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Gene: Dgkq (diacylglycerol kinase, theta) Rattus norvegicus

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Symbol:

Dgkq

Name:

diacylglycerol kinase, theta

RGD ID:

2320722

Description:

Enables ATP-dependent diacylglycerol kinase activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; regulation of gene expression; and regulation of steroid metabolic process. Located in nuclear matrix and nuclear speck. Orthologous to human DGKQ (diacylglycerol kinase theta); PARTICIPATES IN glycerolipid metabolic pathway; glycerophospholipid metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 17beta-estradiol; bisphenol A; paracetamol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

DAG kinase theta; DGKtheta; diacylglycerol kinase theta; LOC100361138

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DGKQ (diacylglycerol kinase theta)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Dgkq (diacylglycerol kinase, theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dgkq (diacylglycerol kinase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DGKQ (diacylglycerol kinase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DGKQ (diacylglycerol kinase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dgkq (diacylglycerol kinase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DGKQ (diacylglycerol kinase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DGKQ (diacylglycerol kinase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dgkq (diacylglycerol kinase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Dgkq (diacylglycerol kinase theta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CTSE (cathepsin E)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	DGKQ (diacylglycerol kinase theta)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dgkq (diacylglycerol kinase, theta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG31140	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dgk-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dgkq	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	1,203,380 - 1,217,536 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	1,203,565 - 1,218,024 (+)	Ensembl				GRCr8
mRatBN7.2	14	1,059,125 - 1,073,131 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	1,059,170 - 1,073,131 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	959,068 - 973,029 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	2,260,846 - 2,274,807 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	957,541 - 971,502 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	14	951,732 - 965,693 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	14	950,654 - 964,615 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	14	949,605 - 963,566 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	14	1,231,281 - 1,245,243 (+)	NCBI		F344_StmMcwi
Rnor_6.0	14	2,069,409 - 2,083,370 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	2,069,409 - 2,083,370 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	2,064,851 - 2,078,913 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	1,600,280 - 1,614,154 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	1,098,511 - 1,112,472 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Sjogren's syndrome (ISO)

Usher syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methylcholine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

chromium(6+) (ISO)

chrysene (ISO)

Dibutyl phosphate (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

epoxiconazole (ISO)

maneb (ISO)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (EXP)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

quercitrin (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

tetraphene (ISO)

trichostatin A (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vanadium atom (ISO)

vanadium(0) (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (ISO)

cellular response to bile acid (ISO)

diacylglycerol metabolic process (ISO,ISS)

epidermal growth factor receptor signaling pathway (ISO)

G protein-coupled receptor signaling pathway (ISO)

glycerolipid metabolic process (IBA,IEA,ISO)

intracellular signal transduction (IBA)

lipid metabolic process (IEA)

lipid phosphorylation (ISO,ISS)

negative regulation of gene expression (ISO)

phosphatidic acid biosynthetic process (ISO,ISS)

phospholipase C-activating G protein-coupled receptor signaling pathway (IEA,ISO)

positive regulation of gene expression (ISO)

positive regulation of protein kinase C signaling (ISO)

regulation of cholesterol metabolic process (ISO)

regulation of cortisol biosynthetic process (ISO)

regulation of gluconeogenesis (ISO)

regulation of progesterone biosynthetic process (ISO)

regulation of synaptic vesicle endocytosis (ISO)

regulation of TORC1 signaling (ISO)

regulation of transcription by RNA polymerase II (ISO)

response to cAMP (ISO)

signal transduction (IEA)

thrombin-activated receptor signaling pathway (ISO)

Cellular Component

cytoplasm (IEA,ISO)

cytoskeleton (IEA,ISO)

cytosol (IEA,ISO)

endosome (ISO)

glutamatergic synapse (ISO)

membrane (IBA)

nuclear matrix (IEA,IMP)

nuclear speck (IDA,IEA,ISO)

nucleolus (ISO)

nucleus (IEA,ISO)

plasma membrane (IEA,ISO)

postsynapse (ISO)

presynapse (ISO)

synapse (IEA)

vesicle membrane (ISO)

Molecular Function

alkylglycerol kinase activity (IEA)

ATP binding (IEA)

ATP-dependent diacylglycerol kinase activity (IBA,IEA,IMP,ISO,ISS)

diacylglycerol-dependent serine/threonine kinase activity (ISO)

DNA-binding transcription factor binding (ISO)

kinase activity (IEA)

kinase binding (ISO)

metal ion binding (IEA)

nucleotide binding (IEA)

phospholipase binding (ISO)

protein binding (ISO)

receptor tyrosine kinase binding (ISO)

transferase activity (IEA)

transmembrane receptor protein tyrosine kinase activator activity (ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

glycerolipid metabolic pathway (IEA)

glycerophospholipid metabolic pathway (IEA)

phosphatidylinositol 3-kinase signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Nuclear diacylglycerol kinase-theta is activated in response to nerve growth factor stimulation of PC12 cells.	Tabellini G, etal., Cell Signal. 2004 Nov;16(11):1263-71.

Additional References at PubMed

PMID:10066731	PMID:11309392	PMID:12799190	PMID:15632090	PMID:15632189	PMID:17664281	PMID:22627129	PMID:22732145	PMID:23091060	PMID:23610160	PMID:23767959	PMID:24369117
PMID:26748701

Genomics

Comparative Map Data

Dgkq
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	1,203,380 - 1,217,536 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	1,203,565 - 1,218,024 (+)	Ensembl				GRCr8
mRatBN7.2	14	1,059,125 - 1,073,131 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	1,059,170 - 1,073,131 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	959,068 - 973,029 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	2,260,846 - 2,274,807 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	957,541 - 971,502 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	14	951,732 - 965,693 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	14	950,654 - 964,615 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	14	949,605 - 963,566 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	14	1,231,281 - 1,245,243 (+)	NCBI		F344_StmMcwi
Rnor_6.0	14	2,069,409 - 2,083,370 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	2,069,409 - 2,083,370 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	2,064,851 - 2,078,913 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	1,600,280 - 1,614,154 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	1,098,511 - 1,112,472 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

DGKQ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	958,887 - 973,569 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	958,884 - 986,895 (-)	Ensembl			hg38	GRCh38
GRCh37	4	952,675 - 967,357 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	942,675 - 957,344 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	4	942,505 - 957,174	NCBI
Celera	4	889,584 - 904,387 (-)	NCBI		Celera
Cytogenetic Map	4	p16.3	NCBI
HuRef	4	924,040 - 936,230 (-)	NCBI		HuRef
CHM1_1	4	952,456 - 967,132 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	956,995 - 971,678 (-)	NCBI		T2T-CHM13v2.0

Dgkq
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	108,794,910 - 108,808,696 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	108,794,559 - 108,817,538 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	108,647,044 - 108,660,830 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	108,646,693 - 108,669,672 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	109,076,063 - 109,089,788 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	108,887,346 - 108,901,071 (-)	NCBI		MGSCv36	mm8
Celera	5	105,768,622 - 105,782,348 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	53.24	NCBI

Dgkq
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955514	453,886 - 464,978 (-)	Ensembl
ChiLan1.0	NW_004955514	452,548 - 475,240 (-)	NCBI	ChiLan1.0	ChiLan1.0

DGKQ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	1,288,097 - 1,303,103 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	1,255,455 - 1,270,606 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	1,075,133 - 1,090,081 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	993,261 - 1,009,414 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	994,985 - 1,007,724 (-)	Ensembl			panPan2	panpan1.1

DGKQ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	91,544,350 - 91,554,494 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	91,544,219 - 91,554,565 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	94,009,425 - 94,019,552 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	92,541,158 - 92,551,573 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	92,540,425 - 92,551,567 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	91,714,767 - 91,724,838 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	91,767,739 - 91,777,865 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	92,151,558 - 92,161,686 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dgkq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	68,523,999 - 68,537,133 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936477	22,225,618 - 22,238,803 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936477	22,225,624 - 22,238,825 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DGKQ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	313,329 - 325,095 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	8	313,325 - 325,089 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

DGKQ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	47,804,904 - 47,819,291 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	47,805,017 - 47,817,583 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666808	9,565 - 24,022 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dgkq
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624755	26,179,162 - 26,189,901 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624755	26,179,099 - 26,197,764 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Dgkq
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	18,434,365 - 18,448,304 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Dgkq
46 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	469
Count of miRNA genes:	247
Interacting mature miRNAs:	296
Transcripts:	ENSRNOT00000032056
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411573	Bw139	Body weight QTL 139	4.7	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	14	1	40068101	Rat
9589814	Gluco67	Glucose level QTL 67	4.54	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	40068101	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41415516	Rat
71115	Niddm15	Non-insulin dependent diabetes mellitus QTL 15	4.8		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	11334906	Rat
71117	Niddm17	Non-insulin dependent diabetes mellitus QTL 17	2.35		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1	17877928	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1	31893212	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001198804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091545	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091546	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC117047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000032056 ⟹ ENSRNOP00000036466

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	1,203,565 - 1,217,535 (+)	Ensembl
mRatBN7.2 Ensembl	14	1,059,170 - 1,073,131 (+)	Ensembl
Rnor_6.0 Ensembl	14	2,069,409 - 2,083,370 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000155561 ⟹ ENSRNOP00000108077

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	1,203,565 - 1,218,024 (+)	Ensembl

RefSeq Acc Id:

NM_001198804 ⟹ NP_001185733

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,575 - 1,217,536 (+)	NCBI
mRatBN7.2	14	1,059,170 - 1,073,131 (+)	NCBI
Dahl_SR_JrHsd	14	951,732 - 965,693 (+)	NCBI
Lyon_Normotensive	14	950,654 - 964,615 (+)	NCBI
Lyon_Hypertensive	14	949,605 - 963,566 (+)	NCBI
F344_StmMcwi	14	1,231,281 - 1,245,243 (+)	NCBI
Rnor_6.0	14	2,069,409 - 2,083,370 (+)	NCBI
Rnor_5.0	14	2,064,851 - 2,078,913 (+)	NCBI
Celera	14	1,098,511 - 1,112,472 (+)	NCBI

Sequence:

show sequence

GCCGGGAGCAGGCACAGCCTAAGGCCCTCGTTACACCGCGGACCTGGCTTTAGCGTGCACCTGG
AGTTGGGGCGCTCGGGTTGTGAGATGGCGACGGCAGCCGAGTCCGGGGCCCGGACCTGGCCGGG
CAGTGGTTCCCCACGTCTCGGCAGCCCGGCCGGCAGCCCTGTGCTGGGCATCTCGGGCCGCGCA
CGCCCGGGGTCAGGGCCGGAGCGGACTGGCAGAGCTATCGGCTCCGTAGCACCCGGCCACAGCT
TTCGCAAGGTGACACTCACCAAGCCTACCTTCTGCCACCTCTGCTCGGACTTCATCTGGGGATT
GGCCGGCTTCCTGTGCGATGTCTGCAACTTCATGTCCCATGAGAAGTGCCTAAAGCAGGTGAAG
ACCCCGTGCACAAGCATTGCGCCAAGCCTCGTCCGGGTCCCTGTAGCCCACTGCTTTGGTTCCC
TTGGTCTCTACAAGCGCAAGTTCTGTGTGGTCTGCCGCAAGAGCCTGGAGGTACCTGCGTTCCG
CTGTGAAGTGTGTGAGCTGCACGTTCACCCCGACTGTGTGCCCTTCGCCTGCAGCGACTGTCGT
CAGTGTCACCAGGATGGACAGCACGATTATGACACGTATCACCACCACTGGAGGGAGGGGAATC
TGCCTTCTGGTGCTCGATGTGAGGTCTGTAGGAAGACTTGTGGCTCCTCGGATGTGCTGGCTGG
TGTACGCTGCGAGTGGTGTGGTGTACAGGCTCACTCCGTGTGCTCCACAGCACTCACCCCTGAG
TGTACATTTGGACGTCTACGCTCCATGGTACTGCCTCCTTCGTGTGTGCGCCTGTTGTCCCGAA
ACTTCAGCAAGATGCACTGCTTCCGAATCCCCGAGACCATGGTCCTGGAGCTCGGTGATGGGGA
TGATGGCCTAGATGGGAGTGCTGCAGTCGGCACAGGCAGAGAGGTATCGGCAGCTACAGAATCT
ACCAAACAGACCCTGAAGATCTTTGATGGCAACGACTCCATGAGGAAAAATCAGTTTCGCCTGG
TTACAGTTTCCCGCCTAGCTCGGAATGAGGAAGTGATGGAGGCAGCACTCCGGGCCTACTATAT
CAACGAGGACCCTAAGGACTTCCAGCTGCAGGCACTGCCCCTAACGTTACTGTCTGGCAATGCC
CAGGCTCTGGGGAAGGCCGGGACCACTGAGGAGGAGACAAGTAAAGACTCCGGGCCCGGGGATT
CCGTGCCTGAGGCCTGGGTCATCAGGTCTCTGCCTCGTACCCAAGAGATCCTGAAGATCTACCC
TGACTGGCTCAAGGTAGGTGTGGCCTACGTGTCCATCCGTGTGAACTCCCAGAGTACAGCACGG
TCTGTGGTTCAAGAGGTTCTCCCACTGTTTGGACGACAGGTTGAGGATCAGGAGAGATTCCAGC
TGATTGAGGTGCTTATGAGCAGCAGACAAGTCCAACGGACGGTGCTGGTGGATGAAGAACCTCT
GCTAGATCGACTCCGGGACATCCGACAGACATCTGTGCGCCAGGCGAGCCAGACGCGGTTCTAT
GTGGCCGAGGCCAGGGCCGTGACCCCACATGTCTCCCTGTTTGTGGGTGGCCTGCCACCTGGCT
TGTCCCCTCAGGATTACAGCAACCTGCTGCATGAGGCCATGGCCACCAAAGCTGCTGTGGTGTC
TGTGAGTCACGTCTACTCCTTACAAGGTGCGGTAGTTCTGGATGTCACCTGCTTCGCGGAGGCT
GAGCGGCTATACATGCTGGCCAGGGACACAGCAGTGCATGGCCGGCCACTGACTGCACTAGTGC
TTCCAGATGTGCTGCACACGAAGCTGCCTCCTGACTGCTGCCCTCTCCTCGTGTTTGTGAACCC
CAAGAGTGGGGGCCTCAAGGGACGAGAACTGCTCTGCAGTTTCCGGAAGCTGCTGAATCCACAC
CAGGTCTTTGAGCTCACCAACGGGGGCCCTCTTCCTGGGTTCCACCTTTTCTCCCAGGTGCCCT
GCTTTCGGGTACTGGTCTGTGGTGGAGATGGCACCGTGGGCTGGGTGCTCGCTGCCCTGGAGGA
GACAAGGCGCCATCTGGCCTGCCCAGAGCCATCTGTGGCCATCCTACCCCTGGGTACAGGGAAT
GACCTTGGCCGGGTCCTCCGTTGGGGAGCAGGCTATAGTGGTGAGGACCCATTTTCTGTGCTGG
TGTCTGTGGATGAGGCTGATGCTGTGCTCATGGATCGATGGACAATCCTGCTGGACGCTCATGA
AATTGATAGTACAGAGAACAATGTGGTAGAAACAGAGCCCCCCAAGATTGTTCAGATGAATAAC
TACTGTGGCATTGGCATTGATGCGGAGCTCAGCCTAGACTTCCACCAGGCACGTGAAGAGGAGC
CTGGCAAATTCACAAGCAGGTTCCACAACAAGGGCGTGTATGTGCGGGTTGGGCTGCAGAAGAT
CAGCCACTCTCGAAGCCTGCACAAGGAGATCCGTCTGCAGGTGGAGCAGCAGGAAGTGGAGCTG
CCCAGCATTGAGGGTCTTATCTTCATTAACATCCCCAGCTGGGGCTCAGGGGCTGACCTGTGGG
GCTCTGACAGTGACTCAAGGTTTGAGAAGCCACGCATAGACGACGGGCTGTTGGAGGTGGTGGG
TGTGACAGGTGTCGTGCACATGGGCCAGGTACAAGGTGGGCTGCGCTCTGGAATCCGAATCGCC
CAGGGCTCCTACTTCCGTGTCACACTCCTCAAGGCTACTCCAGTGCAGGTGGACGGTGAGCCCT
GGATTCAGGCCCCAGGTCACATGATCATCTCTGCTACTGCACCTAAGGTTCACATGCTGAGGAA
AGCTAAGCAGAAGCCCAGGAAGGCTGGCGCCATCAGGGATACCCGAGTGGACACCTTGCCTGCT
CCTGAGGGCAATCCTTTATAGAGGAGCCAAGATGAAAGGTCTCAGCCACCCAGCCTTTCTCATC
TTTGGTTGGTCACACGCTGGCTGGCCAACAGATGGACTTAGCTGTAGCACTGACCATAGAATCT
CCATGGGTCTTGGGATGTTTCGATCCCTCATCCTTATCCAGTATCACGTGCAAACTTAGGAGAG
GGTAGGTAATGGTCACTACTCACTCCGCCTTAGTACCAAGGTATTGACTGGGCACAAGGCTCTG
GAAAGCTTGTATTCTGCACAAGACTGATTCTCACAGGATGAGCGAAGCTGGTCCTTCCTGTTAG
CCACATTCCTTCCCTCCTTTGAAACCTCTCTTAAGAACTCTCTTGGACCTAATACATCTGGATG
CAGGCCATCCAGGTGGGTCCTCTGATTTCACTTTATGTTCTTTCAAAACAGCTAACCATGTTGG
GCCCTGGCCTCCATGCTGCCTGTTCTCCTGTACTGATTAGATGGATGTGGCATCCTCAAGTCCC
CTGGGCTTATCACTAGACAGCAATTTGGGCTGAAGATAGTTACAAGGTCTCATCCAGCTGGCAG
CCATGAACTGACCAAGTTGTACTTAGGGATGGGAATCTTTGTCTACCCTGAGGGTAGGTGAGTT
TAGCTATCACGCATGTGTCACACACAGCTGGAGTGTGTGCTAGGCCGTGTGTCCCTCCTTGACC
ACTGAGTGGGCACCTAGTGCCCAGAAAGGATCAGAACAGGCCGGGTGGTACCTGGCTGAGGAGT
GTGTAAATAACTCCTGCTGTGGAGCAGCTAGAACTCCCTTAGACTCGACTTACAGCACTTTATA
GACATGGTATTTGCCTGCCTACAGCCCTTCCTTGTAGATGTAGAGCTTCTACTCTGGCTCCTAA
ACAAATGGAAGCAGCTCTGATGGCCAGGCCTTGCTGGAGACACTGGGTTCACAGAATGAGACAA
ATGCTGTCTCTTCCATGCACCCAAGAATTCATTGTCACACCTCAGACCCTAGGAAGAATCTGCC
CAGAAATGAGCTGTCTAGGTAAGCCTGGTACATGCCAATAATGGGCTAAAGCATAACTGTGTCA
TAGAGCTAAATAAAGCCCCTGTCAGAAAGTGAACACGTTAAAGACATTGAAAGCTCTAGCCTCA
GCCCTGGATAGGGGGAGACTCACATGGAAAGTCTCCTGTGATGCTTACCTCCCACCCCCAAAAG
TATGTCTAGAGCCTTTTCCAGTTTGTCATTACTCAGCTTGTGGACACCTTCAGAAGTGTGACAC
TGGGGTGGTGTGGACCAGGGTGTCTACCTGCCTGGCAGCTTCATAGGACCATTGTGCCACCCGC
TCACCTGCTTCTGCCAAAACTGCATACAAGTACATCAGATAGCCATTTGTGATCTCAGTGTGGA
TGATCATGTTTACACCATTTTCAATGTTCAAAAGAAATTCGTTGTGATGTAGTTTTTCCTTTTT
ATTTCAATCTGTAGAACTGTGTGTAAATTATGGTCAGTGTAGCATGTCCTCTGTATTTAAGTGA
GACTGTCCTCTTGTGGAGTGTGTCCTGTCTACTGGTCCTGTCTTTGTCTGTAAATTTATCACTA
CCTGAATGTGATCTAATTTATATCTGGGCCAAATATAGTGTGGGCTTTGCTGTCCC

hide sequence

RefSeq Acc Id:

XM_039091544 ⟹ XP_038947472

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,401 - 1,217,535 (+)	NCBI
mRatBN7.2	14	1,059,127 - 1,073,130 (+)	NCBI

RefSeq Acc Id:

XM_039091545 ⟹ XP_038947473

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,395 - 1,217,535 (+)	NCBI
mRatBN7.2	14	1,059,126 - 1,073,130 (+)	NCBI

RefSeq Acc Id:

XM_039091546 ⟹ XP_038947474

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,399 - 1,217,535 (+)	NCBI
mRatBN7.2	14	1,059,126 - 1,073,130 (+)	NCBI

RefSeq Acc Id:

XM_039091547 ⟹ XP_038947475

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,406 - 1,217,535 (+)	NCBI
mRatBN7.2	14	1,059,127 - 1,073,130 (+)	NCBI

RefSeq Acc Id:

XM_039091549 ⟹ XP_038947477

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,408 - 1,217,535 (+)	NCBI
mRatBN7.2	14	1,059,127 - 1,073,130 (+)	NCBI

RefSeq Acc Id:

XM_039091551 ⟹ XP_038947479

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,391 - 1,212,595 (+)	NCBI
mRatBN7.2	14	1,059,126 - 1,068,274 (+)	NCBI

RefSeq Acc Id:

XM_039091552 ⟹ XP_038947480

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,391 - 1,213,835 (+)	NCBI
mRatBN7.2	14	1,059,126 - 1,069,420 (+)	NCBI

RefSeq Acc Id:

XM_063272789 ⟹ XP_063128859

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,203,380 - 1,214,421 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001185733	(Get FASTA)	NCBI Sequence Viewer
	XP_038947472	(Get FASTA)	NCBI Sequence Viewer
	XP_038947473	(Get FASTA)	NCBI Sequence Viewer
	XP_038947474	(Get FASTA)	NCBI Sequence Viewer
	XP_038947475	(Get FASTA)	NCBI Sequence Viewer
	XP_038947477	(Get FASTA)	NCBI Sequence Viewer
	XP_038947479	(Get FASTA)	NCBI Sequence Viewer
	XP_038947480	(Get FASTA)	NCBI Sequence Viewer
	XP_063128859	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D3ZEY4	(Get FASTA)	NCBI Sequence Viewer
	EDL84023	(Get FASTA)	NCBI Sequence Viewer
	EDL84024	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000036466
	ENSRNOP00000036466.4
	ENSRNOP00000108077

RefSeq Acc Id:

NP_001185733 ⟸ NM_001198804

- UniProtKB:

D3ZEY4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MATAAESGARTWPGSGSPRLGSPAGSPVLGISGRARPGSGPERTGRAIGSVAPGHSFRKVTLTK
PTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKQVKTPCTSIAPSLVRVPVAHCFGSLGLYKRKF
CVVCRKSLEVPAFRCEVCELHVHPDCVPFACSDCRQCHQDGQHDYDTYHHHWREGNLPSGARCE
VCRKTCGSSDVLAGVRCEWCGVQAHSVCSTALTPECTFGRLRSMVLPPSCVRLLSRNFSKMHCF
RIPETMVLELGDGDDGLDGSAAVGTGREVSAATESTKQTLKIFDGNDSMRKNQFRLVTVSRLAR
NEEVMEAALRAYYINEDPKDFQLQALPLTLLSGNAQALGKAGTTEEETSKDSGPGDSVPEAWVI
RSLPRTQEILKIYPDWLKVGVAYVSIRVNSQSTARSVVQEVLPLFGRQVEDQERFQLIEVLMSS
RQVQRTVLVDEEPLLDRLRDIRQTSVRQASQTRFYVAEARAVTPHVSLFVGGLPPGLSPQDYSN
LLHEAMATKAAVVSVSHVYSLQGAVVLDVTCFAEAERLYMLARDTAVHGRPLTALVLPDVLHTK
LPPDCCPLLVFVNPKSGGLKGRELLCSFRKLLNPHQVFELTNGGPLPGFHLFSQVPCFRVLVCG
GDGTVGWVLAALEETRRHLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLVSVDEADA
VLMDRWTILLDAHEIDSTENNVVETEPPKIVQMNNYCGIGIDAELSLDFHQAREEEPGKFTSRF
HNKGVYVRVGLQKISHSRSLHKEIRLQVEQQEVELPSIEGLIFINIPSWGSGADLWGSDSDSRF
EKPRIDDGLLEVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWIQAPGHM
IISATAPKVHMLRKAKQKPRKAGAIRDTRVDTLPAPEGNPL

hide sequence

Ensembl Acc Id:

ENSRNOP00000036466 ⟸ ENSRNOT00000032056

RefSeq Acc Id:	XP_038947473 ⟸ XM_039091545
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038947474 ⟸ XM_039091546
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038947480 ⟸ XM_039091552
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_038947479 ⟸ XM_039091551
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038947472 ⟸ XM_039091544
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038947475 ⟸ XM_039091547
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038947477 ⟸ XM_039091549
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063128859 ⟸ XM_063272789
- Peptide Label:	isoform X6

Ensembl Acc Id:

ENSRNOP00000108077 ⟸ ENSRNOT00000155561

Protein Domains

DAGKc Ras-associating

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZEY4-F1-model_v2	AlphaFold	D3ZEY4	1-937	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699145

Promoter ID:

EPDNEW_R9669

Type:

initiation region

Name:

Dgkq_1

Description:

diacylglycerol kinase, theta

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	2,069,399 - 2,069,459	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2320722	AgrOrtholog
BioCyc Gene	G2FUF-16683	BioCyc
Ensembl Genes	ENSRNOG00000024112	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000032056	ENTREZGENE
	ENSRNOT00000032056.6	UniProtKB/Swiss-Prot
	ENSRNOT00000155561	ENTREZGENE
Gene3D-CATH	2.60.200.40	UniProtKB/Swiss-Prot
	3.30.60.20	UniProtKB/Swiss-Prot
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/Swiss-Prot
	Probable inorganic polyphosphate/atp-NAD kinase, domain 1	UniProtKB/Swiss-Prot
InterPro	ATP-NAD_kinase_N	UniProtKB/Swiss-Prot
	C1-like_sf	UniProtKB/Swiss-Prot
	DAG/PE-bd	UniProtKB/Swiss-Prot
	DGK	UniProtKB/Swiss-Prot
	DGKtheta_RBD	UniProtKB/Swiss-Prot
	Diacylglycerol_kin_accessory	UniProtKB/Swiss-Prot
	Diacylglycerol_kinase_cat_dom	UniProtKB/Swiss-Prot
	NAD/diacylglycerol_kinase_sf	UniProtKB/Swiss-Prot
	PE/DAG-bd	UniProtKB/Swiss-Prot
	RA_dom	UniProtKB/Swiss-Prot
	Ubiquitin-like_domsf	UniProtKB/Swiss-Prot
KEGG Report	rno:100361138	UniProtKB/Swiss-Prot
NCBI Gene	100361138	ENTREZGENE
PANTHER	DIACYLGLYCEROL KINASE THETA	UniProtKB/Swiss-Prot
	PTHR11255	UniProtKB/Swiss-Prot
Pfam	C1_1	UniProtKB/Swiss-Prot
	DAGK_acc	UniProtKB/Swiss-Prot
	DAGK_cat	UniProtKB/Swiss-Prot
	PF00788	UniProtKB/Swiss-Prot
	RBD_DGKtheta	UniProtKB/Swiss-Prot
PhenoGen	Dgkq	PhenoGen
PRINTS	DAGPEDOMAIN	UniProtKB/Swiss-Prot
PROSITE	DAGK	UniProtKB/Swiss-Prot
	PS50200	UniProtKB/Swiss-Prot
	ZF_DAG_PE_1	UniProtKB/Swiss-Prot
	ZF_DAG_PE_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000024112	RatGTEx
SMART	DAGKa	UniProtKB/Swiss-Prot
	DAGKc	UniProtKB/Swiss-Prot
	SM00109	UniProtKB/Swiss-Prot
	SM00314	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF111331	UniProtKB/Swiss-Prot
	SSF54236	UniProtKB/Swiss-Prot
	SSF57889	UniProtKB/Swiss-Prot
UniProt	D3ZEY4	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-08-10	Dgkq	diacylglycerol kinase, theta	LOC100361138	diacylglycerol kinase, theta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-05	LOC100361138	diacylglycerol kinase, theta			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)