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| # | Reference Title | Reference Citation |
| 1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | Cloning of rat MLH1 and expression analysis of MSH2, MSH3, MSH6, and MLH1 during spermatogenesis. | Geeta Vani R, etal., Genomics 1999 Dec 15;62(3):460-7. |
| 3. | Mechanisms and functions of DNA mismatch repair. | Li GM Cell Res. 2008 Jan;18(1):85-98. |
| 4. | Association between DNA mismatch repair gene polymorphisms and platinum-based chemotherapy toxicity in non-small cell lung cancer patients. | Liu JY, etal., Chin J Cancer. 2017 Jan 16;36(1):12. doi: 10.1186/s40880-016-0175-2. |
| 5. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
| 6. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 7. | GOA pipeline | RGD automated data pipeline |
| 8. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 9. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 10. | Comprehensive gene review and curation | RGD comprehensive gene curation |
| 11. | Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair. | Risinger JI, etal., Nat Genet. 1996 Sep;14(1):102-5. |
| 12. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| 13. | Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas. | Yin J, etal., Hum Mutat. 1997;10(6):474-8. |
| PMID:8942985 | PMID:10545954 | PMID:10662804 | PMID:10706084 | PMID:11427529 | PMID:11691815 | PMID:11756455 | PMID:11809883 | PMID:15238604 | PMID:16260499 | PMID:16388310 | PMID:16728433 |
| PMID:17715146 | PMID:19946888 | PMID:26300262 |
| Msh3 (Rattus norvegicus - Norway rat) |
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| MSH3 (Homo sapiens - human) |
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| Msh3 (Mus musculus - house mouse) |
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| Msh3 (Chinchilla lanigera - long-tailed chinchilla) |
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| MSH3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| MSH3 (Canis lupus familiaris - dog) |
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| Msh3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| MSH3 (Sus scrofa - pig) |
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| MSH3 (Chlorocebus sabaeus - green monkey) |
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| Msh3 (Heterocephalus glaber - naked mole-rat) |
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| Msh3 (Rattus rattus - black rat) |
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.
Variants in Msh3
1114 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| UniSTS:498245 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 67 | 162 | 91 | 90 | 59 | 91 | 59 | 6 | 355 | 191 | 11 | 141 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_001191957 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006231768 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006231769 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282325 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282326 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282327 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282328 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282329 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282330 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282331 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282332 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282333 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063282335 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | BC091283 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| JAXUCZ010000002 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000018449 ⟹ ENSRNOP00000018449 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000100720 ⟹ ENSRNOP00000077811 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000172709 ⟹ ENSRNOP00000109273 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001191957 ⟹ NP_001178886 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_063282325 ⟹ XP_063138395 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282326 ⟹ XP_063138396 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282327 ⟹ XP_063138397 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282328 ⟹ XP_063138398 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282329 ⟹ XP_063138399 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282330 ⟹ XP_063138400 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282331 ⟹ XP_063138401 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282332 ⟹ XP_063138402 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282333 ⟹ XP_063138403 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063282335 ⟹ XP_063138405 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_001178886 | (Get FASTA) | NCBI Sequence Viewer |
| XP_063138395 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138396 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138397 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138398 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138399 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138400 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138401 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138402 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138403 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063138405 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAH91283 | (Get FASTA) | NCBI Sequence Viewer |
| Ensembl Protein | ENSRNOP00000077811.1 | ||
| ENSRNOP00000109273 | |||
| ENSRNOP00000109273.1 |
| RefSeq Acc Id: | NP_001178886 ⟸ NM_001191957 |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000018449 ⟸ ENSRNOT00000018449 |
| RefSeq Acc Id: | XP_063138398 ⟸ XM_063282328 |
| - Peptide Label: | isoform X4 |
| RefSeq Acc Id: | XP_063138397 ⟸ XM_063282327 |
| - Peptide Label: | isoform X3 |
| RefSeq Acc Id: | XP_063138396 ⟸ XM_063282326 |
| - Peptide Label: | isoform X2 |
| RefSeq Acc Id: | XP_063138395 ⟸ XM_063282325 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_063138399 ⟸ XM_063282329 |
| - Peptide Label: | isoform X5 |
| RefSeq Acc Id: | XP_063138405 ⟸ XM_063282335 |
| - Peptide Label: | isoform X10 |
| RefSeq Acc Id: | XP_063138403 ⟸ XM_063282333 |
| - Peptide Label: | isoform X9 |
| RefSeq Acc Id: | XP_063138400 ⟸ XM_063282330 |
| - Peptide Label: | isoform X6 |
| - UniProtKB: | A6I4Q5 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063138402 ⟸ XM_063282332 |
| - Peptide Label: | isoform X8 |
| - UniProtKB: | A6I4Q5 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063138401 ⟸ XM_063282331 |
| - Peptide Label: | isoform X7 |
| - UniProtKB: | A6I4Q5 (UniProtKB/TrEMBL) |
| Ensembl Acc Id: | ENSRNOP00000077811 ⟸ ENSRNOT00000100720 |
| Ensembl Acc Id: | ENSRNOP00000109273 ⟸ ENSRNOT00000172709 |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-F1LQM8-F1-model_v2 | AlphaFold | F1LQM8 | 1-1104 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| RGD ID: | 13691056 | ||||||||
| Promoter ID: | EPDNEW_R1581 | ||||||||
| Type: | single initiation site | ||||||||
| Name: | Msh3_1 | ||||||||
| Description: | mutS homolog 3 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
|
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1563954 | AgrOrtholog |
| BioCyc Gene | G2FUF-54869 | BioCyc |
| Ensembl Genes | ENSRNOG00000013673 | Ensembl |
| ENSRNOG00000064838 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000100720.2 | UniProtKB/TrEMBL |
| ENSRNOT00000172709 | ENTREZGENE | |
| ENSRNOT00000172709.1 | UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.10.1420.10 | UniProtKB/TrEMBL |
| 3.40.50.300 | UniProtKB/TrEMBL | |
| DNA repair protein MutS, domain I | UniProtKB/TrEMBL | |
| MutS, connector domain | UniProtKB/TrEMBL | |
| IMAGE_CLONE | IMAGE:7302809 | IMAGE-MGC_LOAD |
| InterPro | DNA_mismatch_repair_MutS-lik_N | UniProtKB/TrEMBL |
| DNA_mismatch_repair_MutS_C | UniProtKB/TrEMBL | |
| DNA_mismatch_repair_MutS_core | UniProtKB/TrEMBL | |
| DNA_mismatch_repair_MutS_N | UniProtKB/TrEMBL | |
| DNA_mismatch_repair_MutS_sf | UniProtKB/TrEMBL | |
| DNA_mmatch_repair_MutS_con_dom | UniProtKB/TrEMBL | |
| MutS_con_dom_sf | UniProtKB/TrEMBL | |
| MutS_family | UniProtKB/TrEMBL | |
| P-loop_NTPase | UniProtKB/TrEMBL | |
| MGC_CLONE | MGC:109173 | IMAGE-MGC_LOAD |
| NCBI Gene | 499505 | ENTREZGENE |
| PANTHER | DNA MISMATCH REPAIR PROTEIN MSH3 | UniProtKB/TrEMBL |
| PTHR11361 | UniProtKB/TrEMBL | |
| Pfam | MutS_I | UniProtKB/TrEMBL |
| MutS_II | UniProtKB/TrEMBL | |
| MutS_III | UniProtKB/TrEMBL | |
| MutS_V | UniProtKB/TrEMBL | |
| PhenoGen | Msh3 | PhenoGen |
| PROSITE | DNA_MISMATCH_REPAIR_2 | UniProtKB/TrEMBL |
| RatGTEx | ENSRNOG00000013673 | RatGTEx |
| ENSRNOG00000064838 | RatGTEx | |
| SMART | MUTSac | UniProtKB/TrEMBL |
| MUTSd | UniProtKB/TrEMBL | |
| Superfamily-SCOP | DNA repair protein MutS, domain I | UniProtKB/TrEMBL |
| DNA repair protein MutS, domain II | UniProtKB/TrEMBL | |
| DNA repair protein MutS, domain III | UniProtKB/TrEMBL | |
| SSF52540 | UniProtKB/TrEMBL | |
| UniProt | A0A8I5YC19_RAT | UniProtKB/TrEMBL |
| A0ABK0LER1_RAT | UniProtKB/TrEMBL | |
| A6I4Q5 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q5BJY1_RAT | UniProtKB/TrEMBL |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2013-11-19 | Msh3 | mutS homolog 3 | Msh3 | mutS homolog 3 (E. coli) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2006-02-09 | Msh3 | mutS homolog 3 (E. coli) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |