Isyna1 (inositol-3-phosphate synthase 1) - Rat Genome Database

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Gene: Isyna1 (inositol-3-phosphate synthase 1) Rattus norvegicus
Analyze
Symbol: Isyna1
Name: inositol-3-phosphate synthase 1
RGD ID: 1359423
Description: Enables inositol-3-phosphate synthase activity. Involved in inositol biosynthetic process and negative regulation of inositol biosynthetic process. Predicted to be active in cytoplasm. Orthologous to human ISYNA1 (inositol-3-phosphate synthase 1); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IPS 1; LOC290651; MI-1-P synthase; MIP synthase; myo-inositol 1-phosphate synthase A1; myo-inositol-1-phosphate synthase; similar to myo-inositol 1-phosphate synthase A1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,873,119 - 18,876,116 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1618,873,121 - 18,875,955 (-)EnsemblGRCr8
mRatBN7.21618,839,143 - 18,841,979 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,839,145 - 18,841,979 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1618,880,839 - 18,883,671 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,013,623 - 20,016,455 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,933,801 - 18,936,633 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,589,497 - 20,592,333 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,589,481 - 20,592,449 (-)Ensemblrn6Rnor6.0
Rnor_5.01620,445,206 - 20,448,042 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,345,305 - 19,348,141 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1619,030,610 - 19,033,446 (-)NCBICelera
RGSC_v3.11619,345,311 - 19,348,054 (-)NCBI
Cytogenetic Map16p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP,ISO)
diclofenac  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
fenvalerate  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen cyanide  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
L-ethionine  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
lovastatin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
naphthalene  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nimesulide  (EXP)
Nutlin-3  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium cyanide  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
streptozocin  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thapsigargin  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (EXP)
trovafloxacin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vitamin E  (ISO)
warfarin  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Purification, structure, and catalytic properties of L-myo-inositol-1-phosphate synthase from rat testis. Maeda T and Eisenberg F, J Biol Chem. 1980 Sep 25;255(18):8458-64.
3. Rat brain myo-inositol 3-phosphate synthase is a phosphoprotein. Parthasarathy RN, etal., Mol Cell Biochem. 2013 Jun;378(1-2):83-9. doi: 10.1007/s11010-013-1597-7. Epub 2013 Mar 16.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Identification of myo-inositol-3-phosphate synthase isoforms: characterization, expression, and putative role of a 16-kDa gamma(c) isoform. Seelan RS, etal., J Biol Chem. 2009 Apr 3;284(14):9443-57. doi: 10.1074/jbc.M900206200. Epub 2009 Feb 2.
9. Incubations of testis myo-inositol-1-phosphate synthase with D-(5-18O)glucose 6-phosphate and with H218O show no evidence of Schiff base formation. Sherman WR, etal., J Biol Chem. 1977 Aug 25;252(16):5672-6.
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:21841945   PMID:23902760   PMID:30053369  


Genomics

Comparative Map Data
Isyna1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,873,119 - 18,876,116 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1618,873,121 - 18,875,955 (-)EnsemblGRCr8
mRatBN7.21618,839,143 - 18,841,979 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,839,145 - 18,841,979 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1618,880,839 - 18,883,671 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,013,623 - 20,016,455 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,933,801 - 18,936,633 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,589,497 - 20,592,333 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,589,481 - 20,592,449 (-)Ensemblrn6Rnor6.0
Rnor_5.01620,445,206 - 20,448,042 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,345,305 - 19,348,141 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1619,030,610 - 19,033,446 (-)NCBICelera
RGSC_v3.11619,345,311 - 19,348,054 (-)NCBI
Cytogenetic Map16p14NCBI
ISYNA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,434,388 - 18,438,133 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,434,388 - 18,438,178 (-)Ensemblhg38GRCh38
GRCh371918,545,198 - 18,548,943 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,406,625 - 18,409,943 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1918,447,020 - 18,450,933 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,108,499 - 18,112,412 (-)NCBIHuRef
CHM1_11918,545,346 - 18,549,259 (-)NCBICHM1_1
T2T-CHM13v2.01918,568,567 - 18,572,312 (-)NCBIT2T-CHM13v2.0
Isyna1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,047,131 - 71,049,940 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,047,023 - 71,049,940 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38870,594,481 - 70,597,290 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,594,373 - 70,597,290 (+)Ensemblmm10GRCm38
MGSCv37873,118,380 - 73,121,189 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36873,523,470 - 73,526,279 (+)NCBIMGSCv36mm8
Celera873,150,596 - 73,153,405 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Isyna1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,098,995 - 3,100,454 (+)Ensembl
ChiLan1.0NW_0049555243,099,017 - 3,100,454 (+)NCBIChiLan1.0ChiLan1.0
ISYNA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,295,288 - 23,299,230 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,303,623 - 22,307,529 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,913,400 - 17,916,789 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,884,406 - 18,887,931 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,884,412 - 18,887,931 (-)EnsemblpanPan2panpan1.1
ISYNA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,594,816 - 44,598,495 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,489,219 - 44,598,497 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2044,509,230 - 44,512,910 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02045,080,806 - 45,084,487 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,999,052 - 45,085,082 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,318,111 - 44,321,783 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,728,243 - 44,731,923 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,003,669 - 45,007,342 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Isyna1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,266,570 - 203,269,890 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,815,821 - 2,819,020 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,815,782 - 2,819,100 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ISYNA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,363,716 - 59,367,002 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1259,363,672 - 59,367,003 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ISYNA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,906,724 - 16,910,194 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,905,472 - 16,910,030 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660742,431,203 - 2,435,020 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Isyna1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,658,512 - 1,661,640 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249081,658,512 - 1,661,507 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Isyna1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11312,841,071 - 12,843,978 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Isyna1
14 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:37
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000026821
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161574800625801629Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)161627818427244292Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
RH129421  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,839,160 - 18,839,326 (+)MAPPERmRatBN7.2
Rnor_6.01620,589,515 - 20,589,680NCBIRnor6.0
Rnor_5.01620,445,224 - 20,445,389UniSTSRnor5.0
RGSC_v3.41619,345,323 - 19,345,488UniSTSRGSC3.4
Celera1619,030,628 - 19,030,793UniSTS
RH 3.4 Map16180.5UniSTS
Cytogenetic Map16p14UniSTS
RH130875  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,838,677 - 18,838,866 (+)MAPPERmRatBN7.2
Rnor_6.01620,589,032 - 20,589,220NCBIRnor6.0
Rnor_5.01620,444,741 - 20,444,929UniSTSRnor5.0
RGSC_v3.41619,344,840 - 19,345,028UniSTSRGSC3.4
Celera1619,030,145 - 19,030,333UniSTS
RH 3.4 Map16180.3UniSTS
Cytogenetic Map16p14UniSTS
UniSTS:498303  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81618,874,300 - 18,874,583 (+)Marker Load Pipeline
mRatBN7.21618,840,324 - 18,840,607 (+)MAPPERmRatBN7.2
Rnor_6.01620,590,679 - 20,590,961NCBIRnor6.0
Rnor_5.01620,446,388 - 20,446,670UniSTSRnor5.0
RGSC_v3.41619,346,487 - 19,346,769UniSTSRGSC3.4
Celera1619,031,792 - 19,032,074UniSTS
Cytogenetic Map16p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000026821   ⟹   ENSRNOP00000026821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1618,873,121 - 18,875,955 (-)Ensembl
mRatBN7.2 Ensembl1618,839,145 - 18,841,979 (-)Ensembl
Rnor_6.0 Ensembl1620,589,481 - 20,592,449 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000130564   ⟹   ENSRNOP00000103755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1618,873,121 - 18,875,955 (-)Ensembl
RefSeq Acc Id: NM_001013880   ⟹   NP_001013902
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,873,119 - 18,875,955 (-)NCBI
mRatBN7.21618,839,143 - 18,841,979 (-)NCBI
Rnor_6.01620,589,497 - 20,592,333 (-)NCBI
Rnor_5.01620,445,206 - 20,448,042 (-)NCBI
RGSC_v3.41619,345,305 - 19,348,141 (-)RGD
Celera1619,030,610 - 19,033,446 (-)RGD
Sequence:
RefSeq Acc Id: XM_063275161   ⟹   XP_063131231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,873,123 - 18,876,116 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001013902 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131231 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL90710 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000026821
  ENSRNOP00000026821.3
GenBank Protein Q6AYK3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001013902   ⟸   NM_001013880
- UniProtKB: Q6AYK3 (UniProtKB/Swiss-Prot),   A6KA27 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026821   ⟸   ENSRNOT00000026821
RefSeq Acc Id: XP_063131231   ⟸   XM_063275161
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000103755   ⟸   ENSRNOT00000130564
Protein Domains
Myo-inositol-1-phosphate synthase GAPDH-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYK3-F1-model_v2 AlphaFold Q6AYK3 1-557 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700024
Promoter ID:EPDNEW_R10547
Type:initiation region
Name:Isyna1_1
Description:inositol-3-phosphate synthase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,592,279 - 20,592,339EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359423 AgrOrtholog
BioCyc Gene G2FUF-11788 BioCyc
BioCyc Pathway PWY-2301 [myo-inositol biosynthesis] BioCyc
BioCyc Pathway Image PWY-2301 BioCyc
Ensembl Genes ENSRNOG00000019741 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026821 ENTREZGENE
  ENSRNOT00000026821.6 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7113337 IMAGE-MGC_LOAD
InterPro Myo-inos-1-P_Synthase UniProtKB/Swiss-Prot
  Myo-inos-1-P_Synthase_GAPDH UniProtKB/Swiss-Prot
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:290651 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93930 IMAGE-MGC_LOAD
NCBI Gene 290651 ENTREZGENE
PANTHER PTHR11510 UniProtKB/Swiss-Prot
Pfam Inos-1-P_synth UniProtKB/Swiss-Prot
  NAD_binding_5 UniProtKB/Swiss-Prot
PhenoGen Isyna1 PhenoGen
PIRSF Myoinos-ppht_syn UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019741 RatGTEx
Superfamily-SCOP Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain UniProtKB/Swiss-Prot
  SSF51735 UniProtKB/Swiss-Prot
UniProt A0ABK0L3F4_RAT UniProtKB/TrEMBL
  A6KA27 ENTREZGENE, UniProtKB/TrEMBL
  INO1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-30 Isyna1  inositol-3-phosphate synthase 1  Isyna1  myo-inositol 1-phosphate synthase A1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Isyna1  myo-inositol 1-phosphate synthase A1  LOC290651  similar to myo-inositol 1-phosphate synthase A1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 LOC290651  similar to myo-inositol 1-phosphate synthase A1      Symbol and Name status set to provisional 70820 PROVISIONAL