Atl1 (atlastin GTPase 1) - Rat Genome Database

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Gene: Atl1 (atlastin GTPase 1) Rattus norvegicus
Analyze
Symbol: Atl1
Name: atlastin GTPase 1
RGD ID: 1359232
Description: Enables GTP binding activity and GTPase activity. Involved in axonogenesis. Located in Golgi cis cisterna membrane; Golgi membrane; and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hereditary sensory neuropathy type 1D and hereditary spastic paraplegia 3A. Orthologous to human ATL1 (atlastin GTPase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aldehydo-D-glucose; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: atlastin-1; atlastin-like; LOC362750; MGC109404; spastic paraplegia 3A homolog; spastic paraplegia 3A homolog (human); Spg3a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8694,113,149 - 94,210,955 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl694,112,877 - 94,211,219 (+)EnsemblGRCr8
mRatBN7.2688,377,168 - 88,475,242 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,377,239 - 88,475,204 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx688,776,280 - 88,874,678 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0689,075,744 - 89,174,141 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0688,515,269 - 88,613,657 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,229,764 - 92,370,428 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,229,686 - 92,370,421 (+)Ensemblrn6Rnor6.0
Rnor_5.06101,678,899 - 101,819,542 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4691,979,260 - 92,077,664 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera686,872,333 - 86,970,392 (+)NCBICelera
RGSC_v3.1691,982,715 - 92,081,117 (+)NCBI
Cytogenetic Map6q24NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A class of dynamin-like GTPases involved in the generation of the tubular ER network. Hu J, etal., Cell. 2009 Aug 7;138(3):549-61. doi: 10.1016/j.cell.2009.05.025.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion. Yamamoto Y, etal., Biochem J. 2014 Feb 15;458(1):69-79. doi: 10.1042/BJ20131186.
9. SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development. Zhu PP, etal., Hum Mol Genet. 2006 Apr 15;15(8):1343-53. Epub 2006 Mar 14.
10. Cellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastin. Zhu PP, etal., J Biol Chem 2003 Dec 5;278(49):49063-71. Epub 2003 Sep 23.
Additional References at PubMed
PMID:12477932   PMID:20816793   PMID:21220294   PMID:21368113   PMID:22802620   PMID:22984613   PMID:23079343   PMID:23334294   PMID:24668814   PMID:27619977   PMID:29476059   PMID:30053369  


Genomics

Comparative Map Data
Atl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8694,113,149 - 94,210,955 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl694,112,877 - 94,211,219 (+)EnsemblGRCr8
mRatBN7.2688,377,168 - 88,475,242 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,377,239 - 88,475,204 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx688,776,280 - 88,874,678 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0689,075,744 - 89,174,141 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0688,515,269 - 88,613,657 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,229,764 - 92,370,428 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,229,686 - 92,370,421 (+)Ensemblrn6Rnor6.0
Rnor_5.06101,678,899 - 101,819,542 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4691,979,260 - 92,077,664 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera686,872,333 - 86,970,392 (+)NCBICelera
RGSC_v3.1691,982,715 - 92,081,117 (+)NCBI
Cytogenetic Map6q24NCBI
ATL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381450,533,082 - 50,633,068 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1450,532,509 - 50,634,017 (+)Ensemblhg38GRCh38
GRCh371450,999,800 - 51,099,786 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361450,096,500 - 50,169,141 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341450,096,513 - 50,169,532NCBI
Celera1430,866,848 - 30,966,813 (+)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1431,125,093 - 31,225,360 (+)NCBIHuRef
CHM1_11450,938,361 - 51,038,328 (+)NCBICHM1_1
T2T-CHM13v2.01444,738,771 - 44,839,213 (+)NCBIT2T-CHM13v2.0
Atl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391269,939,879 - 70,010,859 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1269,939,388 - 70,013,191 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381269,893,105 - 69,964,085 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1269,892,614 - 69,966,417 (+)Ensemblmm10GRCm38
MGSCv371270,994,092 - 71,065,072 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361270,811,874 - 70,882,636 (+)NCBIMGSCv36mm8
Celera1270,995,246 - 71,065,809 (+)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1228.94NCBI
Atl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540912,222,591 - 12,301,990 (-)Ensembl
ChiLan1.0NW_00495540912,222,591 - 12,301,990 (-)NCBIChiLan1.0ChiLan1.0
ATL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21551,671,566 - 51,771,723 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11450,888,068 - 50,988,225 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01431,122,551 - 31,222,537 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11449,452,923 - 49,524,726 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1449,476,733 - 49,524,392 (+)EnsemblpanPan2panpan1.1
ATL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1826,959,697 - 27,034,190 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl826,959,749 - 27,120,114 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha826,713,517 - 26,787,530 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0827,137,404 - 27,211,811 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl827,137,277 - 27,298,300 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1826,792,383 - 26,867,330 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0826,866,362 - 26,940,439 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0827,183,761 - 27,284,853 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Atl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864059,138,464 - 59,207,351 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649514,984,336 - 15,040,597 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649514,984,761 - 15,053,188 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1180,299,256 - 180,405,837 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11180,299,434 - 180,407,003 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21200,606,921 - 200,696,179 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12427,631,488 - 27,709,669 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2427,631,632 - 27,708,962 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605315,920,966 - 16,020,240 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473118,283,234 - 18,362,693 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473118,283,372 - 18,362,644 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Atl1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1783,563,577 - 83,654,677 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Atl1
491 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:52
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000046085
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
AI170938  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2688,446,012 - 88,446,111 (+)MAPPERmRatBN7.2
Rnor_6.0692,341,471 - 92,341,569NCBIRnor6.0
Rnor_5.06101,790,585 - 101,790,683UniSTSRnor5.0
RGSC_v3.4692,048,708 - 92,048,806UniSTSRGSC3.4
Celera686,941,565 - 86,941,663UniSTS
RH 3.4 Map6631.8UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 83 59 6 346 183 11 143 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000046085   ⟹   ENSRNOP00000041993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,112,877 - 94,210,946 (+)Ensembl
mRatBN7.2 Ensembl688,377,239 - 88,474,971 (+)Ensembl
Rnor_6.0 Ensembl692,229,686 - 92,370,421 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116837   ⟹   ENSRNOP00000084485
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,113,007 - 94,211,219 (+)Ensembl
mRatBN7.2 Ensembl688,377,239 - 88,475,204 (+)Ensembl
RefSeq Acc Id: NM_001009831   ⟹   NP_001009831
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8694,113,224 - 94,210,950 (+)NCBI
mRatBN7.2688,377,239 - 88,474,971 (+)NCBI
Rnor_6.0692,229,785 - 92,370,427 (+)NCBI
Rnor_5.06101,678,899 - 101,819,542 (+)NCBI
RGSC_v3.4691,979,260 - 92,077,664 (+)RGD
Celera686,872,333 - 86,970,392 (+)RGD
Sequence:
RefSeq Acc Id: XM_017594227   ⟹   XP_017449716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8694,113,149 - 94,210,955 (+)NCBI
mRatBN7.2688,377,168 - 88,475,242 (+)NCBI
Rnor_6.0692,229,764 - 92,370,428 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001009831 (Get FASTA)   NCBI Sequence Viewer  
  XP_017449716 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH92645 (Get FASTA)   NCBI Sequence Viewer  
  AAS89975 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000041993
  ENSRNOP00000041993.4
  ENSRNOP00000084485
GenBank Protein Q6PST4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009831   ⟸   NM_001009831
- UniProtKB: Q6PST4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017449716   ⟸   XM_017594227
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GAH6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000041993   ⟸   ENSRNOT00000046085
Ensembl Acc Id: ENSRNOP00000084485   ⟸   ENSRNOT00000116837
Protein Domains
GB1/RHD3-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6PST4-F1-model_v2 AlphaFold Q6PST4 1-558 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694641
Promoter ID:EPDNEW_R5164
Type:single initiation site
Name:Atl1_1
Description:atlastin GTPase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0692,229,612 - 92,229,672EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359232 AgrOrtholog
BioCyc Gene G2FUF-37220 BioCyc
Ensembl Genes ENSRNOG00000005063 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000046085 ENTREZGENE
  ENSRNOT00000046085.6 UniProtKB/Swiss-Prot
  ENSRNOT00000116837 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
  AHSP UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7318365 IMAGE-MGC_LOAD
InterPro G_GB1_RHD3_dom UniProtKB/Swiss-Prot
  Guanylate-bd_C_sf UniProtKB/Swiss-Prot
  Guanylate-bd_N UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:362750 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109404 IMAGE-MGC_LOAD
NCBI Gene 362750 ENTREZGENE
PANTHER GUANYLATE BINDING PROTEIN UniProtKB/Swiss-Prot
Pfam GBP UniProtKB/Swiss-Prot
PhenoGen Atl1 PhenoGen
PROSITE G_GB1_RHD3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005063 RatGTEx
Superfamily-SCOP SSF48340 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6GAH6 ENTREZGENE, UniProtKB/TrEMBL
  ATLA1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-11-06 Atl1  atlastin GTPase 1  Spg3a  spastic paraplegia 3A homolog (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Spg3a  spastic paraplegia 3A homolog (human)  LOC362750  atlastin-like  Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC362750  atlastin-like      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_disease mutation of the human homolog causes early onset hereditary spastic paraplegia SPG3A 1359760