Rgs16 (regulator of G-protein signaling 16) - Rat Genome Database

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Gene: Rgs16 (regulator of G-protein signaling 16) Rattus norvegicus
Analyze
Symbol: Rgs16
Name: regulator of G-protein signaling 16
RGD ID: 1589741
Description: Predicted to enable GTPase activator activity. Predicted to be involved in G protein-coupled receptor signaling pathway and positive regulation of GTPase activity. Predicted to be located in cytoplasm and membrane. Orthologous to human RGS16 (regulator of G protein signaling 16); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: regulator of G-protein signaling 16 (mapped); retinal-specific RGS; retinally abundant regulator of G-protein signaling; RGS-R; Rgs16_mapped
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81368,421,480 - 68,443,312 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1368,438,120 - 68,443,313 (+)EnsemblGRCr8
mRatBN7.21365,887,668 - 65,892,862 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1365,887,530 - 65,892,857 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1368,488,860 - 68,492,298 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01369,779,050 - 69,782,494 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01367,032,029 - 67,035,429 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01371,163,411 - 71,185,147 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1371,179,910 - 71,185,216 (+)Ensemblrn6Rnor6.0
Rnor_5.01376,128,653 - 76,150,399 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41368,807,863 - 68,811,307 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1365,788,298 - 65,791,737 (+)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-colchicine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrolein  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
adenine  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzoates  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
curcumin  (ISO)
cyanocob(III)alamin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
fenofibrate  (EXP)
fenthion  (ISO)
fentin chloride  (EXP)
ferric oxide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
gardiquimod  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glycine betaine  (ISO)
glyphosate  (EXP)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
hydroxyurea  (ISO)
imidacloprid  (EXP)
indole-3-methanol  (EXP)
inulin  (ISO)
itraconazole  (ISO)
kainic acid  (ISO)
ketoconazole  (ISO)
L-methionine  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (EXP,ISO)
manganese(II) chloride  (EXP)
melphalan  (ISO)
menadione  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
mitomycin C  (ISO)
Moniliformin  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N(6)-dimethylallyladenine  (ISO)
N-acetyl-L-cysteine  (EXP)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
naphthalene  (ISO)
nevirapine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosgene  (ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
propiconazole  (ISO)
protein kinase inhibitor  (ISO)
raloxifene  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulfasalazine  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
theophylline  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zaragozic acid A  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
GTPase activator activity  (IBA,IEA,ISO,ISS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Palmitoylation regulates regulators of G-protein signaling (RGS) 16 function. I. Mutation of amino-terminal cysteine residues on RGS16 prevents its targeting to lipid rafts and palmitoylation of an internal cysteine residue. Hiol A, etal., J Biol Chem 2003 May 23;278(21):19301-8. Epub 2003 Mar 17.
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1300469   PMID:8917514   PMID:10373502   PMID:10791963   PMID:15793568   PMID:15946253   PMID:18434541   PMID:19374869   PMID:19588733  


Genomics

Comparative Map Data
Rgs16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81368,421,480 - 68,443,312 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1368,438,120 - 68,443,313 (+)EnsemblGRCr8
mRatBN7.21365,887,668 - 65,892,862 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1365,887,530 - 65,892,857 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1368,488,860 - 68,492,298 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01369,779,050 - 69,782,494 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01367,032,029 - 67,035,429 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01371,163,411 - 71,185,147 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1371,179,910 - 71,185,216 (+)Ensemblrn6Rnor6.0
Rnor_5.01376,128,653 - 76,150,399 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41368,807,863 - 68,811,307 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1365,788,298 - 65,791,737 (+)NCBICelera
Cytogenetic Map13q21NCBI
RGS16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381182,598,623 - 182,604,389 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1182,598,623 - 182,604,394 (-)Ensemblhg38GRCh38
GRCh371182,567,758 - 182,573,524 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361180,834,381 - 180,840,171 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341179,299,415 - 179,305,200NCBI
Celera1155,678,992 - 155,684,782 (-)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1153,804,224 - 153,810,014 (-)NCBIHuRef
CHM1_11183,991,292 - 183,997,081 (-)NCBICHM1_1
T2T-CHM13v2.01181,958,121 - 181,963,886 (-)NCBIT2T-CHM13v2.0
Rgs16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,616,099 - 153,621,212 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,616,095 - 153,621,214 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381153,740,353 - 153,745,468 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,740,349 - 153,745,468 (+)Ensemblmm10GRCm38
MGSCv371155,587,483 - 155,592,598 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361155,502,566 - 155,507,684 (+)NCBIMGSCv36mm8
Celera1156,172,183 - 156,177,294 (+)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.43NCBI
Rgs16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540621,439,272 - 21,445,038 (-)Ensembl
ChiLan1.0NW_00495540621,439,536 - 21,444,822 (-)NCBIChiLan1.0ChiLan1.0
RGS16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2167,124,524 - 67,130,751 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,808,016 - 66,814,241 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,117,257 - 158,123,031 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,768,921 - 161,774,709 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,765,595 - 161,774,709 (-)EnsemblpanPan2panpan1.1
RGS16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1716,009,283 - 16,015,228 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl716,009,271 - 16,015,597 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha715,595,717 - 15,601,663 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0715,738,716 - 15,744,653 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl715,739,616 - 15,744,690 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1715,650,339 - 15,656,274 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0715,758,624 - 15,764,560 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0715,887,673 - 15,893,854 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rgs16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934489,300,380 - 89,305,804 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364817,147,013 - 7,152,565 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364817,147,147 - 7,152,555 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9123,913,173 - 123,918,871 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19123,913,179 - 123,919,119 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29136,173,524 - 136,175,853 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RGS16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12546,764,097 - 46,769,895 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2546,764,134 - 46,769,896 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605547,982,051 - 47,987,847 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462481411,249,335 - 11,255,113 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462481411,249,448 - 11,254,728 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rgs16
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11033,192,082 - 33,197,341 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rgs16
150 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:64
Count of miRNA genes:56
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000032236
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 354 192 11 141 79 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000032236   ⟹   ENSRNOP00000029844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1368,438,120 - 68,443,313 (+)Ensembl
mRatBN7.2 Ensembl1365,887,530 - 65,892,857 (+)Ensembl
Rnor_6.0 Ensembl1371,179,910 - 71,185,216 (+)Ensembl
RefSeq Acc Id: NM_001077589   ⟹   NP_001071057
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81368,438,120 - 68,443,312 (+)NCBI
mRatBN7.21365,887,668 - 65,892,862 (+)NCBI
Rnor_6.01371,180,078 - 71,183,522 (+)NCBI
Rnor_5.01376,128,653 - 76,150,399 (+)NCBI
RGSC_v3.41368,807,863 - 68,811,307 (+)RGD
Celera1365,788,298 - 65,791,737 (+)RGD
Sequence:
RefSeq Acc Id: XM_063272477   ⟹   XP_063128547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81368,421,480 - 68,443,300 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001071057 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128547 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAV85502 (Get FASTA)   NCBI Sequence Viewer  
  EDM09539 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000029844
GenBank Protein P56700 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001071057   ⟸   NM_001077589
- UniProtKB: P56700 (UniProtKB/Swiss-Prot),   Q4L0E9 (UniProtKB/TrEMBL),   F7FDE5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029844   ⟸   ENSRNOT00000032236
RefSeq Acc Id: XP_063128547   ⟸   XM_063272477
- Peptide Label: isoform X1
- UniProtKB: P56700 (UniProtKB/Swiss-Prot),   F7FDE5 (UniProtKB/TrEMBL),   Q4L0E9 (UniProtKB/TrEMBL)
Protein Domains
RGS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P56700-F1-model_v2 AlphaFold P56700 1-199 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698899
Promoter ID:EPDNEW_R9424
Type:single initiation site
Name:Rgs16_1
Description:regulator of G-protein signaling 16
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01371,179,958 - 71,180,018EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589741 AgrOrtholog
BioCyc Gene G2FUF-17877 BioCyc
Ensembl Genes ENSRNOG00000027024 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000032236 ENTREZGENE
Gene3D-CATH 1.10.167.10 UniProtKB/Swiss-Prot
  1.10.196.10 UniProtKB/Swiss-Prot
InterPro RGS UniProtKB/Swiss-Prot
  RGS_sf UniProtKB/Swiss-Prot
  RGS_subdom1/3 UniProtKB/Swiss-Prot
  RGS_subdomain_2 UniProtKB/Swiss-Prot
NCBI Gene 360857 ENTREZGENE
PANTHER REGULATOR OF G PROTEIN SIGNALING UniProtKB/Swiss-Prot
  REGULATOR OF G-PROTEIN SIGNALING 16 UniProtKB/Swiss-Prot
Pfam RGS UniProtKB/Swiss-Prot
PhenoGen Rgs16 PhenoGen
PRINTS RGSPROTEIN UniProtKB/Swiss-Prot
PROSITE RGS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000027024 RatGTEx
SMART RGS UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48097 UniProtKB/Swiss-Prot
UniProt F7FDE5 ENTREZGENE, UniProtKB/TrEMBL
  P56700 ENTREZGENE
  Q4L0E9 ENTREZGENE, UniProtKB/TrEMBL
  RGS16_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2007-04-12 Rgs16  regulator of G-protein signaling 16  Rgs16_mapped  regulator of G-protein signaling 16 (mapped)  Data merged from RGD:3565 737654 APPROVED
2006-11-19 Rgs16_mapped  regulator of G-protein signaling 16(mapped)  Rgs16  regulator of G-protein signaling 16  Symbol set to symbol_mapped, name set to name (mapped) 1582166 APPROVED
2006-11-19 Rgs16  regulator of G-protein signaling 16      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Rgs16  Regulator of G-protein signaling 16      Symbol and Name status set to approved 70586 APPROVED