Uhmk1 (U2AF homology motif kinase 1) - Rat Genome Database

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Pathways
Gene: Uhmk1 (U2AF homology motif kinase 1) Rattus norvegicus
Analyze
Symbol: Uhmk1 (Ensembl: Uhmk1l1)
Name: U2AF homology motif kinase 1 (Ensembl:U2AF homology motif kinase 1l1)
RGD ID: 2968
Description: Enables enzyme binding activity; protein serine/threonine kinase activity; and splicing factor binding activity. Involved in peptidyl-serine phosphorylation. Located in cytoplasm and nucleus. Orthologous to human UHMK1 (U2AF homology motif kinase 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kinase interacting stathmin; kinase interacting with leukemia-associated gene; kinase interacting with leukemia-associated gene (stathmin); kinase interacting with stathmin; Kis; Kist; MGC112620; P-CIP2; PAM COOH-terminal interactor protein 2; serine/threonine-protein kinase Kist; U2AF homology motif (UHM) kinase 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81384,929,418 - 84,949,194 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1384,922,829 - 84,949,061 (-)EnsemblGRCr8
mRatBN7.21382,396,646 - 82,416,292 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1382,401,187 - 82,416,292 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1385,028,615 - 85,043,704 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01386,321,792 - 86,336,896 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01383,553,853 - 83,568,942 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01388,521,625 - 88,536,728 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1388,521,625 - 88,536,728 (-)Ensemblrn6Rnor6.0
Rnor_5.01393,147,551 - 93,162,654 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41386,010,861 - 86,025,965 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1382,061,704 - 82,076,791 (-)NCBICelera
RGSC_v3.11386,025,048 - 86,040,153 (-)NCBI
Cytogenetic Map13q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (ISO)
cytoplasm  (IDA,IEA)
dendrite cytoplasm  (ISO)
neuronal ribonucleoprotein granule  (IBA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IDA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme. Alam MR, etal., J Biol Chem 1996 Nov 8;271(45):28636-40.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Different requirements of the kinase and UHM domains of KIS for its nuclear localization and binding to splicing factors. Manceau V, etal., J Mol Biol. 2008 Sep 5;381(3):748-62. doi: 10.1016/j.jmb.2008.06.026. Epub 2008 Jun 17.
5. KIS is a protein kinase with an RNA recognition motif. Maucuer A, etal., J Biol Chem 1997 Sep 12;272(37):23151-6.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10574929   PMID:12093740   PMID:12477932   PMID:19015237  


Genomics

Comparative Map Data
Uhmk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81384,929,418 - 84,949,194 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1384,922,829 - 84,949,061 (-)EnsemblGRCr8
mRatBN7.21382,396,646 - 82,416,292 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1382,401,187 - 82,416,292 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1385,028,615 - 85,043,704 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01386,321,792 - 86,336,896 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01383,553,853 - 83,568,942 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01388,521,625 - 88,536,728 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1388,521,625 - 88,536,728 (-)Ensemblrn6Rnor6.0
Rnor_5.01393,147,551 - 93,162,654 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41386,010,861 - 86,025,965 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1382,061,704 - 82,076,791 (-)NCBICelera
RGSC_v3.11386,025,048 - 86,040,153 (-)NCBI
Cytogenetic Map13q24NCBI
UHMK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,497,174 - 162,529,631 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,497,251 - 162,529,631 (+)Ensemblhg38GRCh38
GRCh371162,466,964 - 162,499,421 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,734,279 - 160,760,468 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341159,199,312 - 159,225,502NCBI
Celera1135,570,007 - 135,602,458 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1133,712,524 - 133,744,495 (+)NCBIHuRef
CHM1_11163,889,473 - 163,921,905 (+)NCBICHM1_1
T2T-CHM13v2.01161,841,193 - 161,873,634 (+)NCBIT2T-CHM13v2.0
Uhmk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,020,989 - 170,043,466 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,020,989 - 170,042,966 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381170,193,422 - 170,215,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,193,420 - 170,215,397 (-)Ensemblmm10GRCm38
MGSCv371172,129,387 - 172,145,524 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361171,476,645 - 171,492,776 (-)NCBIMGSCv36mm8
MGSCv361172,035,931 - 172,052,068 (-)NCBIMGSCv36mm8
Celera1172,635,566 - 172,695,028 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map176.84NCBI
Uhmk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546213,825,605 - 13,837,909 (-)Ensembl
ChiLan1.0NW_00495546213,819,107 - 13,837,679 (-)NCBIChiLan1.0ChiLan1.0
UHMK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2187,256,224 - 87,288,149 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1186,924,396 - 86,956,331 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01137,910,547 - 137,942,445 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11141,708,494 - 141,740,278 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1141,707,926 - 141,733,195 (+)EnsemblpanPan2panpan1.1
UHMK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13820,247,564 - 20,277,941 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3820,190,375 - 20,277,923 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3820,302,710 - 20,333,108 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03820,331,629 - 20,362,026 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3820,329,369 - 20,362,032 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13820,305,784 - 20,336,168 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03820,658,595 - 20,689,128 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03820,954,711 - 20,979,702 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Uhmk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050588,365,040 - 8,386,074 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936831680,867 - 695,328 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936831680,929 - 701,804 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UHMK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl488,029,339 - 88,052,937 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1488,029,332 - 88,052,935 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2495,987,526 - 95,990,936 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UHMK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1201,564,205 - 1,594,841 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl201,571,266 - 1,594,953 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038585,417 - 616,609 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uhmk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624826941,190 - 962,466 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624826941,200 - 966,470 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Uhmk1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11049,382,720 - 49,402,172 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Uhmk1
105 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:152
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000003950
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137161080489333251Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137161080489333251Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137161080489333251Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
AI171226  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21382,400,846 - 82,401,038 (+)MAPPERmRatBN7.2
Rnor_6.01388,521,285 - 88,521,476NCBIRnor6.0
Rnor_5.01393,147,211 - 93,147,402UniSTSRnor5.0
RGSC_v3.41386,010,521 - 86,010,712UniSTSRGSC3.4
Celera1382,061,364 - 82,061,555UniSTS
RH 3.4 Map13521.1UniSTS
Cytogenetic Map13q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003950   ⟹   ENSRNOP00000003950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1384,933,957 - 84,949,061 (-)Ensembl
mRatBN7.2 Ensembl1382,401,187 - 82,416,292 (-)Ensembl
Rnor_6.0 Ensembl1388,521,625 - 88,536,728 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108843   ⟹   ENSRNOP00000078491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1384,935,918 - 84,949,061 (-)Ensembl
mRatBN7.2 Ensembl1382,403,148 - 82,416,292 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114096   ⟹   ENSRNOP00000079145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1384,933,957 - 84,948,355 (-)Ensembl
mRatBN7.2 Ensembl1382,401,187 - 82,415,698 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000138868   ⟹   ENSRNOP00000098730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1384,922,829 - 84,949,061 (-)Ensembl
RefSeq Acc Id: NM_017293   ⟹   NP_058989
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81384,933,957 - 84,949,061 (-)NCBI
mRatBN7.21382,401,187 - 82,416,292 (-)NCBI
Rnor_6.01388,521,625 - 88,536,728 (-)NCBI
Rnor_5.01393,147,551 - 93,162,654 (-)NCBI
RGSC_v3.41386,010,861 - 86,025,965 (-)RGD
Celera1382,061,704 - 82,076,791 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090336   ⟹   XP_038946264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81384,929,418 - 84,949,194 (-)NCBI
mRatBN7.21382,396,646 - 82,415,617 (-)NCBI
RefSeq Acc Id: XM_063272023   ⟹   XP_063128093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81384,939,505 - 84,949,075 (-)NCBI
RefSeq Acc Id: XM_063272024   ⟹   XP_063128094
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81384,929,418 - 84,948,143 (-)NCBI
RefSeq Acc Id: NP_058989   ⟸   NM_017293
- UniProtKB: Q63285 (UniProtKB/Swiss-Prot),   A6IDP0 (UniProtKB/TrEMBL),   R9PXR8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003950   ⟸   ENSRNOT00000003950
RefSeq Acc Id: XP_038946264   ⟸   XM_039090336
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZM84 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079145   ⟸   ENSRNOT00000114096
Ensembl Acc Id: ENSRNOP00000078491   ⟸   ENSRNOT00000108843
RefSeq Acc Id: XP_063128094   ⟸   XM_063272024
- Peptide Label: isoform X3
- UniProtKB: A6IDN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128093   ⟸   XM_063272023
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZKY0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000098730   ⟸   ENSRNOT00000138868
Protein Domains
Protein kinase   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63285-F1-model_v2 AlphaFold Q63285 1-419 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698984
Promoter ID:EPDNEW_R9509
Type:multiple initiation site
Name:Uhmk1_1
Description:U2AF homology motif kinase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01388,536,734 - 88,536,794EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2968 AgrOrtholog
BioCyc Gene G2FUF-17483 BioCyc
Ensembl Genes ENSRNOG00000002941 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003950 ENTREZGENE
  ENSRNOT00000003950.5 UniProtKB/Swiss-Prot
  ENSRNOT00000108843 ENTREZGENE
  ENSRNOT00000114096 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
  Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
  UHMK1 UniProtKB/Swiss-Prot
  UHMK1_RRM UniProtKB/Swiss-Prot
KEGG Report rno:246332 UniProtKB/Swiss-Prot
NCBI Gene Uhmk1 ENTREZGENE
PANTHER PTHR46962 UniProtKB/Swiss-Prot
  SERINE/THREONINE-PROTEIN KINASE KIST UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
PhenoGen Uhmk1 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  RRM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002941 RatGTEx
SMART RRM UniProtKB/Swiss-Prot
  S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot
TIGR TC220657
UniProt A0A8I5ZKY0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZM84 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L8K6_RAT UniProtKB/TrEMBL
  A6IDN9 ENTREZGENE, UniProtKB/TrEMBL
  A6IDP0 ENTREZGENE, UniProtKB/TrEMBL
  Q4KMA6_RAT UniProtKB/TrEMBL
  Q63285 ENTREZGENE
  R9PXR8 ENTREZGENE, UniProtKB/TrEMBL
  UHMK1_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-24 Uhmk1  U2AF homology motif kinase 1  Uhmk1  U2AF homology motif (UHM) kinase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Uhmk1  U2AF homology motif (UHM) kinase 1  Kist  kinase interacting with leukemia-associated gene  Symbol and Name updated 1299863 APPROVED
2003-04-09 Kist  kinase interacting with leukemia-associated gene      Symbol and Name updated 629477 APPROVED
2003-03-12 Kist  kinase interacting with leukemia-associated gene  Kis  kinase interacting with leukemia-associated gene (stathmin)  Data merged from RGD:620564 628472 PROVISIONAL
2002-08-07 Kis  kinase interacting with leukemia-associated gene (stathmin)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Kist  kinase interacting with leukemia-associated gene      Name updated 70584 APPROVED
2002-01-14 Kist  kinase interacting with leukemia-associated gene (stathmin)      Correction to spelling of the symbol 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains an RNP-type RNA recognition motif 69873
gene_function phosphorylates stathmin, myelin basic protein and synapsin but not histones 69873