Meis1 (Meis homeobox 1) - Rat Genome Database

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Gene: Meis1 (Meis homeobox 1) Rattus norvegicus
Analyze
Symbol: Meis1
Name: Meis homeobox 1
RGD ID: 1585482
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in cell growth involved in cardiac muscle cell development. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Orthologous to human MEIS1 (Meis homeobox 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: homeobox protein Meis1; LOC108352805; LOC686117; Meis1, myeloid ecotropic viral integration site 1 homolog; similar to myeloid ecotropic viral integration site 1; uncharacterized LOC108352805
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81497,356,949 - 97,499,646 (-)NCBIGRCr8
mRatBN7.21493,155,426 - 93,294,373 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1493,155,419 - 93,294,265 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1497,471,782 - 97,610,378 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01498,716,059 - 98,854,667 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01495,181,092 - 95,319,673 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014103,182,178 - 103,321,809 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14103,181,281 - 103,321,270 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014102,927,220 - 103,064,633 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41499,693,567 - 99,832,273 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1492,182,045 - 92,319,516 (-)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Meis1RatCardiomegaly  ISOMeis1 (Mus musculus)11554891mRNA and protein:decreased expression:heart (mouse)RGD 
Meis1Ratheart disease  ISOMEIS1 (Homo sapiens)11554891mRNA and protein:decreased expression:heart (human)RGD 
Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Meis1RatBreast Neoplasms  ISOMEIS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19776672
Meis1Ratrestless legs syndrome  ISOMEIS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17637780 and PMID:28604731
Meis1RatSleep Initiation and Maintenance Disorders  ISOMEIS1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28604731
Object Symbol
Species
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Original Reference(s)
Meis1Ratrestless legs syndrome  ISSMeis1 (Mus musculus)13592920 MouseDO 

1 to 20 of 117 rows

  
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Original Reference(s)
Meis1Rat(R)-adrenaline decreases expressionISOMeis1 (Mus musculus)6480464Epinephrine results in decreased expression of MEIS1 proteinCTDPMID:31520687
Meis1Rat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in decreased expression of MEIS1 mRNACTDPMID:26496021
Meis1Rat17beta-estradiol increases expressionISOMEIS1 (Homo sapiens)6480464Estradiol results in increased expression of MEIS1 mRNACTDPMID:31614463
Meis1Rat17beta-hydroxy-5alpha-androstan-3-one increases expressionISOMEIS1 (Homo sapiens)6480464Dihydrotestosterone results in increased expression of MEIS1 mRNACTDPMID:29581250
Meis1Rat2,2',4,4',5,5'-hexachlorobiphenyl decreases expressionISOMEIS1 (Homo sapiens)64804642 more ...CTDPMID:23146750
Meis1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOMeis1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of MEIS1 mRNACTDPMID:24058054
Meis1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of MEIS1 mRNACTDPMID:34747641
Meis1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMeis1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of MEIS1 mRNACTDPMID:21570461
Meis1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MEIS1 mRNACTDPMID:21215274 more ...
Meis1Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Meis1Rat2-hydroxypropanoic acid increases expressionISOMEIS1 (Homo sapiens)6480464Lactic Acid results in increased expression of MEIS1 mRNACTDPMID:30851411
Meis1Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOMEIS1 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MEIS1 mRNACTDPMID:28628672
Meis1Rat4,4'-sulfonyldiphenol decreases methylationISOMEIS1 (Homo sapiens)6480464bisphenol S results in decreased methylation of MEIS1 geneCTDPMID:31601247
Meis1Rat4-hydroxyphenyl retinamide decreases expressionISOMeis1 (Mus musculus)6480464Fenretinide results in decreased expression of MEIS1 mRNACTDPMID:28973697
Meis1Rat4-hydroxyphenyl retinamide increases expressionISOMeis1 (Mus musculus)6480464Fenretinide results in increased expression of MEIS1 mRNACTDPMID:28973697
Meis1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of MEIS1 mRNACTDPMID:24780913
Meis1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of MEIS1 mRNACTDPMID:30047161
Meis1Rat9-cis-retinoic acid increases expressionISOMEIS1 (Homo sapiens)6480464Alitretinoin results in increased expression of MEIS1 mRNACTDPMID:17034753
Meis1Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of MEIS1 mRNACTDPMID:28959563
Meis1Ratacrylamide decreases expressionISOMEIS1 (Homo sapiens)6480464Acrylamide results in decreased expression of MEIS1 mRNACTDPMID:32763439

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Biological Process
1 to 20 of 32 rows

  
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Original Reference(s)
Meis1Ratangiogenesis involved_inIBAMGI:104717 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Meis1Ratangiogenesis acts_upstream_of_or_withinIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1Ratangiogenesis acts_upstream_of_or_withinISOMeis1 (Mus musculus)1624291MGI:3029063 PMID:14713950RGDPMID:14713950
Meis1Ratanimal organ morphogenesis involved_inIBAFB:FBgn0001235 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Meis1Ratblood vessel morphogenesis acts_upstream_of_or_withinISOMeis1 (Mus musculus)1624291MGI:3578637 PMID:15882575RGDPMID:15882575
Meis1Ratblood vessel morphogenesis acts_upstream_of_or_withinIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1Ratbrain development involved_inIBAFB:FBgn0001235 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Meis1Ratcell growth involved in cardiac muscle cell development  IMP 11554891 RGD 
Meis1Ratdefinitive hemopoiesis acts_upstream_of_or_withinISOMeis1 (Mus musculus)1624291MGI:3578637 PMID:15882575RGDPMID:15882575
Meis1Ratdefinitive hemopoiesis acts_upstream_of_or_withinIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1Ratembryonic pattern specification involved_inIBAFB:FBgn0001235 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Meis1Rateye development involved_inIBAFB:FBgn0001235 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Meis1Rathemopoiesis acts_upstream_of_or_withinISOMeis1 (Mus musculus)1624291MGI:3029063 PMID:14713950RGDPMID:14713950
Meis1Rathemopoiesis acts_upstream_of_or_withinIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1Rathemopoiesis involved_inIBAMGI:104717 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Meis1Ratlens morphogenesis in camera-type eye acts_upstream_of_or_withinISOMeis1 (Mus musculus)1624291MGI:3029063 PMID:14713950RGDPMID:14713950
Meis1Ratlens morphogenesis in camera-type eye acts_upstream_of_or_withinIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1Ratlocomotory behavior acts_upstream_of_or_withinIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1Ratlocomotory behavior acts_upstream_of_or_withinISOMeis1 (Mus musculus)1624291MGI:3578637 PMID:24642863RGDPMID:24642863
Meis1Ratmegakaryocyte development acts_upstream_of_or_withinISOMeis1 (Mus musculus)1624291MGI:3578637 PMID:20203303RGDPMID:20203303
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Cellular Component

  
Object Symbol
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Original Reference(s)
Meis1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Meis1Ratnucleus located_inISOMeis1 (Mus musculus)1624291 PMID:10842069 more ...RGDPMID:10842069 more ...
Meis1Ratnucleus located_inIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1Ratnucleus located_inIEAUniRule:UR0004010371600115GO_REF:0000104UniProtGO_REF:0000104
Meis1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Meis1Rattranscription regulator complex part_ofIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1Rattranscription regulator complex part_ofISOMeis1 (Mus musculus)1624291 PMID:10373562 more ...RGDPMID:10373562 more ...

Molecular Function
1 to 20 of 23 rows

  
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Original Reference(s)
Meis1Ratchromatin binding enablesISOMeis1 (Mus musculus)1624291 PMID:19268698RGDPMID:19268698
Meis1Ratchromatin binding enablesIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1RatDNA binding enablesISOMEIS1 (Homo sapiens)1624291 PMID:26550823RGDPMID:26550823
Meis1RatDNA binding enablesIEAUniProtKB-KW:KW-03711600115GO_REF:0000043UniProtGO_REF:0000043
Meis1RatDNA binding enablesISOMeis1 (Mus musculus)1624291 PMID:9343407RGDPMID:9343407
Meis1RatDNA binding enablesIEAUniProtKB-KW:KW-0238 and UniProtKB-KW:KW-03711600115GO_REF:0000043UniProtGO_REF:0000043
Meis1RatDNA binding enablesIEAUniRule:UR0004010371600115GO_REF:0000104UniProtGO_REF:0000104
Meis1RatDNA binding enablesIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1RatDNA binding enablesIEAInterPro:IPR001356 and InterPro:IPR0084221600115GO_REF:0000002InterProGO_REF:0000002
Meis1RatDNA binding enablesIEAUniProtKB:O00470 and ensembl:ENSP000002723691600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesIBAMGI:104717 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Meis1RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOMeis1 (Mus musculus)1624291 PMID:19799567RGDPMID:19799567
Meis1RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIEAUniProtKB:Q60954 and ensembl:ENSMUSP000001392191600115GO_REF:0000107EnsemblGO_REF:0000107
Meis1RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesISOMeis1 (Mus musculus)1624291 PMID:10373562RGDPMID:10373562
Meis1RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIEAARBA:ARBA000290161600115GO_REF:0000117UniProtGO_REF:0000117
Meis1Ratprotein binding enablesISOMEIS1 (Homo sapiens)1624291UniProtKB:P14921 more ...RGDPMID:18692240 more ...
Meis1Ratprotein binding enablesISOMeis1 (Mus musculus)1624291PR:O70477 more ...RGDPMID:10373562 more ...
Meis1Ratprotein binding enablesISOMeis1 (Mus musculus) and PR:Q60954-21624291UniProtKB:Q62424 and PMID:15617687RGDPMID:15617687
Meis1RatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISOMeis1 (Mus musculus)1624291 PMID:12183364 more ...RGDPMID:12183364 more ...
1 to 20 of 23 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Effect of changes in food consistency on NADH-ubiquinone oxidoreductase activity and levels of mRNA for ND1, 51kDa, 75kDa and myosin heavy chain isoforms in two different portions of rat masseter muscle. Ide Y and Sato I, Okajimas Folia Anat Jpn. 2006 Aug;83(2):61-71.
3. MicroRNAs regulating meis1 expression and inducing cardiomyocyte proliferation. Pandey R, etal., Cardiovasc Regen Med. 2016;3. pii: e1468.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Meis1 promotes poly (rC)-binding protein 2 expression and inhibits angiotensin II-induced cardiomyocyte hypertrophy. Zhang Y, etal., IUBMB Life. 2016 Jan;68(1):13-22. doi: 10.1002/iub.1456. Epub 2015 Nov 24.
PMID:9315626   PMID:9343407   PMID:9405651   PMID:10373562   PMID:10842069   PMID:11438208   PMID:12183364   PMID:12477932   PMID:14713950   PMID:15465489   PMID:15617687   PMID:15634706  
PMID:15882575   PMID:17049510   PMID:17056599   PMID:17178831   PMID:18164701   PMID:19268698   PMID:19799567   PMID:20203303   PMID:21059917   PMID:24642863   PMID:26550823   PMID:32450174  



Meis1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81497,356,949 - 97,499,646 (-)NCBIGRCr8
mRatBN7.21493,155,426 - 93,294,373 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1493,155,419 - 93,294,265 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1497,471,782 - 97,610,378 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01498,716,059 - 98,854,667 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01495,181,092 - 95,319,673 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014103,182,178 - 103,321,809 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14103,181,281 - 103,321,270 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014102,927,220 - 103,064,633 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41499,693,567 - 99,832,273 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1492,182,045 - 92,319,516 (-)NCBICelera
Cytogenetic Map14q22NCBI
MEIS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38266,435,125 - 66,573,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl266,433,452 - 66,573,869 (+)EnsemblGRCh38hg38GRCh38
GRCh37266,662,257 - 66,801,001 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36266,516,036 - 66,653,395 (+)NCBINCBI36Build 36hg18NCBI36
Build 34266,574,182 - 66,711,541NCBI
Celera266,510,942 - 66,648,316 (+)NCBICelera
Cytogenetic Map2p14NCBI
HuRef266,397,888 - 66,535,182 (+)NCBIHuRef
CHM1_1266,593,726 - 66,731,071 (+)NCBICHM1_1
T2T-CHM13v2.0266,444,205 - 66,582,943 (+)NCBIT2T-CHM13v2.0
Meis1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391118,830,428 - 18,968,992 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1118,829,817 - 18,968,985 (-)EnsemblGRCm39 Ensembl
GRCm381118,880,428 - 19,019,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1118,879,817 - 19,018,985 (-)EnsemblGRCm38mm10GRCm38
MGSCv371118,780,431 - 18,918,683 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361118,780,431 - 18,918,683 (-)NCBIMGSCv36mm8
Celera1121,034,144 - 21,171,771 (-)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1111.11NCBI
Meis1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542418,058,004 - 18,190,453 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542418,060,499 - 18,190,425 (-)NCBIChiLan1.0ChiLan1.0
MEIS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21259,830,340 - 59,968,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A59,833,083 - 59,972,676 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A66,494,934 - 66,633,295 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A67,615,941 - 67,752,958 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A67,615,941 - 67,752,958 (+)Ensemblpanpan1.1panPan2
MEIS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11065,765,498 - 65,898,714 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1065,683,560 - 65,897,573 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1065,654,860 - 65,820,227 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01066,778,156 - 66,943,912 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1066,778,687 - 66,927,290 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11066,456,570 - 66,622,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01066,764,024 - 66,929,260 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01067,059,265 - 67,224,762 (+)NCBIUU_Cfam_GSD_1.0
Meis1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629217,354,842 - 17,491,236 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649111,079,455 - 11,217,388 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649111,079,574 - 11,216,451 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEIS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl375,485,022 - 75,625,040 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1375,485,024 - 75,625,855 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2379,331,016 - 79,362,238 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MEIS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11440,473,148 - 40,613,245 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1440,471,063 - 40,611,071 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604571,303,335 - 71,444,475 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Meis1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247626,873,913 - 7,031,346 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247626,894,332 - 7,031,354 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Meis1
821 total Variants

Predicted Target Of
Summary Value
Count of predictions:405
Count of miRNA genes:229
Interacting mature miRNAs:281
Transcripts:ENSRNOT00000006157
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582201Sffal2Serum free fatty acids level QTL 240.0002blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)149255388695876975Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat

1 to 10 of 15 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000006157   ⟹   ENSRNOP00000006157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1493,155,435 - 93,291,701 (-)Ensembl
Rnor_6.0 Ensembl14103,181,281 - 103,321,270 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098187   ⟹   ENSRNOP00000083074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1493,178,917 - 93,293,720 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104415   ⟹   ENSRNOP00000089570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1493,155,435 - 93,294,260 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107521   ⟹   ENSRNOP00000097699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1493,155,419 - 93,294,265 (-)Ensembl
RefSeq Acc Id: NM_001134702   ⟹   NP_001128174
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,495,083 (-)NCBI
mRatBN7.21493,155,433 - 93,293,595 (-)NCBI
Rnor_6.014103,182,178 - 103,321,129 (-)NCBI
Rnor_5.014102,927,220 - 103,064,633 (-)NCBI
RGSC_v3.41499,693,567 - 99,832,273 (-)RGD
Celera1492,182,045 - 92,319,516 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251529   ⟹   XP_006251591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,497,391 (-)NCBI
mRatBN7.21493,155,426 - 93,294,373 (-)NCBI
Rnor_6.014103,182,178 - 103,321,809 (-)NCBI
Rnor_5.014102,927,220 - 103,064,633 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092454   ⟹   XP_038948382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,360,334 - 97,497,391 (-)NCBI
mRatBN7.21493,155,426 - 93,294,373 (-)NCBI
RefSeq Acc Id: XM_039092455   ⟹   XP_038948383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,487,583 (-)NCBI
mRatBN7.21493,155,426 - 93,286,102 (-)NCBI
RefSeq Acc Id: XM_063273628   ⟹   XP_063129698
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,497,391 (-)NCBI
RefSeq Acc Id: XM_063273629   ⟹   XP_063129699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,356,949 - 97,499,646 (-)NCBI
RefSeq Acc Id: XM_063273630   ⟹   XP_063129700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,360,334 - 97,497,391 (-)NCBI
RefSeq Acc Id: XR_005493013
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81497,360,738 - 97,497,391 (-)NCBI
mRatBN7.21493,159,227 - 93,294,373 (-)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: NP_001128174   ⟸   NM_001134702
- UniProtKB: B1WC31 (UniProtKB/TrEMBL),   F7EL40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251591   ⟸   XM_006251529
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GMM6 (UniProtKB/TrEMBL),   A6JQ06 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006157   ⟸   ENSRNOT00000006157
RefSeq Acc Id: XP_038948382   ⟸   XM_039092454
- Peptide Label: isoform X4
- UniProtKB: B1WC31 (UniProtKB/TrEMBL),   F7EL40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948383   ⟸   XM_039092455
- Peptide Label: isoform X6
Homeobox   KN homeodomain   MEIS N-terminal

Name Modeler Protein Id AA Range Protein Structure
AF-B1WC31-F1-model_v2 AlphaFold B1WC31 1-390 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699506
Promoter ID:EPDNEW_R10030
Type:initiation region
Name:Meis1_1
Description:Meis homeobox 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014103,321,293 - 103,321,353EPDNEW


1 to 32 of 32 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14914 BioCyc
Ensembl Genes ENSRNOG00000004606 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006157 ENTREZGENE
  ENSRNOT00000006157.6 UniProtKB/TrEMBL
  ENSRNOT00000098187.1 UniProtKB/TrEMBL
  ENSRNOT00000104415 ENTREZGENE
  ENSRNOT00000104415.1 UniProtKB/TrEMBL
  ENSRNOT00000107521.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9030600 IMAGE-MGC_LOAD
InterPro Homeobox UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  PKNOX/Meis_N UniProtKB/TrEMBL
  TALE_homeobox UniProtKB/TrEMBL
KEGG Report rno:686117 UniProtKB/TrEMBL
MGC_CLONE MGC:187802 IMAGE-MGC_LOAD
NCBI Gene 686117 ENTREZGENE
PANTHER HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  Meis_PKNOX_N UniProtKB/TrEMBL
PhenoGen Meis1 PhenoGen
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004606 RatGTEx
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A0A8I5ZVB5_RAT UniProtKB/TrEMBL
  A0A8I6GI80_RAT UniProtKB/TrEMBL
  A0A8I6GMM6 ENTREZGENE, UniProtKB/TrEMBL
  A6JQ06 ENTREZGENE, UniProtKB/TrEMBL
  B1WC31 ENTREZGENE, UniProtKB/TrEMBL
  F7EL40 ENTREZGENE, UniProtKB/TrEMBL
1 to 32 of 32 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Meis1  Meis homeobox 1  LOC108352805  uncharacterized LOC108352805  Data merged from RGD:11361306 737654 PROVISIONAL
2016-08-02 LOC108352805  uncharacterized LOC108352805      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-18 Meis1  Meis homeobox 1   LOC686117  similar to myeloid ecotropic viral integration site 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC686117  similar to myeloid ecotropic viral integration site 1  LOC679409  similar to Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1)  Data merged from RGD:1588354 1643240 APPROVED
2006-11-19 LOC686117  similar to myeloid ecotropic viral integration site 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC679409  similar to Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1)      Symbol and Name status set to provisional 70820 PROVISIONAL