Gene: Uhmk1 (U2AF homology motif kinase 1) Rattus norvegicus
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Symbol:
Uhmk1 (Ensembl: Uhmk1l1)
Name:
U2AF homology motif kinase 1 (Ensembl:U2AF homology motif kinase 1l1)
RGD ID:
2968
Description:
Enables enzyme binding activity; protein serine/threonine kinase activity; and splicing factor binding activity. Involved in peptidyl-serine phosphorylation. Located in cytoplasm and nucleus. Orthologous to human UHMK1 (U2AF homology motif kinase 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
kinase interacting stathmin; kinase interacting with leukemia-associated gene; kinase interacting with leukemia-associated gene (stathmin); kinase interacting with stathmin; Kis; Kist; MGC112620; P-CIP2; PAM COOH-terminal interactor protein 2; serine/threonine-protein kinase Kist; U2AF homology motif (UHM) kinase 1
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 84,929,418 - 84,949,194 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 13 84,922,829 - 84,949,061 (-) Ensembl GRCr8 mRatBN7.2 13 82,396,646 - 82,416,292 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 82,401,187 - 82,416,292 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 13 85,028,615 - 85,043,704 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 13 86,321,792 - 86,336,896 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 13 83,553,853 - 83,568,942 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 13 88,521,625 - 88,536,728 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 88,521,625 - 88,536,728 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 13 93,147,551 - 93,162,654 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 13 86,010,861 - 86,025,965 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 13 82,061,704 - 82,076,791 (-) NCBI Celera RGSC_v3.1 13 86,025,048 - 86,040,153 (-) NCBI Cytogenetic Map 13 q24 NCBI
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Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Uhmk1 Rat (1->4)-beta-D-glucan multiple interactions ISO Uhmk1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UHMK1 mRNA CTD PMID:36331819 Uhmk1 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Uhmk1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uhmk1 Rat 1,2-dimethylhydrazine decreases expression ISO Uhmk1 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of UHMK1 mRNA CTD PMID:22206623 Uhmk1 Rat 17alpha-ethynylestradiol increases expression ISO Uhmk1 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of UHMK1 mRNA CTD PMID:12072388 Uhmk1 Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of UHMK1 mRNA CTD PMID:29097150 Uhmk1 Rat 17beta-estradiol decreases expression ISO UHMK1 (Homo sapiens) 6480464 Estradiol results in decreased expression of UHMK1 mRNA CTD PMID:21632981 Uhmk1 Rat 17beta-estradiol multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [Estradiol co-treated with Norethindrone Acetate] results in decreased expression of UHMK1 mRNA CTD PMID:22217510 Uhmk1 Rat 17beta-estradiol decreases expression ISO Uhmk1 (Mus musculus) 6480464 Estradiol results in decreased expression of UHMK1 mRNA CTD PMID:19484750 Uhmk1 Rat 17beta-estradiol increases expression ISO UHMK1 (Homo sapiens) 6480464 Estradiol results in increased expression of UHMK1 mRNA CTD PMID:23019147 Uhmk1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Uhmk1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uhmk1 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Uhmk1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uhmk1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of UHMK1 mRNA CTD PMID:22298810 Uhmk1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Uhmk1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of UHMK1 mRNA CTD PMID:21570461|PMID:24680724 Uhmk1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of UHMK1 mRNA CTD PMID:21215274|PMID:33387578 Uhmk1 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Uhmk1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uhmk1 Rat 4,4'-sulfonyldiphenol decreases expression ISO Uhmk1 (Mus musculus) 6480464 bisphenol S results in decreased expression of UHMK1 mRNA CTD PMID:39298647 Uhmk1 Rat 5-azacytidine increases expression ISO UHMK1 (Homo sapiens) 6480464 Azacitidine results in increased expression of UHMK1 mRNA CTD PMID:20823114 Uhmk1 Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of UHMK1 mRNA CTD PMID:31881176 Uhmk1 Rat acrolein multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... CTD PMID:32699268 Uhmk1 Rat aflatoxin M1 decreases expression ISO UHMK1 (Homo sapiens) 6480464 Aflatoxin M1 results in decreased expression of UHMK1 mRNA CTD PMID:30928695 Uhmk1 Rat alpha-pinene multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... CTD PMID:32699268 Uhmk1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of UHMK1 mRNA CTD PMID:16483693 Uhmk1 Rat arsenite(3-) multiple interactions ISO UHMK1 (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to UHMK1 mRNA] CTD PMID:32406909 Uhmk1 Rat arsenous acid increases expression ISO UHMK1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of KIS mRNA CTD PMID:20458559 Uhmk1 Rat benzo[a]pyrene increases expression ISO Uhmk1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of UHMK1 mRNA CTD PMID:20127859 Uhmk1 Rat benzo[a]pyrene affects methylation ISO UHMK1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of UHMK1 promoter CTD PMID:27901495 Uhmk1 Rat benzo[a]pyrene diol epoxide I decreases expression ISO UHMK1 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of UHMK1 mRNA CTD PMID:20018196 Uhmk1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of UHMK1 mRNA CTD PMID:26982218|PMID:29097150|PMID:33296240 Uhmk1 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of UHMK1 mRNA CTD PMID:25181051 Uhmk1 Rat bisphenol F increases expression ISO Uhmk1 (Mus musculus) 6480464 bisphenol F results in increased expression of UHMK1 mRNA CTD PMID:38685157 Uhmk1 Rat Butylbenzyl phthalate increases methylation ISO Uhmk1 (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of UHMK1 intron CTD PMID:28392331 Uhmk1 Rat cadmium atom multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of UHMK1 more ... CTD PMID:35301059 Uhmk1 Rat cadmium dichloride multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of UHMK1 more ... CTD PMID:35301059 Uhmk1 Rat cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of UHMK1 mRNA CTD PMID:18500788 Uhmk1 Rat chlorpyrifos decreases expression ISO Uhmk1 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of UHMK1 mRNA CTD PMID:37019170 Uhmk1 Rat coumestrol decreases expression ISO UHMK1 (Homo sapiens) 6480464 Coumestrol results in decreased expression of UHMK1 mRNA CTD PMID:19167446 Uhmk1 Rat CU-O LINKAGE increases expression ISO UHMK1 (Homo sapiens) 6480464 cupric oxide results in increased expression of UHMK1 mRNA CTD PMID:22077320 Uhmk1 Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of UHMK1 mRNA CTD PMID:27523638 Uhmk1 Rat cyclosporin A increases expression ISO UHMK1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of UHMK1 mRNA CTD PMID:25562108 Uhmk1 Rat diarsenic trioxide increases expression ISO UHMK1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of KIS mRNA CTD PMID:20458559 Uhmk1 Rat dorsomorphin multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Uhmk1 Rat ethanol affects splicing ISO Uhmk1 (Mus musculus) 6480464 Ethanol affects the splicing of UHMK1 mRNA CTD PMID:30319688 Uhmk1 Rat flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of UHMK1 mRNA CTD PMID:18035473 Uhmk1 Rat furan increases expression EXP 6480464 furan results in increased expression of UHMK1 mRNA CTD PMID:25539665 Uhmk1 Rat geldanamycin increases expression ISO UHMK1 (Homo sapiens) 6480464 geldanamycin results in increased expression of UHMK1 mRNA CTD PMID:26705709 Uhmk1 Rat iron dichloride increases expression ISO UHMK1 (Homo sapiens) 6480464 ferrous chloride results in increased expression of UHMK1 mRNA CTD PMID:35984750 Uhmk1 Rat kainic acid decreases expression ISO Uhmk1 (Mus musculus) 6480464 Kainic Acid results in decreased expression of UHMK1 mRNA CTD PMID:17997037 Uhmk1 Rat lead diacetate decreases expression ISO Uhmk1 (Mus musculus) 6480464 lead acetate results in decreased expression of UHMK1 mRNA CTD PMID:21829687 Uhmk1 Rat leflunomide decreases expression ISO UHMK1 (Homo sapiens) 6480464 leflunomide results in decreased expression of UHMK1 mRNA CTD PMID:28988120 Uhmk1 Rat mercury dichloride decreases expression ISO UHMK1 (Homo sapiens) 6480464 Mercuric Chloride results in decreased expression of UHMK1 mRNA CTD PMID:27188386 Uhmk1 Rat methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of UHMK1 mRNA CTD PMID:22584684 Uhmk1 Rat methylmercury chloride decreases expression ISO UHMK1 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of UHMK1 mRNA CTD PMID:28001369 Uhmk1 Rat nickel atom increases expression ISO UHMK1 (Homo sapiens) 6480464 Nickel results in increased expression of UHMK1 mRNA CTD PMID:24768652 Uhmk1 Rat ozone multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... CTD PMID:32699268 Uhmk1 Rat paracetamol increases expression ISO UHMK1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of UHMK1 mRNA CTD PMID:22230336 Uhmk1 Rat PCB138 multiple interactions ISO Uhmk1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uhmk1 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Uhmk1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UHMK1 mRNA CTD PMID:36331819 Uhmk1 Rat pirinixic acid multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Uhmk1 Rat quercetin increases expression ISO UHMK1 (Homo sapiens) 6480464 Quercetin results in increased expression of UHMK1 mRNA CTD PMID:21632981 Uhmk1 Rat resveratrol multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of UHMK1 mRNA CTD PMID:23557933 Uhmk1 Rat SB 431542 multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Uhmk1 Rat sodium arsenite increases expression ISO UHMK1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of UHMK1 mRNA CTD PMID:38568856 Uhmk1 Rat thimerosal decreases expression ISO UHMK1 (Homo sapiens) 6480464 Thimerosal results in decreased expression of UHMK1 mRNA CTD PMID:27188386 Uhmk1 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of UHMK1 mRNA CTD PMID:34492290 Uhmk1 Rat titanium dioxide increases methylation ISO Uhmk1 (Mus musculus) 6480464 titanium dioxide results in increased methylation of UHMK1 gene CTD PMID:35295148 Uhmk1 Rat trichostatin A decreases expression ISO UHMK1 (Homo sapiens) 6480464 trichostatin A results in decreased expression of UHMK1 mRNA CTD PMID:26272509 Uhmk1 Rat trichostatin A multiple interactions ISO UHMK1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Uhmk1 Rat triphenyl phosphate affects expression ISO UHMK1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of UHMK1 mRNA CTD PMID:37042841 Uhmk1 Rat triptonide increases expression ISO Uhmk1 (Mus musculus) 6480464 triptonide results in increased expression of UHMK1 mRNA CTD PMID:33045310 Uhmk1 Rat urethane increases expression ISO UHMK1 (Homo sapiens) 6480464 Urethane results in increased expression of UHMK1 mRNA CTD PMID:28818685 Uhmk1 Rat valproic acid decreases expression ISO UHMK1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of UHMK1 mRNA CTD PMID:27188386 Uhmk1 Rat vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of UHMK1 mRNA CTD PMID:23034163 Uhmk1 Rat vorinostat decreases expression ISO UHMK1 (Homo sapiens) 6480464 vorinostat results in decreased expression of UHMK1 mRNA CTD PMID:27188386