Man2a1 (mannosidase, alpha, class 2A, member 1) - Rat Genome Database

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Gene: Man2a1 (mannosidase, alpha, class 2A, member 1) Rattus norvegicus
Analyze
Symbol: Man2a1
Name: mannosidase, alpha, class 2A, member 1
RGD ID: 3038
Description: Enables mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity and protein homodimerization activity. Involved in N-glycan processing. Located in Golgi membrane. Orthologous to human MAN2A1 (mannosidase alpha class 2A member 1); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha-mannosidase 2; alpha-mannosidase II; AMan II; golgi alpha-mannosidase II; MAN II; Mana2; MANNO; mannosidase 2, alpha 1; Mannosidase alpha 2; mannosidase alpha class 2A member 1; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89111,698,913 - 111,855,257 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9111,698,913 - 111,867,850 (+)EnsemblGRCr8
mRatBN7.29104,252,001 - 104,408,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9104,252,001 - 104,408,349 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9112,657,922 - 112,814,139 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09117,776,912 - 117,932,457 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09116,123,839 - 116,280,065 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09112,293,388 - 112,451,677 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9112,293,388 - 112,451,677 (+)Ensemblrn6Rnor6.0
Rnor_5.09111,831,033 - 111,987,870 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.49103,302,748 - 103,521,769 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9101,649,017 - 101,804,575 (+)NCBICelera
RGSC_v3.19103,532,052 - 103,581,682 (+)NCBI
Cytogenetic Map9q37NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
bafilomycin A1  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
corosolic acid  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
fenthion  (ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (EXP)
levonorgestrel  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
pirinixic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sevoflurane  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
swainsonine  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mannosidase II and the 135-kDa Golgi-specific antigen recognized monoclonal antibody 53FC3 are the same dimeric protein. Baron MD and Garoff H, J Biol Chem. 1990 Nov 15;265(32):19928-31.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Isolation of a rat liver Golgi mannosidase II clone by mixed oligonucleotide-primed amplification of cDNA. Moremen KW Proc Natl Acad Sci U S A 1989 Jul;86(14):5276-80.
6. Novel purification of the catalytic domain of Golgi alpha-mannosidase II. Characterization and comparison with the intact enzyme. Moremen KW, etal., J Biol Chem. 1991 Sep 5;266(25):16876-85.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11042173   PMID:15821732   PMID:16204232   PMID:16754854   PMID:19056867   PMID:19103603   PMID:19199708   PMID:19710420   PMID:19946888   PMID:20144606   PMID:21525244   PMID:22841714  
PMID:23000399   PMID:23376485   PMID:23533145   PMID:24741992   PMID:25797317  


Genomics

Comparative Map Data
Man2a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89111,698,913 - 111,855,257 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9111,698,913 - 111,867,850 (+)EnsemblGRCr8
mRatBN7.29104,252,001 - 104,408,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9104,252,001 - 104,408,349 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9112,657,922 - 112,814,139 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09117,776,912 - 117,932,457 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09116,123,839 - 116,280,065 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09112,293,388 - 112,451,677 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9112,293,388 - 112,451,677 (+)Ensemblrn6Rnor6.0
Rnor_5.09111,831,033 - 111,987,870 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.49103,302,748 - 103,521,769 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9101,649,017 - 101,804,575 (+)NCBICelera
RGSC_v3.19103,532,052 - 103,581,682 (+)NCBI
Cytogenetic Map9q37NCBI
MAN2A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385109,689,927 - 109,869,625 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5109,689,375 - 109,869,625 (+)Ensemblhg38GRCh38
GRCh375109,025,628 - 109,205,326 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365109,053,055 - 109,231,328 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345109,053,054 - 109,231,328NCBI
Celera5104,964,014 - 105,143,634 (+)NCBICelera
Cytogenetic Map5q21.3NCBI
HuRef5104,197,754 - 104,376,143 (+)NCBIHuRef
CHM1_15108,458,467 - 108,636,753 (+)NCBICHM1_1
T2T-CHM13v2.05110,194,449 - 110,374,084 (+)NCBIT2T-CHM13v2.0
Man2a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391764,907,683 - 65,062,105 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1764,907,731 - 65,062,105 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381764,600,688 - 64,755,110 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1764,600,736 - 64,755,110 (+)Ensemblmm10GRCm38
MGSCv371764,950,989 - 65,104,450 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361764,497,940 - 64,651,401 (+)NCBIMGSCv36mm8
Celera1768,918,943 - 69,071,751 (+)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1733.76NCBI
Man2a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554185,027,174 - 5,191,346 (-)Ensembl
ChiLan1.0NW_0049554185,027,962 - 5,191,346 (-)NCBIChiLan1.0ChiLan1.0
MAN2A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24104,934,923 - 105,119,871 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15103,089,640 - 103,273,527 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05105,034,104 - 105,219,011 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15110,841,349 - 111,025,187 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5110,841,349 - 111,025,187 (+)EnsemblpanPan2panpan1.1
MAN2A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.132,340,392 - 2,477,458 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl32,330,959 - 2,488,393 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha33,744,742 - 3,906,287 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.032,231,900 - 2,393,978 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl32,234,189 - 2,394,029 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.132,175,578 - 2,336,106 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.032,207,873 - 2,369,618 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.032,343,807 - 2,505,303 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Man2a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213157,117,374 - 157,280,182 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365314,331,200 - 4,494,131 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365314,331,354 - 4,494,110 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAN2A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2114,675,917 - 114,855,548 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12114,675,786 - 114,853,133 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22119,134,403 - 119,310,265 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAN2A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12313,094,383 - 13,268,286 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2313,094,538 - 13,268,283 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666036947,647 - 1,121,861 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Man2a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474327,607,094 - 27,791,612 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Man2a1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14174,656,845 - 174,820,418 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Man2a1
826 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:705
Count of miRNA genes:284
Interacting mature miRNAs:371
Transcripts:ENSRNOT00000020767
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat

Markers in Region
D9Got209  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29104,363,988 - 104,364,132 (+)MAPPERmRatBN7.2
Rnor_6.09112,407,259 - 112,407,402NCBIRnor6.0
Rnor_5.09111,943,452 - 111,943,595UniSTSRnor5.0
RGSC_v3.49103,477,405 - 103,477,548UniSTSRGSC3.4
Celera9101,760,291 - 101,760,434UniSTS
Cytogenetic Map9q37UniSTS
RH143712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29104,406,925 - 104,407,040 (+)MAPPERmRatBN7.2
Rnor_6.09112,450,254 - 112,450,368NCBIRnor6.0
Rnor_5.09111,986,447 - 111,986,561UniSTSRnor5.0
RGSC_v3.49103,520,346 - 103,520,460UniSTSRGSC3.4
Celera9101,803,152 - 101,803,266UniSTS
Cytogenetic Map9q37UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020767   ⟹   ENSRNOP00000020767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9111,698,913 - 111,855,257 (+)Ensembl
mRatBN7.2 Ensembl9104,252,001 - 104,408,349 (+)Ensembl
Rnor_6.0 Ensembl9112,293,388 - 112,451,677 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086682   ⟹   ENSRNOP00000070567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9111,698,913 - 111,867,850 (+)Ensembl
mRatBN7.2 Ensembl9104,252,001 - 104,368,923 (+)Ensembl
Rnor_6.0 Ensembl9112,360,419 - 112,412,112 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000160012   ⟹   ENSRNOP00000109663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9111,698,913 - 111,855,257 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000164647   ⟹   ENSRNOP00000105644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9111,698,913 - 111,855,257 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000170457   ⟹   ENSRNOP00000106253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9111,717,737 - 111,855,257 (+)Ensembl
RefSeq Acc Id: NM_012979   ⟹   NP_037111
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89111,698,913 - 111,855,257 (+)NCBI
mRatBN7.29104,252,001 - 104,408,349 (+)NCBI
Rnor_6.09112,293,388 - 112,451,677 (+)NCBI
Rnor_5.09111,831,033 - 111,987,870 (+)NCBI
RGSC_v3.49103,302,748 - 103,521,769 (+)RGD
Celera9101,649,017 - 101,804,575 (+)RGD
Sequence:
RefSeq Acc Id: XM_039083037   ⟹   XP_038938965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89111,723,165 - 111,855,253 (+)NCBI
mRatBN7.29104,276,256 - 104,408,345 (+)NCBI
Protein Sequences
Protein RefSeqs NP_037111 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938965 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA66457 (Get FASTA)   NCBI Sequence Viewer  
  AAP92563 (Get FASTA)   NCBI Sequence Viewer  
  EDL91825 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020767
  ENSRNOP00000020767.5
GenBank Protein P28494 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_037111   ⟸   NM_012979
- UniProtKB: G3V7Y9 (UniProtKB/Swiss-Prot),   P28494 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020767   ⟸   ENSRNOT00000020767
Ensembl Acc Id: ENSRNOP00000070567   ⟸   ENSRNOT00000086682
RefSeq Acc Id: XP_038938965   ⟸   XM_039083037
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000105644   ⟸   ENSRNOT00000164647
Ensembl Acc Id: ENSRNOP00000106253   ⟸   ENSRNOT00000170457
Ensembl Acc Id: ENSRNOP00000109663   ⟸   ENSRNOT00000160012
Protein Domains
Glycoside hydrolase family 38 central

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P28494-F1-model_v2 AlphaFold P28494 1-1148 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696901
Promoter ID:EPDNEW_R7425
Type:initiation region
Name:Man2a1_1
Description:mannosidase, alpha, class 2A, member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.09112,293,401 - 112,293,461EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3038 AgrOrtholog
BioCyc Gene G2FUF-26510 BioCyc
Ensembl Genes ENSRNOG00000015439 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020767 ENTREZGENE
  ENSRNOT00000020767.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1270.50 UniProtKB/Swiss-Prot
  2.60.40.1180 UniProtKB/Swiss-Prot
  3.20.110.10 UniProtKB/Swiss-Prot
  Golgi alpha-mannosidase II, domain 4 UniProtKB/Swiss-Prot
InterPro Gal_mutarotase_sf_dom UniProtKB/Swiss-Prot
  Glyco_hydro/deAcase_b/a-brl UniProtKB/Swiss-Prot
  Glyco_hydro_38_C UniProtKB/Swiss-Prot
  Glyco_hydro_38_cen UniProtKB/Swiss-Prot
  Glyco_hydro_38_cen_sf UniProtKB/Swiss-Prot
  Glyco_hydro_38_N UniProtKB/Swiss-Prot
  Glyco_hydro_38_N_sf UniProtKB/Swiss-Prot
  Glyco_hydro_57/38_cen_sf UniProtKB/Swiss-Prot
  Glyco_hydro_b UniProtKB/Swiss-Prot
  Glycosyl_Hydrlase_38 UniProtKB/Swiss-Prot
  Man2a1-like_dom UniProtKB/Swiss-Prot
KEGG Report rno:25478 UniProtKB/Swiss-Prot
NCBI Gene 25478 ENTREZGENE
PANTHER ALPHA-MANNOSIDASE UniProtKB/Swiss-Prot
  ALPHA-MANNOSIDASE 2 UniProtKB/Swiss-Prot
Pfam Alpha-mann_mid UniProtKB/Swiss-Prot
  Glyco_hydro_38C UniProtKB/Swiss-Prot
  Glyco_hydro_38N UniProtKB/Swiss-Prot
  Laman-like_dom UniProtKB/Swiss-Prot
PhenoGen Man2a1 PhenoGen
RatGTEx ENSRNOG00000015439 RatGTEx
SMART Alpha-mann_mid UniProtKB/Swiss-Prot
Superfamily-SCOP SSF74650 UniProtKB/Swiss-Prot
  SSF88688 UniProtKB/Swiss-Prot
  SSF88713 UniProtKB/Swiss-Prot
TIGR TC230437
UniProt A0A0G2JY93_RAT UniProtKB/TrEMBL
  A0ABK0L6J3_RAT UniProtKB/TrEMBL
  A0ABK0LU66_RAT UniProtKB/TrEMBL
  A0ABK0LWW1_RAT UniProtKB/TrEMBL
  G3V7Y9 ENTREZGENE
  MA2A1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q7TP82_RAT UniProtKB/TrEMBL
UniProt Secondary G3V7Y9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-06 Man2a1  mannosidase, alpha, class 2A, member 1  Man2a1  mannosidase 2, alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2000-11-11 Man2a1  Mannosidase 2, alpha 1      Symbol updated 61033 APPROVED
2000-11-11 Mana2  Mannosidase alpha 2      Symbol withdrawn 61033 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_protein 117 kDa 728956