Nps (neuropeptide S) - Rat Genome Database

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Gene: Nps (neuropeptide S) Rattus norvegicus
Analyze
Symbol: Nps
Name: neuropeptide S
RGD ID: 2324597
Description: Involved in positive regulation of circadian sleep/wake cycle, wakefulness. Predicted to be located in extracellular region and synapse. Used to study morphine dependence. Orthologous to human NPS (neuropeptide S); INTERACTS WITH bisphenol A; dizocilpine maleate; 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100360071; Neuropeptide S-like
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81199,505,772 - 199,510,915 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1199,506,899 - 199,510,680 (+)EnsemblGRCr8
mRatBN7.21190,077,040 - 190,080,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1190,077,040 - 190,080,821 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1198,437,750 - 198,441,531 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01205,597,306 - 205,601,071 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01198,270,805 - 198,274,570 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01207,508,414 - 207,512,195 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,508,414 - 207,512,195 (+)Ensemblrn6Rnor6.0
Rnor_5.01214,442,729 - 214,446,510 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41194,887,958 - 194,892,866 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1187,793,965 - 187,797,746 (+)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
neuropeptide activity  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress. Ebner K, etal., Amino Acids. 2011 Oct;41(4):991-6. doi: 10.1007/s00726-011-1058-0. Epub 2011 Aug 23.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Morphine dependence is associated with changes in neuropeptide S receptor expression and function in rat brain. Ghazal P, etal., Peptides. 2013 Aug;46:6-12. doi: 10.1016/j.peptides.2013.05.001. Epub 2013 May 16.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Neuropeptide S receptor gene expression in alcohol withdrawal and protracted abstinence in postdependent rats. Ruggeri B, etal., Alcohol Clin Exp Res. 2010 Jan;34(1):90-7. doi: 10.1111/j.1530-0277.2009.01070.x. Epub 2009 Oct 23.
6. Neuropeptide S promotes wakefulness through activation of the posterior hypothalamic histaminergic and orexinergic neurons. Zhao P, etal., Neuroscience. 2012 Apr 5;207:218-26. doi: 10.1016/j.neuroscience.2012.01.022. Epub 2012 Jan 20.
Additional References at PubMed
PMID:15312648   PMID:15919054   PMID:17645946   PMID:18564106   PMID:19429110   PMID:20495497   PMID:20974945   PMID:21437203   PMID:21452235   PMID:25986404   PMID:26227793   PMID:26462664  
PMID:27224019   PMID:28433253   PMID:28805209   PMID:29118105   PMID:29157796   PMID:32044336   PMID:32441169   PMID:36195130   PMID:37832875  


Genomics

Comparative Map Data
Nps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81199,505,772 - 199,510,915 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1199,506,899 - 199,510,680 (+)EnsemblGRCr8
mRatBN7.21190,077,040 - 190,080,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1190,077,040 - 190,080,821 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1198,437,750 - 198,441,531 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01205,597,306 - 205,601,071 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01198,270,805 - 198,274,570 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01207,508,414 - 207,512,195 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,508,414 - 207,512,195 (+)Ensemblrn6Rnor6.0
Rnor_5.01214,442,729 - 214,446,510 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41194,887,958 - 194,892,866 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1187,793,965 - 187,797,746 (+)NCBICelera
Cytogenetic Map1q41NCBI
NPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810127,549,309 - 127,553,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10127,549,309 - 127,553,540 (+)Ensemblhg38GRCh38
GRCh3710129,347,573 - 129,351,804 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610129,237,603 - 129,240,925 (+)NCBIBuild 36Build 36hg18NCBI36
Celera10123,018,049 - 123,021,372 (+)NCBICelera
Cytogenetic Map10q26.2NCBI
HuRef10122,920,598 - 122,923,921 (+)NCBIHuRef
CHM1_110129,629,918 - 129,633,240 (+)NCBICHM1_1
T2T-CHM13v2.010128,444,335 - 128,448,567 (+)NCBIT2T-CHM13v2.0
Nps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397134,870,348 - 134,874,671 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7134,860,432 - 134,874,671 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm387135,268,619 - 135,272,942 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7135,258,703 - 135,272,942 (+)Ensemblmm10GRCm38
MGSCv377142,460,302 - 142,464,625 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv367142,436,414 - 142,464,444 (+)NCBIMGSCv36mm8
Celera7135,088,015 - 135,092,338 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map781.27NCBI
NPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28139,426,346 - 139,429,899 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110139,431,697 - 139,435,932 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010124,135,616 - 124,139,845 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110128,384,897 - 128,388,217 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10128,384,897 - 128,388,217 (+)EnsemblpanPan2panpan1.1
NPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12836,488,430 - 36,492,524 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2836,488,500 - 36,492,090 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2836,544,343 - 36,548,486 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02837,120,629 - 37,124,769 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2837,120,699 - 37,124,289 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12836,596,914 - 36,601,058 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02836,595,559 - 36,599,690 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02836,850,200 - 36,854,347 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721310,385,430 - 10,389,542 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648615,172,256 - 15,175,339 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648615,172,068 - 15,175,568 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14136,836,352 - 136,839,510 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.114136,835,630 - 136,839,511 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214148,566,054 - 148,569,278 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19120,168,749 - 120,176,288 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604881,554,586 - 81,558,810 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nps
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473719,447,495 - 19,451,005 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Nps
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1266,643,442 - 66,648,389 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nps
39 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:72
Count of miRNA genes:64
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000054896
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1177339686222339686Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1181059071226059071Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1181059071226059071Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1153679879205813246Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1182039247227039247Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1183564652228564652Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1160573753210707719Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1181059071226059071Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1160573753210707719Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1165278545210278545Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1161077990206077990Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1181059071226059071Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1168063662213063662Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1159894717207261263Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1163992710208992710Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1182535316227535316Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1181059071226059071Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1181059071226059071Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1181059071226059071Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1194786607207590403Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1162753891207753891Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1180739993225739993Rat
61378Bp43Blood pressure QTL 4322.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1191177449205813246Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1191190115223964326Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1172718770228180370Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1175967553200707874Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1178547286206690557Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1186298393231298393Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1185979875230979875Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1197807365233480676Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753210707719Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1165707719210707719Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1173363824227535316Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1132966869206393015Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1191260175236260175Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2325727Pia41Pristane induced arthritis QTL 41joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1188241285233241285Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1160573753210707719Rat
631670Iddm10Insulin dependent diabetes mellitus QTL 101.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1183564652205813246Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
endoderm
hemolymphoid system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
37 3 2 1 2 1 1 35 10 2

Sequence


Ensembl Acc Id: ENSRNOT00000054896   ⟹   ENSRNOP00000051780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1199,506,899 - 199,510,680 (+)Ensembl
mRatBN7.2 Ensembl1190,077,040 - 190,080,821 (+)Ensembl
Rnor_6.0 Ensembl1207,508,414 - 207,512,195 (+)Ensembl
RefSeq Acc Id: NM_001271113   ⟹   NP_001258042
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81199,506,899 - 199,510,680 (+)NCBI
mRatBN7.21190,077,040 - 190,080,821 (+)NCBI
Rnor_6.01207,508,414 - 207,512,195 (+)NCBI
Rnor_5.01214,442,729 - 214,446,510 (+)NCBI
Celera1187,793,965 - 187,797,746 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063281241   ⟹   XP_063137311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81199,505,772 - 199,510,915 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001258042 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137311 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000051780
  ENSRNOP00000051780.2
GenBank Protein P0C0P7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001258042   ⟸   NM_001271113
- Peptide Label: precursor
- UniProtKB: P0C0P7 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000051780   ⟸   ENSRNOT00000054896
RefSeq Acc Id: XP_063137311   ⟸   XM_063281241
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C0P7-F1-model_v2 AlphaFold P0C0P7 1-89 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2324597 AgrOrtholog
BioCyc Gene G2FUF-57161 BioCyc
Ensembl Genes ENSRNOG00000036653 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000054896 ENTREZGENE
  ENSRNOT00000054896.3 UniProtKB/Swiss-Prot
InterPro Neuropeptide_S UniProtKB/Swiss-Prot
KEGG Report rno:100360071 UniProtKB/Swiss-Prot
NCBI Gene 100360071 ENTREZGENE
PANTHER NEUROPEPTIDE S UniProtKB/Swiss-Prot
  PTHR36679 UniProtKB/Swiss-Prot
Pfam Neuropeptide_S UniProtKB/Swiss-Prot
PhenoGen Nps PhenoGen
RatGTEx ENSRNOG00000036653 RatGTEx
UniProt NPS_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-12-21 Nps  neuropeptide S  LOC100360071  Neuropeptide S-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100360071  Neuropeptide S-like      Symbol and Name status set to provisional 70820 PROVISIONAL