Uqcrq (ubiquinol-cytochrome c reductase, complex III subunit VII) - Rat Genome Database

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Gene: Uqcrq (ubiquinol-cytochrome c reductase, complex III subunit VII) Rattus norvegicus
Analyze
Symbol: Uqcrq
Name: ubiquinol-cytochrome c reductase, complex III subunit VII
RGD ID: 1562350
Description: Predicted to be involved in brain development and mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex III. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Orthologous to human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: complex III subunit 8; complex III subunit VIII; cytochrome b-c1 complex subunit 8; low molecular mass ubiquinone-binding protein; Qpc; ubiquinol-cytochrome c reductase complex 9.5 kDa protein; ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,086,691 - 38,093,871 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1038,087,715 - 38,089,996 (-)EnsemblGRCr8
mRatBN7.21037,585,864 - 37,589,328 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1037,586,888 - 37,589,169 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1042,278,686 - 42,281,973 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01041,768,739 - 41,772,026 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01037,272,455 - 37,275,742 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01038,779,132 - 38,782,489 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,779,132 - 38,782,419 (-)Ensemblrn6Rnor6.0
Rnor_5.01038,561,411 - 38,564,771 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41038,889,265 - 38,892,552 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1036,933,353 - 36,936,640 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
apigenin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
chrysene  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
eugenol  (EXP)
fenpyroximate  (ISO)
flutamide  (ISO)
folic acid  (ISO)
furan  (EXP)
hydralazine  (ISO)
indometacin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
Mesaconitine  (EXP)
methidathion  (ISO)
ochratoxin A  (ISO)
osimertinib  (EXP)
oxybenzone  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
picoxystrobin  (ISO)
pyrimidifen  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP,ISO)
selenium atom  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
protein binding  (IPI,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles. Topalidou I, etal., PLoS Genet. 2016 May 18;12(5):e1006074. doi: 10.1371/journal.pgen.1006074. eCollection 2016 May.
Additional References at PubMed
PMID:12865426   PMID:14651853   PMID:16120479   PMID:16901643   PMID:18614015   PMID:28844695   PMID:29476059   PMID:32357304   PMID:35352799  


Genomics

Comparative Map Data
Uqcrq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,086,691 - 38,093,871 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1038,087,715 - 38,089,996 (-)EnsemblGRCr8
mRatBN7.21037,585,864 - 37,589,328 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1037,586,888 - 37,589,169 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1042,278,686 - 42,281,973 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01041,768,739 - 41,772,026 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01037,272,455 - 37,275,742 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01038,779,132 - 38,782,489 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,779,132 - 38,782,419 (-)Ensemblrn6Rnor6.0
Rnor_5.01038,561,411 - 38,564,771 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41038,889,265 - 38,892,552 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1036,933,353 - 36,936,640 (-)NCBICelera
Cytogenetic Map10q22NCBI
UQCRQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,866,642 - 132,868,847 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,866,626 - 132,868,847 (+)Ensemblhg38GRCh38
GRCh375132,202,334 - 132,204,539 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,230,218 - 132,232,435 (+)NCBIBuild 36Build 36hg18NCBI36
Celera5128,332,343 - 128,334,559 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5127,395,036 - 127,397,252 (+)NCBIHuRef
CHM1_15131,635,604 - 131,637,820 (+)NCBICHM1_1
T2T-CHM13v2.05133,386,396 - 133,388,600 (+)NCBIT2T-CHM13v2.0
Uqcrq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,318,749 - 53,321,658 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,318,749 - 53,321,658 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381153,427,922 - 53,430,831 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,427,922 - 53,430,831 (-)Ensemblmm10GRCm38
MGSCv371153,242,450 - 53,244,333 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361153,271,345 - 53,274,237 (-)NCBIMGSCv36mm8
Celera1158,008,668 - 58,010,551 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.94NCBI
LOC102006544
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554084,240,072 - 4,241,342 (+)Ensembl
ChiLan1.0NW_0049554084,240,072 - 4,241,342 (+)NCBIChiLan1.0ChiLan1.0
LOC100987427
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24128,179,446 - 128,180,251 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15126,318,678 - 126,319,815 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05128,283,869 - 128,285,010 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15134,442,880 - 134,444,006 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,442,883 - 134,444,020 (+)EnsemblpanPan2panpan1.1
UQCRQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11121,148,964 - 21,150,573 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,149,061 - 21,150,572 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1119,951,811 - 19,953,412 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01121,936,243 - 21,937,853 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1121,936,365 - 22,133,742 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11120,654,600 - 20,656,208 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01120,502,312 - 20,503,921 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01121,144,831 - 21,146,441 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101970096
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,346,390 - 115,347,871 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366472,348,835 - 2,381,645 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366472,349,152 - 2,350,570 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UQCRQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2135,186,501 - 135,188,293 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12135,186,366 - 135,188,237 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,654,907 - 140,656,750 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UQCRQ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,684,395 - 35,685,481 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,684,495 - 35,685,670 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603442,256,991 - 42,258,119 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101712532
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473339,233,359 - 39,234,945 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473339,233,359 - 39,235,008 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
LOC116909599
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1935,920,111 - 35,922,471 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Uqcrq
35 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:77
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000073964
Prediction methods:Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103589326352293000Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY323237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000073964   ⟹   ENSRNOP00000065074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1038,779,132 - 38,782,419 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100770   ⟹   ENSRNOP00000089793
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1038,087,715 - 38,089,996 (-)Ensembl
mRatBN7.2 Ensembl1037,586,888 - 37,589,169 (-)Ensembl
RefSeq Acc Id: NM_001025134   ⟹   NP_001020305
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81038,086,691 - 38,089,978 (-)NCBI
mRatBN7.21037,585,864 - 37,589,151 (-)NCBI
Rnor_6.01038,779,132 - 38,782,419 (-)NCBI
Rnor_5.01038,561,411 - 38,564,771 (-)NCBI
RGSC_v3.41038,889,265 - 38,892,552 (-)RGD
Celera1036,933,353 - 36,936,640 (-)RGD
Sequence:
RefSeq Acc Id: XM_006246316   ⟹   XP_006246378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81038,087,715 - 38,093,871 (-)NCBI
mRatBN7.21037,586,885 - 37,589,328 (-)NCBI
Rnor_6.01038,780,151 - 38,782,489 (-)NCBI
Rnor_5.01038,561,411 - 38,564,771 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001020305 (Get FASTA)   NCBI Sequence Viewer  
  XP_006246378 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP84717 (Get FASTA)   NCBI Sequence Viewer  
  EDM04381 (Get FASTA)   NCBI Sequence Viewer  
  EDM04382 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000089793
  ENSRNOP00000089793.1
GenBank Protein Q7TQ16 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020305   ⟸   NM_001025134
- UniProtKB: Q7TQ16 (UniProtKB/Swiss-Prot),   A6HEC7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246378   ⟸   XM_006246316
- Peptide Label: isoform X1
- UniProtKB: Q7TQ16 (UniProtKB/Swiss-Prot),   A6HEC7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065074   ⟸   ENSRNOT00000073964
Ensembl Acc Id: ENSRNOP00000089793   ⟸   ENSRNOT00000100770

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TQ16-F1-model_v2 AlphaFold Q7TQ16 1-82 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697176
Promoter ID:EPDNEW_R7701
Type:initiation region
Name:Uqcrq_1
Description:ubiquinol-cytochrome c reductase, complex III subunit VII
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01038,782,427 - 38,782,487EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562350 AgrOrtholog
BioCyc Gene G2FUF-25142 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000048174 Ensembl
  ENSRNOG00000067979 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000100770 ENTREZGENE
  ENSRNOT00000100770.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.210 UniProtKB/Swiss-Prot
InterPro Cyt_bc1_su8 UniProtKB/Swiss-Prot
  Cyt_bc1_su8_sf UniProtKB/Swiss-Prot
KEGG Report rno:497902 UniProtKB/Swiss-Prot
NCBI Gene 497902 ENTREZGENE
PANTHER CYTOCHROME B-C1 COMPLEX SUBUNIT 8 UniProtKB/Swiss-Prot
  PTHR12119 UniProtKB/Swiss-Prot
Pfam UcrQ UniProtKB/Swiss-Prot
PhenoGen Uqcrq PhenoGen
RatGTEx ENSRNOG00000048174 RatGTEx
  ENSRNOG00000067979 RatGTEx
Superfamily-SCOP SSF81508 UniProtKB/Swiss-Prot
UniProt A6HEC7 ENTREZGENE, UniProtKB/TrEMBL
  Q7TQ16 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Uqcrq  ubiquinol-cytochrome c reductase, complex III subunit VII  Qpc  low molecular mass ubiquinone-binding protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Qpc  low molecular mass ubiquinone-binding protein      Symbol and Name status set to provisional 70820 PROVISIONAL