Kif5c (kinesin family member 5C) - Rat Genome Database

Name: Kif5c
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Kif5c (kinesin family member 5C) Rattus norvegicus

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Symbol:

Kif5c

Name:

kinesin family member 5C

RGD ID:

1308539

Description:

Enables ATP hydrolysis activity; apolipoprotein receptor binding activity; and microtubule binding activity. Involved in anterograde axonal protein transport and intracellular mRNA localization. Located in dendrite. Is active in GABA-ergic synapse and postsynaptic cytosol. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 2 and schizophrenia. Orthologous to human KIF5C (kinesin family member 5C); PARTICIPATES IN mitochondria transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bis(2-ethylhexyl) phthalate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

kinesin heavy chain; kinesin heavy chain isoform 5C; kinesin heavy chain neuron-specific 2; kinesin-1; LOC311024

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	54,441,266 - 54,591,630 (+)	NCBI		GRCr8
mRatBN7.2	3	34,032,082 - 34,185,597 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	34,032,105 - 34,182,413 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	37,402,568 - 37,553,043 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	45,987,291 - 46,137,761 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	43,799,352 - 43,950,019 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	35,014,157 - 35,257,417 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	35,014,538 - 35,257,407 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	40,150,177 - 40,380,889 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	30,602,210 - 30,755,482 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	30,498,932 - 30,637,511 (+)	NCBI
Celera	3	32,217,717 - 32,366,850 (+)	NCBI		Celera
Cytogenetic Map	3	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease 3 (ISO)

amyotrophic lateral sclerosis type 1 (ISO)

autosomal dominant intellectual developmental disorder 1 (ISO)

complex cortical dysplasia with other brain malformations (ISO)

complex cortical dysplasia with other brain malformations 2 (ISO)

Developmental Disease (ISO)

Duane retraction syndrome (ISO)

genetic disease (ISO)

jaw-winking syndrome (ISO)

leiomyoma (ISO)

microcephaly (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

8-Br-cAMP (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

antimycin A (ISO)

aristolochic acid A (ISO)

azoxystrobin (ISO)

benzatropine (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

butanal (ISO)

Butylbenzyl phthalate (EXP)

calcitriol (ISO)

cannabidiol (ISO)

chlordecone (ISO)

choline (ISO)

cisplatin (ISO)

clozapine (ISO)

copper atom (ISO)

copper(0) (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

deguelin (ISO)

dibutyl phthalate (EXP)

diclofenac (EXP)

diethyl phthalate (EXP)

diisobutyl phthalate (EXP)

diisononyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

endosulfan (EXP)

Enterolactone (ISO)

enzalutamide (ISO)

ethanol (ISO)

fenpyroximate (ISO)

folic acid (ISO)

haloperidol (ISO)

L-methionine (ISO)

lead(0) (ISO)

manganese(II) chloride (EXP)

methoxychlor (EXP)

methylmercury chloride (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-methyl-4-phenylpyridinium (EXP,ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

p-chloromercuribenzoic acid (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

pentanal (ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP)

picoxystrobin (ISO)

pirinixic acid (ISO)

poly(I:C) (EXP)

potassium chromate (ISO)

propanal (ISO)

pyrimidifen (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tebufenpyrad (ISO)

tert-butyl hydroperoxide (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triticonazole (EXP)

valproic acid (EXP,ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterograde axonal protein transport (IMP)

anterograde dendritic transport of messenger ribonucleoprotein complex (ISO)

intracellular mRNA localization (IMP)

microtubule-based movement (IEA)

motor neuron axon guidance (ISO)

mRNA transport (ISO,ISS)

Cellular Component

axon cytoplasm (IEA)

axonal growth cone (ISO)

ciliary rootlet (ISO)

cytoplasm (IEA,ISO)

dendrite (IDA)

dendrite cytoplasm (IEA)

distal axon (ISO)

GABA-ergic synapse (IDA)

microtubule (IEA)

neuron projection (ISO)

neuronal cell body (ISO)

postsynaptic cytosol (IDA)

Molecular Function

apolipoprotein receptor binding (IPI)

ATP binding (IEA)

ATP hydrolysis activity (IDA)

microtubule binding (IDA,IEA)

microtubule motor activity (IEA)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mitochondria transport pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Expression profiling of the cellular processes in uterine leiomyomas: omic approaches and IGF-2 association with leiomyosarcomas.	Bae SM, etal., Cancer Res Treat. 2004 Feb;36(1):31-42. doi: 10.4143/crt.2004.36.1.31. Epub 2004 Feb 29.
2.	Genetic modifiers and subtypes in schizophrenia: investigations of age at onset, severity, sex and family history.	Bergen SE, etal., Schizophr Res. 2014 Apr;154(1-3):48-53. doi: 10.1016/j.schres.2014.01.030. Epub 2014 Feb 26.
3.	Shank1 mRNA: dendritic transport by kinesin and translational control by the 5'untranslated region.	Falley K, etal., Traffic. 2009 Jul;10(7):844-57. doi: 10.1111/j.1600-0854.2009.00912.x. Epub 2009 Apr 11.
4.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
6.	Kinesin expression in the central nervous system of humans and transgenic hSOD1G93A mice with amyotrophic lateral sclerosis.	Kuzma-Kozakiewicz M, etal., Neurodegener Dis. 2013;12(2):71-80. doi: 10.1159/000339529. Epub 2012 Sep 21.
7.	Regulation of mitochondrial transport in neurons.	Lin MY and Sheng ZH, Exp Cell Res. 2015 May 15;334(1):35-44. doi: 10.1016/j.yexcr.2015.01.004. Epub 2015 Jan 19.
8.	Kinesin and ncd bind through a single head to microtubules and compete for a shared MT binding site.	Lockhart A, etal., J Mol Biol. 1995 Jun 16;249(4):763-71.
9.	Huntingtin mediates dendritic transport of beta-actin mRNA in rat neurons.	Ma B, etal., Sci Rep. 2011;1:140. Epub 2011 Nov 3.
10.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
11.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
12.	GOA pipeline	RGD automated data pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.	Sepulveda-Falla D, etal., J Clin Invest. 2014 Apr;124(4):1552-67. doi: 10.1172/JCI66407. Epub 2014 Feb 24.
16.	c-Jun NH2-terminal kinase (JNK)-interacting protein-3 (JIP3) regulates neuronal axon elongation in a kinesin- and JNK-dependent manner.	Sun T, etal., J Biol Chem. 2013 May 17;288(20):14531-43. doi: 10.1074/jbc.M113.464453. Epub 2013 Apr 10.
17.	Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin.	Twelvetrees AE, etal., Neuron. 2010 Jan 14;65(1):53-65. doi: 10.1016/j.neuron.2009.12.007.
18.	Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules.	Verhey KJ, etal., J Cell Biol. 2001 Mar 5;152(5):959-70.
19.	The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility.	Wang X and Schwarz TL, Cell. 2009 Jan 9;136(1):163-74. doi: 10.1016/j.cell.2008.11.046.
20.	The RNA-binding protein MARTA2 regulates dendritic targeting of MAP2 mRNAs in rat neurons.	Zivraj KH, etal., J Neurochem. 2013 Mar;124(5):670-84. doi: 10.1111/jnc.12079. Epub 2013 Jan 20.

Additional References at PubMed

PMID:9405049	PMID:9428521	PMID:10964943	PMID:11319135	PMID:15644324	PMID:16018997	PMID:16301330	PMID:17887960	PMID:19608740	PMID:20032309	PMID:21700703	PMID:22871113
PMID:24286867	PMID:24940781	PMID:26767417	PMID:27699600	PMID:28302907	PMID:29476059	PMID:31084716	PMID:34348158	PMID:36675068

Genomics

Comparative Map Data

Kif5c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	54,441,266 - 54,591,630 (+)	NCBI		GRCr8
mRatBN7.2	3	34,032,082 - 34,185,597 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	34,032,105 - 34,182,413 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	37,402,568 - 37,553,043 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	45,987,291 - 46,137,761 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	43,799,352 - 43,950,019 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	35,014,157 - 35,257,417 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	35,014,538 - 35,257,407 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	40,150,177 - 40,380,889 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	30,602,210 - 30,755,482 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	30,498,932 - 30,637,511 (+)	NCBI
Celera	3	32,217,717 - 32,366,850 (+)	NCBI		Celera
Cytogenetic Map	3	q12	NCBI

KIF5C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	148,875,227 - 149,026,759 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	148,875,227 - 149,026,759 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	149,632,796 - 149,883,273 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	149,349,289 - 149,396,266 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 36	2	149,502,042 - 149,591,519 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	143,347,002 - 143,497,189 (+)	NCBI		Celera
Cytogenetic Map	2	q23.1-q23.2	NCBI
HuRef	2	141,692,099 - 141,781,519 (+)	NCBI		HuRef
HuRef	2	141,630,811 - 141,685,094 (+)	NCBI		HuRef
CHM1_1	2	149,799,659 - 149,889,137 (+)	NCBI		CHM1_1
CHM1_1	2	149,638,662 - 149,692,791 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	149,325,585 - 149,477,131 (+)	NCBI		T2T-CHM13v2.0

Kif5c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	49,509,298 - 49,664,790 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	49,509,310 - 49,664,790 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	49,619,286 - 49,774,778 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	49,619,298 - 49,774,778 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	49,474,834 - 49,630,298 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	49,441,323 - 49,596,787 (+)	NCBI		MGSCv36	mm8
Celera	2	51,292,276 - 51,447,919 (+)	NCBI		Celera
Cytogenetic Map	2	C1.1	NCBI
cM Map	2	28.68	NCBI

Kif5c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955440	14,754,639 - 14,854,406 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955440	14,754,931 - 14,854,090 (+)	NCBI	ChiLan1.0	ChiLan1.0

KIF5C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	25,901,834 - 26,053,898 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	25,916,801 - 26,068,844 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	10,836,356 - 10,987,683 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	153,235,329 - 153,387,221 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	153,235,329 - 153,387,221 (+)	Ensembl	panpan1.1		panPan2

KIF5C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	19	50,535,622 - 50,684,485 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	19	50,535,456 - 50,668,738 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	19	50,659,035 - 50,807,788 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	19	52,008,886 - 52,158,206 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	19	52,008,672 - 52,154,871 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	19	50,652,619 - 50,801,801 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	19	50,787,472 - 50,935,851 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	19	52,186,427 - 52,334,911 (+)	NCBI		UU_Cfam_GSD_1.0

Kif5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	113,186,109 - 113,337,599 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	28,280,095 - 28,431,695 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	28,282,921 - 28,431,638 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KIF5C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	3,190,343 - 3,361,410 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	3,190,341 - 3,361,470 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	2,730,440 - 2,901,563 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KIF5C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	34,285,048 - 34,441,918 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	34,285,037 - 34,444,863 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	165,078,867 - 165,231,441 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kif5c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624866	1,526,638 - 1,698,301 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624866	1,526,647 - 1,698,113 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Kif5c
1227 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	53
Count of miRNA genes:	49
Interacting mature miRNAs:	51
Transcripts:	ENSRNOT00000006341
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298073	Cm13	Cardiac mass QTL 13	2.5		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	25013911	38192233	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	15005422	76927699	Rat
631832	Sach1	Saccharin preference QTL 1	2.7	0.02	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	3	27494621	44188411	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	28249687	73249687	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
2313093	Bmd77	Bone mineral density QTL 77	2.2	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	3	27494621	50302886	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	18311454	47233430	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	18311454	47233430	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	18311454	47233430	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	30684642	75684642	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	18311454	47233430	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	10778704	50302886	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	18311454	47233430	Rat
2313101	Bmd76	Bone mineral density QTL 76	3.6	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	3	27494621	50302886	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	18311454	47233430	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	18311454	47233430	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	28249687	73249687	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
12879868	Am6	Aortic mass QTL 6		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	31426403	70668733	Rat
11565451	Bw177	Body weight QTL 177		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	3	31426403	70668733	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
11565452	Kidm57	Kidney mass QTL 57		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	31426403	70668733	Rat
12879866	Cm94	Cardiac mass QTL 94		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	31426403	70668733	Rat
12879867	Cm95	Cardiac mass QTL 95		0.047	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	31426403	70668733	Rat
2302055	Pia30	Pristane induced arthritis QTL 30	3.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	3	27936919	72936919	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	78196190	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	28468571	73468571	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	28468571	73468571	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	17374703	35528639	Rat
2313079	Bss73	Bone structure and strength QTL 73	1.5		tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	3	27494621	50302886	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	30684642	75684642	Rat
2313076	Bss74	Bone structure and strength QTL 74	2	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	3	27494621	50302886	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	33703347	61017857	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	28249687	73249687	Rat
10450804	Scl70	Serum cholesterol level QTL 70	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	20714090	65714090	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	30356773	98535386	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	28249687	73249687	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	16954708	61954708	Rat
10450794	Scl69	Serum cholesterol level QTL 69	6.3	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	20714090	65714090	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	28249687	73249687	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	104104347	Rat
2313049	Bss72	Bone structure and strength QTL 72	2.6	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	3	27494621	50302886	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
2301400	Cm68	Cardiac mass QTL 68		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	31426403	70668733	Rat

Markers in Region

D3Got22

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	34,105,497 - 34,105,633 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	35,176,560 - 35,176,695	NCBI	Rnor6.0
Rnor_5.0	3	40,303,203 - 40,303,338	UniSTS	Rnor5.0
RGSC_v3.4	3	30,678,696 - 30,678,832	RGD	RGSC3.4
RGSC_v3.4	3	30,678,697 - 30,678,832	UniSTS	RGSC3.4
RGSC_v3.1	3	30,575,068 - 30,575,204	RGD
Celera	3	32,289,943 - 32,290,078	UniSTS
Cytogenetic Map	3	q12	UniSTS

RH142774

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	34,182,586 - 34,182,774 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	35,254,407 - 35,254,594	NCBI	Rnor6.0
Rnor_5.0	3	40,381,063 - 40,381,250	UniSTS	Rnor5.0
RGSC_v3.4	3	30,755,656 - 30,755,844	UniSTS	RGSC3.4
Celera	3	32,367,024 - 32,367,211	UniSTS
RH 3.4 Map	3	411.51	UniSTS
Cytogenetic Map	3	q12	UniSTS

BE096005

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	34,168,985 - 34,169,159 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	35,240,806 - 35,240,979	NCBI	Rnor6.0
Rnor_5.0	3	40,367,462 - 40,367,635	UniSTS	Rnor5.0
RGSC_v3.4	3	30,742,055 - 30,742,228	UniSTS	RGSC3.4
Celera	3	32,353,423 - 32,353,596	UniSTS
RH 3.4 Map	3	413.71	UniSTS
Cytogenetic Map	3	q12	UniSTS

PMC133732P1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	34,106,821 - 34,107,282 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	35,177,884 - 35,178,344	NCBI	Rnor6.0
Rnor_5.0	3	40,304,527 - 40,304,987	UniSTS	Rnor5.0
RGSC_v3.4	3	30,680,021 - 30,680,481	UniSTS	RGSC3.4
Celera	3	32,291,267 - 32,291,727	UniSTS
Cytogenetic Map	3	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	10	49	113	88	87	56	25	56	6	213	95	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006341 ⟹ ENSRNOP00000006341

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	34,032,105 - 34,182,413 (+)	Ensembl
Rnor_6.0 Ensembl	3	35,014,538 - 35,239,888 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081744 ⟹ ENSRNOP00000071329

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	34,032,105 - 34,182,413 (+)	Ensembl
Rnor_6.0 Ensembl	3	35,175,313 - 35,257,407 (+)	Ensembl

RefSeq Acc Id:

NM_001107730 ⟹ NP_001101200

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	54,441,307 - 54,591,630 (+)	NCBI
mRatBN7.2	3	34,032,105 - 34,182,413 (+)	NCBI
Rnor_6.0	3	35,014,187 - 35,254,233 (+)	NCBI
Rnor_5.0	3	40,150,177 - 40,380,889 (+)	NCBI
RGSC_v3.4	3	30,602,210 - 30,755,482 (+)	RGD
Celera	3	32,217,717 - 32,366,850 (+)	RGD

Sequence:

show sequence

GGTGCCGGAGCGAGGTGGTGCTGATGCAGGATGGCTGAGCGCGCCGGAGCCCGGGAGGTCTGAG
CCGGGCTGGGATTGCTCCCTAAGCATCGCCTAGTCCGCCCGCCGCTTGGTCGCGGGCAGGTGGA
CCAGGGCGCAGGACCGGGCTGGAGGTCAGCAGCAGGGCGGCCCAGCTGCTCTCCTTCCCGGCGG
CAGAGCTGCTGGGCGTCCGGCGCAGGCTTGCGATGACCTGCTGAGAAGCTGCGGGAGGCGGCCT
AGCAGCCGGCAGCGGTTGGCTCGCGGCCTCTTTGGTGGAGCTGCCCAGCCGGACCCCCTATCCC
ATCCCTGTGTCCCCTCCTGCCGCGGCCCGAGATGGCGGATCCAGCCGAATGCAGCATCAAAGTG
ATGTGCCGGTTCCGGCCCCTCAACGAAGCTGAGATCCTCCGCGGGGACAAATTCATCCCCAAAT
TCAAAGGCGAGGAGACGGTGGTGATCGGGCAAGGGAAGCCGTATGTCTTTGACCGAGTTCTGCC
GCCCAACACAACCCAGGAGCAGGTCTACAATGCCTGTGCGAAGCAGATTGTCAAAGATGTCCTC
GAGGGTTACAATGGGACAATTTTTGCATACGGGCAGACTTCATCAGGAAAAACTCATACCATGG
AGGGGAAGCTGCACGATCCTCAGCTTATGGGTATCATACCCAGGATCGCACACGATATTTTCGA
TCACATCTATTCCATGGATGAGAACTTGGAGTTTCATATCAAGGTTTCCTATTTTGAGATCTAC
TTGGACAAAATAAGGGACTTGCTTGACGTGTCCAAGACCAACTTGGCTGTTCATGAAGACAAAA
ACAGAGTCCCCTATGTAAAGGGGTGCACCGAGAGGTTTGTGTCAAGCCCGGAGGAGGTCATGGA
TGTGATCGATGAGGGCAAAGCAAACCGACATGTGGCTGTGACAAACATGAACGAACACAGCTCC
AGGAGTCACAGTATCTTCCTGATTAACATTAAACAAGAGAATGTGGAGACTGAAAAAAAACTCA
GCGGGAAGCTGTATTTGGTTGATTTGGCTGGGAGTGAAAAGGTCAGCAAAACTGGTGCCGAGGG
AGCTGTTCTTGATGAAGCTAAAAATATCAACAAGTCTTTGTCTGCTCTTGGAAATGTGATCTCT
GCCTTGGCAGAAGGGACAAAAACACATGTGCCATACCGGGACAGCAAGATGACTCGGATTCTCC
AGGACTCTCTGGGTGGGAACTGCAGGACCACCATTGTCATTTGCTGTTCTCCTTCAGTCTTCAA
TGAGGCTGAGACCAAGTCCACGCTGATGTTTGGACAGAGAGCAAAGACCATCAAGAATACAGTC
TCTGTGAACTTGGAACTAACAGCAGAAGAATGGAAGAAGAAATATGAAAAAGAGAAAGAGAAGA
ATAAGGCCCTGAAGAGTGTCATCCAGCATCTGGAGGTGGAGCTGAACAGGTGGAGGAACGGGGA
AGCTGTGCCTGAGGATGAACAGATCAGTGCCAAGGACCAGAAGAACCTGGAGCCCTGCGACAAC
ACACCCATCATAGACAACATCACACCTGTGGTTGACGGCATCTCTGCTGAGAAAGAGAAGTATG
ACGAGGAAATCACCAGTCTGTACCGACAGCTGGATGACAAGGACGATGAAATTAACCAGCAGAG
CCAGCTGGCTGAAAAGCTGAAGCAACAGATGTTGGATCAGGACGAGCTTCTAGCTTCCACCAGA
AGGGACTACGAGAAAATCCAGGAGGAGCTGACCCGCCTCCAGATTGAAAACGAGGCGGCTAAAG
ACGAGGTGAAGGAGGTCCTCCAGGCCCTGGAGGAGCTGGCTGTCAATTACGACCAGAAGTCACA
GGAAGTGGAGGACAAGACCCGGGCCAACGAGCAACTGACCGATGAGCTGGCCCAGAAAACGACG
ACACTGACAACCACCCAGCGGGAGCTGAGTCAGCTACAGGAGCTTAGCAACCACCAGAAGAAGA
GGGCCACGGAGATCCTGAACCTGCTTCTCAAGGATCTGGGCGAGATAGGTGGAATTATCGGCAC
CAACGATGTGAAGACCCTGGCAGATGTGAATGGAGTCATCGAAGAGGAGTTCACCATGGCCCGC
CTGTACATTAGCAAGATGAAGTCGGAGGTCAAGTCTCTCGTGAACCGCAGCAAGCAGCTGGAGA
GCGCCCAGACGGACTCCAACAGGAAGATGAATGCCAGCGAGCGGGAGCTGGCAGCTTGCCAGTT
GCTTATCTCGCAGCATGAAGCCAAGATCAAGTCTCTGACAGACTACATGCAGAACATGGAACAG
AAGAGGCGGCAGCTGGAAGAGTCGCAGGACTCCCTCAGCGAGGAGCTGGCCAAGCTCCGGGCCC
AAGAAAAAATGCACGAAGTCAGTTTCCAAGATAAGGAAAAGGAGCACCTGACGAGGCTGCAGGA
TGCTGAGGAAGTGAAGAAGGCTCTGGAGCAGCAGATGGAGAGTCACCGGGAAGCGCACCAAAAG
CAGCTGTCCAGACTTCGTGATGAGATTGAGGAGAAGCAGAGAATCATTGATGAGATTCGGGATT
TGAATCAGAAGCTGCAACTGGAACAGGAGAGGCTCAGCTCTGATTATAACAAGCTGAAAATAGA
GGACCAGGAGAGAGAAGTGAAGCTGGAGAAGCTCCTATTGCTCAATGACAAAAGAGAGCAAGCC
AGGGAGGACCTCAAGGGACTGGAAGAGACTGTGTCCAGAGAACTCCAGACTCTTCACAACCTGC
GCAAACTCTTCGTCCAGGACTTGACCACCCGGGTGAAAAAGAGTGTGGAGCTGGACAGCGACGA
TGGAGGGGGTAGTGCCGCCCAGAAGCAGAAGATCTCCTTCCTGGAGAACAACCTGGAGCAGCTT
ACCAAGGTGCACAAGCAGCTGGTCCGGGACAATGCGGATTTGCGCTGTGAACTCCCCAAGCTGG
AGAAGAGGCTCCGTGCTACTGCAGAGCGTGTCAAGGCCTTGGAGAGTGCGCTCAAAGAGGCCAA
GGAGAATGCCATGAGGGACCGAAAGCGCTACCAGCAGGAAGTGGATCGCATCAAGGAGGCTGTG
CGGGCCAAGAACATGGCCAGGAGGGCACATTCGGCTCAGATCGCCAAGCCCATCCGCCCAGGAC
ACTATCCTGCATCATCTCCAACAGCCGTCCATGCCGTCCGGGGAGGAGGTGGATCTTCAAACTC
CACTCACTACCAGAAGTAAATGCAGAATATGACCCCACGTAGCATGAAAAGGACTATATTAGTC
ATCAGTTCCTTTATTTCCCTCCTATACAGTTTCCGTTTCTTTTTACACTTGCTTGCCCAGCCGT
CTGTAGTACACCAGATTCAGGTGTTTGCGCTGTGTAGAATTTGTGTGCACAGATACGTGCTTGG
ATCCTTCTCCTAAGAAGTTGGAAGGAGGTGGTTACGCAATACCCACTTCCTGCTCAGACGTTGC
CACTTCTCAGCCTCCGGGGTTGCGTGGTCTCTGGAGGCCCCTGCAGTGCACTGGCCCATTGGAA
TGGAATGCCCTACTGTGCTATCCCAGAGGGACAACCAAGTGCTGTGGAACCAGTGACCATGCTC
TGCCTCGACTGTCCGGTTTCCTGTAAAATAAACACATCACTTTATATTTTTAGGGAACAAAAAA
AAGTGCTGCTATAGGGTTCAAAATTTTCATTCTGAACACTTTTCCAAAACCAAC

hide sequence

RefSeq Acc Id:

XM_063283548 ⟹ XP_063139618

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	54,441,266 - 54,582,391 (+)	NCBI

RefSeq Acc Id:

XM_063283549 ⟹ XP_063139619

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	54,441,266 - 54,591,138 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101200	(Get FASTA)	NCBI Sequence Viewer
	XP_063139618	(Get FASTA)	NCBI Sequence Viewer
	XP_063139619	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM00464	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006341.8
	ENSRNOP00000071329.2
	ENSRNOP00055001902
	ENSRNOP00060045882
	ENSRNOP00065009763
GenBank Protein	P56536	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001101200 ⟸ NM_001107730

- UniProtKB:

P56536 (UniProtKB/Swiss-Prot), G3V6L4 (UniProtKB/Swiss-Prot), A0A0G2K070 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYN
ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLE
FHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRH
VAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNIN
KSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMF
GQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVIQHLEVELNRWRNGEAVPEDEQISA
KDQKNLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQM
LDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANE
QLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVN
GVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIK
SLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQ
QMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEK
LLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQK
ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRY
QQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGSSNSTHYQK

hide sequence

Ensembl Acc Id:

ENSRNOP00000006341 ⟸ ENSRNOT00000006341

Ensembl Acc Id:

ENSRNOP00000071329 ⟸ ENSRNOT00000081744

RefSeq Acc Id:	XP_063139619 ⟸ XM_063283549
- Peptide Label:	isoform X1
- UniProtKB:	P56536 (UniProtKB/Swiss-Prot), G3V6L4 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063139618 ⟸ XM_063283548
- Peptide Label:	isoform X1
- UniProtKB:	P56536 (UniProtKB/Swiss-Prot), G3V6L4 (UniProtKB/Swiss-Prot)

Protein Domains

Kinesin motor

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P56536-F1-model_v2	AlphaFold	P56536	1-239	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692069

Promoter ID:

EPDNEW_R2594

Type:

single initiation site

Name:

Kif5c_1

Description:

kinesin family member 5C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	35,014,515 - 35,014,575	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308539	AgrOrtholog
BioCyc Gene	G2FUF-49761	BioCyc
Ensembl Genes	ENSRNOG00000004680	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055001575	UniProtKB/Swiss-Prot
	ENSRNOG00060031970	UniProtKB/Swiss-Prot
	ENSRNOG00065008317	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000006341.8	UniProtKB/Swiss-Prot
	ENSRNOT00000081744.2	UniProtKB/TrEMBL
	ENSRNOT00055002526	UniProtKB/Swiss-Prot
	ENSRNOT00060055438	UniProtKB/Swiss-Prot
	ENSRNOT00065013194	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.850.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	6.10.250.1590	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Kinesin-like_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinesin_motor_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinesin_motor_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinesin_motor_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:311024	UniProtKB/Swiss-Prot
NCBI Gene	311024	ENTREZGENE
PANTHER	CENTROMERE PROTEIN E	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	KINESIN-LIKE PROTEIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Kinesin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Kif5c	PhenoGen
PRINTS	KINESINHEAVY	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	KINESIN_MOTOR_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	KINESIN_MOTOR_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004680	RatGTEx
	ENSRNOG00055001575	RatGTEx
	ENSRNOG00060031970	RatGTEx
	ENSRNOG00065008317	RatGTEx
SMART	KISc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2K070	ENTREZGENE, UniProtKB/TrEMBL
	G3V6L4	ENTREZGENE
	KIF5C_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	G3V6L4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Kif5c	kinesin family member 5C	Kif5c_predicted	kinesin family member 5C (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Kif5c_predicted	kinesin family member 5C (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations