Gbe1 (1,4-alpha-glucan branching enzyme 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Gbe1 (1,4-alpha-glucan branching enzyme 1) Rattus norvegicus
Analyze
Symbol: Gbe1
Name: 1,4-alpha-glucan branching enzyme 1
RGD ID: 1309968
Description: Enables 1,4-alpha-glucan branching enzyme activity and carbohydrate binding activity. Involved in glycogen biosynthetic process and negative regulation of neuron apoptotic process. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in glycogen storage disease IV and pulmonary tuberculosis. Orthologous to human GBE1 (1,4-alpha-glucan branching enzyme 1); PARTICIPATES IN glycogen biosynthetic pathway; congenital sucrase-isomaltase deficiency pathway; glycogen storage disease type III pathway; INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1,4-alpha-glucan-branching enzyme; glucan (1,4-alpha-), branching enzyme 1; LOC288333
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81122,181,194 - 22,446,640 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1122,181,103 - 22,446,638 (+)EnsemblGRCr8
mRatBN7.2118,734,806 - 9,000,226 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl118,734,820 - 9,000,210 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1117,314,505 - 17,568,213 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01110,042,282 - 10,304,941 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0119,221,519 - 9,475,243 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0117,210,169 - 7,485,895 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl117,210,209 - 7,485,890 (+)Ensemblrn6Rnor6.0
Rnor_5.01110,903,698 - 11,174,747 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4118,720,408 - 8,975,471 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera118,665,430 - 8,924,865 (+)NCBICelera
RGSC_v3.1118,720,407 - 8,975,223 (+)NCBI
Cytogenetic Map11p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP)
amitrole  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bucladesine  (ISO)
buspirone  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
carbon nanotube  (ISO)
chloroacetaldehyde  (ISO)
chloroprene  (ISO)
choline  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (EXP,ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
fenofibrate  (EXP,ISO)
flutamide  (EXP)
folic acid  (ISO)
furfural  (ISO)
glafenine  (EXP)
glyphosate  (EXP)
ibuprofen  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
medroxyprogesterone acetate  (ISO)
metformin  (EXP)
methapyrilene  (EXP,ISO)
methidathion  (ISO)
methimazole  (EXP)
monosodium L-glutamate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nickel dichloride  (EXP,ISO)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenformin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
T-2 toxin  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triadimefon  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
Tungsten carbide  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
cytosol  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Hepatic and neuromuscular forms of glycogen storage disease type IV caused by mutations in the same glycogen-branching enzyme gene. Bao Y, etal., J Clin Invest. 1996 Feb 15;97(4):941-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Risk prediction of pulmonary tuberculosis using genetic and conventional risk factors in adult Korean population. Hong EP, etal., PLoS One. 2017 Mar 29;12(3):e0174642. doi: 10.1371/journal.pone.0174642. eCollection 2017.
5. Polyglucosan neurotoxicity caused by glycogen branching enzyme deficiency can be reversed by inhibition of glycogen synthase. Kakhlon O, etal., J Neurochem. 2013 Oct;127(1):101-13. doi: 10.1111/jnc.12277. Epub 2013 May 9.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Single fiber analyses of glycogen-related proteins reveal their differential association with glycogen in rat skeletal muscle. Murphy RM, etal., Am J Physiol Cell Physiol. 2012 Dec 1;303(11):C1146-55. doi: 10.1152/ajpcell.00252.2012. Epub 2012 Sep 26.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. Novel pathogenic variants in GBE1 causing fetal akinesia deformation sequence and severe neuromuscular form of glycogen storage disease type IV. Radhakrishnan P, etal., Clin Dysmorphol. 2019 Jan;28(1):17-21. doi: 10.1097/MCD.0000000000000248.
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Glycogen-binding protein components of rat tissues. Satoh K and Sato K, Biochem Biophys Res Commun. 1980 Sep 16;96(1):28-33.
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:14766980   PMID:19056867   PMID:23533145   PMID:26199317  


Genomics

Comparative Map Data
Gbe1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81122,181,194 - 22,446,640 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1122,181,103 - 22,446,638 (+)EnsemblGRCr8
mRatBN7.2118,734,806 - 9,000,226 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl118,734,820 - 9,000,210 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1117,314,505 - 17,568,213 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01110,042,282 - 10,304,941 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0119,221,519 - 9,475,243 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0117,210,169 - 7,485,895 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl117,210,209 - 7,485,890 (+)Ensemblrn6Rnor6.0
Rnor_5.01110,903,698 - 11,174,747 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4118,720,408 - 8,975,471 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera118,665,430 - 8,924,865 (+)NCBICelera
RGSC_v3.1118,720,407 - 8,975,223 (+)NCBI
Cytogenetic Map11p11NCBI
GBE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38381,489,703 - 81,761,645 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl381,489,699 - 81,761,781 (-)Ensemblhg38GRCh38
GRCh37381,538,854 - 81,810,796 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36381,621,541 - 81,893,640 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34381,621,547 - 81,893,435NCBI
Celera382,281,720 - 82,553,857 (-)NCBICelera
Cytogenetic Map3p12.2NCBI
HuRef381,557,582 - 81,828,544 (-)NCBIHuRef
CHM1_1381,490,987 - 81,762,964 (-)NCBICHM1_1
T2T-CHM13v2.0381,543,135 - 81,815,065 (-)NCBIT2T-CHM13v2.0
Gbe1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391670,110,837 - 70,366,608 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1670,110,837 - 70,366,604 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381670,313,949 - 70,569,720 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1670,313,949 - 70,569,716 (+)Ensemblmm10GRCm38
MGSCv371670,314,332 - 70,569,961 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361670,196,767 - 70,452,396 (+)NCBIMGSCv36mm8
Celera1670,562,114 - 70,812,345 (+)NCBICelera
Cytogenetic Map16C2NCBI
cM Map1640.19NCBI
Gbe1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540710,692,303 - 10,963,489 (+)Ensembl
ChiLan1.0NW_00495540710,692,082 - 10,959,236 (+)NCBIChiLan1.0ChiLan1.0
GBE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2281,606,232 - 81,883,060 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1381,611,018 - 81,887,850 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0381,587,604 - 81,861,214 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1383,632,214 - 83,904,546 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl383,632,215 - 83,904,546 (-)EnsemblpanPan2panpan1.1
GBE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1315,742,744 - 6,010,881 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl315,742,744 - 6,093,612 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha315,809,115 - 6,081,275 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0315,750,707 - 6,019,215 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl315,750,707 - 6,055,820 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1315,717,055 - 5,986,758 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0315,767,815 - 6,037,553 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0316,156,072 - 6,424,439 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101958945
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049717,182,545 - 7,322,307 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365051,974,264 - 2,241,427 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365052,077,206 - 2,242,079 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GBE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13173,634,454 - 173,914,756 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113173,634,401 - 173,909,646 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213184,012,385 - 184,127,125 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GBE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12295,228,926 - 95,503,798 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2295,229,133 - 95,504,840 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604171,375,169 - 71,641,554 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gbe1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248742,157,524 - 2,444,111 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248742,157,291 - 2,444,786 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Gbe1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1471,470,420 - 71,714,918 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gbe1
1394 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000075964   ⟹   ENSRNOP00000067909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl117,422,272 - 7,485,890 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076695   ⟹   ENSRNOP00000068309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1122,181,103 - 22,420,168 (+)Ensembl
mRatBN7.2 Ensembl118,734,918 - 8,974,767 (+)Ensembl
Rnor_6.0 Ensembl117,210,209 - 7,413,999 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084765   ⟹   ENSRNOP00000068640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1122,181,253 - 22,446,638 (+)Ensembl
mRatBN7.2 Ensembl118,734,820 - 9,000,210 (+)Ensembl
Rnor_6.0 Ensembl117,265,828 - 7,485,211 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000122871   ⟹   ENSRNOP00000101204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1122,181,103 - 22,446,637 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000129667   ⟹   ENSRNOP00000102922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1122,181,103 - 22,446,637 (+)Ensembl
RefSeq Acc Id: NM_001100502   ⟹   NP_001093972
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81122,181,276 - 22,446,640 (+)NCBI
mRatBN7.2118,734,862 - 9,000,226 (+)NCBI
Rnor_6.0117,210,169 - 7,485,895 (+)NCBI
Rnor_5.01110,903,698 - 11,174,747 (+)NCBI
RGSC_v3.4118,720,408 - 8,975,471 (+)RGD
Celera118,665,430 - 8,924,865 (+)RGD
Sequence:
RefSeq Acc Id: XM_039088228   ⟹   XP_038944156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81122,240,702 - 22,446,640 (+)NCBI
mRatBN7.2118,795,451 - 9,000,221 (+)NCBI
RefSeq Acc Id: XM_039088229   ⟹   XP_038944157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81122,181,194 - 22,394,649 (+)NCBI
mRatBN7.2118,734,806 - 8,948,238 (+)NCBI
RefSeq Acc Id: XM_063270436   ⟹   XP_063126506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81122,240,702 - 22,394,649 (+)NCBI
RefSeq Acc Id: NP_001093972   ⟸   NM_001100502
- UniProtKB: A6K4X8 (UniProtKB/TrEMBL),   A6K4X9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068640   ⟸   ENSRNOT00000084765
Ensembl Acc Id: ENSRNOP00000067909   ⟸   ENSRNOT00000075964
Ensembl Acc Id: ENSRNOP00000068309   ⟸   ENSRNOT00000076695
RefSeq Acc Id: XP_038944157   ⟸   XM_039088229
- Peptide Label: isoform X2
- UniProtKB: A6K4X9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944156   ⟸   XM_039088228
- Peptide Label: isoform X1
- UniProtKB: Q5EB55 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126506   ⟸   XM_063270436
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000101204   ⟸   ENSRNOT00000122871
Ensembl Acc Id: ENSRNOP00000102922   ⟸   ENSRNOT00000129667
Protein Domains
Glycoside hydrolase family 13 N-terminal   Glycosyl hydrolase family 13 catalytic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTB2-F1-model_v2 AlphaFold A0A0G2JTB2 1-655 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698003
Promoter ID:EPDNEW_R8526
Type:multiple initiation site
Name:Gbe1_1
Description:1,4-alpha-glucan-branching enzyme
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0117,210,210 - 7,210,270EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309968 AgrOrtholog
BioCyc Gene G2FUF-22274 BioCyc
BioCyc Pathway PWY-5067 [glycogen biosynthesis II (from UDP-D-Glucose)] BioCyc
BioCyc Pathway Image PWY-5067 BioCyc
Ensembl Genes ENSRNOG00000051232 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000076695.4 UniProtKB/TrEMBL
  ENSRNOT00000084765.3 UniProtKB/TrEMBL
  ENSRNOT00000122871.1 UniProtKB/TrEMBL
  ENSRNOT00000129667 ENTREZGENE
  ENSRNOT00000129667.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  2.60.40.1180 UniProtKB/TrEMBL
  Glycosidases UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7368249 IMAGE-MGC_LOAD
InterPro A-amylase_b_C UniProtKB/TrEMBL
  Branching_enzy UniProtKB/TrEMBL
  Glyco_hydro_13_cat_dom UniProtKB/TrEMBL
  Glyco_hydro_13_N UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/TrEMBL
  Glyco_hydro_catalytic_core UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
KEGG Report rno:288333 UniProtKB/TrEMBL
MGC_CLONE MGC:109648 IMAGE-MGC_LOAD
NCBI Gene 288333 ENTREZGENE
PANTHER 1,4-ALPHA-GLUCAN-BRANCHING ENZYME UniProtKB/TrEMBL
  PTHR43651 UniProtKB/TrEMBL
Pfam Alpha-amylase UniProtKB/TrEMBL
  Alpha-amylase_C UniProtKB/TrEMBL
  CBM_48 UniProtKB/TrEMBL
PharmGKB GBE1 RGD
PhenoGen Gbe1 PhenoGen
PIRSF GlgB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051232 RatGTEx
SMART Aamy UniProtKB/TrEMBL
Superfamily-SCOP Glyco_hydro_cat UniProtKB/TrEMBL
  Glycosyl hydrolase domain UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A096MJY6_RAT UniProtKB/TrEMBL
  A0A0G2JTB2_RAT UniProtKB/TrEMBL
  A0ABK0LA09_RAT UniProtKB/TrEMBL
  A0ABK0LHH2_RAT UniProtKB/TrEMBL
  A6K4X8 ENTREZGENE, UniProtKB/TrEMBL
  A6K4X9 ENTREZGENE, UniProtKB/TrEMBL
  A6K4Y0_RAT UniProtKB/TrEMBL
  Q5EB55 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-18 Gbe1  1,4-alpha-glucan branching enzyme 1  Gbe1  glucan (1,4-alpha-), branching enzyme 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Gbe1  glucan (1,4-alpha-), branching enzyme 1  Gbe1_predicted  glucan (1,4-alpha-), branching enzyme 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Gbe1_predicted  glucan (1,4-alpha-), branching enzyme 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED