Fndc1 (fibronectin type III domain containing 1) - Rat Genome Database

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Pathways
Gene: Fndc1 (fibronectin type III domain containing 1) Rattus norvegicus
Analyze
Symbol: Fndc1
Name: fibronectin type III domain containing 1
RGD ID: 1310640
Description: Acts upstream of or within several processes, including cellular response to hypoxia; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of protein phosphorylation. Located in cell-cell junction; mitochondrial membrane; and plasma membrane. Orthologous to human FNDC1 (fibronectin type III domain containing 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: activator of G-protein signaling 8; fibronectin type III domain-containing protein 1; LOC308099
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,686,856 - 49,769,263 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl149,686,856 - 49,769,263 (+)EnsemblGRCr8
mRatBN7.2147,281,839 - 47,364,247 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,281,844 - 47,364,259 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx147,851,601 - 47,912,467 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,832,549 - 53,893,699 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,927,067 - 47,987,956 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,605,211 - 47,687,499 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,605,262 - 47,687,504 (+)Ensemblrn6Rnor6.0
Rnor_5.0148,905,631 - 48,987,877 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4141,522,019 - 41,583,357 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera142,986,709 - 43,047,709 (+)NCBICelera
RGSC_v3.1141,524,963 - 41,632,204 (+)NCBI
Cytogenetic Map1q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
butanal  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chrysene  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (EXP,ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
microcystin-LR  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
N-nitrosodiethylamine  (EXP)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
PCB138  (ISO)
phenylmercury acetate  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
testosterone  (EXP)
tetraphene  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43). Sato M, etal., J Biol Chem. 2009 Nov 6;284(45):31431-40. doi: 10.1074/jbc.M109.014068. Epub 2009 Sep 1.
Additional References at PubMed
PMID:16407149   PMID:27064407  


Genomics

Comparative Map Data
Fndc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,686,856 - 49,769,263 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl149,686,856 - 49,769,263 (+)EnsemblGRCr8
mRatBN7.2147,281,839 - 47,364,247 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,281,844 - 47,364,259 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx147,851,601 - 47,912,467 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,832,549 - 53,893,699 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,927,067 - 47,987,956 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,605,211 - 47,687,499 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,605,262 - 47,687,504 (+)Ensemblrn6Rnor6.0
Rnor_5.0148,905,631 - 48,987,877 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4141,522,019 - 41,583,357 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera142,986,709 - 43,047,709 (+)NCBICelera
RGSC_v3.1141,524,963 - 41,632,204 (+)NCBI
Cytogenetic Map1q11NCBI
FNDC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386159,169,400 - 159,272,108 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6159,169,353 - 159,272,112 (+)Ensemblhg38GRCh38
GRCh376159,590,432 - 159,693,140 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366159,510,417 - 159,613,130 (+)NCBIBuild 36Build 36hg18NCBI36
Celera6160,238,286 - 160,340,329 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6157,060,724 - 157,162,731 (+)NCBIHuRef
CHM1_16159,852,853 - 159,955,448 (+)NCBICHM1_1
T2T-CHM13v2.06160,415,015 - 160,517,654 (+)NCBIT2T-CHM13v2.0
Fndc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39177,957,401 - 8,046,158 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl177,957,401 - 8,046,134 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38177,738,569 - 7,827,340 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl177,738,569 - 7,827,302 (-)Ensemblmm10GRCm38
MGSCv37177,931,433 - 7,997,839 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36177,576,742 - 7,643,148 (-)NCBIMGSCv36mm8
Celera177,616,046 - 7,681,929 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map174.77NCBI
Fndc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554393,252,529 - 3,325,567 (-)Ensembl
ChiLan1.0NW_0049554393,251,851 - 3,356,679 (-)NCBIChiLan1.0ChiLan1.0
FNDC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25179,273,306 - 179,375,519 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16177,178,432 - 177,280,551 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06157,057,862 - 157,160,066 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16162,099,887 - 162,173,981 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,098,598 - 162,173,981 (+)EnsemblpanPan2panpan1.1
FNDC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,501,657 - 48,602,962 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,501,355 - 48,602,336 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha149,344,213 - 49,445,441 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0148,688,184 - 48,789,530 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,687,089 - 48,789,884 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,562,624 - 48,663,825 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,433,345 - 48,534,579 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,993,010 - 49,094,226 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fndc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,483,995 - 143,568,417 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648910,736,182 - 10,819,754 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648910,760,209 - 10,820,377 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FNDC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18,007,321 - 8,106,830 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.118,007,320 - 8,106,875 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,838,883 - 9,939,335 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FNDC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11386,720,558 - 86,868,978 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1386,792,712 - 86,868,321 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604059,109,150 - 59,253,765 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fndc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624929395,705 - 460,563 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624929395,766 - 495,288 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fndc1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12192,027,132 - 192,090,463 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fndc1
416 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:74
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000034842
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat

Markers in Region
RH140011  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2487,524,568 - 87,524,748 (+)MAPPERmRatBN7.2
mRatBN7.2147,310,743 - 47,310,923 (+)MAPPERmRatBN7.2
Rnor_6.0147,634,121 - 47,634,300NCBIRnor6.0
Rnor_6.0488,606,950 - 88,607,129NCBIRnor6.0
Rnor_5.04153,429,639 - 153,429,818UniSTSRnor5.0
Rnor_5.0148,934,508 - 48,934,687UniSTSRnor5.0
RGSC_v3.4487,278,640 - 87,278,819UniSTSRGSC3.4
RGSC_v3.4141,530,041 - 41,530,220UniSTSRGSC3.4
Celera142,994,731 - 42,994,910UniSTS
Celera482,289,643 - 82,289,822UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map1q11UniSTS
AW529829  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2147,302,698 - 47,302,896 (+)MAPPERmRatBN7.2
Rnor_6.0147,626,076 - 47,626,273NCBIRnor6.0
Rnor_5.0148,926,463 - 48,926,660UniSTSRnor5.0
RGSC_v3.4141,521,996 - 41,522,193UniSTSRGSC3.4
Celera142,986,686 - 42,986,883UniSTS
RH 3.4 Map1541.31UniSTS
Cytogenetic Map1q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 151 91 90 59 77 59 6 341 177 11 130 81 92 31 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000034842   ⟹   ENSRNOP00000029878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,686,875 - 49,769,263 (+)Ensembl
mRatBN7.2 Ensembl147,281,853 - 47,364,259 (+)Ensembl
Rnor_6.0 Ensembl147,605,415 - 47,686,843 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089458   ⟹   ENSRNOP00000073034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,686,856 - 49,769,263 (+)Ensembl
mRatBN7.2 Ensembl147,281,853 - 47,364,259 (+)Ensembl
Rnor_6.0 Ensembl147,605,262 - 47,687,504 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094427   ⟹   ENSRNOP00000081553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,707,320 - 49,769,263 (+)Ensembl
mRatBN7.2 Ensembl147,302,307 - 47,364,259 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097447   ⟹   ENSRNOP00000096698
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,686,856 - 49,769,263 (+)Ensembl
mRatBN7.2 Ensembl147,281,844 - 47,364,259 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099286   ⟹   ENSRNOP00000078164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,686,856 - 49,769,263 (+)Ensembl
mRatBN7.2 Ensembl147,281,871 - 47,364,259 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109718   ⟹   ENSRNOP00000095147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,686,856 - 49,769,263 (+)Ensembl
mRatBN7.2 Ensembl147,282,006 - 47,364,259 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155098   ⟹   ENSRNOP00000112578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl149,686,856 - 49,769,263 (+)Ensembl
RefSeq Acc Id: NM_001038615   ⟹   NP_001033704
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,686,875 - 49,769,263 (+)NCBI
mRatBN7.2147,281,858 - 47,364,247 (+)NCBI
Rnor_6.0147,626,099 - 47,686,843 (+)NCBI
Rnor_5.0148,905,631 - 48,987,877 (+)NCBI
RGSC_v3.4141,522,019 - 41,583,357 (+)RGD
Celera142,986,709 - 43,047,709 (+)RGD
Sequence:
RefSeq Acc Id: NM_001412560   ⟹   NP_001399489
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,686,856 - 49,769,263 (+)NCBI
mRatBN7.2147,281,839 - 47,364,247 (+)NCBI
RefSeq Acc Id: XM_063288404   ⟹   XP_063144474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,686,856 - 49,769,232 (+)NCBI
RefSeq Acc Id: XM_063288408   ⟹   XP_063144478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,686,856 - 49,769,232 (+)NCBI
RefSeq Acc Id: XM_063288412   ⟹   XP_063144482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,686,856 - 49,769,232 (+)NCBI
RefSeq Acc Id: XM_063288417   ⟹   XP_063144487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,686,856 - 49,769,232 (+)NCBI
RefSeq Acc Id: NP_001033704   ⟸   NM_001038615
- Peptide Label: isoform 2 precursor
- UniProtKB: Q2Q0I9 (UniProtKB/Swiss-Prot),   A0A128DZ42 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073034   ⟸   ENSRNOT00000089458
Ensembl Acc Id: ENSRNOP00000029878   ⟸   ENSRNOT00000034842
Ensembl Acc Id: ENSRNOP00000096698   ⟸   ENSRNOT00000097447
Ensembl Acc Id: ENSRNOP00000078164   ⟸   ENSRNOT00000099286
Ensembl Acc Id: ENSRNOP00000081553   ⟸   ENSRNOT00000094427
Ensembl Acc Id: ENSRNOP00000095147   ⟸   ENSRNOT00000109718
RefSeq Acc Id: NP_001399489   ⟸   NM_001412560
- Peptide Label: isoform 1 precursor
- UniProtKB: A0A0G2K4G5 (UniProtKB/TrEMBL),   A0A8I5ZT63 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144478   ⟸   XM_063288408
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GLH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144474   ⟸   XM_063288404
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZT63 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144482   ⟸   XM_063288412
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y884 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144487   ⟸   XM_063288417
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AMB4 (UniProtKB/TrEMBL),   A0A8I5Y884 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112578   ⟸   ENSRNOT00000155098
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q2Q0I9-F1-model_v2 AlphaFold Q2Q0I9 1-1779 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689621
Promoter ID:EPDNEW_R134
Type:multiple initiation site
Name:Fndc1_1
Description:fibronectin type III domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0147,605,235 - 47,605,295EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310640 AgrOrtholog
BioCyc Gene G2FUF-61602 BioCyc
Ensembl Genes ENSRNOG00000030210 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000034842 ENTREZGENE
  ENSRNOT00000034842.5 UniProtKB/Swiss-Prot
  ENSRNOT00000089458 ENTREZGENE
  ENSRNOT00000097447 ENTREZGENE
  ENSRNOT00000099286 ENTREZGENE
  ENSRNOT00000109718 ENTREZGENE
  ENSRNOT00000155098 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  TARSH/FNDC1_C UniProtKB/Swiss-Prot
KEGG Report rno:308099 UniProtKB/Swiss-Prot
NCBI Gene 308099 ENTREZGENE
PANTHER FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot
  TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING UniProtKB/Swiss-Prot
Pfam fn3 UniProtKB/Swiss-Prot
  TARSH_C UniProtKB/Swiss-Prot
PhenoGen Fndc1 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000030210 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot
UniProt A0A0G2K4G5 ENTREZGENE, UniProtKB/TrEMBL
  A0A128DZ42 ENTREZGENE, UniProtKB/TrEMBL
  A0A128E118_RAT UniProtKB/TrEMBL
  A0A8I5Y884 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT63 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLH3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LNH6_RAT UniProtKB/TrEMBL
  FNDC1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Fndc1  fibronectin type III domain containing 1      Symbol and Name updated 1299863 APPROVED
2006-03-07 Fndc1  fibronectin type III domain containing 1  Fndc1_predicted  fibronectin type III domain containing 1 (predicted)  Symbol and Name status set to approved 1299863 APPROVED
2005-01-12 Fndc1_predicted  fibronectin type III domain containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED