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Gene: Nt5c2 (5'-nucleotidase, cytosolic II) Rattus norvegicus

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Symbol:

Nt5c2

Name:

5'-nucleotidase, cytosolic II

RGD ID:

2323387

Description:

Enables 5'-nucleotidase activity. Involved in adenosine metabolic process and purine nucleoside monophosphate metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; cadmium dichloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cytosolic nucleoside phosphotransferase 5'N; cytosolic purine 5'-nucleotidase; LOC100363253; LOC294016

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NT5C2 (5'-nucleotidase, cytosolic II)	HGNC	Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nt5c2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nt5c2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NT5C2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NT5C2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nt5c2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NT5C2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NT5C2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nt5c2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Nt5c2 (5'-nucleotidase, cytosolic II)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	FN3K (fructosamine 3 kinase)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	NT5C2 (5'-nucleotidase, cytosolic II)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nt5c2 (5'-nucleotidase, cytosolic II)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nt5c2a (5'-nucleotidase, cytosolic IIa)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nt5c2b (5'-nucleotidase, cytosolic IIb)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nt5c2b (5'-nucleotidase, cytosolic IIb)	Alliance	DIOPT (OMA\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y71H10B.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG32549	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nt5c2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	255,712,797 - 255,838,285 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	255,713,909 - 255,838,403 (-)	Ensembl				GRCr8
mRatBN7.2	1	245,770,993 - 245,896,925 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	245,772,277 - 245,897,913 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	253,898,700 - 253,972,046 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	260,591,926 - 260,665,203 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	253,241,355 - 253,314,864 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	266,652,966 - 266,782,935 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	266,659,519 - 266,782,910 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	274,086,763 - 274,213,322 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	252,204,106 - 252,329,479 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	241,538,262 - 241,668,557 (-)	NCBI		Celera
RGSC_v3.1	1	252,468,096 - 252,541,637 (-)	NCBI
Cytogenetic Map	1	q54	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute lymphoblastic leukemia (ISO)

genetic disease (ISO)

hereditary spastic paraplegia (ISO)

hereditary spastic paraplegia 45 (ISO)

microcephaly (ISO)

Neurodevelopmental Disorders (ISO)

Recurrence (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dimethoxyphenol (ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

acrolein (ISO)

acrylamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amphotericin B (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (ISO)

bortezomib (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

cyclophosphamide (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

ferric oxide (ISO)

FR900359 (ISO)

gentamycin (EXP,ISO)

indometacin (EXP)

ivermectin (ISO)

ketamine (EXP)

lead(0) (ISO)

nitrates (ISO)

Nutlin-3 (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenosine metabolic process (IBA,IDA)

allantoin metabolic process (IEA,ISO)

dGMP catabolic process (IEA,ISO)

dGMP metabolic process (IDA,IEA,ISO)

GMP metabolic process (IDA,IEA,ISO)

IMP catabolic process (IEA,ISO)

IMP metabolic process (IBA,IDA,IEA,ISO)

negative regulation of defense response to virus by host (IEA,ISO)

nucleotide metabolic process (IEA)

protein K48-linked ubiquitination (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IEA,ISO,ISS)

Molecular Function

5'-nucleotidase activity (IBA,IDA,IEA,ISO)

ATP binding (IEA,ISO,ISS)

catalytic activity (IEA)

hydrolase activity (IEA)

identical protein binding (IEA,ISO,ISS)

metal ion binding (IEA)

nucleoside phosphotransferase activity (IEA,ISO,ISS)

nucleotide binding (IEA)

protein binding (ISO)

transferase activity (IEA)

ubiquitin protein ligase activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

adenine phoshoribosyltransferase deficiency pathway (ISO)

adenosine monophosphate deaminase deficiency pathway (ISO)

adenylosuccinate lyase deficiency pathway (ISO)

AICA-ribosuria pathway (ISO)

azathioprine pharmacodynamics pathway (ISO)

beta-ureidopropionase deficiency pathway (ISO)

dihydropyrimidinase deficiency pathway (ISO)

Kelley-Seegmiller syndrome pathway (ISO)

Lesch-Nyhan syndrome pathway (ISO)

mercaptopurine pharmacodynamics pathway (ISO)

mitochondrial neurogastrointestinal encephalopathy syndrome pathway (ISO)

molybdenum cofactor deficiency pathway (ISO)

niacin metabolic pathway (ISO)

orotic aciduria 1 pathway (ISO)

purine metabolic pathway (ISO)

purine nucleoside phosphorylase deficiency pathway (ISO)

pyrimidine metabolic pathway (ISO)

tioguanine pharmacodynamics pathway (ISO)

xanthinuria type I pathway (ISO)

xanthinuria pathway (ISO)

xanthinuria type II pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Purification and some properties of cytosol 5'-nucleotidase from rat liver.	Itoh R, Biochim Biophys Acta. 1981 Feb 13;657(2):402-10. doi: 10.1016/0005-2744(81)90326-0.
3.	Enzymes of adenosine metabolism in the brain: diurnal rhythm and the effect of sleep deprivation.	Mackiewicz M, etal., J Neurochem. 2003 Apr;85(2):348-57.
4.	Differences in cytosolic and mitochondrial 5'-nucleotidase and deoxynucleoside kinase activities in Sprague-Dawley rat and CD-1 mouse tissues: implication for the toxicity of nucleoside analogs in animal models.	Mirzaee S, etal., Toxicology. 2010 Jan 12;267(1-3):159-64. Epub 2009 Nov 12.
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:2848805	PMID:17405878

Genomics

Comparative Map Data

Nt5c2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	255,712,797 - 255,838,285 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	255,713,909 - 255,838,403 (-)	Ensembl				GRCr8
mRatBN7.2	1	245,770,993 - 245,896,925 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	245,772,277 - 245,897,913 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	253,898,700 - 253,972,046 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	260,591,926 - 260,665,203 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	253,241,355 - 253,314,864 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	266,652,966 - 266,782,935 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	266,659,519 - 266,782,910 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	274,086,763 - 274,213,322 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	252,204,106 - 252,329,479 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	241,538,262 - 241,668,557 (-)	NCBI		Celera
RGSC_v3.1	1	252,468,096 - 252,541,637 (-)	NCBI
Cytogenetic Map	1	q54	NCBI

NT5C2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	103,088,017 - 103,193,272 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	103,087,141 - 103,277,605 (-)	Ensembl			hg38	GRCh38
GRCh37	10	104,847,774 - 104,953,029 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	104,837,902 - 104,943,006 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	104,837,903 - 104,943,006	NCBI
Celera	10	98,586,161 - 98,693,349 (-)	NCBI		Celera
Cytogenetic Map	10	q24.32-q24.33	NCBI
HuRef	10	98,482,286 - 98,586,909 (-)	NCBI		HuRef
CHM1_1	10	105,130,653 - 105,236,813 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	103,974,258 - 104,079,521 (-)	NCBI		T2T-CHM13v2.0

Nt5c2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	46,873,829 - 47,003,613 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	46,871,756 - 47,003,592 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	19	46,885,390 - 47,015,174 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	46,883,317 - 47,015,153 (-)	Ensembl			mm10	GRCm38
MGSCv37	19	46,961,321 - 47,089,679 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	19	46,941,140 - 47,015,619 (-)	NCBI		MGSCv36	mm8
Celera	19	47,656,323 - 47,783,383 (-)	NCBI		Celera
Cytogenetic Map	19	C3	NCBI
cM Map	19	38.97	NCBI

Nt5c2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955485	7,317,588 - 7,394,448 (+)	Ensembl
ChiLan1.0	NW_004955485	7,318,006 - 7,394,448 (+)	NCBI	ChiLan1.0	ChiLan1.0

NT5C2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	114,973,901 - 115,164,301 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	114,979,344 - 115,169,729 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	99,687,366 - 99,790,744 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	103,148,578 - 103,251,513 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	103,148,578 - 103,251,513 (-)	Ensembl			panPan2	panpan1.1

NT5C2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	15,525,581 - 15,621,287 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	15,526,790 - 15,621,235 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	15,697,211 - 15,791,400 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	16,000,755 - 16,095,008 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	16,000,764 - 16,147,185 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	15,550,611 - 15,644,750 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	15,581,995 - 15,676,317 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	15,716,631 - 15,810,917 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nt5c2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	31,225,057 - 31,289,576 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936600	2,843,523 - 2,891,733 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936600	2,828,277 - 2,892,795 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NT5C2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	114,062,459 - 114,145,109 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	114,062,451 - 114,167,460 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	124,033,935 - 124,116,597 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NT5C2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	96,133,873 - 96,325,122 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	96,135,400 - 96,219,956 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	57,243,704 - 57,438,013 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nt5c2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624831	2,371,804 - 2,529,726 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624831	2,374,341 - 2,468,819 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nt5c2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	46,358,619 - 46,538,231 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nt5c2
867 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	127
Count of miRNA genes:	105
Interacting mature miRNAs:	113
Transcripts:	ENSRNOT00000027351
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	186658830	266453731	Rat
2293674	Bss39	Bone structure and strength QTL 39	7.1	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	1	210980612	255980612	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	226175591	270518180	Rat
1578775	Iddm21	Insulin dependent diabetes mellitus QTL 21	4.13		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	245782829	270518180	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	205233991	267096252	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	218829748	263829748	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	186658830	266453731	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
631837	Niddm35	Non-insulin dependent diabetes mellitus QTL 35		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	248619887	269633915	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
631836	Stl31	Serum triglyceride level QTL 31	4.64	5e-06	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	247133834	270518180	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
2293694	Bss38	Bone structure and strength QTL 38	7.05	0.0001	femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	1	210980612	255980612	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	237995023	269633915	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	233480549	270108840	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	200449456	256003563	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	234540191	270518180	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	233480549	270108840	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	207163993	269633915	Rat
2300175	Bmd40	Bone mineral density QTL 40	15.4	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	1	210980612	255980612	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	223134011	262090599	Rat
2293655	Bss36	Bone structure and strength QTL 36	10.66	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	210980612	255980612	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	225108840	270108840	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	228180370	266453608	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	208479811	269633915	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	224633915	269633915	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	232312773	270518180	Rat
2316896	Gluco57	Glucose level QTL 57	7.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	238398865	255849249	Rat
1358916	Kidm22	Kidney mass QTL 22	3.32		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	212738576	257738576	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	194786607	262083703	Rat
61400	Niddm1	Non-insulin dependent diabetes mellitus QTL 1	11		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	228180243	255849249	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
2293700	Bmd27	Bone mineral density QTL 27	6.6	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	210980612	255980612	Rat
2293701	Bmd34	Bone mineral density QTL 34	8.3	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	1	210980612	255980612	Rat
7387289	Uae45	Urinary albumin excretion QTL 45	2.86	0.0021	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	233204160	270518180	Rat
1581544	Rf52	Renal function QTL 52		0.05	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	241569529	269633915	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	210980612	255980612	Rat
631536	Lnnr2	Liver neoplastic nodule remodeling QTL 2	2.9	0.0005	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	1	243953669	270518180	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	185857683	270518180	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	226175591	270518180	Rat
631669	Iddm9	Insulin dependent diabetes mellitus QTL 9	2.8	0.039	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	233349180	270518180	Rat
7394701	Uae46	Urinary albumin excretion QTL 46	3.6	0.0056	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	210980612	255980612	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	228174566	270518180	Rat

Markers in Region

D1Got441

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	245,826,871 - 245,827,129 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	266,712,977 - 266,713,232	NCBI	Rnor6.0
Rnor_5.0	1	274,142,908 - 274,143,163	UniSTS	Rnor5.0
RGSC_v3.4	1	252,259,546 - 252,259,801	UniSTS	RGSC3.4
Celera	1	241,598,135 - 241,598,390	UniSTS
Cytogenetic Map	1		RGD

AU046797

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	245,817,403 - 245,817,646 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	266,703,514 - 266,703,756	NCBI	Rnor6.0
Rnor_5.0	1	274,133,445 - 274,133,687	UniSTS	Rnor5.0
RGSC_v3.4	1	252,250,083 - 252,250,325	UniSTS	RGSC3.4
Celera	1	241,588,793 - 241,589,035	UniSTS

RH138834

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	245,771,683 - 245,771,836 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	266,657,796 - 266,657,948	NCBI	Rnor6.0
Rnor_5.0	1	274,087,723 - 274,087,875	UniSTS	Rnor5.0
RGSC_v3.4	1	252,204,365 - 252,204,517	UniSTS	RGSC3.4
Celera	1	241,543,092 - 241,543,244	UniSTS
RH 3.4 Map	1	1627.7	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001401711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_002728891	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003753419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006223765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006223766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006223768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590386	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101431	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_215270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC097752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC105488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027351 ⟹ ENSRNOP00000027351

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	255,713,909 - 255,795,055 (-)	Ensembl
mRatBN7.2 Ensembl	1	245,772,277 - 245,853,693 (-)	Ensembl
Rnor_6.0 Ensembl	1	266,659,519 - 266,782,910 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103151 ⟹ ENSRNOP00000081125

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	255,713,909 - 255,761,340 (-)	Ensembl
mRatBN7.2 Ensembl	1	245,772,277 - 245,819,921 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103587 ⟹ ENSRNOP00000096997

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	255,713,909 - 255,838,403 (-)	Ensembl
mRatBN7.2 Ensembl	1	245,772,277 - 245,897,913 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109343 ⟹ ENSRNOP00000096604

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	245,772,277 - 245,845,892 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109706 ⟹ ENSRNOP00000080847

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	255,713,909 - 255,787,267 (-)	Ensembl
mRatBN7.2 Ensembl	1	245,772,540 - 245,845,934 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114230 ⟹ ENSRNOP00000084753

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	255,713,909 - 255,753,721 (-)	Ensembl
mRatBN7.2 Ensembl	1	245,772,277 - 245,812,337 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116166 ⟹ ENSRNOP00000088067

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	255,713,909 - 255,838,403 (-)	Ensembl
mRatBN7.2 Ensembl	1	245,772,277 - 245,897,913 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117913 ⟹ ENSRNOP00000097160

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	255,713,909 - 255,769,295 (-)	Ensembl
mRatBN7.2 Ensembl	1	245,772,277 - 245,828,185 (-)	Ensembl

RefSeq Acc Id:

NM_001401711 ⟹ NP_001388640

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	255,713,909 - 255,787,267 (-)	NCBI
mRatBN7.2	1	245,772,536 - 245,845,904 (-)	NCBI

RefSeq Acc Id:

XM_002728891 ⟹ XP_002728937

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	255,712,797 - 255,838,285 (-)	NCBI
mRatBN7.2	1	245,770,993 - 245,896,925 (-)	NCBI
Rnor_6.0	1	266,659,516 - 266,782,935 (-)	NCBI
Rnor_5.0	1	274,086,763 - 274,213,322 (-)	NCBI
RGSC_v3.4	1	252,204,106 - 252,329,479 (-)	RGD

Sequence:

show sequence

CAAGTAGTGCTCTGATCCGAAGCTCATGGTGCCGGGGTCGGGGCCGGGTGCGCGGCTGCGGCGG
GACCTGGCGAGGACGCGAAGAATTCATCCTACAAATAAAATGATGACTTCCTGGAGTGACCGCT
TACAGAACGCAGCAGATGTGCCTGCTAACATGGATAAGCATGCCCTGAAAAAGTACCGTCGAGA
AGCCTATCACCGGGTGTTTGTGAACCGAAGTTTAGCCATGGAAAAAATAAAGTGTTTTGGGTTT
GACATGGATTATACCCTGGCTGTGTACAAGTCTCCGGAATATGAATCCCTTGGCTTTGAGCTTA
CTGTGGAGAGATTAGTGTCCATCGGCTATCCTCAGGAGCTGCTCAACTTTGCATATGATTCGAC
ATTCCCTACCAGAGGACTTGTCTTTGACACACTCTATGGAAATCTCTTGAAAGTTGATGCCTAT
GGAAACCTCTTGGTTTGTGCACATGGATTTAACTTCATAAGAGGACCAGAAACTAGAGAGCAGT
ATCCAAATAAGTTTATCCAACGAGATGATACTGAACGGTTTTACATTCTGAACACACTCTTCAA
CCTTCCAGAAACCTACCTGTTGGCCTGCCTAGTAGATTTTTTTACTAATTGTCCCAGATATACC
AGTTGTGACACAGGATTTAAAGATGGGGACCTCTTCATGTCCTACAGGAGTATGTTCCAGGATG
TAAGGGACGCAGTGGACTGGGTCCATTACAAGGGTTCCCTTAAGGAAAAGACAGTTGAAAATCT
TGAGAAGTATGTAGTCAAAGATGGCAAGTTGCCGTTGCTTCTGAGCCGAATGAAGGAAGTGGGG
AAAGTGTTTCTGGCCACTAACAGTGACTATAAGTACACAGATAAAATCATGACTTACCTGTTTG
ATTTCCCACATGGCCCCAAGCCTGGGAGCTCCCACCGGCCGTGGCAGTCCTACTTTGATCTGAT
TTTGGTGGATGCACGGAAACCGCTCTTTTTTGGAGAAGGCACAGTGCTGCGTCAGGTGGACACT
AAAACCGGAAAACTGAAAATCGGCACCTACACGGGCCCCCTGCAGCATGGCATCGTCTACTCAG
GAGGTTCATCTGATACAATCTGTGACCTGTTGGGAGCTAAGGGCAAAGACATTTTGTATATTGG
AGATCACATTTTTGGAGACATTTTGAAGTCAAAGAAACGGCAAGGGTGGAGAACTTTCTTGGTG
ATTCCTGAGCTTGCACAAGAGCTGCACGTCTGGACTGACAAAAGTTCACTTTTTGAAGAACTTC
AAAGCTTGGATATTTTCTTGGCTGAACTCTACAAGCACCTGGACAGCAGCAGCAACGAGCGCCC
AGACATCAGTTCCATCCAGAGACGGATCAAGAAAGTGACTCATGACATGGACATGTGCTACGGG
ATGATGGGAAGCCTGTTCCGCAGTGGCTCCCGGCAGACGCTCTTTGCCAGCCAAGTGATGCGGT
ACGCTGACCTCTATGCAGCATCCTTCATCAACCTGCTGTACTACCCATTCAGCTACCTCTTCAG
AGCGGCCCACGTCCTGATGCCGCACGAATCAACAGTGGAGCACACACATGTGGATATCAATGAG
ATGGAGTCCCCTCTCGCCACCCGCAACCGCACATCGGTGGATTTCAAAGACACTGACTATAAGC
GACACCAGCTCACGAGGTCCATTAGTGAGATCAAGCCTCCCAACCTCTTCCCTCTGGCTCCCCA
GGAGATCACACACTGCCATGATGAAGATGATGATGAGGAAGAGGAAGAGGAAGAATAA

hide sequence

RefSeq Acc Id:

XM_039101429 ⟹ XP_038957357

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	255,712,797 - 255,777,139 (-)	NCBI
mRatBN7.2	1	245,770,993 - 245,835,763 (-)	NCBI

RefSeq Acc Id:

XM_039101430 ⟹ XP_038957358

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	255,712,797 - 255,787,386 (-)	NCBI
mRatBN7.2	1	245,770,993 - 245,846,149 (-)	NCBI

RefSeq Acc Id:

XM_039101431 ⟹ XP_038957359

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	255,712,797 - 255,774,938 (-)	NCBI
mRatBN7.2	1	245,770,993 - 245,833,578 (-)	NCBI

RefSeq Acc Id:

XM_039101432 ⟹ XP_038957360

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	255,712,797 - 255,724,736 (-)	NCBI
mRatBN7.2	1	245,770,993 - 245,783,380 (-)	NCBI

RefSeq Acc Id:

XM_063282768 ⟹ XP_063138838

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	255,712,797 - 255,788,798 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001388640	(Get FASTA)	NCBI Sequence Viewer
	XP_002728937	(Get FASTA)	NCBI Sequence Viewer
	XP_038957357	(Get FASTA)	NCBI Sequence Viewer
	XP_038957358	(Get FASTA)	NCBI Sequence Viewer
	XP_038957359	(Get FASTA)	NCBI Sequence Viewer
	XP_038957360	(Get FASTA)	NCBI Sequence Viewer
	XP_063138838	(Get FASTA)	NCBI Sequence Viewer
	XP_215270	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D3ZMY7	(Get FASTA)	NCBI Sequence Viewer
	EDL94365	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000080847
	ENSRNOP00000096997

RefSeq Acc Id:	XP_002728937 ⟸ XM_002728891
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6GLV2 (UniProtKB/TrEMBL), A0A8I6A978 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVPGSGPGARLRRDLARTRRIHPTNKMMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVN RSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLNFAYDSTFPTRGLVF DTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLA CLVDFFTNCPRYTSCDTGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDG KLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPL FFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDIL KSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRR IKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPH ESTVEHTHVDINEMESPLATRNRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLAPQEITHCHDE DDDEEEEEEE hide sequence

Ensembl Acc Id:

ENSRNOP00000027351 ⟸ ENSRNOT00000027351

RefSeq Acc Id:	XP_038957358 ⟸ XM_039101430
- Peptide Label:	isoform X1
- UniProtKB:	D3ZMY7 (UniProtKB/Swiss-Prot), A6JHP1 (UniProtKB/TrEMBL), A0A8L2QH70 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957357 ⟸ XM_039101429
- Peptide Label:	isoform X1
- UniProtKB:	D3ZMY7 (UniProtKB/Swiss-Prot), A6JHP1 (UniProtKB/TrEMBL), A0A8L2QH70 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038957359 ⟸ XM_039101431
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038957360 ⟸ XM_039101432
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000096997 ⟸ ENSRNOT00000103587

Ensembl Acc Id:

ENSRNOP00000088067 ⟸ ENSRNOT00000116166

Ensembl Acc Id:

ENSRNOP00000081125 ⟸ ENSRNOT00000103151

Ensembl Acc Id:

ENSRNOP00000084753 ⟸ ENSRNOT00000114230

Ensembl Acc Id:

ENSRNOP00000080847 ⟸ ENSRNOT00000109706

Ensembl Acc Id:

ENSRNOP00000096604 ⟸ ENSRNOT00000109343

Ensembl Acc Id:

ENSRNOP00000097160 ⟸ ENSRNOT00000117913

RefSeq Acc Id:	NP_001388640 ⟸ NM_001401711
- UniProtKB:	D3ZMY7 (UniProtKB/Swiss-Prot), A0A8L2QH70 (UniProtKB/TrEMBL), A6JHP1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138838 ⟸ XM_063282768
- Peptide Label:	isoform X1
- UniProtKB:	D3ZMY7 (UniProtKB/Swiss-Prot), A0A8L2QH70 (UniProtKB/TrEMBL), A6JHP1 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZMY7-F1-model_v2	AlphaFold	D3ZMY7	1-560	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2323387	AgrOrtholog
BioCyc Gene	G2FUF-55496	BioCyc
Ensembl Genes	ENSRNOG00000020179	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000103587	ENTREZGENE
	ENSRNOT00000109706	ENTREZGENE
Gene3D-CATH	3.40.50.1000	UniProtKB/Swiss-Prot
InterPro	HAD-like_sf	UniProtKB/Swiss-Prot
	HAD-SF_hydro_IG_5-nucl	UniProtKB/Swiss-Prot
	HAD_sf	UniProtKB/Swiss-Prot
	Pur_nucleotidase	UniProtKB/Swiss-Prot
NCBI Gene	100363253	ENTREZGENE
PANTHER	CYTOSOLIC PURINE 5'-NUCLEOTIDASE	UniProtKB/Swiss-Prot
	PTHR12103	UniProtKB/Swiss-Prot
Pfam	5_nucleotid	UniProtKB/Swiss-Prot
PhenoGen	Nt5c2	PhenoGen
PIRSF	Purine_5'-nucleotidase	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000020179	RatGTEx
Superfamily-SCOP	SSF56784	UniProtKB/Swiss-Prot
UniProt	5NTC_RAT	UniProtKB/Swiss-Prot
	A0A8I5ZQH0_RAT	UniProtKB/TrEMBL
	A0A8I5ZQZ0_RAT	UniProtKB/TrEMBL
	A0A8I6A1X9_RAT	UniProtKB/TrEMBL
	A0A8I6A978	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GLV2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GME6_RAT	UniProtKB/TrEMBL
	A0A8L2QH70	ENTREZGENE, UniProtKB/TrEMBL
	A6JHP1	ENTREZGENE, UniProtKB/TrEMBL
	D3ZMY7	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-09-11	Nt5c2	5'-nucleotidase, cytosolic II	LOC100363253	5'-nucleotidase, cytosolic II	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-06	LOC100363253	5'-nucleotidase, cytosolic II			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Nt5c2	5'-nucleotidase, cytosolic II	Nt5c2_predicted	5'-nucleotidase, cytosolic II (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Nt5c2_predicted	5'-nucleotidase, cytosolic II (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB