Rps10l1 (ribosomal protein S10-like 1) - Rat Genome Database

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Gene: Rps10l1 (ribosomal protein S10-like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps10l1
Name: ribosomal protein S10-like 1
RGD ID: 2323006
Description: Enables tRNA binding activity. A structural constituent of ribosome. Involved in ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 9. Orthologous to human RPS10 (ribosomal protein S10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; cadmium dichloride.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: 40S ribosomal protein S10; LOC100363439; ribosomal protein S10-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Rps10  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8677,766,103 - 77,766,657 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2672,030,876 - 72,031,430 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,030,876 - 72,031,440 (+)EnsemblmRatBN7.2
Rnor_6.0675,429,715 - 75,430,282 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,429,729 - 75,430,226 (+)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl1019,715,275 - 19,715,832 (-)Ensemblrn6Rnor6.0
Rnor_5.0684,968,909 - 84,969,476 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4674,838,974 - 74,839,471 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera670,881,022 - 70,881,589 (+)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. Milochau A, etal., FEBS Lett. 2014 Jun 27;588(14):2217-22. doi: 10.1016/j.febslet.2014.05.031. Epub 2014 May 29.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:925037   PMID:3378620   PMID:6873282   PMID:9915854  


Genomics

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:67
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000043250
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 22 86 164 114 120 82 38 82 320 146 148 70 82 38

Sequence


Ensembl Acc Id: ENSRNOT00000040278   ⟹   ENSRNOP00000046992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1019,715,275 - 19,715,832 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000043250   ⟹   ENSRNOP00000043693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl672,030,876 - 72,031,440 (+)Ensembl
Rnor_6.0 Ensembl675,429,729 - 75,430,226 (+)Ensembl
RefSeq Acc Id: XM_002729623   ⟹   XP_002729669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2672,030,872 - 72,031,441 (+)NCBI
Rnor_6.0675,429,715 - 75,430,282 (+)NCBI
Rnor_5.0684,968,909 - 84,969,476 (+)NCBI
RGSC_v3.4674,838,974 - 74,839,471 (+)RGD
Sequence:
Protein Sequences
GenBank Protein P63326 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_002729669   ⟸   XM_002729623
- Sequence:
Ensembl Acc Id: ENSRNOP00000043693   ⟸   ENSRNOT00000043250
Ensembl Acc Id: ENSRNOP00000046992   ⟸   ENSRNOT00000040278

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LT36-F1-model_v2 AlphaFold F1LT36 1-165 view protein structure
AF-P63326-F1-model_v2 AlphaFold P63326 1-165 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694595
Promoter ID:EPDNEW_R5119
Type:single initiation site
Name:Rps10l1_1
Description:ribosomal protein S10-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0675,429,719 - 75,429,779EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2323006 AgrOrtholog
BioCyc Gene G2FUF-37542 BioCyc
Ensembl Genes ENSRNOG00000030106 Ensembl
  ENSRNOG00000052141 Ensembl
  ENSRNOG00000066637 Ensembl
  ENSRNOG00000068503 ENTREZGENE
NCBI Gene 100363439 ENTREZGENE
PhenoGen Rps10l1 PhenoGen
RatGTEx ENSRNOG00000030106 RatGTEx
  ENSRNOG00000052141 RatGTEx
  ENSRNOG00000066637 RatGTEx
  ENSRNOG00000068503 RatGTEx
UniProt P63326 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-09-11 Rps10l1  ribosomal protein S10-like 1  LOC100363439  ribosomal protein S10-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100363439  ribosomal protein S10-like      Symbol and Name status set to provisional 70820 PROVISIONAL