Hoxa11 (homeobox A11) - Rat Genome Database

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Pathways
Gene: Hoxa11 (homeobox A11) Rattus norvegicus
Analyze
Symbol: Hoxa11
Name: homeobox A11
RGD ID: 1564605
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in prostate gland development; response to estrogen; and response to testosterone. Predicted to be located in nucleoplasm. Predicted to be part of protein-DNA complex and transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in radioulnar synostosis. Orthologous to human HOXA11 (homeobox A11); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: homeo box A10; homeobox protein A10; homeobox protein Hox-A11; homeobox protein Hox-A11-like; Hoxa10; LOC100909443; LOC368057; LOC500127; MGC188427; RGD1564605; RGD1566402; similar to homeobox protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,673,139 - 82,676,801 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl482,673,140 - 82,676,844 (-)EnsemblGRCr8
mRatBN7.2481,342,527 - 81,346,189 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,342,528 - 81,346,232 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx486,564,339 - 86,567,995 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0482,339,730 - 82,343,386 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,766,832 - 80,770,490 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0482,296,888 - 82,301,419 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,211,366 - 82,215,022 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl482,298,152 - 82,300,503 (-)Ensemblrn6Rnor6.0
Rnor_5.04146,963,720 - 146,967,382 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4480,542,417 - 80,546,079NCBIRGSC_v3.4RGSC_v3.4rn4
Celera476,233,120 - 76,236,782 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes. Huang L, etal., Endocrinology. 2007 Mar;148(3):1235-45. Epub 2006 Nov 30.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Abnormalities of vertebral formation and Hox expression in congenital kyphoscoliotic rats. Seki T, etal., Mol Cell Biochem. 2008 May;312(1-2):193-9. doi: 10.1007/s11010-008-9734-4. Epub 2008 Mar 9.
8. Amegakaryocytic thrombocytopenia and radio-ulnar synostosis are associated with HOXA11 mutation. Thompson AA and Nguyen LT, Nat Genet. 2000 Dec;26(4):397-8.
9. Developmental exposure to Bisphenol a impairs the uterine response to ovarian steroids in the adult. Varayoud J, etal., Endocrinology. 2008 Nov;149(11):5848-60. doi: 10.1210/en.2008-0651. Epub 2008 Jul 24.
Additional References at PubMed
PMID:7596412   PMID:7702549   PMID:7789268   PMID:9343407   PMID:11493536   PMID:11900456   PMID:12050119   PMID:12477932   PMID:12869760   PMID:14668414   PMID:15057822   PMID:15632090  
PMID:17785448   PMID:18249394   PMID:18701816   PMID:20978074   PMID:22916278   PMID:23760953  


Genomics

Comparative Map Data
Hoxa11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,673,139 - 82,676,801 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl482,673,140 - 82,676,844 (-)EnsemblGRCr8
mRatBN7.2481,342,527 - 81,346,189 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,342,528 - 81,346,232 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx486,564,339 - 86,567,995 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0482,339,730 - 82,343,386 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,766,832 - 80,770,490 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0482,296,888 - 82,301,419 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,211,366 - 82,215,022 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl482,298,152 - 82,300,503 (-)Ensemblrn6Rnor6.0
Rnor_5.04146,963,720 - 146,967,382 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4480,542,417 - 80,546,079NCBIRGSC_v3.4RGSC_v3.4rn4
Celera476,233,120 - 76,236,782 (-)NCBICelera
Cytogenetic Map4q24NCBI
HOXA11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38727,181,157 - 27,185,232 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl727,181,157 - 27,185,232 (-)Ensemblhg38GRCh38
GRCh37727,220,776 - 27,224,851 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36727,187,301 - 27,191,360 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34726,994,368 - 26,998,070NCBI
Celera727,209,715 - 27,213,774 (-)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef727,101,338 - 27,105,401 (-)NCBIHuRef
CHM1_1727,220,497 - 27,224,560 (-)NCBICHM1_1
T2T-CHM13v2.0727,317,166 - 27,321,240 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2727,271,961 - 27,276,020 (-)NCBI
Hoxa11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,219,086 - 52,222,784 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,219,086 - 52,222,790 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38652,242,105 - 52,245,810 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,242,106 - 52,245,810 (-)Ensemblmm10GRCm38
MGSCv37652,192,105 - 52,195,766 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36652,171,689 - 52,175,350 (-)NCBIMGSCv36mm8
Celera652,763,744 - 52,767,403 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.4NCBI
Hoxa11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541028,877,055 - 28,879,465 (-)Ensembl
ChiLan1.0NW_00495541028,875,780 - 28,879,643 (-)NCBIChiLan1.0ChiLan1.0
HOXA11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2632,010,718 - 32,018,056 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1780,335,092 - 80,339,154 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0727,826,003 - 27,829,757 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1727,426,602 - 27,429,092 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl727,424,759 - 27,429,103 (-)EnsemblpanPan2panpan1.1
HOXA11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,355,907 - 40,360,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,357,478 - 40,359,919 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1439,786,761 - 39,790,944 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01440,294,564 - 40,298,764 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,295,087 - 40,299,055 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,408,521 - 40,412,708 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,093,599 - 40,097,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,452,219 - 40,456,401 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hoxa11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,597,557 - 84,601,354 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,809,288 - 3,813,014 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,809,288 - 3,813,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXA11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1845,388,375 - 45,391,953 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11845,388,523 - 45,392,190 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,021,709 - 50,025,376 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOXA11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,180,232 - 31,187,709 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,183,682 - 31,186,010 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604273,546,525 - 73,553,107 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxa11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247393,418,723 - 3,423,950 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247393,420,501 - 3,424,151 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Hoxa11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1688,816,578 - 88,820,420 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hoxa11
25 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1182
Count of miRNA genes:291
Interacting mature miRNAs:371
Transcripts:ENSRNOT00000010256, ENSRNOT00000071568
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)480212111119233320Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)471647492116647492Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)48021363484338055Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)480216705104243248Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)469036742114036742Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)468353567113353567Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)46104105794638356Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46390045888813920Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat

Markers in Region
U20371  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,343,516 - 81,343,709 (+)MAPPERmRatBN7.2
Rnor_6.0482,297,879 - 82,298,071NCBIRnor6.0
Rnor_6.0482,212,355 - 82,212,547NCBIRnor6.0
Rnor_5.04146,879,186 - 146,879,378UniSTSRnor5.0
Rnor_5.04146,964,710 - 146,964,902UniSTSRnor5.0
RGSC_v3.4480,543,407 - 80,543,599UniSTSRGSC3.4
Celera476,234,110 - 76,234,302UniSTS
Cytogenetic Map4q24UniSTS
D7S2774  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,332,478 - 81,332,819 (+)MAPPERmRatBN7.2
Rnor_6.0482,286,842 - 82,287,182NCBIRnor6.0
Rnor_6.0482,201,047 - 82,201,387NCBIRnor6.0
Rnor_5.04146,867,878 - 146,868,218UniSTSRnor5.0
Rnor_5.04146,953,673 - 146,954,013UniSTSRnor5.0
RGSC_v3.4480,532,370 - 80,532,710UniSTSRGSC3.4
Celera476,223,112 - 76,223,452UniSTS
Cytogenetic Map4q24UniSTS
AA893141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,332,690 - 81,332,897 (+)MAPPERmRatBN7.2
Rnor_6.0482,287,054 - 82,287,260NCBIRnor6.0
Rnor_6.0482,201,259 - 82,201,465NCBIRnor6.0
Rnor_5.04146,953,885 - 146,954,091UniSTSRnor5.0
Rnor_5.04146,868,090 - 146,868,296UniSTSRnor5.0
RGSC_v3.4480,532,582 - 80,532,788UniSTSRGSC3.4
Celera476,223,324 - 76,223,530UniSTS
RH 3.4 Map4513.31UniSTS
Cytogenetic Map4q24UniSTS
UniSTS:498386  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,343,486 - 81,343,571 (+)MAPPERmRatBN7.2
Rnor_6.0482,297,849 - 82,297,933NCBIRnor6.0
Rnor_6.0482,212,325 - 82,212,409NCBIRnor6.0
Rnor_5.04146,879,156 - 146,879,240UniSTSRnor5.0
Rnor_5.04146,964,680 - 146,964,764UniSTSRnor5.0
RGSC_v3.4480,543,377 - 80,543,461UniSTSRGSC3.4
Celera476,234,080 - 76,234,164UniSTS
Cytogenetic Map4q24UniSTS
UniSTS:474751  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,342,863 - 81,343,174 (+)MAPPERmRatBN7.2
Rnor_6.0482,297,226 - 82,297,536NCBIRnor6.0
Rnor_6.0482,211,702 - 82,212,012NCBIRnor6.0
Rnor_5.04146,878,533 - 146,878,843UniSTSRnor5.0
Rnor_5.04146,964,057 - 146,964,367UniSTSRnor5.0
RGSC_v3.4480,542,754 - 80,543,064UniSTSRGSC3.4
Celera476,233,457 - 76,233,767UniSTS
Cytogenetic Map4q24UniSTS
REN100703  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,248 - 81,345,474 (+)MAPPERmRatBN7.2
Rnor_6.0482,299,611 - 82,299,836NCBIRnor6.0
Rnor_6.0482,214,087 - 82,214,312NCBIRnor6.0
Rnor_5.04146,880,918 - 146,881,143UniSTSRnor5.0
Rnor_5.04146,966,442 - 146,966,667UniSTSRnor5.0
RGSC_v3.4480,545,139 - 80,545,364UniSTSRGSC3.4
Celera476,235,842 - 76,236,067UniSTS
Cytogenetic Map4q24UniSTS
REN100704  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,451 - 81,345,682 (+)MAPPERmRatBN7.2
Rnor_6.0482,299,814 - 82,300,044NCBIRnor6.0
Rnor_6.0482,214,290 - 82,214,520NCBIRnor6.0
Rnor_5.04146,881,121 - 146,881,351UniSTSRnor5.0
Rnor_5.04146,966,645 - 146,966,875UniSTSRnor5.0
RGSC_v3.4480,545,342 - 80,545,572UniSTSRGSC3.4
Celera476,236,045 - 76,236,275UniSTS
Cytogenetic Map4q24UniSTS
REN100706  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,887 - 81,346,147 (+)MAPPERmRatBN7.2
Rnor_6.0482,300,250 - 82,300,509NCBIRnor6.0
Rnor_6.0482,214,726 - 82,214,985NCBIRnor6.0
Rnor_5.04146,881,557 - 146,881,816UniSTSRnor5.0
Rnor_5.04146,967,081 - 146,967,340UniSTSRnor5.0
RGSC_v3.4480,545,778 - 80,546,037UniSTSRGSC3.4
Celera476,236,481 - 76,236,740UniSTS
Cytogenetic Map4q24UniSTS
ECD05496  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,709 - 81,346,446 (+)MAPPERmRatBN7.2
Rnor_6.0482,300,072 - 82,300,808NCBIRnor6.0
Rnor_6.0482,214,548 - 82,215,284NCBIRnor6.0
Rnor_5.04146,881,379 - 146,882,115UniSTSRnor5.0
Rnor_5.04146,966,903 - 146,967,639UniSTSRnor5.0
RGSC_v3.4480,545,600 - 80,546,336UniSTSRGSC3.4
Celera476,236,303 - 76,237,039UniSTS
Cytogenetic Map4q24UniSTS
Hoxa11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,990 - 81,346,064 (+)MAPPERmRatBN7.2
Rnor_6.0482,214,829 - 82,214,902NCBIRnor6.0
Rnor_6.0482,300,353 - 82,300,426NCBIRnor6.0
Rnor_5.04146,967,184 - 146,967,257UniSTSRnor5.0
Rnor_5.04146,881,660 - 146,881,733UniSTSRnor5.0
Celera476,236,584 - 76,236,657UniSTS
Cytogenetic Map4q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
21 11 12 58 60 53 28 14 28 12 219 63 10 26 100 91 25

Sequence


Ensembl Acc Id: ENSRNOT00000010256   ⟹   ENSRNOP00000010256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl482,673,140 - 82,676,844 (-)Ensembl
mRatBN7.2 Ensembl481,342,528 - 81,346,232 (-)Ensembl
Rnor_6.0 Ensembl482,211,366 - 82,215,022 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000071568   ⟹   ENSRNOP00000066085
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl482,298,152 - 82,300,503 (-)Ensembl
RefSeq Acc Id: NM_001129878   ⟹   NP_001123350
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8482,673,139 - 82,676,801 (-)NCBI
mRatBN7.2481,342,527 - 81,346,189 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001123350 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66717 (Get FASTA)   NCBI Sequence Viewer  
  AAP31870 (Get FASTA)   NCBI Sequence Viewer  
  EDL88153 (Get FASTA)   NCBI Sequence Viewer  
  EDL88154 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010256
  ENSRNOP00000010256.3
Ensembl Acc Id: ENSRNOP00000010256   ⟸   ENSRNOT00000010256
Ensembl Acc Id: ENSRNOP00000066085   ⟸   ENSRNOT00000071568
RefSeq Acc Id: NP_001123350   ⟸   NM_001129878
- UniProtKB: A6K0R5 (UniProtKB/TrEMBL),   B2RYB5 (UniProtKB/TrEMBL),   G3V6Z0 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Homeobox

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V6Z0-F1-model_v2 AlphaFold G3V6Z0 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693059
Promoter ID:EPDNEW_R3580
Type:initiation region
Name:Hoxa11_1
Description:homeobox A11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0482,300,586 - 82,300,646EPDNEW
RGD ID:13693061
Promoter ID:EPDNEW_R3581
Type:single initiation site
Name:AABR07060585_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0482,300,786 - 82,300,846EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564605 AgrOrtholog
BioCyc Gene G2FUF-44811 BioCyc
Ensembl Genes ENSRNOG00000053884 Ensembl
  ENSRNOG00000059870 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010256 ENTREZGENE
  ENSRNOT00000010256.7 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro DUF3528 UniProtKB/TrEMBL
  Homeobox UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_eu UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
KEGG Report rno:103692131 UniProtKB/TrEMBL
NCBI Gene Hoxa11 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX-A11 UniProtKB/TrEMBL
  HOMEOBOX PROTEIN HOX-A11-RELATED UniProtKB/TrEMBL
Pfam DUF3528 UniProtKB/TrEMBL
  Homeobox UniProtKB/TrEMBL
PhenoGen Hoxa11 PhenoGen
PRINTS HOMEOBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053884 RatGTEx
  ENSRNOG00000059870 RatGTEx
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A6K0R5 ENTREZGENE, UniProtKB/TrEMBL
  B2RYB5 ENTREZGENE, UniProtKB/TrEMBL
  G3V6Z0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Hoxa11  homeobox A11  LOC100909443  homeobox protein Hox-A11-like  Data merged from RGD:6503602 737654 PROVISIONAL
2013-05-24 Hoxa11  homeobox A11  RGD1566402  similar to homeobox protein  Data merged from RGD:1566402 1643240 APPROVED
2012-07-17 Hoxa11  homeobox A11  Hoxa10  homeo box A10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100909443  homeobox protein Hox-A11-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100911743  homeobox protein Hox-A11-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1566402  similar to homeobox protein   RGD1566402_predicted  similar to homeobox protein (predicted)  'predicted' is removed 2292626 APPROVED
2008-03-06 Hoxa10  homeo box A10  RGD1564605_predicted  similar to Homeobox protein A10 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564605_predicted  similar to Homeobox protein A10 (predicted)  LOC368057  similar to Homeobox protein A10  Symbol and Name status set to approved 1299863 APPROVED
2006-03-07 RGD1566402_predicted  similar to homeobox protein (predicted)  LOC500127  similar to homeobox protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC368057  similar to Homeobox protein A10      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 LOC500127  similar to homeobox protein      Symbol and Name status set to provisional 70820 PROVISIONAL