Hao1 (hydroxyacid oxidase 1) - Rat Genome Database

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Gene: Hao1 (hydroxyacid oxidase 1) Rattus norvegicus
Analyze
Symbol: Hao1
Name: hydroxyacid oxidase 1
RGD ID: 1589750
Description: Predicted to enable (S)-2-hydroxy-acid oxidase activity; FMN binding activity; and glyoxylate oxidase activity. Involved in response to oxidative stress. Located in peroxisome. Orthologous to human HAO1 (hydroxyacid oxidase 1); PARTICIPATES IN glyoxylate and dicarboxylate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2-Hydroxyacid oxidase 1; glycolate oxidase; glyoxylate oxidase; GOX; Gox1; Hao1_mapped; HAOX1; hydroxyacid oxidase (glycolate oxidase) 1; hydroxyacid oxidase 1 (mapped); hydroxyacid oxidase 1, liver; XDH1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83142,102,873 - 142,281,527 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3142,224,612 - 142,281,494 (-)EnsemblGRCr8
mRatBN7.23121,757,400 - 121,828,721 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3121,771,836 - 121,828,721 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3125,674,380 - 125,731,284 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03134,287,471 - 134,345,573 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03131,930,568 - 131,987,464 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03127,444,900 - 127,500,709 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3127,444,902 - 127,500,709 (-)Ensemblrn6Rnor6.0
Rnor_5.03133,932,667 - 133,988,954 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43122,506,916 - 122,564,012 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3120,530,658 - 120,586,825 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
peroxisomal matrix  (IEA,ISO)
peroxisome  (IDA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases. Jones JM, etal., J Biol Chem. 2000 Apr 28;275(17):12590-7. doi: 10.1074/jbc.275.17.12590.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Oxidative stress-mediated down-regulation of rat hydroxyacid oxidase 1, a liver-specific peroxisomal enzyme. Recalcati S, etal., Hepatology 2003 Nov;38(5):1159-66.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1300399   PMID:4818266   PMID:12477932   PMID:14561759   PMID:17669354   PMID:18215067   PMID:19758989   PMID:20178365  


Genomics

Comparative Map Data
Hao1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83142,102,873 - 142,281,527 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3142,224,612 - 142,281,494 (-)EnsemblGRCr8
mRatBN7.23121,757,400 - 121,828,721 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3121,771,836 - 121,828,721 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3125,674,380 - 125,731,284 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03134,287,471 - 134,345,573 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03131,930,568 - 131,987,464 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03127,444,900 - 127,500,709 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3127,444,902 - 127,500,709 (-)Ensemblrn6Rnor6.0
Rnor_5.03133,932,667 - 133,988,954 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43122,506,916 - 122,564,012 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3120,530,658 - 120,586,825 (-)NCBICelera
Cytogenetic Map3q36NCBI
HAO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38207,882,985 - 7,940,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl207,882,985 - 7,940,520 (-)Ensemblhg38GRCh38
GRCh37207,863,632 - 7,921,105 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36207,811,631 - 7,869,093 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34207,811,630 - 7,869,093NCBI
Celera207,933,209 - 7,990,669 (-)NCBICelera
Cytogenetic Map20p12.3NCBI
HuRef207,814,621 - 7,872,059 (-)NCBIHuRef
CHM1_1207,864,109 - 7,921,570 (-)NCBICHM1_1
T2T-CHM13v2.0207,924,797 - 7,982,271 (-)NCBIT2T-CHM13v2.0
Hao1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392134,339,281 - 134,396,272 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2134,339,281 - 134,396,288 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382134,497,361 - 134,554,352 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2134,497,361 - 134,554,368 (-)Ensemblmm10GRCm38
MGSCv372134,323,097 - 134,380,088 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362134,188,802 - 134,245,793 (-)NCBIMGSCv36mm8
Celera2135,711,108 - 135,768,145 (-)NCBICelera
Cytogenetic Map2F2NCBI
cM Map265.65NCBI
Hao1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541517,981,791 - 18,035,224 (-)Ensembl
ChiLan1.0NW_00495541517,981,791 - 18,035,151 (-)NCBIChiLan1.0ChiLan1.0
HAO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2218,784,614 - 8,842,467 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1208,781,441 - 8,839,294 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0207,856,967 - 7,914,818 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1207,637,582 - 7,695,120 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl207,633,861 - 7,695,120 (-)EnsemblpanPan2panpan1.1
HAO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12414,204,543 - 14,252,873 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2414,204,617 - 14,252,191 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2414,026,777 - 14,075,130 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02414,605,063 - 14,653,411 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2414,605,124 - 14,653,421 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12414,214,061 - 14,262,313 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02414,324,157 - 14,372,478 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02414,653,607 - 14,701,967 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hao1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640163,001,985 - 163,055,075 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648511,435,151 - 11,486,042 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648511,435,151 - 11,486,042 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HAO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1716,744,442 - 16,802,442 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11716,746,153 - 16,802,460 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21718,814,432 - 18,870,834 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HAO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1230,183,031 - 30,238,663 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl230,183,705 - 30,240,231 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607114,314,987 - 14,370,752 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hao1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247418,763,496 - 8,824,468 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247418,762,556 - 8,824,517 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hao1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15114,194,421 - 114,250,905 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hao1
891 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:32
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000006330
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
RH139736  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23121,771,374 - 121,771,583 (+)MAPPERmRatBN7.2
Rnor_6.03127,444,441 - 127,444,649NCBIRnor6.0
Rnor_5.03133,932,686 - 133,932,894UniSTSRnor5.0
RGSC_v3.43122,506,457 - 122,506,665UniSTSRGSC3.4
Celera3120,530,199 - 120,530,407UniSTS
RH 3.4 Map31065.8UniSTS
Cytogenetic Map3q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
2 8 17 60 77 74 53 24 53 3 191 66 9 41 63 42 21 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000006330   ⟹   ENSRNOP00000006330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3142,224,612 - 142,281,494 (-)Ensembl
mRatBN7.2 Ensembl3121,771,836 - 121,828,721 (-)Ensembl
Rnor_6.0 Ensembl3127,444,902 - 127,500,709 (-)Ensembl
RefSeq Acc Id: NM_001107780   ⟹   NP_001101250
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83142,224,610 - 142,281,494 (-)NCBI
mRatBN7.23121,771,834 - 121,828,721 (-)NCBI
Rnor_6.03127,444,900 - 127,500,709 (-)NCBI
Rnor_5.03133,932,667 - 133,988,954 (-)NCBI
RGSC_v3.43122,506,916 - 122,564,012 (-)RGD
Celera3120,530,658 - 120,586,825 (-)RGD
Sequence:
RefSeq Acc Id: XM_039105017   ⟹   XP_038960945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83142,210,171 - 142,281,482 (-)NCBI
mRatBN7.23121,757,400 - 121,828,708 (-)NCBI
RefSeq Acc Id: XM_063283785   ⟹   XP_063139855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83142,102,873 - 142,281,527 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101250 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960945 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139855 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58805 (Get FASTA)   NCBI Sequence Viewer  
  B0BNF9 (Get FASTA)   NCBI Sequence Viewer  
  EDL80285 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006330
  ENSRNOP00000006330.3
RefSeq Acc Id: NP_001101250   ⟸   NM_001107780
- UniProtKB: B0BNF9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006330   ⟸   ENSRNOT00000006330
RefSeq Acc Id: XP_038960945   ⟸   XM_039105017
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063139855   ⟸   XM_063283785
- Peptide Label: isoform X1
Protein Domains
FMN hydroxy acid dehydrogenase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BNF9-F1-model_v2 AlphaFold B0BNF9 1-370 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692462
Promoter ID:EPDNEW_R2985
Type:multiple initiation site
Name:Hao1_1
Description:hydroxyacid oxidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03127,500,726 - 127,500,786EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589750 AgrOrtholog
BioCyc Gene G2FUF-47744 BioCyc
Ensembl Genes ENSRNOG00000004601 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006330 ENTREZGENE
  ENSRNOT00000006330.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7322008 IMAGE-MGC_LOAD
InterPro Aldolase_TIM UniProtKB/Swiss-Prot
  Alpha-hydoxy_acid_DH_FMN UniProtKB/Swiss-Prot
  FMN-dep_DH UniProtKB/Swiss-Prot
  FMN_HAD UniProtKB/Swiss-Prot
  FMN_hydac_DH_AS UniProtKB/Swiss-Prot
KEGG Report rno:311446 UniProtKB/Swiss-Prot
MGC_CLONE MGC:188217 IMAGE-MGC_LOAD
NCBI Gene 311446 ENTREZGENE
PANTHER 2-HYDROXYACID OXIDASE 1 UniProtKB/Swiss-Prot
  S -2-HYDROXY-ACID OXIDASE-RELATED UniProtKB/Swiss-Prot
Pfam FMN_dh UniProtKB/Swiss-Prot
PhenoGen Hao1 PhenoGen
PIRSF Al-hdrx_acd_dh UniProtKB/Swiss-Prot
PROSITE FMN_HYDROXY_ACID_DH_1 UniProtKB/Swiss-Prot
  FMN_HYDROXY_ACID_DH_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004601 RatGTEx
Superfamily-SCOP FMN-linked oxidoreductases UniProtKB/Swiss-Prot
UniProt B0BNF9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-29 Hao1  hydroxyacid oxidase 1  Hao1  hydroxyacid oxidase (glycolate oxidase) 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-05-22 Hao1  hydroxyacid oxidase (glycolate oxidase) 1  Hao1  hydroxyacid oxidase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-02-26 Hao1  hydroxyacid oxidase 1  Hao1  hydroxyacid oxidase 1, liver  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Hao1  hydroxyacid oxidase 1, liver  Hao1  hydroxyacid oxidase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   hydroxyacid oxidase 1  Hao1  hydroxyacid oxidase 1 (mapped)  Name updated 737654 APPROVED
2007-04-11 Hao1  hydroxyacid oxidase 1 (mapped)  Hao1_mapped  hydroxyacid oxidase 1 (mapped)  Data merged from RGD:2780 737654 APPROVED
2006-11-19 Hao1  hydroxyacid oxidase 1 (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Hao1_mapped  hydroxyacid oxidase 1 (mapped)      Symbol and Name updated 1556543 APPROVED
2002-06-10 Hao1  hydroxyacid oxidase 1      Symbol and Name status set to approved 70586 APPROVED
2001-04-19 Gox1  Glycolate Oxidase 1      Symbol withdrawn, duplicate entry of Hao1 (RGD:2780) 61478 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_expression expressed specifically in liver 1300399