Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | decreases expression | ISO | St8sia1 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of ST8SIA1 mRNA | CTD | PMID:26682919 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | ST8SIA1 (Homo sapiens) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ST8SIA1 mRNA | CTD | PMID:19684285 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | St8sia1 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of ST8SIA1 mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | St8sia1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ST8SIA1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | St8sia1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ST8SIA1 mRNA | CTD | PMID:19933214 and PMID:20159946 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ST8SIA1 mRNA | CTD | PMID:19684285 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of ST8SIA1 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of ST8SIA1 mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ST8SIA1 exon and Aflatoxin B1 results in decreased methylation of ST8SIA1 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | ST8SIA1 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of ST8SIA1 intron | CTD | PMID:30157460 | alpha-Zearalanol | increases expression | EXP | | 6480464 | Zeranol results in increased expression of ST8SIA1 mRNA | CTD | PMID:35163327 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ST8SIA1 mRNA | CTD | PMID:16483693 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of ST8SIA1 mRNA | CTD | PMID:30779732 | benzo[a]pyrene | increases methylation | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ST8SIA1 5' UTR and Benzo(a)pyrene results in increased methylation of ST8SIA1 promoter | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | ST8SIA1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of ST8SIA1 intron | CTD | PMID:30157460 | beta-naphthoflavone | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ST8SIA1 mRNA | CTD | PMID:18164116 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of ST8SIA1 mRNA | CTD | PMID:31163220 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ST8SIA1 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | St8sia1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ST8SIA1 mRNA | CTD | PMID:35598803 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ST8SIA1 mRNA | CTD | PMID:30816183 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of ST8SIA1 mRNA | CTD | PMID:32479839 | buta-1,3-diene | decreases expression | ISO | St8sia1 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of ST8SIA1 mRNA | CTD | PMID:29038090 | calcitriol | increases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of ST8SIA1 mRNA | CTD | PMID:16002434 | carmustine | increases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Carmustine results in increased expression of ST8SIA1 mRNA | CTD | PMID:15980968 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of ST8SIA1 mRNA | CTD | PMID:26577399 | cycloheximide | multiple interactions | ISO | ST8SIA1 (Homo sapiens) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ST8SIA1 mRNA | CTD | PMID:19684285 | cycloheximide | increases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Cycloheximide results in increased expression of ST8SIA1 mRNA | CTD | PMID:19684285 | DDT | increases methylation | EXP | | 6480464 | DDT results in increased methylation of ST8SIA1 gene | CTD | PMID:30207508 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of ST8SIA1 mRNA | CTD | PMID:23914054 | diquat | decreases expression | ISO | St8sia1 (Mus musculus) | 6480464 | Diquat results in decreased expression of ST8SIA1 mRNA | CTD | PMID:36851058 | dorsomorphin | multiple interactions | ISO | ST8SIA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ST8SIA1 mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | St8sia1 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of ST8SIA1 mRNA | CTD | PMID:36227756 | emodin | increases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Emodin results in increased expression of ST8SIA1 mRNA | CTD | PMID:16045814 | malathion | increases expression | EXP | | 6480464 | Malathion results in increased expression of ST8SIA1 mRNA | CTD | PMID:19784758 | methapyrilene | increases methylation | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of ST8SIA1 intron | CTD | PMID:30157460 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ST8SIA1 gene | CTD | PMID:35440735 | miglustat | multiple interactions | ISO | St8sia1 (Mus musculus) | 6480464 | miglustat inhibits the reaction [[ST8SIA1 protein affects the abundance of Gangliosides] which results in decreased expression of PAWR protein] and miglustat inhibits the reaction [ST8SIA1 protein results in increased expression of BCL2 protein] | CTD | PMID:11574545 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of ST8SIA1 gene | CTD | PMID:33148267 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ST8SIA1 mRNA | CTD | PMID:18164116 | nickel atom | increases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Nickel results in increased expression of ST8SIA1 mRNA | CTD | PMID:25583101 | nitrobenzenes | increases expression | EXP | | 6480464 | Nitrobenzenes analog results in increased expression of ST8SIA1 mRNA | CTD | PMID:19784758 | ozone | multiple interactions | ISO | St8sia1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ST8SIA1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ST8SIA1 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ST8SIA1 mRNA | CTD | PMID:19784758 and PMID:30723492 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ST8SIA1 mRNA | CTD | PMID:19784758 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of ST8SIA1 gene | CTD | PMID:33148267 | progesterone | decreases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Progesterone results in decreased expression of ST8SIA1 mRNA | CTD | PMID:20864642 | SB 431542 | multiple interactions | ISO | ST8SIA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ST8SIA1 mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ST8SIA1 mRNA | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | St8sia1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of ST8SIA1 mRNA | CTD | PMID:25270620 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ST8SIA1 mRNA | CTD | PMID:19784758 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ST8SIA1 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ST8SIA1 mRNA | CTD | PMID:24935251 | triphenyl phosphate | decreases expression | EXP | | 6480464 | triphenyl phosphate results in decreased expression of ST8SIA1 mRNA | CTD | PMID:30589522 | valproic acid | decreases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ST8SIA1 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ST8SIA1 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ST8SIA1 mRNA | CTD | PMID:26272509 | valproic acid | multiple interactions | ISO | ST8SIA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ST8SIA1 mRNA | CTD | PMID:27188386 | zearalenone | decreases expression | ISO | ST8SIA1 (Homo sapiens) | 6480464 | Zearalenone results in decreased expression of ST8SIA1 mRNA | CTD | PMID:36828454 | |