Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Prxl2b | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PRXL2B mRNA | CTD | PMID:36331819 | Prxl2b | Rat | 1,1-dichloroethene | decreases expression | ISO | Prxl2b (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of PRXL2B mRNA | CTD | PMID:26682919 | Prxl2b | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of PRXL2B mRNA | CTD | PMID:32145629 | Prxl2b | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Prxl2b (Mus musculus) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether affects the expression of PRXL2B mRNA | CTD | PMID:30294300 | Prxl2b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PRXL2B mRNA | CTD | PMID:21215274 | Prxl2b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PRXL2B mRNA | CTD | PMID:33387578 | Prxl2b | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Prxl2b (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of PRXL2B mRNA | CTD | PMID:38648751 | Prxl2b | Rat | 2-palmitoylglycerol | increases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of PRXL2B mRNA | CTD | PMID:37199045 | Prxl2b | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of PRXL2B mRNA | CTD | PMID:28522335 | Prxl2b | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Prxl2b (Mus musculus) | 6480464 | bisphenol S results in increased expression of PRXL2B mRNA | CTD | PMID:39298647 | Prxl2b | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Prxl2b (Mus musculus) | 6480464 | Fenretinide results in decreased expression of PRXL2B mRNA | CTD | PMID:28973697 | Prxl2b | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of PRXL2B mRNA | CTD | PMID:31881176 | Prxl2b | Rat | acrolein | multiple interactions | ISO | PRXL2B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Prxl2b | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of PRXL2B mRNA | CTD | PMID:28959563 | Prxl2b | Rat | aflatoxin B1 | affects expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of PRXL2B protein | CTD | PMID:20106945 | Prxl2b | Rat | alpha-pinene | multiple interactions | ISO | PRXL2B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Prxl2b | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of PRXL2B mRNA | CTD | PMID:35163327 | Prxl2b | Rat | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of PRXL2B mRNA | CTD | PMID:36863539 | Prxl2b | Rat | arsenous acid | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of PRXL2B mRNA | CTD | PMID:24356939 | Prxl2b | Rat | arsenous acid | increases expression | ISO | Prxl2b (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of PRXL2B mRNA | CTD | PMID:39716349 | Prxl2b | Rat | atrazine | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Atrazine results in decreased expression of PRXL2B mRNA | CTD | PMID:22378314 | Prxl2b | Rat | Azoxymethane | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRXL2B more ... | CTD | PMID:29950665 | Prxl2b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PRXL2B mRNA | CTD | PMID:25181051 | Prxl2b | Rat | bisphenol A | decreases expression | ISO | Prxl2b (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PRXL2B mRNA | CTD | PMID:34585602|PMID:35598803 | Prxl2b | Rat | bisphenol A | increases expression | ISO | Prxl2b (Mus musculus) | 6480464 | bisphenol A results in increased expression of PRXL2B mRNA | CTD | PMID:33221593 | Prxl2b | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PRXL2B mRNA | CTD | PMID:32145629 | Prxl2b | Rat | Butylbenzyl phthalate | increases methylation | ISO | Prxl2b (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of PRXL2B promoter | CTD | PMID:28392331 | Prxl2b | Rat | cadmium atom | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression more ... | CTD | PMID:31904401 | Prxl2b | Rat | cadmium atom | multiple interactions | ISO | PRXL2B (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PRXL2B more ... | CTD | PMID:35301059 | Prxl2b | Rat | cadmium dichloride | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression more ... | CTD | PMID:31904401 | Prxl2b | Rat | cadmium dichloride | multiple interactions | ISO | PRXL2B (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PRXL2B more ... | CTD | PMID:35301059 | Prxl2b | Rat | cannabidiol | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Cannabidiol results in decreased expression of PRXL2B mRNA | CTD | PMID:33244087 | Prxl2b | Rat | cantharidin | decreases expression | ISO | Prxl2b (Mus musculus) | 6480464 | Cantharidin results in decreased expression of PRXL2B mRNA | CTD | PMID:36907384 | Prxl2b | Rat | carbon nanotube | decreases expression | ISO | Prxl2b (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of PRXL2B mRNA | CTD | PMID:25620056 | Prxl2b | Rat | clothianidin | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | clothianidin results in decreased expression of PRXL2B mRNA | CTD | PMID:31626844 | Prxl2b | Rat | copper atom | multiple interactions | ISO | PRXL2B (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of PRXL2B mRNA | CTD | PMID:20971185 | Prxl2b | Rat | copper(0) | multiple interactions | ISO | PRXL2B (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of PRXL2B mRNA | CTD | PMID:20971185 | Prxl2b | Rat | cyclosporin A | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PRXL2B mRNA | CTD | PMID:20106945|PMID:25562108|PMID:27989131 | Prxl2b | Rat | cyclosporin A | decreases methylation | ISO | PRXL2B (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of PRXL2B promoter | CTD | PMID:27989131 | Prxl2b | Rat | dextran sulfate | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRXL2B more ... | CTD | PMID:29950665 | Prxl2b | Rat | diarsenic trioxide | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of PRXL2B mRNA | CTD | PMID:24356939 | Prxl2b | Rat | diarsenic trioxide | increases expression | ISO | Prxl2b (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of PRXL2B mRNA | CTD | PMID:39716349 | Prxl2b | Rat | diazinon | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Diazinon results in decreased expression of PRXL2B mRNA | CTD | PMID:24356939 | Prxl2b | Rat | Dibutyl phosphate | affects expression | ISO | PRXL2B (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of PRXL2B mRNA | CTD | PMID:37042841 | Prxl2b | Rat | diquat | increases expression | ISO | Prxl2b (Mus musculus) | 6480464 | Diquat results in increased expression of PRXL2B mRNA | CTD | PMID:36851058 | Prxl2b | Rat | doxorubicin | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PRXL2B mRNA | CTD | PMID:29803840 | Prxl2b | Rat | gamma-hexachlorocyclohexane | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Hexachlorocyclohexane results in decreased expression of PRXL2B mRNA | CTD | PMID:24356939 | Prxl2b | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of PRXL2B mRNA | CTD | PMID:33387578 | Prxl2b | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of PRXL2B mRNA | CTD | PMID:24136188 | Prxl2b | Rat | GSK-J4 | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | GSK-J4 results in decreased expression of PRXL2B mRNA | CTD | PMID:29301935 | Prxl2b | Rat | inulin | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PRXL2B mRNA | CTD | PMID:36331819 | Prxl2b | Rat | levofloxacin | increases expression | EXP | | 6480464 | Levofloxacin results in increased expression of PRXL2B mRNA | CTD | PMID:24136188 | Prxl2b | Rat | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of PRXL2B mRNA | CTD | PMID:24136188 | Prxl2b | Rat | nitrofen | increases expression | EXP | | 6480464 | nitrofen results in increased expression of PRXL2B mRNA | CTD | PMID:26720608 | Prxl2b | Rat | okadaic acid | increases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of PRXL2B mRNA | CTD | PMID:38832940 | Prxl2b | Rat | ozone | multiple interactions | ISO | PRXL2B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Prxl2b | Rat | p-toluidine | increases expression | EXP | | 6480464 | 4-toluidine results in increased expression of PRXL2B mRNA | CTD | PMID:27638505 | Prxl2b | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PRXL2B mRNA | CTD | PMID:33387578 | Prxl2b | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PRXL2B mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Prxl2b | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of PRXL2B mRNA | CTD | PMID:35163327 | Prxl2b | Rat | phorbol 13-acetate 12-myristate | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression more ... | CTD | PMID:31904401 | Prxl2b | Rat | pioglitazone | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Pioglitazone results in decreased expression of PRXL2B mRNA | CTD | PMID:30031879 | Prxl2b | Rat | resveratrol | multiple interactions | ISO | PRXL2B (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of PRXL2B mRNA | CTD | PMID:23557933 | Prxl2b | Rat | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of PRXL2B mRNA | CTD | PMID:32721576 | Prxl2b | Rat | sodium arsenate | increases expression | ISO | Prxl2b (Mus musculus) | 6480464 | sodium arsenate results in increased expression of PRXL2B mRNA | CTD | PMID:39847705 | Prxl2b | Rat | sodium arsenite | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PRXL2B mRNA | CTD | PMID:38568856 | Prxl2b | Rat | sodium arsenite | increases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PRXL2B mRNA | CTD | PMID:34032870 | Prxl2b | Rat | sodium fluoride | decreases expression | ISO | Prxl2b (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of PRXL2B mRNA | CTD | PMID:27862939 | Prxl2b | Rat | sunitinib | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of PRXL2B mRNA | CTD | PMID:31533062 | Prxl2b | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of PRXL2B mRNA | CTD | PMID:31150632 | Prxl2b | Rat | tetrachloromethane | decreases expression | ISO | Prxl2b (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of PRXL2B mRNA | CTD | PMID:31919559 | Prxl2b | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PRXL2B mRNA | CTD | PMID:23411599|PMID:34492290 | Prxl2b | Rat | thiram | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Thiram results in decreased expression of PRXL2B mRNA | CTD | PMID:38568856 | Prxl2b | Rat | titanium dioxide | multiple interactions | ISO | Prxl2b (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRXL2B more ... | CTD | PMID:29950665 | Prxl2b | Rat | toluene | decreases expression | EXP | | 6480464 | Toluene results in decreased expression of PRXL2B mRNA | CTD | PMID:22967744 | Prxl2b | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PRXL2B mRNA | CTD | PMID:33387578 | Prxl2b | Rat | valproic acid | increases methylation | ISO | PRXL2B (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PRXL2B gene | CTD | PMID:29154799 | Prxl2b | Rat | valproic acid | decreases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PRXL2B mRNA | CTD | PMID:29154799 | Prxl2b | Rat | zoledronic acid | increases expression | ISO | PRXL2B (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of PRXL2B mRNA | CTD | PMID:24714768 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||





















