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Gene: Fig4 (FIG4 phosphoinositide 5-phosphatase) Rattus norvegicus

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Symbol:

Fig4

Name:

FIG4 phosphoinositide 5-phosphatase

RGD ID:

1311375

Description:

Enables phosphatidylinositol bisphosphate phosphatase activity; phosphatidylinositol-3-phosphate phosphatase activity; and phosphatidylinositol-4-phosphate phosphatase activity. Involved in positive regulation of neuron projection development. Located in recycling endosome. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4J; Yunis-Varon syndrome; amyotrophic lateral sclerosis type 11; and bilateral parasagittal parieto-occipital polymicrogyria. Orthologous to human FIG4 (FIG4 phosphoinositide 5-phosphatase); PARTICIPATES IN inositol metabolic pathway; phosphoinositide metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

FIG4 homolog (S. cerevisiae); FIG4 homolog, SAC1 lipid phosphatase domain containing; FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae); Kiaa0274; LOC309855; polyphosphoinositide phosphatase; RGD1311375; Sac domain-containing inositol phosphatase 3; Sac3; similar to RIKEN cDNA A530089I17

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FIG4 (FIG4 phosphoinositide 5-phosphatase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Fig4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fig4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FIG4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FIG4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fig4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FIG4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FIG4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fig4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Fig4 (FIG4 phosphoinositide 5-phosphatase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PTER (phosphotriesterase related)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	FIG4 (FIG4 phosphoinositide 5-phosphatase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Fig4 (FIG4 phosphoinositide 5-phosphatase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fig4b (FIG4 phosphoinositide 5-phosphatase b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Danio rerio (zebrafish):	fig4a (FIG4 phosphoinositide 5-phosphatase a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fig4a (FIG4 phosphoinositide 5-phosphatase a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fig4a (FIG4 phosphoinositide 5-phosphatase a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Danio rerio (zebrafish):	fig4a (FIG4 phosphoinositide 5-phosphatase a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Danio rerio (zebrafish):	fig4a (FIG4 phosphoinositide 5-phosphatase a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fig4a (FIG4 phosphoinositide 5-phosphatase a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	FIG4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C34B7.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	FIG4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fig4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	46,183,225 - 46,306,686 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	46,183,225 - 46,306,477 (-)	Ensembl				GRCr8
mRatBN7.2	20	44,600,603 - 44,724,047 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	44,600,603 - 44,723,844 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	46,388,086 - 46,511,436 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	46,047,227 - 46,170,581 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	46,772,600 - 46,893,206 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	45,922,806 - 46,044,754 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	45,922,806 - 46,044,738 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	47,625,556 - 47,747,494 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	45,123,352 - 45,248,795 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	45,399,685 - 45,522,856 (-)	NCBI		Celera
RGSC_v3.1	20	45,146,775 - 45,222,780 (-)	NCBI
Cytogenetic Map	20	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis (ISO)

amyotrophic lateral sclerosis type 1 (ISO)

amyotrophic lateral sclerosis type 11 (ISO)

autosomal dominant distal hereditary motor neuronopathy (ISO)

B-Cell Chronic Lymphocytic Leukemia (ISO)

bilateral parasagittal parieto-occipital polymicrogyria (ISO)

Charcot-Marie-Tooth disease (ISO)

Charcot-Marie-Tooth disease type 1 (ISO)

Charcot-Marie-Tooth disease type 4 (ISO)

Charcot-Marie-Tooth disease type 4J (ISO,ISS)

Desbuquois dysplasia (ISO)

Failure to Thrive (ISO)

genetic disease (ISO)

Yunis-Varon syndrome (ISO,ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (EXP)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3',5'-cyclic AMP (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antimycin A (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

butanal (ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

chrysene (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

deguelin (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

nickel atom (ISO)

ozone (ISO)

paracetamol (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tebufenpyrad (ISO)

tetrachloromethane (EXP)

tetraphene (ISO)

thioacetamide (EXP)

topotecan (ISO)

trichostatin A (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process (IEA,ISO)

locomotory behavior (ISO)

myelin assembly (ISO)

negative regulation of myelination (ISO)

neuron development (ISO)

phosphatidylinositol dephosphorylation (IEA)

phosphatidylinositol metabolic process (ISO)

phosphatidylinositol-3-phosphate biosynthetic process (IEA)

pigmentation (ISO)

positive regulation of neuron projection development (IMP)

vacuole organization (ISO)

Cellular Component

endomembrane system (IEA)

endosome membrane (IEA,ISO)

recycling endosome (IDA)

Molecular Function

hydrolase activity (IEA)

phosphatase activity (IEA)

phosphatidylinositol bisphosphate phosphatase activity (IDA)

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity (IEA)

phosphatidylinositol-3-phosphate phosphatase activity (IDA)

phosphatidylinositol-4-phosphate phosphatase activity (IDA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

inositol metabolic pathway (ISO)

phosphoinositide metabolic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	rSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cells.	Yuan Y, etal., Cell Res. 2007 Nov;17(11):919-32.

Additional References at PubMed

PMID:17556371	PMID:17572665	PMID:22028665

Genomics

Comparative Map Data

Fig4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	46,183,225 - 46,306,686 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	46,183,225 - 46,306,477 (-)	Ensembl				GRCr8
mRatBN7.2	20	44,600,603 - 44,724,047 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	44,600,603 - 44,723,844 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	46,388,086 - 46,511,436 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	46,047,227 - 46,170,581 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	46,772,600 - 46,893,206 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	45,922,806 - 46,044,754 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	45,922,806 - 46,044,738 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	47,625,556 - 47,747,494 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	45,123,352 - 45,248,795 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	45,399,685 - 45,522,856 (-)	NCBI		Celera
RGSC_v3.1	20	45,146,775 - 45,222,780 (-)	NCBI
Cytogenetic Map	20	q12	NCBI

FIG4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	109,691,296 - 109,825,426 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	109,690,609 - 109,878,098 (+)	Ensembl			hg38	GRCh38
GRCh37	6	110,012,499 - 110,146,629 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	110,119,161 - 110,253,327 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	110,119,160 - 110,253,327	NCBI
Celera	6	110,759,045 - 110,893,292 (+)	NCBI		Celera
Cytogenetic Map	6	q21	NCBI
HuRef	6	107,578,606 - 107,713,071 (+)	NCBI		HuRef
CHM1_1	6	110,275,404 - 110,409,874 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	110,869,350 - 111,003,788 (+)	NCBI		T2T-CHM13v2.0

Fig4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	41,064,168 - 41,179,237 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	41,064,168 - 41,179,256 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	41,188,172 - 41,303,241 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	41,188,172 - 41,303,260 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	40,907,978 - 41,023,047 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	40,876,587 - 40,991,656 (-)	NCBI		MGSCv36	mm8
Celera	10	42,083,412 - 42,197,996 (-)	NCBI		Celera
Cytogenetic Map	10	B1	NCBI
cM Map	10	22.08	NCBI

Fig4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	3,135,752 - 3,218,052 (-)	Ensembl
ChiLan1.0	NW_004955411	3,135,752 - 3,217,891 (-)	NCBI	ChiLan1.0	ChiLan1.0

FIG4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	129,701,209 - 129,836,807 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	127,589,237 - 127,723,686 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	107,495,637 - 107,631,201 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	111,539,937 - 111,673,894 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	111,539,937 - 111,673,894 (+)	Ensembl			panPan2	panpan1.1

FIG4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	66,508,801 - 66,632,830 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	66,509,431 - 66,632,822 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	66,329,148 - 66,452,527 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	67,393,792 - 67,518,028 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	67,394,350 - 67,518,026 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	66,742,283 - 66,865,882 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	66,591,834 - 66,714,914 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	66,863,026 - 66,986,428 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fig4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	101,462,042 - 101,567,353 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936564	5,736,873 - 5,842,722 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936564	5,736,908 - 5,842,210 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FIG4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	75,694,151 - 75,847,528 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	75,694,151 - 75,847,021 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	85,452,466 - 85,539,950 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	1	84,995,954 - 85,027,999 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FIG4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	64,054,000 - 64,186,800 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	64,054,002 - 64,186,714 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	36,346,233 - 36,489,346 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fig4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624850	29,362 - 156,346 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fig4
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	40,904,401 - 41,019,416 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fig4
987 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	52
Count of miRNA genes:	43
Interacting mature miRNAs:	51
Transcripts:	ENSRNOT00000000343
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	4189476	49189476	Rat
2303587	Bw93	Body weight QTL 93	13		body mass (VT:0001259)	body weight (CMO:0000012)	20	26689362	56021148	Rat
1598858	Cm61	Cardiac mass QTL 61	3.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	20	8216359	53216359	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1533083	46533083	Rat
1331747	Hrtrt16	Heart rate QTL 16	3.163		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	20	26792353	56021148	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	12243242	49189476	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	20745585	56021148	Rat
2303578	Gluco50	Glucose level QTL 50	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	20	26689362	56021148	Rat
1598869	Memor6	Memory QTL 6	3.1		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	20	26689362	56021148	Rat
1598870	Bp289	Blood pressure QTL 289	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	8216359	53216359	Rat
2300188	Bmd68	Bone mineral density QTL 68	6.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	20	26689362	56021148	Rat

Markers in Region

RH129633

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	44,600,606 - 44,600,793 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	45,922,810 - 45,922,996	NCBI	Rnor6.0
Rnor_5.0	20	47,625,560 - 47,625,746	UniSTS	Rnor5.0
RGSC_v3.4	20	45,123,356 - 45,123,542	UniSTS	RGSC3.4
Celera	20	45,399,689 - 45,399,875	UniSTS
RH 3.4 Map	20	471.3	UniSTS
Cytogenetic Map	20	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001047096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ666853	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000000343 ⟹ ENSRNOP00000000343

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	46,183,225 - 46,306,477 (-)	Ensembl
mRatBN7.2 Ensembl	20	44,600,603 - 44,723,844 (-)	Ensembl
Rnor_6.0 Ensembl	20	45,922,806 - 46,044,738 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101588 ⟹ ENSRNOP00000091577

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	46,183,225 - 46,306,477 (-)	Ensembl
mRatBN7.2 Ensembl	20	44,600,603 - 44,723,844 (-)	Ensembl

RefSeq Acc Id:

NM_001047096 ⟹ NP_001040561

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	46,183,225 - 46,306,477 (-)	NCBI
mRatBN7.2	20	44,600,603 - 44,723,844 (-)	NCBI
Rnor_6.0	20	45,922,806 - 46,044,536 (-)	NCBI
Rnor_5.0	20	47,625,556 - 47,747,494 (-)	NCBI
RGSC_v3.4	20	45,123,352 - 45,248,795 (-)	RGD
Celera	20	45,399,685 - 45,522,856 (-)	RGD

Sequence:

show sequence

GCCATGCCCACGGCCGCTGCCCCCATCATCAGTTCGGTCCAGAAGCTGGTGCTCTATGAGACTA
GAGCTAGATACTTTCTAGTCGGGAGCAATCATGCGGAAACAAAGTTCCGAGTCCTGAAGATTGA
TAGAACAGAACCAAAGGATTTGGTGGTGATTGACGATAGGCACGTGTACACGCAACAGGAAGTG
CGGGAACTTCTTGGCCGCCTGGATCTGGGAAACAGAACAAAGCTGAGCCAGAAAGGATCCTCCG
GGTTGTTTCGAGCCGTCTCCGCGTTTGGTGTCGTAGGTTTTGTCAGGTTCTTAGAAGGCTACTA
TATCGTATTAATAACTAAGCGGAGGAAGATGGCGGATATCGGAGGCCATGCAATATATAAGATT
GAAGATACAAGTATGATTTATATCCCCAATGACTCTGTTCGGATTACTCACCCCGACGAAGCTA
GGTACCTAAGGATATTCCAAAATGTGGATCTGTCCAGCAATTTTTACTTTAGTTACAGCTATGA
TCTGTCCCACTCCCTTCAGTACAATCTTACCGTCCTGCGAATGCCCCTGGAGATGTTAAAGTCG
GAAACATCCAAGACCTGCCAGGAGAGCTTCGACATCTTTGAAGATGAAGGGTTAACTACGCAGG
GCGGCAGTGGCGTATTTGGGATCTCTAGTGAGCCTTACATGAAGTATGTCTGGAACGGCGAACT
TCTGGATATAATTAAAAACAGCGTGCATCGCGACTGGCTACTGTATATCATTCATGGGTTCTGC
GGGCAGTCAAAGCTTCTGATCTATGGACGACCAGTGTATGTGACCCTAATAGCCAGAAGATCCA
GTAGGTTTGCTGGGACGCGCTTTCTCAAGAGAGGTGCAAACTGTGAGGGAGATGTTGCCAACGA
GGTGGAGACGGAGCAGATCCTCTGTGATGCCTCGGTGATGTCTTTTACCGCAGGCAGTTACTCT
TCTTACGTACAAGTCAGAGGCTCTGTTCCCTTATTCTGGTCCCAAGACATCTCAACCATGATGC
CGAAACCACCCATTACACTGGACCAGGCAGATCCCTTCGCACACATAGCCGCTCTTCACTTTGA
CCAGATGCTGCAGAGGTTTGGCTCCCCCATCATCATCCTGAACTTAGTGAAGGAGAGAGAGAAG
AGAAAGCACGAAAGGATTCTGAGCGAGGAGCTGGTGGCCGCGGTTACTTACCTTAACCAGTTCC
TGCCCCCGGAGCACAGCATTGTATACATTCCCTGGGATATGGCCAAGTACACCAAGAGTAAGCT
GTGTAACGTTCTCGATCGTCTGAACGTGATTGCAGAAAGCGTGGTAAAGAAGACAGGCTTCTTC
GTCAACCGCCCTGATTCTTACTGCAGCGTTTTACGGCCAGATGAGAAGTGGAACGAACTAGGAG
GTCGTGTGATTCCCACTGGTCGGCTCCAGACCGGCATCCTTCGAACCAACTGCGTGGACTGTTT
GGATCGTACCAACACGGCGCAGTTCATGGTGGGCAAGTGCGCCCTGGCTTACCAGCTGTACTCC
TTAGGGCTGATTGACAAGCCCAACCTGCAGTTCGATACGGACGCAGTGAGGTTATTTGAGGAAC
TCTATGAAGACCATGGAGACACCCTTTCCCTGCAGTACGGAGGCTCTCAGCTGGTTCATCGGGT
GAAGACCTACAGAAAGATAGCGCCGTGGACCCAGCACTCCAAGGACATCATGCAGACGCTGTCT
CGGTACTACAGCAATGCCTTTTCAGATGCGGACAGACAAGATTCCATCAACCTGTTCTTGGGTG
TTTTCCACCCCACAGAAGGGAAACCTCATCTCTGGGAACTTCCCACGGACTTTTACCTGCATCA
CAAAAACACCATGAGCCTTTTACCCCCCAAAAGGAGTTATACTCACTGGTGGACACCAGAGGTG
GTGAAGCATTTGCCGCTGCCTTACGACGAAGTTATCTGTGCTGCAAACTTAAAGAAGTTGACGG
TGAAGAAGTTTCACAGATGGGAAGAGGAGATTGATATTCACAATGAGTTCTTCCGGCCGTATGA
ATTGAGTAGTTTTGATGACACCTTTTGCCTGGCCATGACAAGTTCAGCACGTGATTTTATGCCT
AAAACTATTGGCATTGACCCAAGTCCATTCACCGTGCGAAAACCAGACGAAACCGGGAAATCTG
TACTGGGGAACAAAAGCAACAGAGAGGAGGCCGTCCTGCAACGGAAAACGGCAGCCAGCGCCCC
GCCACCCCCCAGCGAGGAGGCCGTGTCCAGCAGCTCCGAGGACGACTCTGGTACTGACCGGGAA
GACGAAGGTTCCATCTCGCAGCGATCCACTCCTGTGAAGATGACTGACACCGGAGACAGCGCCA
AAGTGACTGAGAGTGTGGCCCAACCCATGAAGGAAGTGTACGGAGTTAGCCTCTCACGTAGCCT
GTCCGAGGAGGATCACTCCATTTATGCCAGGTTTGTTCAACTGGGGCAGAGTCAGCATAGACAG
GACTGGAGCAGCCCGCAGATGTGTGCCCGGTGCTCAGACGGAGTTATCAAACTAACCCCCATCT
CAGCTTTCTCGCAAGACAACATTTATGAAGTTCAGCCCCCGAGAGTAGACAGAAAGTCCACAGA
GATCTTCCAGGCCCACATCCAGGCCAGCCAAGGTATCATGCAGCCCCTTGGCAAAGAGGACACT
GCCATATACCGGGAGTACATCAGAAACCGCTACTTATAACGACGGCCCCGAGGACAGTGGGGTT
AGCTTCTTTTCAGTGTTGTCTGCGAGAAGGAATTCCCAGGACCTGGAGATGCAGCTCAGTAGTA
AAGGACACGTACTTCCAGAGGCTCGGAACCTGGTCCCCAGCACCCGTATCACAACCTTCGGTAA
CTCCAGCTACAAAGAATCCAATGTTGTCTTCTGTATTTTGTACACACCTATACTCAAGTGGGTG
CCTGTGTGTGTACACCCATGCACAGGCGAACATGCATATGCGTGCACATGCTTGCACACACACA
CACACACACACTAAAAATACTAGAAGTGAAATCCTTAATAACCAATTCATCCAAATCATGGATC
TGAAGCTTTTCACCCCTTTGAACCATGCAAATTACTAACTACAGGTAATAAAGAAGTGTCTGCC
TCTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006256540 ⟹ XP_006256602

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	46,183,225 - 46,285,080 (-)	NCBI
mRatBN7.2	20	44,600,603 - 44,701,510 (-)	NCBI
Rnor_6.0	20	45,922,806 - 46,023,564 (-)	NCBI
Rnor_5.0	20	47,625,556 - 47,747,494 (-)	NCBI

Sequence:

show sequence

TTCAGGCCTGCCCTCGAGCCCCTCATGCAGGGGCTGCAGTGTGTGTGTGTGCTTGGAGGAGGCG
AAATCGCAGCTCTTAGTGGGACAGTGCCTGGGGTTCCTCCTGCTATATTTTTGTCACATTATTT
TAATCACACCCCTCACTTTTCTAATTACCTTCTAGCAATTACTGGTGCTGAGAAATTAGGCAGA
TTATACTTTGCCCTTCAGTTTGATTTGTTTCTGAGAGCACTCATTCCCCTAGGAAGACAAGGAA
GATCTTTTCCTAATCCACTGACCTTTTAAGGATTCAGTGTGACTAACATTGCTCTACCAGGGTG
TGTATCACTGTGCTCAGTACAGACGTTTGAAGGCTTGCCGTACACTAAGAAACGCTGAACAAGT
GCTCTGCAGGTCCTGAGTTGTGTAGACTCAGGAGTGCAAAGGCTTCCTTCATGCAGCACAAGAG
CGTGAGGCTGTTAGTCAGAAGTGCCACGTAGGGTAGTGGTGCTGACCGGTTAATCTTTGGCAAA
CCAAATGAGGGCACTTATTCTTTGTGTTGAATTTCCTAGATAAATATTTCTGAATGCACATAGG
TTCCAGTTTTGTGAAACACAGTAGTAGTCATAGTTTGGAATAGTTTTCAGTAAATCTTTGCAGA
AGGATGTCCCGTGTTCTAACGATTGTGGATAGATTCACTATTAGGGTTTTTCATGTCCCTGGAT
CTGCCCGGAAGCTTCTATTAATATAGCGGACTGTTCTTGGCTTTACATGGTACCTGGGCTGATT
GGTCAGGGAGACCCTGGAGGAGCTGACAGTTATGGGCCACCTCATACAAATGCACGTCTAGTTG
AGGGTTTGCGTCTCAGTTTAAGGGGTTCACAAACTTACTGAAGTGGGCGGGTCCCTTTGATCTC
GGAATCTCAGTTCACACTCGAGCTTTGACCTCATTTTCTTTTTTTTTTTTTTTTTTTTGGTTCT
TTTTTTTTCGGAGCTGGGGACCGAACCCAGGGCCTTGAGCTTCCTAGCACGTGTACACGCAACA
GGAAGTGCGGGAACTTCTTGGCCGCCTGGATCTGGGAAACAGAACAAAGCTGAGCCAGAAAGGA
TCCTCCGGGTTGTTTCGAGCCGTCTCCGCGTTTGGTGTCGTAGGTTTTGTCAGGTTCTTAGAAG
GCTACTATATCGTATTAATAACTAAGCGGAGGAAGATGGCGGATATCGGAGGCCATGCAATATA
TAAGATTGAAGATACAAGTATGATTTATATCCCCAATGACTCTGTTCGGATTACTCACCCCGAC
GAAGCTAGGTACCTAAGGATATTCCAAAATGTGGATCTGTCCAGCAATTTTTACTTTAGTTACA
GCTATGATCTGTCCCACTCCCTTCAGTACAATCTTACCGTCCTGCGAATGCCCCTGGAGATGTT
AAAGTCGGAAACATCCAAGACCTGCCAGGAGAGCTTCGACATCTTTGAAGATGAAGGGTTAACT
ACGCAGGGCGGCAGTGGCGTATTTGGGATCTCTAGTGAGCCTTACATGAAGTATGTCTGGAACG
GCGAACTTCTGGATATAATTAAAAACAGCGTGCATCGCGACTGGCTACTGTATATCATTCATGG
GTTCTGCGGGCAGTCAAAGCTTCTGATCTATGGACGACCAGTGTATGTGACCCTAATAGCCAGA
AGATCCAGTAGGTTTGCTGGGACGCGCTTTCTCAAGAGAGGTGCAAACTGTGAGGGAGATGTTG
CCAACGAGGTGGAGACGGAGCAGATCCTCTGTGATGCCTCGGTGATGTCTTTTACCGCAGGCAG
TTACTCTTCTTACGTACAAGTCAGAGGCTCTGTTCCCTTATTCTGGTCCCAAGACATCTCAACC
ATGATGCCGAAACCACCCATTACACTGGACCAGGCAGATCCCTTCGCACACATAGCCGCTCTTC
ACTTTGACCAGATGCTGCAGAGGTTTGGCTCCCCCATCATCATCCTGAACTTAGTGAAGGAGAG
AGAGAAGAGAAAGCACGAAAGGATTCTGAGCGAGGAGCTGGTGGCCGCGGTTACTTACCTTAAC
CAGTTCCTGCCCCCGGAGCACAGCATTGTATACATTCCCTGGGATATGGCCAAGTACACCAAGA
GTAAGCTGTGTAACGTTCTCGATCGTCTGAACGTGATTGCAGAAAGCGTGGTAAAGAAGACAGG
CTTCTTCGTCAACCGCCCTGATTCTTACTGCAGCGTTTTACGGCCAGATGAGAAGTGGAACGAA
CTAGGAGGTCGTGTGATTCCCACTGGTCGGCTCCAGACCGGCATCCTTCGAACCAACTGCGTGG
ACTGTTTGGATCGTACCAACACGGCGCAGTTCATGGTGGGCAAGTGCGCCCTGGCTTACCAGCT
GTACTCCTTAGGGCTGATTGACAAGCCCAACCTGCAGTTCGATACGGACGCAGTGAGGTTATTT
GAGGAACTCTATGAAGACCATGGAGACACCCTTTCCCTGCAGTACGGAGGCTCTCAGCTGGTTC
ATCGGGTGAAGACCTACAGAAAGATAGCGCCGTGGACCCAGCACTCCAAGGACATCATGCAGAC
GCTGTCTCGGTACTACAGCAATGCCTTTTCAGATGCGGACAGACAAGATTCCATCAACCTGTTC
TTGGGTGTTTTCCACCCCACAGAAGGGAAACCTCATCTCTGGGAACTTCCCACGGACTTTTACC
TGCATCACAAAAACACCATGAGCCTTTTACCCCCCAAAAGGAGTTATACTCACTGGTGGACACC
AGAGGTGGTGAAGCATTTGCCGCTGCCTTACGACGAAGTTATCTGTGCTGCAAACTTAAAGAAG
TTGACGGTGAAGAAGTTTCACAGATGGGAAGAGGAGATTGATATTCACAATGAGTTCTTCCGGC
CGTATGAATTGAGTAGTTTTGATGACACCTTTTGCCTGGCCATGACAAGTTCAGCACGTGATTT
TATGCCTAAAACTATTGGCATTGACCCAAGTCCATTCACCGTGCGAAAACCAGACGAAACCGGG
AAATCTGTACTGGGGAACAAAAGCAACAGAGAGGAGGCCGTCCTGCAACGGAAAACGGCAGCCA
GCGCCCCGCCACCCCCCAGCGAGGAGGCCGTGTCCAGCAGCTCCGAGGACGACTCTGGTACTGA
CCGGGAAGACGAAGGTTCCATCTCGCAGCGATCCACTCCTGTGAAGATGACTGACACCGGAGAC
AGCGCCAAAGTGACTGAGAGTGTGGCCCAACCCATGAAGGAAGTGTACGGAGTTAGCCTCTCAC
GTAGCCTGTCCGAGGAGGATCACTCCATTTATGCCAGGTTTGTTCAACTGGGGCAGAGTCAGCA
TAGACAGGACTGGAGCAGCCCGCAGATGTGTGCCCGGTGCTCAGACGGAGTTATCAAACTAACC
CCCATCTCAGCTTTCTCGCAAGACAACATTTATGAAGTTCAGCCCCCGAGAGTAGACAGAAAGT
CCACAGAGATCTTCCAGGCCCACATCCAGGCCAGCCAAGGTATCATGCAGCCCCTTGGCAAAGA
GGACACTGCCATATACCGGGAGTACATCAGAAACCGCTACTTATAACGACGGCCCCGAGGACAG
TGGGGTTAGCTTCTTTTCAGTGTTGTCTGCGAGAAGGAATTCCCAGGACCTGGAGATGCAGCTC
AGTAGTAAAGGACACGTACTTCCAGAGGCTCGGAACCTGGTCCCCAGCACCCGTATCACAACCT
TCGGTAACTCCAGCTACAAAGAATCCAATGTTGTCTTCTGTATTTTGTACACACCTATACTCAA
GTGGGTGCCTGTGTGTGTACACCCATGCACAGGCGAACATGCATATGCGTGCACATGCTTGCAC
ACACACACACACACACACTAAAAATACTAGAAGTGAAATCCTTAATAACCAATTCATCCAAATC
ATGGATCTGAAGCTTTTCACCCCTTTGAACCATGCAAATTACTAACTACAGGTAATAAAGAAGT
GTCTGCCTCTG

hide sequence

RefSeq Acc Id:

XM_006256541 ⟹ XP_006256603

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	46,183,225 - 46,306,671 (-)	NCBI
mRatBN7.2	20	44,600,603 - 44,724,043 (-)	NCBI
Rnor_6.0	20	45,922,806 - 46,044,549 (-)	NCBI
Rnor_5.0	20	47,625,556 - 47,747,494 (-)	NCBI

Sequence:

show sequence

TCCATTGGCTGGAGCCATGCCCACGGCCGCTGCCCCCATCATCAGTTCGGTCCAGAAGCTGGTG
CTCTATGAGACTAGAGCTGTTTTGTCAGGTTCTTAGAAGGCTACTATATCGTATTAATAACTAA
GCGGAGGAAGATGGCGGATATCGGAGGCCATGCAATATATAAGATTGAAGATACAAGTATGATT
TATATCCCCAATGACTCTGTTCGGATTACTCACCCCGACGAAGCTAGGTACCTAAGGATATTCC
AAAATGTGGATCTGTCCAGCAATTTTTACTTTAGTTACAGCTATGATCTGTCCCACTCCCTTCA
GTACAATCTTACCGTCCTGCGAATGCCCCTGGAGATGTTAAAGTCGGAAACATCCAAGACCTGC
CAGGAGAGCTTCGACATCTTTGAAGATGAAGGGTTAACTACGCAGGGCGGCAGTGGCGTATTTG
GGATCTCTAGTGAGCCTTACATGAAGTATGTCTGGAACGGCGAACTTCTGGATATAATTAAAAA
CAGCGTGCATCGCGACTGGCTACTGTATATCATTCATGGGTTCTGCGGGCAGTCAAAGCTTCTG
ATCTATGGACGACCAGTGTATGTGACCCTAATAGCCAGAAGATCCAGTAGGTTTGCTGGGACGC
GCTTTCTCAAGAGAGGTGCAAACTGTGAGGGAGATGTTGCCAACGAGGTGGAGACGGAGCAGAT
CCTCTGTGATGCCTCGGTGATGTCTTTTACCGCAGGCAGTTACTCTTCTTACGTACAAGTCAGA
GGCTCTGTTCCCTTATTCTGGTCCCAAGACATCTCAACCATGATGCCGAAACCACCCATTACAC
TGGACCAGGCAGATCCCTTCGCACACATAGCCGCTCTTCACTTTGACCAGATGCTGCAGAGGTT
TGGCTCCCCCATCATCATCCTGAACTTAGTGAAGGAGAGAGAGAAGAGAAAGCACGAAAGGATT
CTGAGCGAGGAGCTGGTGGCCGCGGTTACTTACCTTAACCAGTTCCTGCCCCCGGAGCACAGCA
TTGTATACATTCCCTGGGATATGGCCAAGTACACCAAGAGTAAGCTGTGTAACGTTCTCGATCG
TCTGAACGTGATTGCAGAAAGCGTGGTAAAGAAGACAGGCTTCTTCGTCAACCGCCCTGATTCT
TACTGCAGCGTTTTACGGCCAGATGAGAAGTGGAACGAACTAGGAGGTCGTGTGATTCCCACTG
GTCGGCTCCAGACCGGCATCCTTCGAACCAACTGCGTGGACTGTTTGGATCGTACCAACACGGC
GCAGTTCATGGTGGGCAAGTGCGCCCTGGCTTACCAGCTGTACTCCTTAGGGCTGATTGACAAG
CCCAACCTGCAGTTCGATACGGACGCAGTGAGGTTATTTGAGGAACTCTATGAAGACCATGGAG
ACACCCTTTCCCTGCAGTACGGAGGCTCTCAGCTGGTTCATCGGGTGAAGACCTACAGAAAGAT
AGCGCCGTGGACCCAGCACTCCAAGGACATCATGCAGACGCTGTCTCGGTACTACAGCAATGCC
TTTTCAGATGCGGACAGACAAGATTCCATCAACCTGTTCTTGGGTGTTTTCCACCCCACAGAAG
GGAAACCTCATCTCTGGGAACTTCCCACGGACTTTTACCTGCATCACAAAAACACCATGAGCCT
TTTACCCCCCAAAAGGAGTTATACTCACTGGTGGACACCAGAGGTGGTGAAGCATTTGCCGCTG
CCTTACGACGAAGTTATCTGTGCTGCAAACTTAAAGAAGTTGACGGTGAAGAAGTTTCACAGAT
GGGAAGAGGAGATTGATATTCACAATGAGTTCTTCCGGCCGTATGAATTGAGTAGTTTTGATGA
CACCTTTTGCCTGGCCATGACAAGTTCAGCACGTGATTTTATGCCTAAAACTATTGGCATTGAC
CCAAGTCCATTCACCGTGCGAAAACCAGACGAAACCGGGAAATCTGTACTGGGGAACAAAAGCA
ACAGAGAGGAGGCCGTCCTGCAACGGAAAACGGCAGCCAGCGCCCCGCCACCCCCCAGCGAGGA
GGCCGTGTCCAGCAGCTCCGAGGACGACTCTGGTACTGACCGGGAAGACGAAGGTTCCATCTCG
CAGCGATCCACTCCTGTGAAGATGACTGACACCGGAGACAGCGCCAAAGTGACTGAGAGTGTGG
CCCAACCCATGAAGGAAGTGTACGGAGTTAGCCTCTCACGTAGCCTGTCCGAGGAGGATCACTC
CATTTATGCCAGGTTTGTTCAACTGGGGCAGAGTCAGCATAGACAGGACTGGAGCAGCCCGCAG
ATGTGTGCCCGGTGCTCAGACGGAGTTATCAAACTAACCCCCATCTCAGCTTTCTCGCAAGACA
ACATTTATGAAGTTCAGCCCCCGAGAGTAGACAGAAAGTCCACAGAGATCTTCCAGGCCCACAT
CCAGGCCAGCCAAGGTATCATGCAGCCCCTTGGCAAAGAGGACACTGCCATATACCGGGAGTAC
ATCAGAAACCGCTACTTATAACGACGGCCCCGAGGACAGTGGGGTTAGCTTCTTTTCAGTGTTG
TCTGCGAGAAGGAATTCCCAGGACCTGGAGATGCAGCTCAGTAGTAAAGGACACGTACTTCCAG
AGGCTCGGAACCTGGTCCCCAGCACCCGTATCACAACCTTCGGTAACTCCAGCTACAAAGAATC
CAATGTTGTCTTCTGTATTTTGTACACACCTATACTCAAGTGGGTGCCTGTGTGTGTACACCCA
TGCACAGGCGAACATGCATATGCGTGCACATGCTTGCACACACACACACACACACACTAAAAAT
ACTAGAAGTGAAATCCTTAATAACCAATTCATCCAAATCATGGATCTGAAGCTTTTCACCCCTT
TGAACCATGCAAATTACTAACTACAGGTAATAAAGAAGTGTCTGCCTCTG

hide sequence

RefSeq Acc Id:

XM_039098766 ⟹ XP_038954694

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	46,183,225 - 46,285,080 (-)	NCBI
mRatBN7.2	20	44,600,603 - 44,701,510 (-)	NCBI

RefSeq Acc Id:

XM_039098767 ⟹ XP_038954695

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	46,248,423 - 46,306,686 (-)	NCBI
mRatBN7.2	20	44,665,796 - 44,724,047 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001040561	(Get FASTA)	NCBI Sequence Viewer
	XP_006256602	(Get FASTA)	NCBI Sequence Viewer
	XP_006256603	(Get FASTA)	NCBI Sequence Viewer
	XP_038954694	(Get FASTA)	NCBI Sequence Viewer
	XP_038954695	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABG56230	(Get FASTA)	NCBI Sequence Viewer
	EDL83245	(Get FASTA)	NCBI Sequence Viewer
	EDL83246	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000000343
	ENSRNOP00000000343.2
	ENSRNOP00000091577.1

RefSeq Acc Id:

NP_001040561 ⟸ NM_001047096

- UniProtKB:

Q0Z843 (UniProtKB/TrEMBL), A6KTC8 (UniProtKB/TrEMBL), A0A8I6ADY9 (UniProtKB/TrEMBL), F7ESC7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPTAAAPIISSVQKLVLYETRARYFLVGSNHAETKFRVLKIDRTEPKDLVVIDDRHVYTQQEVR
ELLGRLDLGNRTKLSQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKIE
DTSMIYIPNDSVRITHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSE
TSKTCQESFDIFEDEGLTTQGGSGVFGISSEPYMKYVWNGELLDIIKNSVHRDWLLYIIHGFCG
QSKLLIYGRPVYVTLIARRSSRFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSS
YVQVRGSVPLFWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSPIIILNLVKEREKR
KHERILSEELVAAVTYLNQFLPPEHSIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFV
NRPDSYCSVLRPDEKWNELGGRVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSL
GLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSR
YYSNAFSDADRQDSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMSLLPPKRSYTHWWTPEVV
KHLPLPYDEVICAANLKKLTVKKFHRWEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPK
TIGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDRED
EGSISQRSTPVKMTDTGDSAKVTESVAQPMKEVYGVSLSRSLSEEDHSIYARFVQLGQSQHRQD
WSSPQMCARCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDTA
IYREYIRNRYL

hide sequence

RefSeq Acc Id:	XP_006256603 ⟸ XM_006256541
- Peptide Label:	isoform X1
- UniProtKB:	A6KTC9 (UniProtKB/TrEMBL), A0A8I6ADY9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADIGGHAIYKIEDTSMIYIPNDSVRITHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNL TVLRMPLEMLKSETSKTCQESFDIFEDEGLTTQGGSGVFGISSEPYMKYVWNGELLDIIKNSVH RDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSRFAGTRFLKRGANCEGDVANEVETEQILCD ASVMSFTAGSYSSYVQVRGSVPLFWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSP IIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHSIVYIPWDMAKYTKSKLCNVLDRLNV IAESVVKKTGFFVNRPDSYCSVLRPDEKWNELGGRVIPTGRLQTGILRTNCVDCLDRTNTAQFM VGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPW TQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMSLLPP KRSYTHWWTPEVVKHLPLPYDEVICAANLKKLTVKKFHRWEEEIDIHNEFFRPYELSSFDDTFC LAMTSSARDFMPKTIGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVS SSSEDDSGTDREDEGSISQRSTPVKMTDTGDSAKVTESVAQPMKEVYGVSLSRSLSEEDHSIYA RFVQLGQSQHRQDWSSPQMCARCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQAS QGIMQPLGKEDTAIYREYIRNRYL hide sequence

RefSeq Acc Id:	XP_006256602 ⟸ XM_006256540
- Peptide Label:	isoform X1
- UniProtKB:	A6KTC9 (UniProtKB/TrEMBL), A0A8I6ADY9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADIGGHAIYKIEDTSMIYIPNDSVRITHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNL TVLRMPLEMLKSETSKTCQESFDIFEDEGLTTQGGSGVFGISSEPYMKYVWNGELLDIIKNSVH RDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSRFAGTRFLKRGANCEGDVANEVETEQILCD ASVMSFTAGSYSSYVQVRGSVPLFWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSP IIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHSIVYIPWDMAKYTKSKLCNVLDRLNV IAESVVKKTGFFVNRPDSYCSVLRPDEKWNELGGRVIPTGRLQTGILRTNCVDCLDRTNTAQFM VGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPW TQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMSLLPP KRSYTHWWTPEVVKHLPLPYDEVICAANLKKLTVKKFHRWEEEIDIHNEFFRPYELSSFDDTFC LAMTSSARDFMPKTIGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVS SSSEDDSGTDREDEGSISQRSTPVKMTDTGDSAKVTESVAQPMKEVYGVSLSRSLSEEDHSIYA RFVQLGQSQHRQDWSSPQMCARCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQAS QGIMQPLGKEDTAIYREYIRNRYL hide sequence

Ensembl Acc Id:

ENSRNOP00000000343 ⟸ ENSRNOT00000000343

RefSeq Acc Id:	XP_038954694 ⟸ XM_039098766
- Peptide Label:	isoform X1
- UniProtKB:	A6KTC9 (UniProtKB/TrEMBL), A0A8I6ADY9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038954695 ⟸ XM_039098767
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000091577 ⟸ ENSRNOT00000101588

Protein Domains

SAC

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q0Z843-F1-model_v2	AlphaFold	Q0Z843	1-907	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701661

Promoter ID:

EPDNEW_R12184

Type:

initiation region

Name:

Fig4_1

Description:

FIG4 phosphoinositide 5-phosphatase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	46,044,727 - 46,044,787	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311375	AgrOrtholog
BioCyc Gene	G2FUF-3409	BioCyc
Ensembl Genes	ENSRNOG00000000312	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000343	ENTREZGENE
	ENSRNOT00000000343.6	UniProtKB/TrEMBL
	ENSRNOT00000101588.2	UniProtKB/TrEMBL
InterPro	Fig4-like	UniProtKB/TrEMBL
	Syja_N	UniProtKB/TrEMBL
KEGG Report	rno:309855	UniProtKB/TrEMBL
NCBI Gene	309855	ENTREZGENE
PANTHER	POLYPHOSPHOINOSITIDE PHOSPHATASE	UniProtKB/TrEMBL
	PTHR45738	UniProtKB/TrEMBL
Pfam	Syja_N	UniProtKB/TrEMBL
PhenoGen	Fig4	PhenoGen
PROSITE	SAC	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000312	RatGTEx
UniProt	A0A8I6ADY9	ENTREZGENE, UniProtKB/TrEMBL
	A6KTC8	ENTREZGENE, UniProtKB/TrEMBL
	A6KTC9	ENTREZGENE, UniProtKB/TrEMBL
	F7ESC7	ENTREZGENE, UniProtKB/TrEMBL
	Q0Z843	ENTREZGENE
UniProt Secondary	Q0Z843	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-08-06	Fig4	FIG4 phosphoinositide 5-phosphatase	Fig4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-02	Fig4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	Fig4	FIG4 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-27	Fig4	FIG4 homolog (S. cerevisiae)	RGD1311375_predicted	similar to RIKEN cDNA A530089I17 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1311375_predicted	similar to RIKEN cDNA A530089I17 (predicted)	LOC309855_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC309855_predicted	similar to RIKEN cDNA A530089I17 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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