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Gene: Galr3 (galanin receptor 3) Rattus norvegicus

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Symbol:

Galr3

Name:

galanin receptor 3

RGD ID:

2658

Description:

Enables galanin receptor activity. Involved in neuropeptide signaling pathway. Predicted to be located in non-motile cilium. Predicted to be active in plasma membrane. Orthologous to human GALR3 (galanin receptor 3); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; ammonium chloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

GAL3-R; galanin receptor type 3; GALR-3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GALR3 (galanin receptor 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Galr3 (galanin receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Galr3 (galanin receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GALR3 (galanin receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GALR3 (galanin receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Galr3 (galanin receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GALR3 (galanin receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GALR3 (galanin receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Galr3 (galanin receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GALR2 (galanin receptor 2)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	GALR3 (galanin receptor 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Galr3 (galanin receptor 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	galr2b (galanin receptor 2b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)
Danio rerio (zebrafish):	galr2b (galanin receptor 2b)	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	AstA-R1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	AstA-R1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	npr-9	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	npr-9	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	galr3	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	galr3	Alliance	DIOPT (OrthoFinder\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	112,483,183 - 112,496,359 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	112,485,672 - 112,488,136 (+)	Ensembl				GRCr8
mRatBN7.2	7	110,603,525 - 110,608,429 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	110,605,226 - 110,607,685 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	112,354,734 - 112,357,195 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	114,578,265 - 114,580,725 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	114,546,898 - 114,549,359 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	120,271,451 - 120,276,243 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	120,273,117 - 120,275,581 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	120,264,117 - 120,267,226 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	117,014,148 - 117,017,058 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	106,939,441 - 106,941,991 (+)	NCBI		Celera
RGSC_v3.1	7	117,048,377 - 117,051,288 (+)	NCBI
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

major depressive disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

amphotericin B (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

clofibrate (ISO)

deoxynivalenol (EXP)

disodium selenite (ISO)

genistein (ISO)

lead(0) (ISO)

methylmercury chloride (ISO)

paracetamol (ISO)

quercitrin (ISO)

resveratrol (ISO)

testosterone (EXP)

titanium dioxide (ISO)

triptonide (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA)

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (IEA,ISO)

galanin-activated signaling pathway (IBA,IEA,ISO)

neuropeptide signaling pathway (IDA)

positive regulation of transcription by RNA polymerase II (IEA,ISO,ISS)

signal transduction (IEA)

Cellular Component

9+0 non-motile cilium (IEA,ISO)

cilium (IEA,ISO)

membrane (IEA)

non-motile cilium (IEA,ISO)

plasma membrane (IBA,IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

galanin receptor activity (IBA,IDA,IEA,ISO)

peptide hormone binding (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	A clonal rat pancreatic delta cell line (Rin14B) expresses a high number of galanin receptors negatively coupled to a pertussis-toxin-sensitive cAMP-production pathway.	Amiranoff B, etal., Eur J Biochem. 1991 Jan 30;195(2):459-63.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Restricted distribution of galanin receptor 3 (GalR3) mRNA in the adult rat central nervous system.	Mennicken F, etal., J Chem Neuroanat 2002 Nov;24(4):257-68.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels.	Smith KE, etal., J Biol Chem 1998 Sep 4;273(36):23321-6.
10.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
11.	Cloning and expressional characterization of a novel galanin receptor. Identification of different pharmacophores within galanin for the three galanin receptor subtypes.	Wang S, etal., J Biol Chem 1997 Dec 19;272(51):31949-52.

Additional References at PubMed

PMID:9832121	PMID:10619483	PMID:15944003	PMID:15944004	PMID:20974494	PMID:24316073	PMID:24517231	PMID:28154160

Genomics

Comparative Map Data

Galr3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	112,483,183 - 112,496,359 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	112,485,672 - 112,488,136 (+)	Ensembl				GRCr8
mRatBN7.2	7	110,603,525 - 110,608,429 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	110,605,226 - 110,607,685 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	112,354,734 - 112,357,195 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	114,578,265 - 114,580,725 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	114,546,898 - 114,549,359 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	120,271,451 - 120,276,243 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	120,273,117 - 120,275,581 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	120,264,117 - 120,267,226 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	117,014,148 - 117,017,058 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	106,939,441 - 106,941,991 (+)	NCBI		Celera
RGSC_v3.1	7	117,048,377 - 117,051,288 (+)	NCBI
Cytogenetic Map	7	q34	NCBI

GALR3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	37,823,382 - 37,825,485 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	37,822,198 - 37,825,485 (+)	Ensembl			hg38	GRCh38
GRCh37	22	38,219,389 - 38,221,492 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	36,549,335 - 36,551,448 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	22	36,543,888 - 36,546,002	NCBI
Celera	22	22,021,172 - 22,023,286 (+)	NCBI		Celera
Cytogenetic Map	22	q13.1	NCBI
HuRef	22	21,186,375 - 21,186,760 (+)	NCBI		HuRef
CHM1_1	22	38,178,127 - 38,180,240 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	38,285,004 - 38,287,108 (+)	NCBI		T2T-CHM13v2.0

Galr3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	78,926,085 - 78,927,758 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	78,926,085 - 78,927,758 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	79,041,885 - 79,043,558 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	79,041,885 - 79,043,558 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	78,872,315 - 78,873,988 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	78,869,187 - 78,870,728 (+)	NCBI		MGSCv36	mm8
Celera	15	81,143,514 - 81,145,186 (+)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	37.7	NCBI

Galr3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955413	24,195,817 - 24,198,010 (+)	NCBI	ChiLan1.0	ChiLan1.0

GALR3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	47,675,458 - 47,698,943 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	50,363,834 - 50,387,794 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	18,736,957 - 18,741,207 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	36,569,615 - 36,580,636 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

GALR3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	26,814,942 - 26,819,725 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	26,814,942 - 26,816,727 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	26,769,657 - 26,772,239 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	27,606,282 - 27,608,864 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	27,606,282 - 27,608,067 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	27,329,475 - 27,332,057 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	27,637,903 - 27,640,504 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	27,815,141 - 27,817,723 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Galr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	10,290,692 - 10,293,193 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936492	3,301,409 - 3,303,512 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GALR3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	10,023,746 - 10,026,120 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	10,024,332 - 10,027,171 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	7,423,818 - 7,426,604 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GALR3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	20,522,267 - 20,525,832 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	20,523,746 - 20,525,814 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	105,266,211 - 105,270,414 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Galr3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624752	10,089,811 - 10,091,726 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Galr3
60 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	70
Count of miRNA genes:	64
Interacting mature miRNAs:	65
Transcripts:	ENSRNOT00000014349
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	92388565	119280177	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	82111245	123048330	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	71621154	114982716	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	73618702	118618702	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	73557047	118557047	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	82111245	123048330	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	96700404	118618702	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
10450862	Kidm55	Kidney mass QTL 55	4.9		kidney mass (VT:0002707)	kidney weight (CMO:0000081)	7	72725037	117725037	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
10450856	Livw4	Liver weight QTL 4	3.8		liver mass (VT:0003402)	liver weight (CMO:0000092)	7	72725037	117725037	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	78682549	123682549	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	71621154	119349044	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

D7Wox47

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	110,605,830 - 110,605,979 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	120,273,722 - 120,273,876	NCBI	Rnor6.0
Rnor_5.0	7	120,264,722 - 120,264,876	UniSTS	Rnor5.0
RGSC_v3.4	7	117,014,753 - 117,014,907	UniSTS	RGSC3.4
Celera	7	106,940,046 - 106,940,199	UniSTS
Cytogenetic Map	7	q34	UniSTS

Expression

RNA-SEQ Expression

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Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	1	14	105	51	53	25	58	25	6	176	86	4	94	54	78	28	10	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594697	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC096473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF031522	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF073798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF079844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014349 ⟹ ENSRNOP00000014349

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	112,485,672 - 112,488,136 (+)	Ensembl
mRatBN7.2 Ensembl	7	110,605,226 - 110,607,685 (+)	Ensembl
Rnor_6.0 Ensembl	7	120,273,117 - 120,275,581 (+)	Ensembl

RefSeq Acc Id:

NM_019173 ⟹ NP_062046

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	112,485,672 - 112,488,136 (+)	NCBI
mRatBN7.2	7	110,605,226 - 110,607,685 (+)	NCBI
Rnor_6.0	7	120,273,117 - 120,275,581 (+)	NCBI
Rnor_5.0	7	120,264,117 - 120,267,226 (+)	NCBI
RGSC_v3.4	7	117,014,148 - 117,017,058 (+)	RGD
Celera	7	106,939,441 - 106,941,991 (+)	RGD

Sequence:

show sequence

GGCCCAGTACCTAGGACTGAGGAAGATGGCTGACATCCAGAACATTTCGCTGGACAGCCCAGGG
AGCGTAGGGGCTGTGGCAGTGCCTGTGATCTTTGCCCTCATCTTCCTGTTGGGCATGGTGGGCA
ATGGGCTGGTGTTGGCTGTGCTACTGCAGCCTGGCCCAAGTGCCTGGCAGGAGCCAAGCAGTAC
CACAGATCTCTTCATCCTCAACTTGGCCGTGGCCGACCTTTGCTTCATCCTGTGCTGCGTGCCC
TTCCAGGCAGCCATCTACACACTGGATGCCTGGCTCTTTGGGGCTTTCGTGTGCAAGACGGTAC
ATCTGCTCATCTACCTCACCATGTATGCCAGCAGCTTCACCCTGGCGGCCGTCTCCCTGGACAG
GTACCTGGCTGTGCGGCACCCACTGCGCTCCAGAGCCCTGCGCACCCCGCGCAACGCGCGCGCC
GCCGTGGGGCTCGTGTGGCTGCTGGCGGCTCTCTTTTCCGCGCCCTACCTAAGCTATTACGGCA
CGGTGCGCTACGGCGCGCTCGAGCTCTGCGTGCCCGCTTGGGAGGACGCGCGGCGGCGCGCGCT
GGACGTGGCCACCTTCGCCGCGGGCTACCTGCTGCCGGTGGCCGTGGTGAGCCTGGCCTACGGA
CGCACGCTATGTTTCCTATGGGCCGCCGTGGGTCCCGCGGGCGCGGCGGCAGCAGAGGCGCGCA
GACGGGCGACCGGCCGGGCGGGACGCGCCATGCTGGCAGTGGCCGCGCTCTACGCGCTTTGCTG
GGGCCCGCACCACGCGCTCATCCTCTGCTTCTGGTACGGCCGCTTCGCCTTCAGCCCGGCCACC
TACGCCTGTCGCCTGGCCTCGCACTGCCTCGCCTACGCCAACTCCTGCCTTAACCCGCTCGTCT
ACTCGCTCGCCTCGCGCCACTTCCGCGCGCGCTTCCGCCGCCTGTGGCCCTGCGGCCGTCGCCG
CCACCGCCACCACCACCGCGCTCATCGAGCCCTCCGTCGTGTCCAGCCGGCGTCTTCGGGCCCC
GCCGGTTATCCCGGCGACGCCAGGCCTCGTGGTTGGAGTATGGAGCCCAGAGGGGATGCTCTGC
GTGGTGGTGGAGAGACTAGACTAACCCTGTCCCCCAGGGGACCTCAATAACCCTGCCCGCTTGG
ACTCTGACGTC

hide sequence

RefSeq Acc Id:

XM_006241972 ⟹ XP_006242034

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	112,483,183 - 112,496,359 (+)	NCBI
mRatBN7.2	7	110,603,525 - 110,608,429 (+)	NCBI
Rnor_6.0	7	120,273,830 - 120,276,243 (+)	NCBI
Rnor_5.0	7	120,264,117 - 120,267,226 (+)	NCBI

Sequence:

show sequence

GTCACTGTGGCAGGTTCTTGCTCAAACGCTGACTTTGGTTTTGCTCTACCCTCTTCTATCCATC
ATGAACTTCTAGCCCAGATACCTGGTCAGATCCAGGCTGGAGGAACCAGGTCCCTGGGTCGAGT
GCCTGGAGACCTGGCCTCCTGTCTAAAGACCCATTTTTCTCTCCCTCCTCTGATAGGAAGATGG
CTGACATCCAGAACATTTCGCTGGACAGCCCAGGGAGCGTAGGGGCTGTGGCAGTGCCTGTGAT
CTTTGCCCTCATCTTCCTGTTGGGCATGGTGGGCAATGGGCTGGTGTTGGCTGTGCTACTGCAG
CCTGGCCCAAGTGCCTGGCAGGAGCCAAGCAGTACCACAGATCTCTTCATCCTCAACTTGGCCG
TGGCCGACCTTTGCTTCATCCTGTGCTGCGTGCCCTTCCAGGCAGCCATCTACACACTGGATGC
CTGGCTCTTTGGGGCTTTCGTGTGCAAGACGGTACATCTGCTCATCTACCTCACCATGTATGCC
AGCAGCTTCACCCTGGCGGCCGTCTCCCTGGACAGGTACCTGGCTGTGCGGCACCCACTGCGCT
CCAGAGCCCTGCGCACCCCGCGCAACGCGCGCGCCGCCGTGGGGCTCGTGTGGCTGCTGGCGGC
TCTCTTTTCCGCGCCCTACCTAAGCTACTACGGCACGGTGCGCTACGGCGCGCTCGAGCTCTGC
GTGCCCGCTTGGGAGGACGCGCGGCGGCGCGCGCTGGACGTGGCCACCTTCGCCGCGGGCTACC
TGCTGCCGGTGGCCGTGGTGAGCCTGGCCTACGGACGCACGCTATGTTTCCTATGGGCCGCCGT
GGGTCCCGCGGGCGCGGCGGCAGCAGAGGCGCGCAGACGGGCGACCGGCCGGGCGGGACGCGCC
ATGCTGGCAGTGGCCGCGCTCTACGCGCTTTGCTGGGGCCCGCACCACGCGCTCATCCTCTGCT
TCTGGTACGGCCGCTTCGCCTTCAGCCCGGCCACCTACGCCTGTCGCCTGGCCTCGCACTGCCT
CGCCTACGCCAACTCCTGCCTTAACCCGCTCGTCTACTCGCTCGCCTCGCGCCACTTCCGCGCG
CGCTTCCGCCGCCTGTGGCCCTGCGGCCGTCGCCGCCACCGCCACCACCACCGCGCTCATCGAG
CCCTCCGTCGTGTCCAGCCGGCGTCTTCGGGCCCCGCCGGTTATCCCGGCGACGCCAGGCCTCG
TGGTTGGAGTATGGAGCCCAGAGGGGATGCTCTGCGTGGTGGTGGAGAGACTAGACTAACCCTG
TCCCCCAGGGGACCTCAATAACCCTGCCCGCTTGGACTCTGACGTCTGTCAGAATGCCACCAAG
GAACATCTAGGGAACGGCAGTCTCGCCAGGCTCCACCAAAAAGCAGAGGCAAAGTTGCAGGGAC
ACATAGGTGATTAAAATTGGTCCACCCAACTAGACACGGTCCCAAAGCAGGCAGCCTCAGCCCT
ATCCAGAGCCAGTCTGGCAGGACAACAGCCCATTCGCCTGGCGGTACCTTCCAAGCCCAGTTTG
TTCTATCACCTCTGACTAGACCCTTTTGGTCCCAAGCTCTGAACTAACTTAAGTAATTCTGGGA
AGAAGCAGCGGAGACTAATAGTCCAGGCTGATCTAGAACTGGCTATTATAGCCAAGGACGACCT
TGAATTTCTGATCCTCCAGTTTATATGACCCAAGTGCTGGGATGATGAGTGCCCCAGACTCCTA
GCTGGTTCAAGCAGGGAATAACAAATATCCCTTTAGCTCTTACTGTGTACCTCGCAGAATGCTA
AGTTCCTTAGTAATCAAGGCGTTAAGGTAGATATGGTTAGCTTTCTTTTACACGCATAGAAATC
AAGGGTCAGAGCAGTCACCTTGGGAATGTTTGGTAGAGGCTGGATCTAAATCTATGACTGTCTA
ACAGATTTATGCTCCGTGGCTGGCCTTTTTTTGTACCTTGAAGTTTCTTTGGTTTCCATTGGTT
TATT

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Protein Sequences


Protein RefSeqs	NP_062046	(Get FASTA)	NCBI Sequence Viewer
	XP_006242034	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC26145	(Get FASTA)	NCBI Sequence Viewer
	AAC34590	(Get FASTA)	NCBI Sequence Viewer
	AAC35943	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014349
GenBank Protein	O88626	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_062046 ⟸ NM_019173

- UniProtKB:

Q9QWZ2 (UniProtKB/Swiss-Prot), O54914 (UniProtKB/Swiss-Prot), O88626 (UniProtKB/Swiss-Prot), A0A140TAA9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MADIQNISLDSPGSVGAVAVPVIFALIFLLGMVGNGLVLAVLLQPGPSAWQEPSSTTDLFILNL
AVADLCFILCCVPFQAAIYTLDAWLFGAFVCKTVHLLIYLTMYASSFTLAAVSLDRYLAVRHPL
RSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAG
YLLPVAVVSLAYGRTLCFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALIL
CFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYSLASRHFRARFRRLWPCGRRRHRHHHRAH
RALRRVQPASSGPAGYPGDARPRGWSMEPRGDALRGGGETRLTLSPRGPQ

hide sequence

RefSeq Acc Id:	XP_006242034 ⟸ XM_006241972
- Peptide Label:	isoform X1
- UniProtKB:	Q9QWZ2 (UniProtKB/Swiss-Prot), O54914 (UniProtKB/Swiss-Prot), O88626 (UniProtKB/Swiss-Prot), A0A140TAA9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADIQNISLDSPGSVGAVAVPVIFALIFLLGMVGNGLVLAVLLQPGPSAWQEPSSTTDLFILNL AVADLCFILCCVPFQAAIYTLDAWLFGAFVCKTVHLLIYLTMYASSFTLAAVSLDRYLAVRHPL RSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAG YLLPVAVVSLAYGRTLCFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALIL CFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYSLASRHFRARFRRLWPCGRRRHRHHHRAH RALRRVQPASSGPAGYPGDARPRGWSMEPRGDALRGGGETRLTLSPRGPQ hide sequence

Ensembl Acc Id:

ENSRNOP00000014349 ⟸ ENSRNOT00000014349

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O88626-F1-model_v2	AlphaFold	O88626	1-370	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2658	AgrOrtholog
BioCyc Gene	G2FUF-32785	BioCyc
Ensembl Genes	ENSRNOG00000027060	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000014349	ENTREZGENE
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot
InterPro	Galanin_rcpt	UniProtKB/Swiss-Prot
	Galnin_3_rcpt	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot
KEGG Report	rno:29235	UniProtKB/Swiss-Prot
NCBI Gene	29235	ENTREZGENE
PANTHER	GALANIN RECEPTOR 3	UniProtKB/Swiss-Prot
	LEUCOKININ RECEPTOR-RELATED	UniProtKB/Swiss-Prot
Pfam	7tm_1	UniProtKB/Swiss-Prot
PhenoGen	Galr3	PhenoGen
PRINTS	GALANIN3R	UniProtKB/Swiss-Prot
	GALANINR	UniProtKB/Swiss-Prot
	GPCRRHODOPSN	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000027060	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot
TIGR	TC224019
UniProt	A0A140TAA9	ENTREZGENE, UniProtKB/TrEMBL
	GALR3_RAT	UniProtKB/Swiss-Prot
	O54914	ENTREZGENE
	O88626	ENTREZGENE
	Q9QWZ2	ENTREZGENE
UniProt Secondary	O54914	UniProtKB/Swiss-Prot
	Q9QWZ2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Galr3	galanin receptor 3			Name updated	70584	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD