Snx5 (sorting nexin 5) - Rat Genome Database

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Gene: Snx5 (sorting nexin 5) Rattus norvegicus
Analyze
Symbol: Snx5
Name: sorting nexin 5
RGD ID: 1310190
Description: Enables D1 dopamine receptor binding activity and phosphatidylinositol phosphate binding activity. Involved in epidermal growth factor catabolic process and negative regulation of blood pressure. Located in brush border and endosome. Orthologous to human SNX5 (sorting nexin 5); PARTICIPATES IN retromer-mediated pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC296199; sorting nexin-5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83152,075,258 - 152,094,508 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3152,075,258 - 152,094,877 (-)EnsemblGRCr8
mRatBN7.23131,621,875 - 131,641,127 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3131,621,880 - 131,641,192 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3135,545,743 - 135,564,976 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03144,129,840 - 144,149,072 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03141,833,019 - 141,852,252 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03138,378,032 - 138,397,944 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3138,378,202 - 138,397,870 (-)Ensemblrn6Rnor6.0
Rnor_5.03144,812,043 - 144,831,955 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43132,778,470 - 132,797,964 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3130,517,371 - 130,536,866 (-)NCBICelera
RGSC_v3.13132,684,643 - 132,703,178 (-)NCBI
Cytogenetic Map3q41NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Retromer and sorting nexins in endosomal sorting. Gallon M and Cullen PJ, Biochem Soc Trans. 2015 Feb;43(1):33-47. doi: 10.1042/BST20140290.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The phox domain of sorting nexin 5 lacks phosphatidylinositol 3-phosphate (PtdIns(3)P) specificity and preferentially binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Koharudin LM, etal., J Biol Chem. 2009 Aug 28;284(35):23697-707. doi: 10.1074/jbc.M109.008995. Epub 2009 Jun 24.
4. Inhibitory regulation of EGF receptor degradation by sorting nexin 5. Liu H, etal., Biochem Biophys Res Commun. 2006 Apr 7;342(2):537-46. doi: 10.1016/j.bbrc.2006.01.179. Epub 2006 Feb 9.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Novel role of sorting nexin 5 in renal D(1) dopamine receptor trafficking and function: implications for hypertension. Villar VA, etal., FASEB J. 2013 May;27(5):1808-19. doi: 10.1096/fj.12-208439. Epub 2012 Nov 29.
Additional References at PubMed
PMID:12477932   PMID:15561769   PMID:17148574   PMID:18854019   PMID:19619496   PMID:25468996   PMID:25825816   PMID:34134000  


Genomics

Comparative Map Data
Snx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83152,075,258 - 152,094,508 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3152,075,258 - 152,094,877 (-)EnsemblGRCr8
mRatBN7.23131,621,875 - 131,641,127 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3131,621,880 - 131,641,192 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3135,545,743 - 135,564,976 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03144,129,840 - 144,149,072 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03141,833,019 - 141,852,252 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03138,378,032 - 138,397,944 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3138,378,202 - 138,397,870 (-)Ensemblrn6Rnor6.0
Rnor_5.03144,812,043 - 144,831,955 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43132,778,470 - 132,797,964 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3130,517,371 - 130,536,866 (-)NCBICelera
RGSC_v3.13132,684,643 - 132,703,178 (-)NCBI
Cytogenetic Map3q41NCBI
SNX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382017,941,600 - 17,968,794 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2017,941,597 - 17,969,022 (-)Ensemblhg38GRCh38
GRCh372017,922,244 - 17,949,437 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362017,870,244 - 17,897,490 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342017,870,245 - 17,897,490NCBI
Celera2017,996,791 - 18,024,035 (-)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2017,885,114 - 17,912,355 (-)NCBIHuRef
CHM1_12017,922,265 - 17,949,513 (-)NCBICHM1_1
T2T-CHM13v2.02017,992,739 - 18,019,917 (-)NCBIT2T-CHM13v2.0
Snx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392144,092,043 - 144,112,713 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2144,092,043 - 144,112,826 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382144,250,123 - 144,270,902 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2144,250,123 - 144,270,906 (-)Ensemblmm10GRCm38
MGSCv372144,075,862 - 144,096,267 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362143,941,567 - 143,961,972 (-)NCBIMGSCv36mm8
Celera2145,438,570 - 145,458,831 (-)NCBICelera
Cytogenetic Map2G1NCBI
cM Map270.98NCBI
Snx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541526,785,326 - 26,796,566 (-)Ensembl
ChiLan1.0NW_00495541526,786,836 - 26,805,762 (-)NCBIChiLan1.0ChiLan1.0
SNX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22118,831,386 - 18,858,575 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12018,828,224 - 18,855,413 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02017,901,450 - 17,928,664 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12017,879,605 - 17,907,074 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2017,879,605 - 17,907,074 (-)EnsemblpanPan2panpan1.1
SNX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1245,085,140 - 5,110,942 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl245,084,986 - 5,110,283 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha245,018,013 - 5,043,809 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0245,494,248 - 5,520,060 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl245,494,092 - 5,520,060 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1245,107,154 - 5,133,122 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0245,201,071 - 5,227,082 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0245,477,333 - 5,503,134 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Snx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640153,736,463 - 153,759,793 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364852,168,243 - 2,190,402 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364852,167,987 - 2,191,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1726,352,949 - 26,381,670 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11726,352,945 - 26,381,677 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21729,777,001 - 29,793,996 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SNX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1247,001,684 - 47,028,510 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl247,002,443 - 47,028,293 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660781,669,891 - 1,697,099 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snx5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474118,953,202 - 18,974,545 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474118,954,066 - 18,974,616 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Snx5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15123,896,652 - 123,915,966 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Snx5
106 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:235
Count of miRNA genes:98
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000008934, ENSRNOT00000074606
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
RH134313  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22160,851,088 - 160,851,302 (+)MAPPERmRatBN7.2
mRatBN7.23131,621,937 - 131,622,156 (+)MAPPERmRatBN7.2
Rnor_6.03138,378,261 - 138,378,479NCBIRnor6.0
Rnor_6.02174,535,719 - 174,535,932NCBIRnor6.0
Rnor_5.03144,812,272 - 144,812,490UniSTSRnor5.0
Rnor_5.02193,879,931 - 193,880,144UniSTSRnor5.0
RGSC_v3.42166,980,848 - 166,981,061UniSTSRGSC3.4
RGSC_v3.43132,778,699 - 132,778,917UniSTSRGSC3.4
Celera3130,517,600 - 130,517,818UniSTS
Celera2155,039,521 - 155,039,734UniSTS
RH 3.4 Map31185.1UniSTS
Cytogenetic Map3q41UniSTS
AA851347  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83152,075,936 - 152,076,632 (+)Marker Load Pipeline
mRatBN7.23131,622,553 - 131,623,249 (+)MAPPERmRatBN7.2
Rnor_6.03138,378,877 - 138,379,572NCBIRnor6.0
Rnor_5.03144,812,888 - 144,813,583UniSTSRnor5.0
RGSC_v3.43132,779,315 - 132,780,010UniSTSRGSC3.4
Celera3130,518,216 - 130,518,911UniSTS
RH 3.4 Map31183.1UniSTS
Cytogenetic Map3q41UniSTS
RH140677  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map11519.2UniSTS
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000008934   ⟹   ENSRNOP00000008934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3152,075,258 - 152,086,206 (-)Ensembl
mRatBN7.2 Ensembl3131,621,880 - 131,641,192 (-)Ensembl
Rnor_6.0 Ensembl3138,378,848 - 138,397,508 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000074606   ⟹   ENSRNOP00000066353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3152,075,258 - 152,094,877 (-)Ensembl
mRatBN7.2 Ensembl3131,621,880 - 131,641,192 (-)Ensembl
Rnor_6.0 Ensembl3138,378,202 - 138,397,870 (-)Ensembl
RefSeq Acc Id: NM_001399298   ⟹   NP_001386227
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83152,075,258 - 152,094,508 (-)NCBI
mRatBN7.23131,621,875 - 131,641,127 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001386227 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI60883 (Get FASTA)   NCBI Sequence Viewer  
  B1H267 (Get FASTA)   NCBI Sequence Viewer  
  EDL95174 (Get FASTA)   NCBI Sequence Viewer  
  EDL95175 (Get FASTA)   NCBI Sequence Viewer  
  EDL95176 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066353
  ENSRNOP00000066353.2
Ensembl Acc Id: ENSRNOP00000008934   ⟸   ENSRNOT00000008934
Ensembl Acc Id: ENSRNOP00000066353   ⟸   ENSRNOT00000074606
RefSeq Acc Id: NP_001386227   ⟸   NM_001399298
- UniProtKB: B1H267 (UniProtKB/Swiss-Prot),   A0A8L2Q3Z7 (UniProtKB/TrEMBL)
Protein Domains
BAR   PX

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1H267-F1-model_v2 AlphaFold B1H267 1-404 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692493
Promoter ID:EPDNEW_R3003
Type:multiple initiation site
Name:Snx5_2
Description:sorting nexin 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3004  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03138,397,559 - 138,397,619EPDNEW
RGD ID:13692480
Promoter ID:EPDNEW_R3004
Type:multiple initiation site
Name:Snx5_1
Description:sorting nexin 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3003  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03138,397,866 - 138,397,926EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310190 AgrOrtholog
BioCyc Gene G2FUF-47609 BioCyc
Ensembl Genes ENSRNOG00000006077 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074606 ENTREZGENE
  ENSRNOT00000074606.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot
  3.30.1520.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7382263 IMAGE-MGC_LOAD
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot
  Phox UniProtKB/Swiss-Prot
  PX_dom_sf UniProtKB/Swiss-Prot
  PX_SNX5 UniProtKB/Swiss-Prot
  SNX5 UniProtKB/Swiss-Prot
  SNX5/SNX6/SNX32 UniProtKB/Swiss-Prot
  Vps5_C UniProtKB/Swiss-Prot
MGC_CLONE MGC:188288 IMAGE-MGC_LOAD
NCBI Gene 296199 ENTREZGENE
PANTHER PTHR45850:SF5 UniProtKB/Swiss-Prot
  SORTING NEXIN FAMILY MEMBER UniProtKB/Swiss-Prot
Pfam PF00787 UniProtKB/Swiss-Prot
  Vps5 UniProtKB/Swiss-Prot
PhenoGen Snx5 PhenoGen
PIRSF Snx5_Snx6 UniProtKB/Swiss-Prot
PROSITE PS50195 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000006077 RatGTEx
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot
  SSF64268 UniProtKB/Swiss-Prot
UniProt A0A8L2Q3Z7 ENTREZGENE, UniProtKB/TrEMBL
  B1H267 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Snx5  sorting nexin 5   Snx5_predicted  sorting nexin 5 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Snx5_predicted  sorting nexin 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED