Klf3 (KLF transcription factor 3) - Rat Genome Database

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Pathways
Gene: Klf3 (KLF transcription factor 3) Rattus norvegicus
Analyze
Symbol: Klf3
Name: KLF transcription factor 3
RGD ID: 1593290
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to endothelin. Predicted to be located in nucleoplasm. Orthologous to human KLF3 (KLF transcription factor 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Basic Kruppel- like factor; BKLF; Klf3_mapped; Krueppel-like factor 3; Kruppel like factor 3; Kruppel-like factor 3; Kruppel-like factor 3 (basic); Kruppel-like factor 3 (basic) (mapped); Tef-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,828,387 - 43,859,418 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1443,828,387 - 43,850,826 (-)EnsemblGRCr8
mRatBN7.21443,474,767 - 43,505,801 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1443,474,767 - 43,497,209 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1443,834,454 - 43,856,860 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01445,134,418 - 45,156,822 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01443,614,583 - 43,636,986 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01445,142,769 - 45,173,753 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,142,769 - 45,165,207 (-)Ensemblrn6Rnor6.0
Rnor_5.01444,952,288 - 44,975,148 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41446,203,638 - 46,226,077 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1442,618,174 - 42,640,598 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amosite asbestos  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diuron  (EXP)
dorsomorphin  (ISO)
epoxiconazole  (ISO)
fenamidone  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
geraniol  (ISO)
glafenine  (EXP)
GSK-J4  (ISO)
isoprenaline  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (EXP)
p-toluidine  (EXP)
paracetamol  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Differential regulation of Kruppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. Cullingford TE, etal., Biochim Biophys Acta. 2008 Jun;1783(6):1229-36. Epub 2008 Mar 25.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat. Szpirer C, etal., Mamm Genome 2000 Sep;11(9):729-35
Additional References at PubMed
PMID:18687676   PMID:22115574   PMID:39250818  


Genomics

Comparative Map Data
Klf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,828,387 - 43,859,418 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1443,828,387 - 43,850,826 (-)EnsemblGRCr8
mRatBN7.21443,474,767 - 43,505,801 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1443,474,767 - 43,497,209 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1443,834,454 - 43,856,860 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01445,134,418 - 45,156,822 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01443,614,583 - 43,636,986 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01445,142,769 - 45,173,753 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,142,769 - 45,165,207 (-)Ensemblrn6Rnor6.0
Rnor_5.01444,952,288 - 44,975,148 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41446,203,638 - 46,226,077 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1442,618,174 - 42,640,598 (-)NCBICelera
Cytogenetic Map14p11NCBI
KLF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38438,664,199 - 38,701,517 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl438,664,032 - 38,701,517 (+)Ensemblhg38GRCh38
GRCh37438,665,820 - 38,703,138 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36438,342,185 - 38,379,524 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34438,488,388 - 38,522,964NCBI
Celera439,107,001 - 39,144,340 (+)NCBICelera
Cytogenetic Map4p14NCBI
HuRef437,989,129 - 38,026,462 (+)NCBIHuRef
CHM1_1438,664,914 - 38,702,230 (+)NCBICHM1_1
T2T-CHM13v2.0438,633,299 - 38,670,624 (+)NCBIT2T-CHM13v2.0
Klf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39564,960,864 - 64,990,246 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl564,960,731 - 64,990,244 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38564,803,521 - 64,832,901 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl564,803,388 - 64,832,901 (+)Ensemblmm10GRCm38
MGSCv37565,194,762 - 65,221,368 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36565,082,658 - 65,109,264 (+)NCBIMGSCv36mm8
Celera562,088,896 - 62,102,287 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.49NCBI
Klf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554438,525,510 - 8,548,499 (-)Ensembl
ChiLan1.0NW_0049554438,526,371 - 8,549,510 (-)NCBIChiLan1.0ChiLan1.0
KLF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2338,852,350 - 38,889,452 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1439,044,844 - 39,078,485 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0432,992,702 - 33,029,420 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1438,846,989 - 38,883,480 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl438,846,989 - 38,883,480 (+)EnsemblpanPan2panpan1.1
KLF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1373,627,112 - 73,663,702 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl373,629,312 - 73,664,182 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha376,174,252 - 76,210,837 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0374,406,717 - 74,443,317 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl374,406,721 - 74,427,853 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1373,673,626 - 73,710,207 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0373,819,087 - 73,855,660 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0374,200,168 - 74,236,753 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528539,781,800 - 39,814,423 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364826,483,806 - 6,517,117 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364826,483,813 - 6,516,435 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,024,799 - 30,060,974 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1830,024,978 - 30,060,981 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2831,493,372 - 31,537,659 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12711,602,579 - 11,640,329 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2711,601,989 - 11,640,455 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604758,011,242 - 58,048,883 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248407,181,069 - 7,204,865 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248407,172,838 - 7,204,783 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Klf3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11121,822,611 - 21,853,060 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Klf3
164 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:632
Count of miRNA genes:268
Interacting mature miRNAs:361
Transcripts:ENSRNOT00000002960
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143123808072970315Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142252151767521517Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141889519263895192Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141790672654251504Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat

Markers in Region
RH141772  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,478,098 - 43,478,316 (+)MAPPERmRatBN7.2
Rnor_6.01445,146,101 - 45,146,317NCBIRnor6.0
Rnor_5.01444,955,620 - 44,955,836UniSTSRnor5.0
RGSC_v3.41446,206,970 - 46,207,187UniSTSRGSC3.4
Celera1442,621,506 - 42,621,723UniSTS
Cytogenetic Map14p11UniSTS
Klf3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,478,488 - 43,478,669 (+)MAPPERmRatBN7.2
Rnor_6.01445,146,489 - 45,146,669NCBIRnor6.0
Rnor_5.01444,956,008 - 44,956,188UniSTSRnor5.0
RGSC_v3.41446,207,359 - 46,207,539UniSTSRGSC3.4
Celera1442,621,895 - 42,622,075UniSTS
Cytogenetic Map14p11UniSTS
RH129353  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,474,897 - 43,475,116 (+)MAPPERmRatBN7.2
Rnor_6.01445,142,900 - 45,143,118NCBIRnor6.0
Rnor_5.01444,952,419 - 44,952,637UniSTSRnor5.0
RGSC_v3.41446,203,769 - 46,203,987UniSTSRGSC3.4
Celera1442,618,305 - 42,618,523UniSTS
Cytogenetic Map14p11UniSTS
RH142658  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,495,782 - 43,495,882 (+)MAPPERmRatBN7.2
Rnor_6.01445,163,781 - 45,163,880NCBIRnor6.0
Rnor_5.01444,973,300 - 44,973,399UniSTSRnor5.0
RGSC_v3.41446,224,651 - 46,224,750UniSTSRGSC3.4
Celera1442,639,172 - 42,639,271UniSTS
Cytogenetic Map14p11UniSTS
RH143210  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,475,711 - 43,475,873 (+)MAPPERmRatBN7.2
Rnor_6.01445,143,714 - 45,143,875NCBIRnor6.0
Rnor_5.01444,953,233 - 44,953,394UniSTSRnor5.0
RGSC_v3.41446,204,583 - 46,204,744UniSTSRGSC3.4
Celera1442,619,119 - 42,619,280UniSTS
Cytogenetic Map14p11UniSTS
BF406102  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,484,084 - 43,484,281 (+)MAPPERmRatBN7.2
Rnor_6.01445,152,083 - 45,152,279NCBIRnor6.0
Rnor_5.01444,961,602 - 44,961,798UniSTSRnor5.0
RGSC_v3.41446,212,953 - 46,213,149UniSTSRGSC3.4
Celera1442,627,489 - 42,627,685UniSTS
Cytogenetic Map14p11UniSTS
RH138428  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,477,584 - 43,477,756 (+)MAPPERmRatBN7.2
Rnor_6.01445,145,587 - 45,145,758NCBIRnor6.0
Rnor_5.01444,955,106 - 44,955,277UniSTSRnor5.0
RGSC_v3.41446,206,456 - 46,206,627UniSTSRGSC3.4
Celera1442,620,992 - 42,621,163UniSTS
RH 3.4 Map6779.5UniSTS
Cytogenetic Map14p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002960   ⟹   ENSRNOP00000002960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1443,828,387 - 43,850,826 (-)Ensembl
mRatBN7.2 Ensembl1443,474,767 - 43,497,209 (-)Ensembl
Rnor_6.0 Ensembl1445,142,769 - 45,165,207 (-)Ensembl
RefSeq Acc Id: NM_001105742   ⟹   NP_001099212
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,828,387 - 43,850,826 (-)NCBI
mRatBN7.21443,474,767 - 43,497,209 (-)NCBI
Rnor_6.01445,142,769 - 45,165,207 (-)NCBI
Rnor_5.01444,952,288 - 44,975,148 (-)NCBI
RGSC_v3.41446,203,638 - 46,226,077 (-)RGD
Celera1442,618,174 - 42,640,598 (-)RGD
Sequence:
RefSeq Acc Id: XM_006250995   ⟹   XP_006251057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,828,388 - 43,851,274 (-)NCBI
mRatBN7.21443,474,768 - 43,497,631 (-)NCBI
Rnor_6.01445,142,770 - 45,166,133 (-)NCBI
Rnor_5.01444,952,288 - 44,975,148 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770134   ⟹   XP_008768356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,828,388 - 43,859,418 (-)NCBI
mRatBN7.21443,474,768 - 43,505,801 (-)NCBI
Rnor_6.01445,142,770 - 45,173,753 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005492873
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,834,958 - 43,859,418 (-)NCBI
mRatBN7.21443,481,336 - 43,505,801 (-)NCBI
RefSeq Acc Id: NP_001099212   ⟸   NM_001105742
- UniProtKB: D4A4V3 (UniProtKB/TrEMBL),   A6JDG0 (UniProtKB/TrEMBL),   A6JDG1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251057   ⟸   XM_006250995
- Peptide Label: isoform X1
- UniProtKB: D4A4V3 (UniProtKB/TrEMBL),   A6JDG0 (UniProtKB/TrEMBL),   A6JDG1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768356   ⟸   XM_008770134
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000002960   ⟸   ENSRNOT00000002960
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4V3-F1-model_v2 AlphaFold D4A4V3 1-344 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699320
Promoter ID:EPDNEW_R9845
Type:initiation region
Name:Klf3_1
Description:Kruppel like factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01445,165,177 - 45,165,237EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593290 AgrOrtholog
BioCyc Gene G2FUF-15724 BioCyc
Ensembl Genes ENSRNOG00000002163 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002960 ENTREZGENE
  ENSRNOT00000002960.8 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:114845 UniProtKB/TrEMBL
NCBI Gene 114845 ENTREZGENE
PANTHER KRUEPPEL-LIKE FACTOR 3 UniProtKB/TrEMBL
  KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Klf3 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002163 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A6JDG0 ENTREZGENE, UniProtKB/TrEMBL
  A6JDG1 ENTREZGENE, UniProtKB/TrEMBL
  A6JDG2_RAT UniProtKB/TrEMBL
  D4A4V3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-03 Klf3  KLF transcription factor 3  Klf3  Kruppel like factor 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-06-08 Klf3  Kruppel like factor 3  Klf3  Kruppel-like factor 3 (basic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   Kruppel-like factor 3 (basic)  Klf3  Kruppel-like factor 3 (basic) (mapped)  Name updated 737654 APPROVED
2007-04-13 Klf3  Kruppel-like factor 3 (basic) (mapped)  Klf3_mapped  Kruppel-like factor 3 (basic) (mapped)  Data merged from RGD:69060 737654 APPROVED
2006-11-20 Klf3  Kruppel-like factor 3 (basic) (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Klf3_mapped  Kruppel-like factor 3 (basic) (mapped)  Klf3  Kruppel-like factor 3 (basic)  Symbol and Name updated 1556543 APPROVED
2004-09-10 Klf3  Kruppel-like factor 3 (basic)    Kruppel-like factor 3  Name updated 1299863 APPROVED
2002-06-10 Klf3  Kruppel-like factor 3      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference