Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Echdc3 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ECHDC3 mRNA] | CTD | PMID:31150632 | Echdc3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Echdc3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ECHDC3 mRNA | CTD | PMID:36331819 | Echdc3 | Rat | 1,2-dichloroethane | increases expression | ISO | Echdc3 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of ECHDC3 mRNA | CTD | PMID:28960355 | Echdc3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of ECHDC3 mRNA | CTD | PMID:22206623 | Echdc3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Echdc3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECHDC3 mRNA | CTD | PMID:22206623 | Echdc3 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Echdc3 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of ECHDC3 mRNA | CTD | PMID:17555576 | Echdc3 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Echdc3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ECHDC3 mRNA | CTD | PMID:17942748 | Echdc3 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of ECHDC3 mRNA | CTD | PMID:17942748 | Echdc3 | Rat | 17beta-estradiol | multiple interactions | ISO | ECHDC3 (Homo sapiens) | 6480464 | [Estradiol co-treated with Norethindrone Acetate] results in increased expression of ECHDC3 mRNA | CTD | PMID:22217510 | Echdc3 | Rat | 17beta-estradiol | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Estradiol results in decreased expression of ECHDC3 mRNA | CTD | PMID:39298647 | Echdc3 | Rat | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of ECHDC3 protein | CTD | PMID:32145629 | Echdc3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Echdc3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ECHDC3 mRNA | CTD | PMID:21570461 | Echdc3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ECHDC3 mRNA | CTD | PMID:33387578 | Echdc3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ECHDC3 mRNA | CTD | PMID:32109520 | Echdc3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ECHDC3 mRNA | CTD | PMID:17942748 | Echdc3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Echdc3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ECHDC3 mRNA | CTD | PMID:17942748 | Echdc3 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of ECHDC3 mRNA | CTD | PMID:39298647 | Echdc3 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Echdc3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of ECHDC3 gene | CTD | PMID:31683443 | Echdc3 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | Echdc3 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of ECHDC3 promoter | CTD | PMID:33297965 | Echdc3 | Rat | 4-hydroxynon-2-enal | increases expression | ISO | Echdc3 (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in increased expression of ECHDC3 mRNA | CTD | PMID:19191707 | Echdc3 | Rat | 5-fluorouracil | affects response to substance | ISO | ECHDC3 (Homo sapiens) | 6480464 | ECHDC3 protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | Echdc3 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ECHDC3 mRNA | CTD | PMID:24780913 | Echdc3 | Rat | acrylamide | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of ECHDC3 mRNA | CTD | PMID:32763439 | Echdc3 | Rat | aflatoxin B1 | affects expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ECHDC3 protein | CTD | PMID:20106945 | Echdc3 | Rat | all-trans-retinoic acid | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ECHDC3 mRNA | CTD | PMID:23724009 | Echdc3 | Rat | avobenzone | increases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | avobenzone results in increased expression of ECHDC3 mRNA | CTD | PMID:31016361 | Echdc3 | Rat | benzo[a]pyrene | multiple interactions | ISO | Echdc3 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ECHDC3 mRNA] | CTD | PMID:22228805 | Echdc3 | Rat | benzo[a]pyrene | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ECHDC3 mRNA | CTD | PMID:32234424 | Echdc3 | Rat | benzo[a]pyrene | increases methylation | ISO | ECHDC3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ECHDC3 promoter | CTD | PMID:27901495 | Echdc3 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of ECHDC3 mRNA | CTD | PMID:34319233 | Echdc3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ECHDC3 mRNA | CTD | PMID:25181051 | Echdc3 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ECHDC3 protein | CTD | PMID:32145629 | Echdc3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ECHDC3 mRNA | CTD | PMID:30816183|PMID:32145629 | Echdc3 | Rat | bisphenol AF | increases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of ECHDC3 protein | CTD | PMID:34186270 | Echdc3 | Rat | Bisphenol B | increases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of ECHDC3 protein | CTD | PMID:34186270 | Echdc3 | Rat | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of ECHDC3 mRNA | CTD | PMID:24136188 | Echdc3 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Echdc3 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of ECHDC3 intron | CTD | PMID:28392331 | Echdc3 | Rat | cadmium atom | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Cadmium results in decreased expression of ECHDC3 mRNA | CTD | PMID:24067728 | Echdc3 | Rat | carbon nanotube | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of ECHDC3 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681|PMID:25620056 | Echdc3 | Rat | chlordecone | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of ECHDC3 mRNA | CTD | PMID:33711761 | Echdc3 | Rat | chromium(6+) | affects expression | ISO | Echdc3 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of ECHDC3 mRNA | CTD | PMID:28472532 | Echdc3 | Rat | clofibrate | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of ECHDC3 mRNA | CTD | PMID:23811191 | Echdc3 | Rat | cyclosporin A | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ECHDC3 mRNA | CTD | PMID:20106945 | Echdc3 | Rat | DDE | increases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of ECHDC3 mRNA | CTD | PMID:38568856 | Echdc3 | Rat | Dibutyl phosphate | affects expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ECHDC3 mRNA | CTD | PMID:37042841 | Echdc3 | Rat | dibutyl phthalate | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of ECHDC3 mRNA | CTD | PMID:21266533 | Echdc3 | Rat | dorsomorphin | multiple interactions | ISO | ECHDC3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Echdc3 | Rat | fenthion | increases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Fenthion results in increased expression of ECHDC3 mRNA | CTD | PMID:34813904 | Echdc3 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of ECHDC3 mRNA | CTD | PMID:26485406 | Echdc3 | Rat | folic acid | multiple interactions | ISO | Echdc3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ECHDC3 mRNA | CTD | PMID:22206623 | Echdc3 | Rat | fonofos | increases methylation | ISO | ECHDC3 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of ECHDC3 promoter | CTD | PMID:22847954 | Echdc3 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of ECHDC3 mRNA | CTD | PMID:24136188 | Echdc3 | Rat | glyphosate | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of ECHDC3 protein | CTD | PMID:36173347 | Echdc3 | Rat | inulin | multiple interactions | ISO | Echdc3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ECHDC3 mRNA | CTD | PMID:36331819 | Echdc3 | Rat | methamphetamine | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Methamphetamine results in decreased expression of ECHDC3 mRNA | CTD | PMID:26307267 | Echdc3 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of ECHDC3 mRNA | CTD | PMID:30467583 | Echdc3 | Rat | nickel atom | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Nickel results in decreased expression of ECHDC3 mRNA | CTD | PMID:25583101 | Echdc3 | Rat | nickel sulfate | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of ECHDC3 mRNA | CTD | PMID:22714537 | Echdc3 | Rat | okadaic acid | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of ECHDC3 mRNA | CTD | PMID:38832940 | Echdc3 | Rat | paracetamol | affects expression | ISO | Echdc3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ECHDC3 mRNA | CTD | PMID:17562736 | Echdc3 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ECHDC3 mRNA | CTD | PMID:33387578 | Echdc3 | Rat | paracetamol | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ECHDC3 mRNA | CTD | PMID:29067470 | Echdc3 | Rat | parathion | increases methylation | ISO | ECHDC3 (Homo sapiens) | 6480464 | Parathion results in increased methylation of ECHDC3 promoter | CTD | PMID:22847954 | Echdc3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Echdc3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ECHDC3 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Echdc3 | Rat | phenylmercury acetate | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of ECHDC3 mRNA | CTD | PMID:26272509 | Echdc3 | Rat | phenylmercury acetate | multiple interactions | ISO | ECHDC3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Echdc3 | Rat | pirinixic acid | multiple interactions | ISO | ECHDC3 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Echdc3 | Rat | pirinixic acid | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ECHDC3 mRNA | CTD | PMID:18445702 | Echdc3 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of ECHDC3 mRNA | CTD | PMID:28903501 | Echdc3 | Rat | quercetin | affects expression | EXP | | 6480464 | Quercetin affects the expression of ECHDC3 mRNA | CTD | PMID:18178720 | Echdc3 | Rat | rotenone | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of ECHDC3 protein | CTD | PMID:39603559 | Echdc3 | Rat | SB 431542 | multiple interactions | ISO | ECHDC3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Echdc3 | Rat | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of ECHDC3 protein | CTD | PMID:29459688 | Echdc3 | Rat | sodium arsenite | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ECHDC3 mRNA | CTD | PMID:38568856 | Echdc3 | Rat | tamoxifen | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Tamoxifen results in decreased expression of ECHDC3 mRNA | CTD | PMID:25123088 | Echdc3 | Rat | tamoxifen | affects expression | ISO | Echdc3 (Mus musculus) | 6480464 | Tamoxifen affects the expression of ECHDC3 mRNA | CTD | PMID:17555576 | Echdc3 | Rat | tanespimycin | multiple interactions | ISO | ECHDC3 (Homo sapiens) | 6480464 | [tanespimycin co-treated with VER 155008] results in decreased expression of ECHDC3 protein | CTD | PMID:31370342 | Echdc3 | Rat | terbufos | increases methylation | ISO | ECHDC3 (Homo sapiens) | 6480464 | terbufos results in increased methylation of ECHDC3 promoter | CTD | PMID:22847954 | Echdc3 | Rat | testosterone | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Testosterone results in decreased expression of ECHDC3 mRNA | CTD | PMID:21669218 | Echdc3 | Rat | tetrachloromethane | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of ECHDC3 mRNA | CTD | PMID:17484886|PMID:27339419|PMID:31919559 | Echdc3 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ECHDC3 mRNA | CTD | PMID:31150632 | Echdc3 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ECHDC3 mRNA] | CTD | PMID:31150632 | Echdc3 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of ECHDC3 mRNA | CTD | PMID:23411599|PMID:34492290 | Echdc3 | Rat | thiram | decreases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Thiram results in decreased expression of ECHDC3 mRNA | CTD | PMID:38568856 | Echdc3 | Rat | titanium dioxide | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ECHDC3 mRNA | CTD | PMID:23557971 | Echdc3 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ECHDC3 mRNA | CTD | PMID:33387578 | Echdc3 | Rat | trichostatin A | increases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ECHDC3 mRNA | CTD | PMID:24935251 | Echdc3 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of ECHDC3 mRNA | CTD | PMID:30589522 | Echdc3 | Rat | triphenyl phosphate | affects expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ECHDC3 mRNA | CTD | PMID:37042841 | Echdc3 | Rat | triptonide | increases expression | ISO | Echdc3 (Mus musculus) | 6480464 | triptonide results in increased expression of ECHDC3 mRNA | CTD | PMID:33045310 | Echdc3 | Rat | trovafloxacin | decreases expression | ISO | Echdc3 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of ECHDC3 mRNA | CTD | PMID:35537566 | Echdc3 | Rat | valproic acid | affects expression | ISO | Echdc3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ECHDC3 mRNA | CTD | PMID:17292431 | Echdc3 | Rat | valproic acid | increases expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ECHDC3 mRNA | CTD | PMID:23179753|PMID:24935251 | Echdc3 | Rat | valproic acid | affects expression | ISO | ECHDC3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ECHDC3 mRNA | CTD | PMID:25979313 | Echdc3 | Rat | vancomycin | increases expression | ISO | Echdc3 (Mus musculus) | 6480464 | Vancomycin results in increased expression of ECHDC3 mRNA | CTD | PMID:18930951 | | |||||||||||||||||||||||||||||||||||||||






















