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Gene: Pex1 (peroxisomal biogenesis factor 1) Rattus norvegicus

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Symbol:

Pex1

Name:

peroxisomal biogenesis factor 1

RGD ID:

1559939

Description:

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ubiquitin-modified protein reader activity. Predicted to be involved in protein import into peroxisome matrix; protein targeting to peroxisome; and protein unfolding. Predicted to act upstream of or within microtubule-based peroxisome localization and protein import into peroxisome matrix, receptor recycling. Located in peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Orthologous to human PEX1 (peroxisomal biogenesis factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC500006; peroxisomal ATPase PEX1; peroxisome biogenesis factor 1; RGD1559939; similar to peroxisome biogenesis factor 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PEX1 (peroxisomal biogenesis factor 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Pex1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pex1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PEX1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PEX1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pex1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PEX1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PEX1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pex1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pex1 (peroxisomal biogenesis factor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NOD2 (nucleotide binding oligomerization domain containing 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PEX1 (peroxisomal biogenesis factor 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pex1 (peroxisomal biogenesis factor 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pex1 (peroxisomal biogenesis factor 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PEX1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Pex1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	prx-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pex1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	31,474,670 - 31,513,621 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	31,470,845 - 31,513,811 (-)	Ensembl				GRCr8
mRatBN7.2	4	30,519,950 - 30,558,953 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	30,519,955 - 30,558,921 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	35,492,702 - 35,531,639 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	31,418,781 - 31,457,718 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	29,814,810 - 29,853,743 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	27,659,376 - 27,698,037 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	27,659,381 - 27,698,037 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	27,562,602 - 27,601,351 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	27,235,147 - 27,275,076 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	25,944,627 - 25,983,247 (-)	NCBI		Celera
Cytogenetic Map	4	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Developmental Disabilities (ISO)

epilepsy (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

Heimler syndrome 1 (ISO)

infantile Refsum disease (ISO)

Leber congenital amaurosis (ISO)

optic atrophy (ISO)

peroxisomal biogenesis disorder (ISO)

peroxisomal disease (ISO)

peroxisome biogenesis disorder 1A (ISO)

peroxisome biogenesis disorder 1B (ISO)

polymicrogyria (ISO)

retinitis pigmentosa 1 (ISO)

Zellweger Leukodystrophy (ISO)

Zellweger syndrome (ISO,ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amiodarone (ISO)

aspartame (ISO)

atrazine (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

caffeine (ISO)

CGP 52608 (ISO)

ciguatoxin CTX1B (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

elemental selenium (ISO)

epoxiconazole (ISO)

Erionite (ISO)

FR900359 (ISO)

fulvestrant (ISO)

hexadecanoic acid (ISO)

hydrogen peroxide (ISO)

lithium atom (ISO)

lithium hydride (ISO)

methapyrilene (EXP)

methidathion (ISO)

methyl methanesulfonate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

monosodium L-glutamate (ISO)

N(4)-hydroxycytidine (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (EXP,ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium fluoride (ISO)

Soman (EXP)

tamoxifen (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

vitamin E (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

microtubule-based peroxisome localization (ISO)

peroxisome organization (IEA,ISO)

protein import into peroxisome matrix (IBA,IEA,ISO)

protein import into peroxisome matrix, receptor recycling (IEA,ISO)

protein targeting to peroxisome (IEA,ISO)

protein transport (IEA)

protein unfolding (IBA,IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IBA,IEA,ISO)

membrane (IEA)

peroxisomal membrane (IBA,IDA,IEA,ISO)

peroxisome (IEA,ISO)

Molecular Function

ATP binding (IEA,ISO)

ATP hydrolysis activity (IBA,IEA,ISO)

hydrolase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein transporter activity (IEA,ISO)

protein-containing complex binding (IEA,ISO)

ubiquitin-modified protein reader activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Liver disease predominates in a mouse model for mild human Zellweger spectrum disorder.	Berendse K, etal., Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2774-2787. doi: 10.1016/j.bbadis.2019.06.013. Epub 2019 Jun 15.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	The Pex1-G844D mouse: a model for mild human Zellweger spectrum disorder.	Hiebler S, etal., Mol Genet Metab. 2014 Apr;111(4):522-532. doi: 10.1016/j.ymgme.2014.01.008. Epub 2014 Jan 23.
4.	Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.	Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:9398847	PMID:9588209	PMID:11439091	PMID:16449325	PMID:16854980	PMID:18570454	PMID:21525035	PMID:21980954	PMID:27826738

Genomics

Comparative Map Data

Pex1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	31,474,670 - 31,513,621 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	31,470,845 - 31,513,811 (-)	Ensembl				GRCr8
mRatBN7.2	4	30,519,950 - 30,558,953 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	30,519,955 - 30,558,921 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	35,492,702 - 35,531,639 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	31,418,781 - 31,457,718 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	29,814,810 - 29,853,743 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	27,659,376 - 27,698,037 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	27,659,381 - 27,698,037 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	27,562,602 - 27,601,351 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	27,235,147 - 27,275,076 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	25,944,627 - 25,983,247 (-)	NCBI		Celera
Cytogenetic Map	4	q13	NCBI

PEX1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	92,487,025 - 92,528,520 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	92,487,020 - 92,528,640 (-)	Ensembl			hg38	GRCh38
GRCh37	7	92,116,339 - 92,157,834 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	91,954,273 - 91,995,781 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	91,760,990 - 91,802,460	NCBI
Celera	7	86,820,874 - 86,862,377 (-)	NCBI		Celera
Cytogenetic Map	7	q21.2	NCBI
HuRef	7	86,725,109 - 86,766,599 (-)	NCBI		HuRef
CHM1_1	7	92,046,373 - 92,087,866 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	93,728,340 - 93,769,797 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	91,445,547 - 91,487,069 (-)	NCBI

Pex1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	3,646,066 - 3,687,230 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	3,646,066 - 3,687,232 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	3,596,066 - 3,637,230 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	3,596,066 - 3,637,232 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	3,596,066 - 3,637,101 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	3,602,072 - 3,643,107 (+)	NCBI		MGSCv36	mm8
Celera	5	3,532,126 - 3,572,649 (+)	NCBI		Celera
Cytogenetic Map	5	A1	NCBI
cM Map	5	2.26	NCBI

Pex1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955432	9,418,678 - 9,461,419 (-)	Ensembl
ChiLan1.0	NW_004955432	9,418,480 - 9,461,507 (-)	NCBI	ChiLan1.0	ChiLan1.0

PEX1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	110,372,447 - 110,413,736 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	158,635,150 - 158,678,317 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	84,484,965 - 84,526,309 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	98,081,018 - 98,122,335 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	98,081,021 - 98,122,335 (-)	Ensembl			panPan2	panpan1.1

PEX1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	18,073,759 - 18,144,489 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	18,073,758 - 18,143,152 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	17,634,623 - 17,705,370 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	17,880,526 - 17,951,301 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	17,880,343 - 17,922,507 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	18,041,002 - 18,111,759 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	17,753,220 - 17,823,831 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	18,027,289 - 18,098,075 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pex1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	31,459,732 - 31,507,925 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936803	1,291,702 - 1,340,178 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936803	1,291,867 - 1,340,123 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PEX1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	72,385,475 - 72,444,582 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	72,385,755 - 72,444,718 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	79,114,205 - 79,173,283 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PEX1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	56,493,424 - 56,535,565 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	56,493,435 - 56,535,154 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666042	47,744,820 - 47,787,087 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pex1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624809	668,345 - 712,743 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624809	668,248 - 713,036 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pex1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	135,872,638 - 135,913,294 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pex1
80 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	44
Count of miRNA genes:	40
Interacting mature miRNAs:	44
Transcripts:	ENSRNOT00000038136
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2302371	Stl22	Serum triglyceride level QTL 22	5.15		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	13080146	58080146	Rat
2303585	Bw86	Body weight QTL 86	4		body mass (VT:0001259)	body weight (CMO:0000012)	4	15644309	60644309	Rat
8552903	Pigfal2	Plasma insulin-like growth factor 1 level QTL 2	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	4	1	32668025	Rat
9590100	Sffal4	Serum free fatty acids level QTL 4	7.36	0.05	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	4	1	32668025	Rat
8552906	Pigfal3	Plasma insulin-like growth factor 1 level QTL 3			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	4	11038706	56038706	Rat
1357341	Gluco5	Glucose level QTL 5	6.4		adipocyte free fatty acid secretion trait (VT:0010465)	absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)	4	1	34142783	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
1357343	Gluco4	Glucose level QTL 4		0.00002	adipocyte glucose uptake trait (VT:0004185)	adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)	4	1	34142783	Rat
8552782	Vie1	Viral induced encephalitis QTL 1	26.4		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	1	35396961	Rat
6478766	Anxrr47	Anxiety related response QTL 47		0.09637	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	11038706	56038706	Rat
70222	Eae2	Experimental allergic encephalomyelitis QTL 2	4.3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	4	22288453	40471598	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	26234499	134199155	Rat
631642	Stl2	Serum triglyceride level QTL 2	3.3		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	5894575	57613242	Rat
6478769	Anxrr48	Anxiety related response QTL 48		0.02514	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	11038706	56038706	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	11706604	92690519	Rat
2313401	Anxrr27	Anxiety related response QTL 27			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	4	18900697	63900697	Rat
631209	Bw2	Body weight QTL2	4.2		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	1	45429897	Rat
8552803	Bw144	Body weight QTL 144	16		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	1	35396961	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	27862204	126119996	Rat
8694374	Bw155	Body weight QTL 155	3.39	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	4	11038706	56038706	Rat
8552801	Bw143	Body weight QTL 143	7.3		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	1	35396961	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5889999	148002343	Rat
9589046	Scfw2	Subcutaneous fat weight QTL 2	5.54	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	4	1	32668025	Rat
61412	Pia2	Pristane induced arthritis QTL 2	3.9		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	4	22288453	63245191	Rat
8552807	Vie4	Viral induced encephalitis QTL 4	7.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	18900697	63900697	Rat
6478724	Anxrr35	Anxiety related response QTL 35		0.00449	defecation behavior trait (VT:0010462)	defecation measurement (CMO:0000997)	4	11038706	56038706	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	30448961	82336920	Rat
61415	Eae11	Experimental allergic encephalomyelitis QTL 11	2.9		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	4	1	40471598	Rat
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	5889999	50889999	Rat
8552809	Vie5	Viral induced encephalitis QTL 5	25.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	1	35396961	Rat
7387227	Uae40	Urinary albumin excretion QTL 40	2.9	0.0052	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	18913151	63913151	Rat
6909122	Insul22	Insulin level QTL 22	4.63		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	4	27862204	62997402	Rat
738021	Hcar13	Hepatocarcinoma resistance QTL 13	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	4	1	33538816	Rat
1358203	Stl19	Serum triglyceride level QTL 19	2.8	0.002	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	21925151	66925151	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	1	63900697	Rat
9590304	Scort17	Serum corticosterone level QTL 17	4.96	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	11038706	56038706	Rat
9589097	Slep11	Serum leptin concentration QTL 11	5.09	0.001	blood leptin amount (VT:0005667)	plasma leptin level (CMO:0000781)	4	1	32668025	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
1354665	Stl10	Serum triglyceride level QTL 10	3.57		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	22288453	45429897	Rat
1300141	Bp178	Blood pressure QTL 178			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	10758701	40490708	Rat

Markers in Region

AI555451

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	4	31,476,615 - 31,477,061 (+)	Marker Load Pipeline
mRatBN7.2	4	30,521,895 - 30,522,341 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	27,661,322 - 27,661,767	NCBI	Rnor6.0
Rnor_5.0	4	27,564,548 - 27,564,993	UniSTS	Rnor5.0
RGSC_v3.4	4	27,237,088 - 27,237,533	UniSTS	RGSC3.4
Celera	4	25,946,568 - 25,947,013	UniSTS
RH 3.4 Map	4	168.9	UniSTS
Cytogenetic Map	4	q13	UniSTS

RH134880

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	30,520,050 - 30,520,251 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	27,659,477 - 27,659,677	NCBI	Rnor6.0
Rnor_5.0	4	27,562,703 - 27,562,903	UniSTS	Rnor5.0
RGSC_v3.4	4	27,235,243 - 27,235,443	UniSTS	RGSC3.4
Celera	4	25,944,723 - 25,944,923	UniSTS
RH 3.4 Map	4	169.29	UniSTS
Cytogenetic Map	4	q13	UniSTS

RH129188

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	30,519,674 - 30,519,870 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	27,659,101 - 27,659,296	NCBI	Rnor6.0
Rnor_5.0	4	27,562,327 - 27,562,522	UniSTS	Rnor5.0
RGSC_v3.4	4	27,234,867 - 27,235,062	UniSTS	RGSC3.4
Celera	4	25,944,347 - 25,944,542	UniSTS
RH 3.4 Map	4	169.2	UniSTS
Cytogenetic Map	4	q13	UniSTS

RH131152

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	30,547,446 - 30,547,630 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	27,686,610 - 27,686,793	NCBI	Rnor6.0
Rnor_5.0	4	27,589,843 - 27,590,026	UniSTS	Rnor5.0
RGSC_v3.4	4	27,263,545 - 27,263,728	UniSTS	RGSC3.4
Celera	4	25,971,798 - 25,971,981	UniSTS
Cytogenetic Map	4	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236054	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005503290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000038136 ⟹ ENSRNOP00000032605

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	31,470,845 - 31,513,811 (-)	Ensembl
mRatBN7.2 Ensembl	4	30,520,392 - 30,558,921 (-)	Ensembl
Rnor_6.0 Ensembl	4	27,659,381 - 27,698,037 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094008 ⟹ ENSRNOP00000090555

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	31,474,675 - 31,513,811 (-)	Ensembl
mRatBN7.2 Ensembl	4	30,520,392 - 30,558,921 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104070 ⟹ ENSRNOP00000093891

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	31,474,675 - 31,513,811 (-)	Ensembl
mRatBN7.2 Ensembl	4	30,519,955 - 30,549,442 (-)	Ensembl

RefSeq Acc Id:

NM_001109220 ⟹ NP_001102690

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	31,474,675 - 31,513,612 (-)	NCBI
mRatBN7.2	4	30,519,955 - 30,558,898 (-)	NCBI
Rnor_6.0	4	27,659,381 - 27,698,037 (-)	NCBI
Rnor_5.0	4	27,562,602 - 27,601,351 (-)	NCBI
RGSC_v3.4	4	27,235,147 - 27,275,076 (-)	RGD
Celera	4	25,944,627 - 25,983,247 (-)	RGD

Sequence:

show sequence

ATGTGGAGCAGTGATCGCTTAGCCGGTGCGGGGTCTGGTGGGGCGGTCGTGACGGTGGCCTTCA
CGAATGCTCGGGACTGCTTCCTCCATCTGCCACGGCACCTCGTGGCCCAGCTTCACCTGCTGCA
GAATCAAGCTATAGAAGTAACCGGGGATCACCAGCCTACCTACTTGAGCTGGGTGGAAGGCAGG
CATTTTAATGATCAAAGTGAAAATGTGGCAGAAATTAATAGACAAGTTGGCCAGAAGCTTGGAC
TCTCGAGCGGGGATCAGGTGTTTCTCAGGCCGTGTTCCCATGTGGTCTCATGCCAGCAGGTTGA
GGTGGAGCCTCTCTCGGCAGACGACTGGGAGATACTGGAGCTGCACGCCATTTCCCTTGAAGAA
CACCTTCTAGATCAGATTCGAATAGTTTTCCCTAAAGCCATCGTTCCCATCTGGGTTGACCAGC
AGACCTACATATTTATCCAAATTGTCGCTCTGATGCCAACTGCCCCTTATGGAAGGCTAGAAAC
TAACACCAAACTCCTTATTCAGCCAAAGACCCGCCAAGCCAAAGAGAGCACATTTCCAAAAGAA
GGCGATGCACGTGGACAAGCTCATAATTATGGGCGAGAACAGAAAGGAACGGTAAAGGAATTGC
AAACCAAGCAGCTTCATAAGAACACAGAGGCTGTCCCTGTATCTAATGGAAGAAACCCGGAAGT
CCCAGGTGACTCAGTGAAGCCACGCTGGTGGGCTGTGCTAGGAAGCATGTTTTCCTTTGGGCCT
GACAACAAACAAGAGTCAGCTTGGGGCTCATTGGAACTCGGTGCTTTCAAAAACATGCAGTCAC
AGACTGTCCCTCTAGACAGTATTTTCAGAGTGTGCCAAGTTCAGCCTCCTAGTGTGCATAACAC
CCCTGCTAACTCCGTGTTTCACAAACACTGCACCGTCCATGTATTTCCATGGGACCAAGAATAT
TTTGATGTGGAGCCCAGCTTTACTGTGGTCTATGGGAAACTAGTTAAGCTACATTCTCCAAAAC
AACAGCAGGACAAAAGTAAGCAGGGCGTCCTGTTACCTGAAAAAGAGAAGCAACTGTCCCAGTC
TCCAGGTCATAAGCGGATCGGCTCCGATGGCAGTGAGGAAGCTGCTGAGACCTGTGTGCTGAAG
GTAGTCTGGAATGGACTGGAGGAGCTGAAGAATGCCACGGAGTTCACCAAAAGTCTAGAGCCTC
TCCACCATGGGAAAGTCTGGATTCCAGCTGACCTGAGAAAGAGACTCAACATAGAAATGCATGC
AGTAGTCAGGATAACTCCACTGGAAACCACCCCTGTCATCCCAAGAGCCCTGAGATTACAACCT
GCAGAGAACTTACCTAGAGACGTGAGTGAAGAAGAGGTAAAAGCTGTGTTCTCATCGTGGCTAC
AGGAGTCTGCCACCACCATGTTTCCTTTGATAATATCAAAGCAAGAATGTATTAAGCTGGAAAT
TAAAGATGGGTTGAAAGAGTTCTCTCTGAGCATAGTTCATTCTCAGGAAAAAGAGAAGGAACAA
GGAAGAACTGTTTTTGTGTTGAGTCCCATTCTGCTGCAGAAGATCTCAGTACAAGTCCTTCTAG
AGCCCATGATCGGAGAACACAGTGAGGAAATTGACATTCTTCTTCCCTCTTTAACACTGAGCTC
TTTGGGCGGTGTGAGTTCCTTAAGTGTATCTGCCATGGAACACATCACTCACAGTCTCCTGGGA
CGCCCTTTGTCTCGGCAGCTGATGGCCCTCGTTGCCGGACTGAGGAATGGGGCTCTTTTGATCA
CTGGAGGAAAGGGAAGCGGGAAATCAACGTTAGCTAAAGCCATCTGTAAGGAAGCACATGACGC
TCTGGATGCCCACGTGGAGATGGTCGACTGCAAAGCTTTACGAGGAAAAAGGCTTGAAAGCATA
CAAAAAGCCCTAGAGGTGGCTTTCTCAGAGGCAGCCTGGAGGCAGCCATCCGTCATTCTGCTGG
ATGACCTGGACCTCATTGCTGGATTACCGAGCACCCCAGAGCATGAGCACAGCCCTGAAGCAGT
GCAGAGCCAACGGCTTGCACACGCTTTGAACAATATGATCAAAGAGTTTGTTTCCATGGGAAGC
TTGGTCGCGCTCATCGCCACGAGCCAGCTCCAGCACTCTCTCCATCCTTCCCTTGTCTCTGCTC
AAGGAGTCCACACATTTCAGTGCATCCAGCACATCCAGCCTCCTGATCAGGAACAGAGATGTGA
AATTCTGCATAGTGTTGTGAAGAATAAACTGGGCTGTGATATAAGCAAGTCCCCTGACTTGGAC
CTGAAGTGCATAGCTAAAGAGACGGAGGCGTTTGTGGCTCGAGACTTTACAGTTCTCGTGGACC
GAGCCATACACTCCTCTCTCTCTCGCCAGCAGAACCCCACCAGGGAAGGATTGACTTTAACAAC
AGCAGACTTCCAAAAGGCTCTCCGTGGATTTCTTCCTGCTTCTCTGCGAAATGTCAACTTGCAT
AAACCTAGAGACCTGGGCTGGGACAAGATCGGTGGATTACATGAAGTTCGGCAGATACTCATGG
ATACTATCCAGTTACCAGCCAAGTACCCAGAATTATTTGCAAACTTACCCATACGACAGAGGAC
GGGAATACTGCTTTATGGCCCTCCTGGGACAGGAAAAACTTTACTCGCTGGGGTGGTTGCAAGA
GAGAGTGGGATGAACTTTATTAGTATTCAGGGACCAGAGTTACTCAGCAAATACATTGGAGCAA
GTGAGCAAGCTGTTCGAGATGTCTTCATCAGAGCACAGGCTGCAAAGCCCTGTATTCTTTTCTT
TGATGAGTTTGAATCCATTGCTCCTCGAAGAGGTCATGACAACACAGGGGTTACAGACCGAGTA
GTTAACCAGTTGCTGACACAGTTAGATGGAGTAGAAGGCTTACAGGGAGTTTATGTGTTGGCTG
CTACTAGTCGCCCTGATTTGATTGACCCCGCCTTGTTACGGCCCGGCCGACTGGATAAATGTGT
ATACTGCCCTCCTCCAGATCAGGTGTCTCGTCTTGAGATTTTAACTGTCCTCAGCAAGTCTCTA
CCTCTGGCGGATGACGTGGACCTTCAGCACGTGGCCTCTGTCACTGAGTCCTTCACTGGAGCGG
ATCTGAAAGCTCTGCTGTACAATGCACAGCTGGAGGCCTTGCAGGGACGGCTACTGCCCGGCGG
GCTCCACGATGGAGGATCCAGCTCTGACAGTGACCTCAGTCTGTCTTCAATGGTCTTTCTTAAC
CACAGCAGTGGTTCCGACGACTCAGCTGGAGATGGAGAATGTGGCTTAGATCAATCCCTCGTTT
CTCTCGAGATGTCGGAGATCCTTCCAGATGAATCAAAATTCAATATGTACCGGCTGTACTTTGG
CAGCTCCTATGAATCGGAACTTGGAAACGGAGCCTCTTGTGACTTGAGCTCACACTGTCTGTCT
GCACCGAGCTCCATGACTCAGGACTTACCTGCCACTCCTGGGAAAGACCCATTGTTTACACAGC
ATCCTGTGTTCAGGACACCTTCCCAAGAAGGCTCCCAAGACCTTACACAGGAGCAGAGAGACCA
GCTGAGAGCAGACATCAGCATCATCAAAGGCAGATACCAGAGCCAAAGTGGAGAGGATGAATCC
CTTAACCAGCCTGGACCAATCAAAACCAGTTTTGCTATTAGTCAGGCACATTTAATGACTGCGC
TTGCCCACACGAGACCGTCCATTAATGAGGATGAAGGCAAGGAATTTGCTGAGCTGTATGAAAA
CTTTCAAAATCCGAAGAAGAGAAAAAATCAAAGTGGAACAGTGTTTCGAACTGGACAGAAAGTA
ACGTTAGCATAAAATACACTTCTGATTTTTCTAGATGTGTCTGCTCTGATGGTCTGTCCCTAAG
TTGTAACTATAAGAACGATGTATAGATTTTAATTTAATAAATCTGGTTAATCTATAAAATCACA
GAATGGTAAGTGCTGTGATTGCACAATGCTCAGGACTATCTGAGATCAATAGTGCAGGCTAAAT
GGGGTTATTTGTAAGAGATGGTGTTTTGTCCCTCAGTCTGTATTAAGTCCTCAATGGTCTTATG
TCAGTGGCAGAGCTCATTTGCTCTCCTTCAGAGGGATGCATTTCTTGGCACTCACAGACCCAGA
GTCACTGTTTTTCTAGCTCCTGGCAGATTGTATGCCTTGCAACTTCTTGACTGTTTTGGAAAAA
GATATATTCTATTATCTTCTTTTTTTTTGTTTTTAATCAGAACATAACATTTACACATAATTCA
AATAAATTTAATCCCTTCAACC

hide sequence

RefSeq Acc Id:

XM_006236054 ⟹ XP_006236116

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	31,474,670 - 31,513,621 (-)	NCBI
mRatBN7.2	4	30,519,950 - 30,558,906 (-)	NCBI
Rnor_6.0	4	27,659,376 - 27,697,996 (-)	NCBI
Rnor_5.0	4	27,562,602 - 27,601,351 (-)	NCBI

Sequence:

show sequence

GGCGGTCGTGACGGTGGCCTTCACGAATGCTCGGGACTGCTTCCTCCATCTGCCACGGCACCTC
GTGGCCCAGCTTCACCTGCTGCAGGTGCTTATCTGAATCCAGAGGGAAAAAACCATAAAAGTTA
TAAACTCCCTTTCTCTCCCATTGTTTGGATAAATAGAATCAAGCTATAGAAGTAACCGGGGATC
ACCAGCCTACCTACTTGAGCTGGGTGGAAGGCAGGCATTTTAATGATCAAAGTGAAAATGTGGC
AGAAATTAATAGACAAGTTGGCCAGAAGCTTGGACTCTCGAGCGGGGATCAGGTGTTTCTCAGG
CCGTGTTCCCATGTGGTCTCATGCCAGCAGGTTGAGGTGGAGCCTCTCTCGGCAGACGACTGGG
AGATACTGGAGCTGCACGCCATTTCCCTTGAAGAACACCTTCTAGATCAGATTCGAATAGTTTT
CCCTAAAGCCATCGTTCCCATCTGGGTTGACCAGCAGACCTACATATTTATCCAAATTGTCGCT
CTGATGCCAACTGCCCCTTATGGAAGGCTAGAAACTAACACCAAACTCCTTATTCAGCCAAAGA
CCCGCCAAGCCAAAGAGAGCACATTTCCAAAAGAAGGCGATGCACGTGGACAAGCTCATAATTA
TGGGCGAGAACAGAAAGGAACGGTAAAGGAATTGCAAACCAAGCAGCTTCATAAGAACACAGAG
GCTGTCCCTGTATCTAATGGAAGAAACCCGGAAGTCCCAGGTGACTCAGTGAAGCCACGCTGGT
GGGCTGTGCTAGGAAGCATGTTTTCCTTTGGGCCTGACAACAAACAAGAGTCAGCTTGGGGCTC
ATTGGAACTCGGTGCTTTCAAAAACATGCAGTCACAGACTGTCCCTCTAGACAGTATTTTCAGA
GTGTGCCAAGTTCAGCCTCCTAGTGTGCATAACACCCCTGCTAACTCCGTGTTTCACAAACACT
GCACCGTCCATGTATTTCCATGGGACCAAGAATATTTTGATGTGGAGCCCAGCTTTACTGTGGT
CTATGGGAAACTAGTTAAGCTACATTCTCCAAAACAACAGCAGGACAAAAGTAAGCAGGGCGTC
CTGTTACCTGAAAAAGAGAAGCAACTGTCCCAGTCTCCAGGTCATAAGCGGATCGGCTCCGATG
GCAGTGAGGAAGCTGCTGAGACCTGTGTGCTGAAGGTAGTCTGGAATGGACTGGAGGAGCTGAA
GAATGCCACGGAGTTCACCAAAAGTCTAGAGCCTCTCCACCATGGGAAAGTCTGGATTCCAGCT
GACCTGAGAAAGAGACTCAACATAGAAATGCATGCAGTAGTCAGGATAACTCCACTGGAAACCA
CCCCTGTCATCCCAAGAGCCCTGAGATTACAACCTGCAGAGAACTTACCTAGAGACGTGAGTGA
AGAAGAGGTAAAAGCTGTGTTCTCATCGTGGCTACAGGAGTCTGCCACCACCATGTTTCCTTTG
ATAATATCAAAGCAAGAATGTATTAAGCTGGAAATTAAAGATGGGTTGAAAGAGTTCTCTCTGA
GCATAGTTCATTCTCAGGAAAAAGAGAAGGAACAAGGAAGAACTGTTTTTGTGTTGAGTCCCAT
TCTGCTGCAGAAGATCTCAGTACAAGTCCTTCTAGAGCCCATGATCGGAGAACACAGTGAGGAA
ATTGACATTCTTCTTCCCTCTTTAACACTGAGCTCTTTGGGCGGTGTGAGTTCCTTAAGTGTAT
CTGCCATGGAACACATCACTCACAGTCTCCTGGGACGCCCTTTGTCTCGGCAGCTGATGGCCCT
CGTTGCCGGACTGAGGAATGGGGCTCTTTTGATCACTGGAGGAAAGGGAAGCGGGAAATCAACG
TTAGCTAAAGCCATCTGTAAGGAAGCACATGACGCTCTGGATGCCCACGTGGAGATGGTCGACT
GCAAAGCTTTACGAGGAAAAAGGCTTGAAAGCATACAAAAAGCCCTAGAGGTGGCTTTCTCAGA
GGCAGCCTGGAGGCAGCCATCCGTCATTCTGCTGGATGACCTGGACCTCATTGCTGGATTACCG
AGCACCCCAGAGCATGAGCACAGCCCTGAAGCAGTGCAGAGCCAACGGCTTGCACACGCTTTGA
ACAATATGATCAAAGAGTTTGTTTCCATGGGAAGCTTGGTCGCGCTCATCGCCACGAGCCAGCT
CCAGCACTCTCTCCATCCTTCCCTTGTCTCTGCTCAAGGAGTCCACACATTTCAGTGCATCCAG
CACATCCAGCCTCCTGATCAGGAACAGAGATGTGAAATTCTGCATAGTGTTGTGAAGAATAAAC
TGGGCTGTGATATAAGCAAGTCCCCTGACTTGGACCTGAAGTGCATAGCTAAAGAGACGGAGGC
GTTTGTGGCTCGAGACTTTACAGTTCTCGTGGACCGAGCCATACACTCCTCTCTCTCTCGCCAG
CAGAACCCCACCAGGGAAGGATTGACTTTAACAACAGCAGACTTCCAAAAGGCTCTCCGTGGAT
TTCTTCCTGCTTCTCTGCGAAATGTCAACTTGCATAAACCTAGAGACCTGGGCTGGGACAAGAT
CGGTGGATTACATGAAGTTCGGCAGATACTCATGGATACTATCCAGTTACCAGCCAAGTACCCA
GAATTATTTGCAAACTTACCCATACGACAGAGGACGGGAATACTGCTTTATGGCCCTCCTGGGA
CAGGAAAAACTTTACTCGCTGGGGTGGTTGCAAGAGAGAGTGGGATGAACTTTATTAGTATTCA
GGGACCAGAGTTACTCAGCAAATACATTGGAGCAAGTGAGCAAGCTGTTCGAGATGTCTTCATC
AGAGCACAGGCTGCAAAGCCCTGTATTCTTTTCTTTGATGAGTTTGAATCCATTGCTCCTCGAA
GAGGTCATGACAACACAGGGGTTACAGACCGAGTAGTTAACCAGTTGCTGACACAGTTAGATGG
AGTAGAAGGCTTACAGGGAGTTTATGTGTTGGCTGCTACTAGTCGCCCTGATTTGATTGACCCC
GCCTTGTTACGGCCCGGCCGACTGGATAAATGTGTATACTGCCCTCCTCCAGATCAGGTGTCTC
GTCTTGAGATTTTAACTGTCCTCAGCAAGTCTCTACCTCTGGCGGATGACGTGGACCTTCAGCA
CGTGGCCTCTGTCACTGAGTCCTTCACTGGAGCGGATCTGAAAGCTCTGCTGTACAATGCACAG
CTGGAGGCCTTGCAGGGACGGCTACTGCCCGGCGGGCTCCACGATGGAGGATCCAGCTCTGACA
GTGACCTCAGTCTGTCTTCAATGGTCTTTCTTAACCACAGCAGTGGTTCCGACGACTCAGCTGG
AGATGGAGAATGTGGCTTAGATCAATCCCTCGTTTCTCTCGAGATGTCGGAGATCCTTCCAGAT
GAATCAAAATTCAATATGTACCGGCTGTACTTTGGCAGCTCCTATGAATCGGAACTTGGAAACG
GAGCCTCTTGTGACTTGAGCTCACACTGTCTGTCTGCACCGAGCTCCATGACTCAGGACTTACC
TGCCACTCCTGGGAAAGACCCATTGTTTACACAGCATCCTGTGTTCAGGACACCTTCCCAAGAA
GGCTCCCAAGACCTTACACAGGAGCAGAGAGACCAGCTGAGAGCAGACATCAGCATCATCAAAG
GCAGATACCAGAGCCAAAGTGGAGAGGATGAATCCCTTAACCAGCCTGGACCAATCAAAACCAG
TTTTGCTATTAGTCAGGCACATTTAATGACTGCGCTTGCCCACACGAGACCGTCCATTAATGAG
GATGAAGGCAAGGAATTTGCTGAGCTGTATGAAAACTTTCAAAATCCGAAGAAGAGAAAAAATC
AAAGTGGAACAGTGTTTCGAACTGGACAGAAAGTAACGTTAGCATAAAATACACTTCTGATTTT
TCTAGATGTGTCTGCTCTGATGGTCTGTCCCTAAGTTGTAACTATAAGAACGATGTATAGATTT
TAATTTAATAAATCTGGTTAATCTATAAAATCACAGAATGGTAAGTGCTGTGATTGCACAATGC
TCAGGACTATCTGAGATCAATAGTGCAGGCTAAATGGGGTTATTTGTAAGAGATGGTGTTTTGT
CCCTCAGTCTGTATTAAGTCCTCAATGGTCTTATGTCAGTGGCAGAGCTCATTTGCTCTCCTTC
AGAGGGATGCATTTCTTGGCACTCACAGACCCAGAGTCACTGTTTTTCTAGCTCCTGGCAGATT
GTATGCCTTGCAACTTCTTGACTGTTTTGGAAAAAGATATATTCTATTATCTTCTTTTTTTTTG
TTTTTAATCAGAACATAACATTTACACATAATTCAAATAAATTTAATCCCTTCAACCAAAAA

hide sequence

RefSeq Acc Id:

XM_039108094 ⟹ XP_038964022

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	31,474,670 - 31,499,171 (-)	NCBI
mRatBN7.2	4	30,519,950 - 30,544,452 (-)	NCBI

RefSeq Acc Id:

XM_039108095 ⟹ XP_038964023

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	31,487,667 - 31,513,618 (-)	NCBI
mRatBN7.2	4	30,532,942 - 30,558,953 (-)	NCBI

RefSeq Acc Id:

XR_005503290

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	31,480,756 - 31,513,618 (-)	NCBI
mRatBN7.2	4	30,525,920 - 30,558,953 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102690	(Get FASTA)	NCBI Sequence Viewer
	XP_006236116	(Get FASTA)	NCBI Sequence Viewer
	XP_038964022	(Get FASTA)	NCBI Sequence Viewer
	XP_038964023	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL84367	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032605.4
	ENSRNOP00000090555.1
	ENSRNOP00000093891
	ENSRNOP00000093891.2

RefSeq Acc Id:

NP_001102690 ⟸ NM_001109220

- UniProtKB:

D3ZZB2 (UniProtKB/TrEMBL), A6K285 (UniProtKB/TrEMBL), A0A8I6ADS4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MWSSDRLAGAGSGGAVVTVAFTNARDCFLHLPRHLVAQLHLLQNQAIEVTGDHQPTYLSWVEGR
HFNDQSENVAEINRQVGQKLGLSSGDQVFLRPCSHVVSCQQVEVEPLSADDWEILELHAISLEE
HLLDQIRIVFPKAIVPIWVDQQTYIFIQIVALMPTAPYGRLETNTKLLIQPKTRQAKESTFPKE
GDARGQAHNYGREQKGTVKELQTKQLHKNTEAVPVSNGRNPEVPGDSVKPRWWAVLGSMFSFGP
DNKQESAWGSLELGAFKNMQSQTVPLDSIFRVCQVQPPSVHNTPANSVFHKHCTVHVFPWDQEY
FDVEPSFTVVYGKLVKLHSPKQQQDKSKQGVLLPEKEKQLSQSPGHKRIGSDGSEEAAETCVLK
VVWNGLEELKNATEFTKSLEPLHHGKVWIPADLRKRLNIEMHAVVRITPLETTPVIPRALRLQP
AENLPRDVSEEEVKAVFSSWLQESATTMFPLIISKQECIKLEIKDGLKEFSLSIVHSQEKEKEQ
GRTVFVLSPILLQKISVQVLLEPMIGEHSEEIDILLPSLTLSSLGGVSSLSVSAMEHITHSLLG
RPLSRQLMALVAGLRNGALLITGGKGSGKSTLAKAICKEAHDALDAHVEMVDCKALRGKRLESI
QKALEVAFSEAAWRQPSVILLDDLDLIAGLPSTPEHEHSPEAVQSQRLAHALNNMIKEFVSMGS
LVALIATSQLQHSLHPSLVSAQGVHTFQCIQHIQPPDQEQRCEILHSVVKNKLGCDISKSPDLD
LKCIAKETEAFVARDFTVLVDRAIHSSLSRQQNPTREGLTLTTADFQKALRGFLPASLRNVNLH
KPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVAR
ESGMNFISIQGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRV
VNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSKSL
PLADDVDLQHVASVTESFTGADLKALLYNAQLEALQGRLLPGGLHDGGSSSDSDLSLSSMVFLN
HSSGSDDSAGDGECGLDQSLVSLEMSEILPDESKFNMYRLYFGSSYESELGNGASCDLSSHCLS
APSSMTQDLPATPGKDPLFTQHPVFRTPSQEGSQDLTQEQRDQLRADISIIKGRYQSQSGEDES
LNQPGPIKTSFAISQAHLMTALAHTRPSINEDEGKEFAELYENFQNPKKRKNQSGTVFRTGQKV
TLA

hide sequence

RefSeq Acc Id:	XP_006236116 ⟸ XM_006236054
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ALA5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPTAPYGRLETNTKLLIQPKTRQAKESTFPKEGDARGQAHNYGREQKGTVKELQTKQLHKNTEA VPVSNGRNPEVPGDSVKPRWWAVLGSMFSFGPDNKQESAWGSLELGAFKNMQSQTVPLDSIFRV CQVQPPSVHNTPANSVFHKHCTVHVFPWDQEYFDVEPSFTVVYGKLVKLHSPKQQQDKSKQGVL LPEKEKQLSQSPGHKRIGSDGSEEAAETCVLKVVWNGLEELKNATEFTKSLEPLHHGKVWIPAD LRKRLNIEMHAVVRITPLETTPVIPRALRLQPAENLPRDVSEEEVKAVFSSWLQESATTMFPLI ISKQECIKLEIKDGLKEFSLSIVHSQEKEKEQGRTVFVLSPILLQKISVQVLLEPMIGEHSEEI DILLPSLTLSSLGGVSSLSVSAMEHITHSLLGRPLSRQLMALVAGLRNGALLITGGKGSGKSTL AKAICKEAHDALDAHVEMVDCKALRGKRLESIQKALEVAFSEAAWRQPSVILLDDLDLIAGLPS TPEHEHSPEAVQSQRLAHALNNMIKEFVSMGSLVALIATSQLQHSLHPSLVSAQGVHTFQCIQH IQPPDQEQRCEILHSVVKNKLGCDISKSPDLDLKCIAKETEAFVARDFTVLVDRAIHSSLSRQQ NPTREGLTLTTADFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPE LFANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIQGPELLSKYIGASEQAVRDVFIR AQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPA LLRPGRLDKCVYCPPPDQVSRLEILTVLSKSLPLADDVDLQHVASVTESFTGADLKALLYNAQL EALQGRLLPGGLHDGGSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLDQSLVSLEMSEILPDE SKFNMYRLYFGSSYESELGNGASCDLSSHCLSAPSSMTQDLPATPGKDPLFTQHPVFRTPSQEG SQDLTQEQRDQLRADISIIKGRYQSQSGEDESLNQPGPIKTSFAISQAHLMTALAHTRPSINED EGKEFAELYENFQNPKKRKNQSGTVFRTGQKVTLA hide sequence

Ensembl Acc Id:

ENSRNOP00000032605 ⟸ ENSRNOT00000038136

RefSeq Acc Id:	XP_038964022 ⟸ XM_039108094
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038964023 ⟸ XM_039108095
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000090555 ⟸ ENSRNOT00000094008

Ensembl Acc Id:

ENSRNOP00000093891 ⟸ ENSRNOT00000104070

Protein Domains

AAA+ ATPase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZZB2-F1-model_v2	AlphaFold	D3ZZB2	1-1283	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692847

Promoter ID:

EPDNEW_R3372

Type:

initiation region

Name:

Pex1_1

Description:

peroxisomal biogenesis factor 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	27,698,038 - 27,698,098	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1559939	AgrOrtholog
BioCyc Gene	G2FUF-45763	BioCyc
Ensembl Genes	ENSRNOG00000025991	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038136.5	UniProtKB/TrEMBL
	ENSRNOT00000094008.2	UniProtKB/TrEMBL
	ENSRNOT00000104070	ENTREZGENE
	ENSRNOT00000104070.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.8.60	UniProtKB/TrEMBL
	2.40.40.20	UniProtKB/TrEMBL
	3.10.330.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	AAA_ATPase_domain	UniProtKB/TrEMBL
	AAA_lid_3	UniProtKB/TrEMBL
	Asp_de-COase-like_fold	UniProtKB/TrEMBL
	ATPase_AAA+_core	UniProtKB/TrEMBL
	ATPase_AAA_core	UniProtKB/TrEMBL
	ATPase_AAA_CS	UniProtKB/TrEMBL
	CDC48_domain_2-like	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Peroxisome_synth_fac_1_a/b	UniProtKB/TrEMBL
	PEX-1N	UniProtKB/TrEMBL
KEGG Report	rno:500006	UniProtKB/TrEMBL
NCBI Gene	500006	ENTREZGENE
PANTHER	AAA-FAMILY ATPASE	UniProtKB/TrEMBL
	PTHR23077:SF12	UniProtKB/TrEMBL
Pfam	AAA	UniProtKB/TrEMBL
	AAA_lid_3	UniProtKB/TrEMBL
	PEX-1N	UniProtKB/TrEMBL
	PEX-2N	UniProtKB/TrEMBL
PhenoGen	Pex1	PhenoGen
PROSITE	AAA	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000025991	RatGTEx
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	Asp_decarb_fold	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
	SSF54585	UniProtKB/TrEMBL
UniProt	A0A8I6ADS4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ALA5	ENTREZGENE, UniProtKB/TrEMBL
	A6K285	ENTREZGENE, UniProtKB/TrEMBL
	D3ZZB2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-04-23	Pex1	peroxisomal biogenesis factor 1	Pex1	peroxisome biogenesis factor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-24	Pex1	peroxisome biogenesis factor 1	Pex1	peroxisomal biogenesis factor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-03	Pex1	peroxisomal biogenesis factor 1	Pex1	peroxisome biogenesis factor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-28	Pex1	peroxisome biogenesis factor 1	RGD1559939_predicted	similar to peroxisome biogenesis factor 1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1559939_predicted	similar to peroxisome biogenesis factor 1 (predicted)	LOC500006	similar to peroxisome biogenesis factor 1	Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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