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Gene: Padi2 (peptidyl arginine deiminase 2) Rattus norvegicus

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Symbol:

Padi2

Name:

peptidyl arginine deiminase 2

RGD ID:

3288

Description:

Enables protein-arginine deiminase activity. Predicted to be involved in several processes, including estrogen receptor signaling pathway; negative regulation of chemokine-mediated signaling pathway; and transcription initiation-coupled chromatin remodeling. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in euchromatin. Predicted to be active in cytoplasm and nucleus. Orthologous to human PADI2 (peptidyl arginine deiminase 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Pdi2; peptidyl arginine deiminase type II; peptidyl arginine deiminase, type 2; peptidyl arginine deiminase, type II; peptidylarginine deiminase II; protein-arginine deiminase type II; protein-arginine deiminase type-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PADI2 (peptidyl arginine deiminase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Padi2 (peptidyl arginine deiminase, type II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Padi2 (peptidyl arginine deiminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PADI2 (peptidyl arginine deiminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PADI2 (peptidyl arginine deiminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Padi2 (peptidyl arginine deiminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PADI2 (peptidyl arginine deiminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PADI2 (peptidyl arginine deiminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Padi2 (peptidyl arginine deiminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Padi2 (peptidyl arginine deiminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	STX11 (syntaxin 11)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Padi2 (peptidyl arginine deiminase, type II)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Padi2 (peptidyl arginine deiminase, type II)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PADI2 (peptidyl arginine deiminase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PADI2 (peptidyl arginine deiminase 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	padi2 (peptidyl arginine deiminase, type II)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	padi2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	padi2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	creb1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	158,492,087 - 158,534,662 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	158,492,066 - 158,534,662 (+)	Ensembl				GRCr8
mRatBN7.2	5	153,209,053 - 153,251,632 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	153,209,053 - 153,251,632 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	155,898,744 - 155,940,735 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	157,672,018 - 157,714,009 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	157,661,096 - 157,703,184 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	159,428,479 - 159,471,113 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	159,428,515 - 159,471,144 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	163,141,202 - 163,183,775 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	159,762,824 - 159,805,399 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	151,567,606 - 151,616,600 (+)	NCBI		Celera
RGSC_v3.1	5	159,773,011 - 159,815,587 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

rheumatoid arthritis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-acetamidofluorene (ISO)

4,4'-sulfonyldiphenol (ISO)

4-phenylbutyric acid (ISO)

6-propyl-2-thiouracil (EXP)

afimoxifene (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

bisphenol F (ISO)

Brodifacoum (EXP)

buta-1,3-diene (ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

copper atom (EXP)

copper(0) (EXP)

crocidolite asbestos (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

diethylstilbestrol (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

ethanol (ISO)

finasteride (EXP)

flutamide (EXP)

fonofos (ISO)

formaldehyde (ISO)

furan (EXP)

genistein (ISO)

glycidol (EXP)

glyphosate (EXP)

GW 4064 (ISO)

hydrogen peroxide (ISO)

lead(0) (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

methimazole (EXP)

methoxychlor (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (ISO)

nickel atom (ISO)

nitrofen (EXP)

O-methyleugenol (ISO)

okadaic acid (ISO)

paclitaxel (ISO)

paracetamol (EXP)

parathion (ISO)

pentanal (ISO)

perfluorohexanesulfonic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

propanal (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

succimer (ISO)

sulfadimethoxine (EXP)

tamoxifen (ISO)

terbufos (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (ISO)

chromatin remodeling (IBA)

estrogen receptor signaling pathway (ISO)

negative regulation of chemokine-mediated signaling pathway (ISO)

negative regulation of lymphocyte chemotaxis (ISO)

substantia nigra development (ISO)

transcription initiation-coupled chromatin remodeling (ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO)

euchromatin (ISO)

nucleus (IBA)

Molecular Function

calcium ion binding (IEA)

histone arginine deiminase activity (IBA)

histone H3R26 arginine deiminase activity (ISO)

hydrolase activity (IEA)

metal ion binding (IEA)

nuclear estrogen receptor binding (ISO)

protein homodimerization activity (ISO,ISS)

protein-arginine deiminase activity (IDA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin.	Ishigami A, etal., Arch Biochem Biophys. 2002 Nov 1;407(1):25-31.
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
7.	Isolation and characterization of cDNA clones encoding rat skeletal muscle peptidylarginine deiminase.	Watanabe K and Senshu T, J Biol Chem 1989 Sep 15;264(26):15255-60.

Additional References at PubMed

PMID:1601308	PMID:15629448	PMID:17579814	PMID:18248664	PMID:18645041	PMID:19056867	PMID:19085382	PMID:19641855	PMID:20439489	PMID:22853951	PMID:22926577	PMID:25621824

Genomics

Comparative Map Data

Padi2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	158,492,087 - 158,534,662 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	158,492,066 - 158,534,662 (+)	Ensembl				GRCr8
mRatBN7.2	5	153,209,053 - 153,251,632 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	153,209,053 - 153,251,632 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	155,898,744 - 155,940,735 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	157,672,018 - 157,714,009 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	157,661,096 - 157,703,184 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	159,428,479 - 159,471,113 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	159,428,515 - 159,471,144 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	163,141,202 - 163,183,775 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	159,762,824 - 159,805,399 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	151,567,606 - 151,616,600 (+)	NCBI		Celera
RGSC_v3.1	5	159,773,011 - 159,815,587 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

PADI2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	17,066,761 - 17,119,451 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	17,066,761 - 17,119,459 (-)	Ensembl			hg38	GRCh38
GRCh37	1	17,393,256 - 17,445,946 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	17,265,843 - 17,318,535 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	17,140,558 - 17,191,236	NCBI
Celera	1	15,715,602 - 15,768,303 (-)	NCBI		Celera
Cytogenetic Map	1	p36.13	NCBI
HuRef	1	15,637,268 - 15,689,337 (-)	NCBI		HuRef
CHM1_1	1	17,501,602 - 17,554,329 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	16,877,198 - 16,929,905 (-)	NCBI		T2T-CHM13v2.0

Padi2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	140,633,685 - 140,679,897 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	140,633,655 - 140,679,897 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	140,906,336 - 140,952,586 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	140,906,344 - 140,952,586 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	140,462,275 - 140,508,501 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	138,644,091 - 138,693,178 (+)	NCBI		MGSCv36	mm8
MGSCv36	4	140,178,503 - 140,224,662 (+)	NCBI		MGSCv36	mm8
Celera	4	142,714,994 - 142,753,117 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	73.01	NCBI

Padi2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955527	1,709,444 - 1,752,783 (+)	Ensembl
ChiLan1.0	NW_004955527	1,709,307 - 1,751,332 (+)	NCBI	ChiLan1.0	ChiLan1.0

PADI2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	210,009,732 - 210,062,423 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	209,128,609 - 209,181,304 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	16,011,708 - 16,064,344 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	17,067,729 - 17,120,513 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	17,067,729 - 17,120,513 (-)	Ensembl			panPan2	panpan1.1

PADI2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	81,116,031 - 81,147,889 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	81,116,140 - 81,145,043 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	77,641,018 - 77,685,332 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	81,749,888 - 81,794,334 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	81,749,859 - 81,794,317 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	78,502,939 - 78,547,380 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	79,519,889 - 79,564,357 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	80,588,375 - 80,632,825 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Padi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	38,210,290 - 38,236,848 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	4,033,230 - 4,088,256 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	4,033,703 - 4,066,468 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PADI2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	75,696,481 - 75,755,890 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	75,696,476 - 75,755,977 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	70,039,608 - 70,099,180 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PADI2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	115,465,098 - 115,520,772 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	115,465,338 - 115,520,828 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666033	596,810 - 650,559 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Padi2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	2,693,060 - 2,734,107 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624764	2,693,276 - 2,734,070 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Padi2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	17,197,990 - 17,240,361 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Padi2
373 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	132
Count of miRNA genes:	90
Interacting mature miRNAs:	107
Transcripts:	ENSRNOT00000010183
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	116702075	161702075	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149642129	171146538	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	156396728	172190305	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	149805999	162987697	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138002522	170842766	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	148093485	172129029	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	156396728	167181764	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	114131300	159131300	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	149661912	166600247	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	116702075	161702075	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	116702075	161702075	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	116702075	161702075	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	156289283	171137955	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	114131300	159131300	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat

Markers in Region

RH128094

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	158,534,420 - 158,534,616 (+)	Marker Load Pipeline
mRatBN7.2	5	153,251,389 - 153,251,585 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	159,470,862 - 159,471,057	NCBI	Rnor6.0
Rnor_5.0	5	163,183,533 - 163,183,728	UniSTS	Rnor5.0
RGSC_v3.4	5	159,805,157 - 159,805,352	UniSTS	RGSC3.4
Celera	5	151,616,358 - 151,616,553	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH132527

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	158,505,861 - 158,506,588 (+)	Marker Load Pipeline
mRatBN7.2	5	153,222,829 - 153,223,556 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	159,442,304 - 159,443,030	NCBI	Rnor6.0
Rnor_5.0	5	163,154,977 - 163,155,703	UniSTS	Rnor5.0
RGSC_v3.4	5	159,776,599 - 159,777,325	UniSTS	RGSC3.4
Celera	5	151,581,380 - 151,582,106	UniSTS
RH 3.4 Map	5	1051.3	UniSTS
Cytogenetic Map	5	q36	UniSTS

BF386039

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	153,207,243 - 153,207,417 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	159,426,720 - 159,426,893	NCBI	Rnor6.0
Rnor_5.0	5	163,139,393 - 163,139,566	UniSTS	Rnor5.0
RGSC_v3.4	5	159,761,015 - 159,761,188	UniSTS	RGSC3.4
Celera	5	151,565,797 - 151,565,970	UniSTS
RH 3.4 Map	5	1052.9	UniSTS
Cytogenetic Map	5	q36	UniSTS

BI297266

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	153,224,951 - 153,225,115 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	159,444,426 - 159,444,589	NCBI	Rnor6.0
Rnor_5.0	5	163,157,099 - 163,157,262	UniSTS	Rnor5.0
RGSC_v3.4	5	159,778,721 - 159,778,884	UniSTS	RGSC3.4
Celera	5	151,583,502 - 151,583,665	UniSTS
RH 3.4 Map	5	1053.1	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	86	59	6	350	186	11	142	81	92	31	16	16

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017226	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC114436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC134642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D10459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	J05022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010183 ⟹ ENSRNOP00000010183

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	158,492,066 - 158,534,662 (+)	Ensembl
mRatBN7.2 Ensembl	5	153,209,053 - 153,251,632 (+)	Ensembl
Rnor_6.0 Ensembl	5	159,428,515 - 159,471,144 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000159478 ⟹ ENSRNOP00000111673

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	158,492,066 - 158,534,662 (+)	Ensembl

RefSeq Acc Id:

NM_017226 ⟹ NP_058922

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	158,492,087 - 158,534,662 (+)	NCBI
mRatBN7.2	5	153,209,053 - 153,251,632 (+)	NCBI
Rnor_6.0	5	159,428,529 - 159,471,104 (+)	NCBI
Rnor_5.0	5	163,141,202 - 163,183,775 (+)	NCBI
RGSC_v3.4	5	159,762,824 - 159,805,399 (+)	RGD
Celera	5	151,567,606 - 151,616,600 (+)	RGD

Sequence:

show sequence

CCTGTAGCAGGTGCTCATTCCCGGGAGCAGCGCGGACTGCAGCCGCCTCTGCGGGGAAAGATGC
TGCGGGAGCGGACCGTACGGCTGCAATACGGGAGCCGCGTGGAGGCGGTGTACGTGCTGGGCAC
GCAGCTCTGGACCGATGTCTACAGTGCAGCGCCTGCTGGGGCCAAAACCTTCAGCCTGAAGCAC
TCGGAGGGTGTGAAAGTAGAGGTCGTGCGCGATGGAGAGGCAGAGGAGGTAGTCACCAACGGCA
AGCAGCGTTGGGCCCTGTCACCCAGCACCACACTGCGACTCAGCATGGCCCAGGCCAGCACCGA
GGCCAGCAGCGACAAGGTCACCGTCAACTACTATGAAGAGGATGGCAGTGCCCCTATTGACCAG
GCTGGGCTCTTCCTCACTGCCATTGAGATCTCACTGGATGTGGACGCAGACCGGGACGGAGAAG
TGGAGAAGAATAATCCTAAGAAGGCATCCTGGACCTGGGGTCCTGAGGGCCAGGGGGCCATCCT
GCTGGTGAACTGTGACCGAGACACACCCTGGTTGCCCAAGGAGGACTGCAGTGATGAAAAGGTC
TACAGCAAACAAGACCTTCAGGACATGTCTCAGATGATCCTGAGGACCAAAGGCCCTGACCGCC
TGCCCGCCGGGTATGAAATAGTCCTCTACATTTCTATGTCGGACTCGGACAAAGTGGGCGTGTT
CTACGTGGAGAACCCGTTCTTTGGCCAGCGCTACATCCACATCCTGGGCCGGCAGAAGCTCTAC
CACGTGGTGAAGTACACCGGTGGCTCTGCAGAGTTGCTGTTCTTCGTGGAAGGCCTCCGTTTCC
CAGACGAGAGTTTCTCAGGCCTGGTTTCCATCCACGTCAGTCTGCTGGAGTATATGGCCGAGGA
CATCCCATTGACACCCATCTTCACAGACACCGTGACGTTCCGGATTGCCCCATGGATTATGACA
CCCAACATCCTGCCTCCCGTGTCAGTGTTTGTGTGCTGCATGAAGGACAATTACCTGTTCCTGA
AAGAGGTGAAGAACCTGGTGGAGAAAACCAACTGCGAGCTGAAAGTTTGTTTCCAGTACATGAA
TCGTGGCGACCGCTGGATCCAGGATGAAATTGAGTTTGGCTACATTGAGGCACCTCACAAAGGC
TTCCCAGTAGTGCTGGACTCCCCTCGAGATGGAAACCTGAAGGACTTCCCCATTAAGCAACTCC
TGGGCCCAGATTTCGGCTATGTGACCCGGGAGCCCCTCTTTGAGACTGTCACCAGCCTTGACTC
CTTCGGGAATCTGGAGGTCAGTCCCCCAGTGACCGTGAATGGCAAGGCATACCCGCTTGGCCGG
ATCCTCATCGGGAGCAGTTTCCCTCTGTCTGGAGGCAGGAGGATGACCAAGGTGGTGCGTGACT
TCCTGCAGGCCCAGCAGGTGCAGGCGCCCGTGGAACTCTACTCGGATTGGCTGACTGTGGGCCA
CGTCGATGAGTTCATGACCTTCGTCCCCATCCCAGGCAAAAAGGAATTTCGGCTGCTCATGGCC
AGCACCTCAGCCTGCTACCAGCTCTTCAGAGAAAAGCAGAAGGAAGGCCACGGGGAGGCCATTA
TGTTCAAGGGTCTGGGGGGCATGAGCAGCAAACGAATCACCATCAATAAGATCCTGTCCAATGA
GAGCCTCACGCAGGAAAACCAGTACTTTCAGCGCTGTCTGGATTGGAACCGTGACATCCTTAAG
AAGGAGCTGGCTCTGACTGAGAAGGACATCATTGACCTGCCTGCTCTCTTCAAGATGGATGAAG
ACCGTCAGGCCAGGGCTTTCTTCCCTAACATGGTGAACATGATCGTGCTAGACAAGGACCTGGG
TATCCCCAAGCCTTTCGGGCCCCAGGTCGAGGAGGAGTGCTGCCTGGAGACACATGTTCGAGGC
CTGCTGGAGCCCCTGGGCCTTGCCTGCACCTTCATTGATGACATCTCTGCATACCACAAGTTTC
TGGGAGAGGTTCACTGTGGCACCAACGTGCGCAGGAAGCCCTTCACCTTCAAGTGGTGGCACAT
GGTGCCCTGACTGCCAGGGGCCCTGGCCTTCCTTCCTTCCCTGCGATCTCCAGGTCCTTCCTGT
GTCCCCAAGTCCTTCCCCTACAAGAAGCGGGTGGGATTGGGATTGTGCCTTGCTGTCCCCTGGA
GAAGGACTTTAGTGTCCATTGAAGCCACCCCGAGTAAGTCCAACCGTTCCCTACCCCTGAAAAT
AGCTAGACATGTGGTTAGTGTGCAGAACTTTGGAAGGGAAAACCAGACTTCAACAAATCATGTA
GTCGCACTGTCCCCCAAAGAATTCTCAGCCTCTACTCCAGATCAGAAGGAGGGGAGAGAGAAGG
GAGACTCTGAGGTCATTGGCTCGCCCAGCACCCATCTGACATTCAAGATAGACCAGGAGGACCA
GGGCCAGGGTCCTGGCGTACCTCGGATGGTACCATCTTTTCAAGCTTACCTACCTTGGGGCCTC
CTGGTCGGATCCTTCGCCCATTCATTCCTTAAGGCTTCCCATACACACTGTGTCCCCACCCCAC
CCCCACCCCCTGAGGGTCCAATCATTCAGCTTAGAATCATCCGGAAATGGGTCTTAGCAGAGGA
GAGGTCTTCACTTTCTGTGGATTCGGGCTGCCCAATTTTGGGAGGACGGGGAGGTCTCGGACTA
GCATCCGATGTCCAAAGTTCAGTAGACAAAGATGCACCTGTGTATCGACACTATTTCTGTTCTC
TCCCCCGGTCCTCAGTTCTCTGGCCAGTCCGTGAGCCTCTCTTTCCATTGTTCTTCTGTTTCTG
ACACTGGCCTTCCTATTCTGGATGTTGCCCCTCCAGCAGCTACAGTTTCTTCACCACCAGCCAG
ATTCAGGCCTCCCGAGGGCCTGAGAAGTAGCCAATCCCACTGTCCAAGGATGCTGAGGATGCTG
GCAATGCCCCAGCCTCACTGATCACTTCCCGGCTAGCTACTGCTCCAGAGGCAGAATTTTCCAG
CACACTTTCCGAAGGCCTTCCATCCAGATACAGGCAAATGGATCCCCCCTCCCCCAACCTGCTT
CATTTAGAAAGGCCTCCAGGAGCTGTAGAGATGGCTCGGCAGTTAAAAATGCTCCCTGCTCTTC
AAGGGGACCCAAGTTCAGTTCCCAACACCCACGGTGCTCTGTAACTCCAGATCCAGAGGATCCA
ATACCCTTTTCTGGTCTCTGAGGGCACTTCACGCATGTGCACAAACCCATAGACATAAATCAAT
GTTTGAGAGTCTGGAGAGATGGCCCAGTGGTTAAAAGCACTTGCTGCTCTTGCGGAGGACCTGG
GTTCAGTTCTCAGCACCCAGTTGGTGGCTCACAACCAACTATAACTCTAGTCCCAGGGGGTCCG
ATGCTCTCCTCTGACCTCCATAGGCTTCTGCACACAGGTGGTTCACATACACACCCTCAAGCAC
ACATACAAGTAAAGTAAAGTAAACGATGCTTAAAAAATAGAAACAAGGAAAATATGTCTCTTAA
AATAGAGAAGGTCCTTTTAAGGCCAAGAAGGTAGGAAATGGTAATTCTGCTTTGGAGGGTTAAA
CGGTCCCATTTTATAGCTGAAGAAAAGGGTTACACCCACATTCTTAGGGGAACAAGATTTTTAC
CTTGCATTATTTCCTCAGTAGGTTGTATGCTACTGAGTAGTGGGCACAGACTTGGACGCTGATA
ACACAAGCTAGCCATAGACTCGCTTGTCCCAACAGACAAAACCCACGTCTGCATAGCCACCCTC
CGCCCTTGCTGTGGTAACACTACCCAGTATATTCAAGAAGCATTCAGGACAACAGTCACTGCCT
TCAACAATTAGGAGGTGTCCTCTTTTCTGTCCAGCTGGCCTAATGCACCATGCCAGGTCAGGCC
CCAGAGCCTCCAAAGCTGTCATCCTCTGTCTCTGGGGACAGAGGTTCCTGCCCTTGAGGGCAAA
GCCCCAAATCCTGTCTCCTGCTCCAGAGTGGAAAACACAGGCACCTCTCTGAGGGAGGTGGTCT
GGGGATGTGGCGGTTTGTCGTGTGTGGTGTTCCGTTAAAGTGGCTTTTACTGCTTTTATTTTTA
TCTGCGTTAAGAGGAAGTGAGCCCTCCCCACGTGGAGGCCACGACGTGTCTTTTGTAGGTTGTG
TTGGTGTTTGGGGAATTTCTGGAACTCCAGGACTCCGCCTGTCCCATCTCACTTACTCACCCAG
TGTGACCCCCTCAAGTGTGGACGCCCCATCCCGAGGACTCCTTGCTCTTCTCCACCTCCATTGT
TTGTTGGTGTTTTTTTTTTTTAAACTTATGCCCAGAGGCTTCTGGGCTATGCCAGTTCCTGTTT
CAATGTTAATTTTGAAATGCTCTGCTGAGGGTGGGGGTAACGGCAGGAAGATGGCGGGAATGGG
GCAGTATGAACTTCCTGGAAAAAAAGCCAAGATGGAGTCTGAGGAGTGTCTGGGGGAAGAGCCA
AAATAAAGAGCAATAAAATAAGCCGTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_058922	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41793	(Get FASTA)	NCBI Sequence Viewer
	BAA01253	(Get FASTA)	NCBI Sequence Viewer
	EDL80949	(Get FASTA)	NCBI Sequence Viewer
	EDL80950	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010183
GenBank Protein	P20717	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_058922 ⟸ NM_017226

- UniProtKB:

P20717 (UniProtKB/Swiss-Prot), A6ITP8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAKTFSLKHSEGVKVEVVRDGEAEEVVTN
GKQRWALSPSTTLRLSMAQASTEASSDKVTVNYYEEDGSAPIDQAGLFLTAIEISLDVDADRDG
EVEKNNPKKASWTWGPEGQGAILLVNCDRDTPWLPKEDCSDEKVYSKQDLQDMSQMILRTKGPD
RLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRQKLYHVVKYTGGSAELLFFVEGLR
FPDESFSGLVSIHVSLLEYMAEDIPLTPIFTDTVTFRIAPWIMTPNILPPVSVFVCCMKDNYLF
LKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPIKQ
LLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVNGKAYPLGRILIGSSFPLSGGRRMTKVVR
DFLQAQQVQAPVELYSDWLTVGHVDEFMTFVPIPGKKEFRLLMASTSACYQLFREKQKEGHGEA
IMFKGLGGMSSKRITINKILSNESLTQENQYFQRCLDWNRDILKKELALTEKDIIDLPALFKMD
EDRQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLETHVRGLLEPLGLACTFIDDISAYHK
FLGEVHCGTNVRRKPFTFKWWHMVP

hide sequence

Ensembl Acc Id:

ENSRNOP00000010183 ⟸ ENSRNOT00000010183

Ensembl Acc Id:

ENSRNOP00000111673 ⟸ ENSRNOT00000159478

Protein Domains

Protein-arginine deiminase (PAD) central Protein-arginine deiminase (PAD) N-terminal Protein-arginine deiminase C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P20717-F1-model_v2	AlphaFold	P20717	1-665	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694214

Promoter ID:

EPDNEW_R4738

Type:

single initiation site

Name:

Padi2_1

Description:

peptidyl arginine deiminase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	159,428,508 - 159,428,568	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3288	AgrOrtholog
BioCyc Gene	G2FUF-39376	BioCyc
BioCyc Pathway	PWY-4921 [protein citrullination]	BioCyc
BioCyc Pathway Image	PWY-4921	BioCyc
Ensembl Genes	ENSRNOG00000007574	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000010183	ENTREZGENE
Gene3D-CATH	2.60.40.1700	UniProtKB/Swiss-Prot
	2.60.40.1860	UniProtKB/Swiss-Prot
	L-arginine/glycine Amidinotransferase, Chain A	UniProtKB/Swiss-Prot
InterPro	Cupredoxin	UniProtKB/Swiss-Prot
	PAD	UniProtKB/Swiss-Prot
	PAD_C	UniProtKB/Swiss-Prot
	PAD_central_sf	UniProtKB/Swiss-Prot
	PAD_N	UniProtKB/Swiss-Prot
	PAD_N_sf	UniProtKB/Swiss-Prot
	Prot_Arg_deaminase_cen_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:29511	UniProtKB/Swiss-Prot
NCBI Gene	29511	ENTREZGENE
PANTHER	PROTEIN-ARGININE DEIMINASE TYPE-2	UniProtKB/Swiss-Prot
	PTHR10837	UniProtKB/Swiss-Prot
Pfam	PAD	UniProtKB/Swiss-Prot
	PAD_M	UniProtKB/Swiss-Prot
	PAD_N	UniProtKB/Swiss-Prot
PhenoGen	Padi2	PhenoGen
PIRSF	Protein-arginine_deiminase	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000007574	RatGTEx
Superfamily-SCOP	Pentein	UniProtKB/Swiss-Prot
	SSF110083	UniProtKB/Swiss-Prot
	SSF49503	UniProtKB/Swiss-Prot
TIGR	TC230849
UniProt	A0ABK0M357_RAT	UniProtKB/TrEMBL
	A6ITP8	ENTREZGENE, UniProtKB/TrEMBL
	A6ITP9_RAT	UniProtKB/TrEMBL
	F1LPA6_RAT	UniProtKB/TrEMBL
	P20717	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-14	Padi2	peptidyl arginine deiminase 2	Padi2	peptidyl arginine deiminase, type II	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Padi2	peptidyl arginine deiminase, type II	Pdi2	peptidyl arginine deiminase, type 2	Symbol and Name updated	1299863	APPROVED
2002-06-10	Pdi2	peptidyl arginine deiminase, type 2			Name updated	70585	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_product	member of a family of peptidylarginine deiminases	69925

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

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