAATTGAGAGCTACTCTGAGGA
CATGAAGAGCTGCCAGGAGTGCCAGGGTCCCTCGGAATAACTCCCTGGCCAGACACCATCTCAT
TGGAAGTATGGCCAAGACCTGAGGGCAGAATAGTCCGTGTGCAGCCGGGACCCCAGGATCAAGA
CATGGCCTGGTCCACTACACCATGGGACTCTCCTAGGATGGGGACATAGCAGACGAGGCCCCAC
TTCTCTTTCAGGACTGTGTTTAGGCTGGATCCTGGACTAATGTTATGCTCACACCACAGCTGGA
GAGACACTGAGGCGCAGAAAGGGATTTTGGGGTGTCCTTGTATAAGCCAGGGTCTCTGTCTGAA
CCAAAAGTTGAACAAGATCCACGTGTCACGTGACTGGATAGTTGGAGCTCCCTTTAAAAGAATC
GGTCACATTGATAAAAGAGTTTTTGAACCGGAGTCAGGGGGAAGATCTGAGGATGTTTTATTAG
AATTTGGGAGAAGGAAAAAAAAAAAACAAACCCAATCACAGTCCAGGCAAGCCAAGCCGGACAT
CTCAGCAGCTGCTGAAGGAGAGGGAGGTTGGAGAGAGAGCCAGGGCTTCTGAGTTAGGGTCAGC
AGTGGAGTTCTGTAAACAGCTGGATGGTTATAATGGGGGAGCGGGTTAAAGGAACAGTGAGAGT
GTCACACACCGGCAAGCAGGTGTGCGTGCACACACGATTTAAAGACAAAAATGAAGAGAGGAAA
AGGGGGAAGGAGAAACCGGCTTCTGAGTTAGTTTGGGAAAGCGAGCTAACTTAGCGGTTAAGGT
CTATAAGCAAGTGCCTGTATGTGGGACCCCAGGGAACCATGAGTGACCTAATCAAAGAACTAAT
TGTTCCTTGGCATGTCTTTGGGTGACTGACCGGCCCAACTGAACAAACTCTGAAAGACTGCGTA
GAGGTCGGGCCGTAACTTGGTGGAATTGTTCCTCTCTGTCTTTAGGTGAATTTCTGTGATCAGT
GTCAGGTAATCAGGTCTGAGCCACCCTCGAGGGAGGGCTATGGGAGGTTGGGACAGGTTAACTC
CATCCTCACCAGGGGTAGAAAGAACCTAGTTTCCATTCTTTTGTCCAGGAGGAATTTGCTCCTA
GGGGATCCGTCTCTGATTAGCTTTACTGAACTGGGAGAAGAGCCTATGTCTTGGCTATATAACA
TGGCTTGCCAAGGCCTTGGGGACAGCATTCATACAACTGCCCCCAAGACATGAGGCCAAGGGGC
ACCTGAGGCTTCCCTCTGCCTTGCTCACTTTGACTGTTGGGCCCCAAGTGACTTCCTGGAAGAG
AAGGAGGAAGAGAGGCCTCTTCATAGGGAAAAACCTGGCTGGTTCCTTCCTGGTACCCCAGCCC
AGGAAGCCATGTCAGTGGCCTTAACAGGTGGCAGGGACAGATTCCAGTTAGCTCTTGTTCTCAT
AGCCCCAGGGCCAGGCCACTTCCCTTGACCTGTCTCAAGAGATAGAAGATCCTGCTCTGTTGCC
TAATCGACCGTGACCTTATTAGGGGTGAGGACGAGTCCAGGGGCTGACAGGAGGGGTGTCCTTG
GAGTCCATTTGAAGAATCCTTAGAGCTGGCTTGAGGTTACAGGCGCAACAGTTGAGAGATGTCC
CCAATCTTATACAGGTGACAGGCCTGCCTTCGTAGGAAGTCCTGGGCCAATGTGTACATGTTCA
TGCAGGCCAACTGGTTGTCACTTCTTAGTACCCGTGACTCACACGAAGACCAGGGACATCCTGA
CATCTCCCCCACAGGAGTGTGCAGGCAGCCCAGCCTGGTGGTTGTGTATTGGTTTCTTTGATCA
GTGTCCTGGAAAGGCTCTTGTGAAGGGCCAGACAGGCCTCCCACGTTCCTGTATTGGCTGCCCT
AGCACATAAGAGGAAAGGCTAGGTGTTGGCCTCCACCAACACCACCCAATTTTAAAAAATAAAT
GGCTAGCATTTGCTTTAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_012890 ⟹ NP_037022

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	151,844,181 - 151,855,674 (+)	NCBI
mRatBN7.2	5	146,560,463 - 146,571,957 (+)	NCBI
Rnor_6.0	5	152,560,307 - 152,571,800 (+)	NCBI
Rnor_5.0	5	156,356,502 - 156,368,725 (+)	NCBI
RGSC_v3.4	5	153,086,346 - 153,098,569 (+)	RGD
Celera	5	144,977,898 - 144,989,389 (+)	NCBI

Sequence:

show sequence

GCTCAGGGCTGCCTCCCTGCCTCCGGCCAAGCAATTTTTTCTGCCCTAACCCTGGCCTCCAGGT
CTTTCTTTGGAGCTCTGTGGAAGAGTGAAGCTAGCCGAATCCCGCCTGTGAACCTGCCCTCTGT
TGAACTGGCTGTCCAGAGCAACCATTACTGTCATGCGCAGAAGGATTCTGGAAGTCACCCCAAC
TCCGAGAAGCAGAGGGCCCGACGCAAACTCTATGTGGCCTCTGCCATCTGCCTGGTGTTCATGA
TTGGAGAGATTATTGGTGGGTACCTGGCACAGAGCTTAGCCATCATGACCGACGCGGCCCACCT
GCTCACTGATTTCGCCAGCATGCTCATTAGTCTCTTCTCCCTCTGGGTGTCCTCCCGGCCAGCC
ACCAAGACCATGAACTTCGGCTGGCAGCGAGCTGAGATCCTTGGAGCCTTGCTGTCTGTACTGT
CTATCTGGGTGGTGACCGGGGTGCTCGTGTACCTGGCTGTACAGCGGTTGATTTCTGGAGATTA
TGAGATCAAAGGGGACACCATGTTGATCACTTCGGGCTGCGCTGTGGCTGTGAACATCATAATG
GGGCTGGCCCTCCATCAGTCTGGACATGGACACAGCCATGGGCACAGCCATGAGGACAGCAGCC
AGCAGCAGCAGAACCCCAGTGTCCGAGCTGCCTTCATTCATGTGGTTGGGGACCTTCTACAGAG
TGTGGGCGTCCTGGTGGCAGCCTATATTATATACTTCAAGCCCGAGTACAAGTACGTGGACCCC
ATCTGCACCTTCCTCTTCTCCATCCTGGTCTTGGGGACAACGTTAACCATCCTGAGAGATGTGA
TCTTGGTTCTCATGGAAGGGACTCCCAAAGGTGTGGACTTCACAACTGTGAAAAATCTTCTGCT
GTCCGTGGATGGTGTGGAAGCCTTACACAGCCTGCATATCTGGGCGCTGACAGTGGCCCAGCCC
GTGCTGTCTGTCCACATAGCCATTGCCCAGAATGTTGATGCCCAGGCTGTGCTGAAGGTGGCTA
GGGACCGCCTCCAGGGGAAGTTCAATTTCCACACCATGACCATCCAAATTGAGAGCTACTCTGA
GGACATGAAGAGCTGCCAGGAGTGCCAGGGTCCCTCGGAATAACTCCCTGGCCAGACACCATCT
CATTGGAAGTATGGCCAAGACCTGAGGGCAGAATAGTCCGTGTGCAGCCGGGACCCCAGGATCA
AGACATGGCCTGGTCCACTACACCATGGGACTCTCCTAGGATGGGGACATAGCAGACGAGGCCC
CACTTCTCTTTCAGGACTGTGTTTAGGCTGGATCCTGGACTAATGTTATGCTCACACCACAGCT
GGAGAGACACTGAGGCGCAGAAAGGGATTTTGGGGTGTCCTTGTATAAGCCAGGGTCTCTGTCT
GAACCAAAAGTTGAACAAGATCCACGTGTCACGTGACTGGATAGTTGGAGCTCCCTTTAAAAGA
ATCGGTCACATTGATAAAAGAGTTTTTGAACCGGAGTCAGGGGGAAGATCTGAGGATGTTTTAT
TAGAATTTGGGAGAAGGAAAAAAAAAAAACAAACCCAATCACAGTCCAGGCAAGCCAAGCCGGA
CATCTCAGCAGCTGCTGAAGGAGAGGGAGGTTGGAGAGAGAGCCAGGGCTTCTGAGTTAGGGTC
AGCAGTGGAGTTCTGTAAACAGCTGGATGGTTATAATGGGGGAGCGGGTTAAAGGAACAGTGAG
AGTGTCACACACCGGCAAGCAGGTGTGCGTGCACACACGATTTAAAGACAAAAATGAAGAGAGG
AAAAGGGGGAAGGAGAAACCGGCTTCTGAGTTAGTTTGGGAAAGCGAGCTAACTTAGCGGTTAA
GGTCTATAAGCAAGTGCCTGTATGTGGGACCCCAGGGAACCATGAGTGACCTAATCAAAGAACT
AATTGTTCCTTGGCATGTCTTTGGGTGACTGACCGGCCCAACTGAACAAACTCTGAAAGACTGC
GTAGAGGTCGGGCCGTAACTTGGTGGAATTGTTCCTCTCTGTCTTTAGGTGAATTTCTGTGATC
AGTGTCAGGTAATCAGGTCTGAGCCACCCTCGAGGGAGGGCTATGGGAGGTTGGGACAGGTTAA
CTCCATCCTCACCAGGGGTAGAAAGAACCTAGTTTCCATTCTTTTGTCCAGGAGGAATTTGCTC
CTAGGGGATCCGTCTCTGATTAGCTTTACTGAACTGGGAGAAGAGCCTATGTCTTGGCTATATA
ACATGGCTTGCCAAGGCCTTGGGGACAGCATTCATACAACTGCCCCCAAGACATGAGGCCAAGG
GGCACCTGAGGCTTCCCTCTGCCTTGCTCACTTTGACTGTTGGGCCCCAAGTGACTTCCTGGAA
GAGAAGGAGGAAGAGAGGCCTCTTCATAGGGAAAAACCTGGCTGGTTCCTTCCTGGTACCCCAG
CCCAGGAAGCCATGTCAGTGGCCTTAACAGGTGGCAGGGACAGATTCCAGTTAGCTCTTGTTCT
CATAGCCCCAGGGCCAGGCCACTTCCCTTGACCTGTCTCAAGAGATAGAAGATCCTGCTCTGTT
GCCTAATCGACCGTGACCTTATTAGGGGTGAGGACGAGTCCAGGGGCTGACAGGAGGGGTGTCC
TTGGAGTCCATTTGAAGAATCCTTAGAGCTGGCTTGAGGTTACAGGCGCAACAGTTGAGAGATG
TCCCCAATCTTATACAGGTGACAGGCCTGCCTTCGTAGGAAGTCCTGGGCCAATGTGTACATGT
TCATGCAGGCCAACTGGTTGTCACTTCTTAGTACCCGTGACTCACACGAAGACCAGGGACATCC
TGACATCTCCCCCACAGGAGTGTGCAGGCAGCCCAGCCTGGTGGTTGTGTATTGGTTTCTTTGA
TCAGTGTCCTGGAAAGGCTCTTGTGAAGGGCCAGACAGGCCTCCCACGTTCCTGTATTGGCTGC
CCTAGCACATAAGAGGAAAGGCTAGGTGTTGGCCTCCACCAACACCACCCAATTTTAAAAAATA
AATGGCTAGCATTTGCTTTAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001076591	(Get FASTA)	NCBI Sequence Viewer
	NP_037022	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB02775	(Get FASTA)	NCBI Sequence Viewer
	AAH61997	(Get FASTA)	NCBI Sequence Viewer
	AAI68237	(Get FASTA)	NCBI Sequence Viewer
	EDL80718	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072908.1
	ENSRNOP00000082820.1
GenBank Protein	Q62941	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_037022 ⟸ NM_012890
- Peptide Label:	isoform 2
- UniProtKB:	Q62941 (UniProtKB/Swiss-Prot), Q6P6V5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASRSFFGALWKSEASRIPPVNLPSVELAVQSNHYCHAQKDSGSHPNSEKQRARRKLYVASAIC LVFMIGEIIGGYLAQSLAIMTDAAHLLTDFASMLISLFSLWVSSRPATKTMNFGWQRAEILGAL LSVLSIWVVTGVLVYLAVQRLISGDYEIKGDTMLITSGCAVAVNIIMGLALHQSGHGHSHGHSH EDSSQQQQNPSVRAAFIHVVGDLLQSVGVLVAAYIIYFKPEYKYVDPICTFLFSILVLGTTLTI LRDVILVLMEGTPKGVDFTTVKNLLLSVDGVEALHSLHIWALTVAQPVLSVHIAIAQNVDAQAV LKVARDRLQGKFNFHTMTIQIESYSEDMKSCQECQGPSE hide sequence

RefSeq Acc Id:	NP_001076591 ⟸ NM_001083122
- Peptide Label:	isoform 1
- UniProtKB:	B4F7D8 (UniProtKB/TrEMBL), Q6P6V5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQTMDKQNLLESTRGARSFFGALWKSEASRIPPVNLPSVELAVQSNHYCHAQKDSGSHPNSEKQ RARRKLYVASAICLVFMIGEIIGGYLAQSLAIMTDAAHLLTDFASMLISLFSLWVSSRPATKTM NFGWQRAEILGALLSVLSIWVVTGVLVYLAVQRLISGDYEIKGDTMLITSGCAVAVNIIMGLAL HQSGHGHSHGHSHEDSSQQQQNPSVRAAFIHVVGDLLQSVGVLVAAYIIYFKPEYKYVDPICTF LFSILVLGTTLTILRDVILVLMEGTPKGVDFTTVKNLLLSVDGVEALHSLHIWALTVAQPVLSV HIAIAQNVDAQAVLKVARDRLQGKFNFHTMTIQIESYSEDMKSCQECQGPSE hide sequence

Ensembl Acc Id:

ENSRNOP00000072908 ⟸ ENSRNOT00000082245

Ensembl Acc Id:

ENSRNOP00000082820 ⟸ ENSRNOT00000113103

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q62941-F1-model_v2	AlphaFold	Q62941	1-359	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694135

Promoter ID:

EPDNEW_R4660

Type:

initiation region

Name:

Slc30a2_1

Description:

solute carrier family 30 member 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	152,559,538 - 152,559,598	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3707	AgrOrtholog
BioCyc Gene	G2FUF-39581	BioCyc
Ensembl Genes	ENSRNOG00000054142	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000082245.2	UniProtKB/TrEMBL
	ENSRNOT00000113103.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1510.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5599697	IMAGE-MGC_LOAD
InterPro	Cation_efflux	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cation_efflux_CTD_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cation_efflux_TMD_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CDF/SLC30A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25362	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:72511	IMAGE-MGC_LOAD
NCBI Gene	25362	ENTREZGENE
PANTHER	CATION EFFLUX PROTEIN/ ZINC TRANSPORTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC TRANSPORTER 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Cation_efflux	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Slc30a2	PhenoGen
RatGTEx	ENSRNOG00000054142	RatGTEx
Superfamily-SCOP	SSF160240	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF161111	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC222341
UniProt	A0A8I5ZUT9_RAT	UniProtKB/TrEMBL
	A6IT17_RAT	UniProtKB/TrEMBL
	B4F7D8	ENTREZGENE, UniProtKB/TrEMBL
	Q62941	ENTREZGENE
	Q6P6V5	ENTREZGENE, UniProtKB/TrEMBL
	ZNT2_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-09	Slc30a2	solute carrier family 30 member 2	Slc30a2	solute carrier family 30 (zinc transporter), member 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Slc30a2	solute carrier family 30 (zinc transporter), member 2		solute carrier family 30, member 2	Name updated	1299863	APPROVED
2003-04-09	Slc30a2	solute carrier family 30, member 2		Solute carrier family 30 (zinc transporter), member 2	Name updated	629478	APPROVED
2001-06-22	Znt2	Zink transporter 2			Symbol withdrawn, duplicate of Slc30a2 (RGD:3707)	67952	WITHDRAWN
2001-06-22	Slc30a2	Solute carrier family 30 (zinc transporter), member 3			Name updated	67952	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized on vesicles	730024
gene_expression	highly expressed in lateral and dorsal prostate gland; expression level is not affected by castration	1299032
gene_process	facilitates zinc transport into endosomal/lysosomal compartments, which may serve to protect cells from zinc toxicity	730024
gene_protein	359 amino acids	730024

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM