Ralgapa2 (Ral GTPase activating protein catalytic subunit alpha 2) - Rat Genome Database

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Pathways
Gene: Ralgapa2 (Ral GTPase activating protein catalytic subunit alpha 2) Rattus norvegicus
Analyze
Symbol: Ralgapa2
Name: Ral GTPase activating protein catalytic subunit alpha 2
RGD ID: 1308023
Description: Enables GTPase activator activity and protein heterodimerization activity. Involved in activation of GTPase activity. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 250 kDa substrate of Akt; AS250; LOC296211; p220; Ral GTPase activating protein catalytic alpha subunit 2; Ral GTPase activating protein, alpha subunit 2 (catalytic); Ral GTPase-activating protein alpha subunit 2; ral GTPase-activating protein subunit alpha-2; RGD1308023; similar to CG5521-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83154,112,005 - 154,392,070 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3154,112,014 - 154,392,138 (-)EnsemblGRCr8
mRatBN7.23133,658,725 - 133,938,821 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)EnsemblmRatBN7.2
Rnor_6.03140,451,850 - 140,728,305 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)Ensemblrn6Rnor6.0
Rnor_5.03146,870,901 - 147,146,723 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43134,867,846 - 135,145,583 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3132,526,330 - 132,803,310 (-)NCBICelera
RGSC_v3.13134,893,509 - 134,996,492 (-)NCBI
Cytogenetic Map3q41NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2,5-hexanedione  (EXP)
2-hydroxypropanoic acid  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
FR900359  (ISO)
hexadecanoic acid  (ISO)
leflunomide  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
Monobutylphthalate  (EXP)
N,N-diethyl-m-toluamide  (EXP)
nickel sulfate  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
potassium chromate  (ISO)
propanal  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetraphene  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
cytosol  (IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases. Shirakawa R, etal., J Biol Chem. 2009 Aug 7;284(32):21580-8. doi: 10.1074/jbc.M109.012112. Epub 2009 Jun 11.
Additional References at PubMed
PMID:15057822   PMID:15632090   PMID:16490346   PMID:21148297   PMID:22664934  


Genomics

Comparative Map Data
Ralgapa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83154,112,005 - 154,392,070 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3154,112,014 - 154,392,138 (-)EnsemblGRCr8
mRatBN7.23133,658,725 - 133,938,821 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)EnsemblmRatBN7.2
Rnor_6.03140,451,850 - 140,728,305 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)Ensemblrn6Rnor6.0
Rnor_5.03146,870,901 - 147,146,723 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43134,867,846 - 135,145,583 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3132,526,330 - 132,803,310 (-)NCBICelera
RGSC_v3.13134,893,509 - 134,996,492 (-)NCBI
Cytogenetic Map3q41NCBI
RALGAPA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382020,389,530 - 20,712,644 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2020,389,530 - 20,712,644 (-)Ensemblhg38GRCh38
GRCh372020,370,174 - 20,693,287 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362020,321,411 - 20,641,266 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2020,447,485 - 20,767,346 (-)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2020,333,630 - 20,656,842 (-)NCBIHuRef
CHM1_12020,370,712 - 20,693,651 (-)NCBICHM1_1
T2T-CHM13v2.02020,448,061 - 20,771,350 (-)NCBIT2T-CHM13v2.0
Ralgapa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392146,079,326 - 146,354,174 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2146,081,799 - 146,354,264 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382146,239,876 - 146,512,254 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2146,239,879 - 146,512,344 (-)Ensemblmm10GRCm38
MGSCv372146,067,032 - 146,337,740 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362146,120,893 - 146,203,447 (-)NCBIMGSCv36mm8
Celera2147,474,453 - 147,748,942 (-)NCBICelera
Cytogenetic Map2G1NCBI
cM Map271.33NCBI
Ralgapa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541528,414,386 - 28,663,485 (-)Ensembl
ChiLan1.0NW_00495541528,414,856 - 28,663,485 (-)NCBIChiLan1.0ChiLan1.0
RALGAPA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,268,175 - 21,594,631 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12021,267,629 - 21,591,448 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02020,338,629 - 20,662,926 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12020,299,568 - 20,625,458 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2020,299,638 - 20,625,443 (-)EnsemblpanPan2panpan1.1
RALGAPA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,665,950 - 2,992,779 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,676,461 - 2,989,864 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha242,694,032 - 3,021,021 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0243,073,282 - 3,400,603 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl243,083,818 - 3,398,194 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1242,670,124 - 2,996,986 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0242,773,127 - 3,100,047 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0243,051,017 - 3,378,081 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ralgapa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640151,333,758 - 151,615,951 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049372858,016 - 105,025 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049372857,705 - 105,200 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGAPA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1728,408,099 - 28,679,231 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11728,408,096 - 28,679,231 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21732,010,888 - 32,135,505 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGAPA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1249,381,251 - 49,704,946 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl249,465,647 - 49,645,287 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660784,168,451 - 4,496,449 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralgapa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474120,885,215 - 21,171,787 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474120,889,913 - 21,171,787 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ralgapa2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15125,865,805 - 126,136,191 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ralgapa2
1793 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:16
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000015637
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
D3Rat215  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83154,367,513 - 154,367,746 (+)Marker Load Pipeline
Rnor_6.03140,703,784 - 140,704,003NCBIRnor6.0
Rnor_5.03147,122,482 - 147,122,701UniSTSRnor5.0
RGSC_v3.43135,120,846 - 135,121,076RGDRGSC3.4
RGSC_v3.43135,120,844 - 135,121,076UniSTSRGSC3.4
Celera3132,778,800 - 132,779,032UniSTS
RGSC_v3.13135,026,419 - 135,026,649RGD
SHRSP x BN Map364.1499RGD
SHRSP x BN Map364.1499UniSTS
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001421313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000015637   ⟹   ENSRNOP00000015637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3154,132,465 - 154,392,089 (-)Ensembl
mRatBN7.2 Ensembl3133,678,482 - 133,938,727 (-)Ensembl
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094218   ⟹   ENSRNOP00000080653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3154,112,014 - 154,392,089 (-)Ensembl
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106826   ⟹   ENSRNOP00000093785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3154,112,014 - 154,392,138 (-)Ensembl
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113019   ⟹   ENSRNOP00000084183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3154,112,014 - 154,392,089 (-)Ensembl
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000125212   ⟹   ENSRNOP00000102411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3154,112,014 - 154,392,089 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000148463   ⟹   ENSRNOP00000107754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3154,112,014 - 154,392,089 (-)Ensembl
RefSeq Acc Id: NM_001421313   ⟹   NP_001408242
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,047 (-)NCBI
mRatBN7.23133,658,725 - 133,938,797 (-)NCBI
RefSeq Acc Id: XM_017592238   ⟹   XP_017447727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,070 (-)NCBI
mRatBN7.23133,661,955 - 133,938,820 (-)NCBI
Rnor_6.03140,451,850 - 140,728,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106622   ⟹   XP_038962550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,209,810 - 154,392,070 (-)NCBI
mRatBN7.23133,756,535 - 133,938,821 (-)NCBI
RefSeq Acc Id: XM_039106623   ⟹   XP_038962551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,988 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XM_039106624   ⟹   XP_038962552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,988 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XM_063283347   ⟹   XP_063139417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,070 (-)NCBI
RefSeq Acc Id: XM_063283348   ⟹   XP_063139418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,069 (-)NCBI
RefSeq Acc Id: XM_063283349   ⟹   XP_063139419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,069 (-)NCBI
RefSeq Acc Id: XM_063283350   ⟹   XP_063139420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,378,785 (-)NCBI
RefSeq Acc Id: XM_063283352   ⟹   XP_063139422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,292,812 (-)NCBI
RefSeq Acc Id: XM_063283353   ⟹   XP_063139423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,283,873 (-)NCBI
RefSeq Acc Id: XR_005502527
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,230,860 - 154,392,069 (-)NCBI
mRatBN7.23133,773,811 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_005502528
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,980 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_005502529
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,980 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_010064588
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,231,124 - 154,392,069 (-)NCBI
RefSeq Acc Id: XP_017447727   ⟸   XM_017592238
- Peptide Label: isoform X1
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015637   ⟸   ENSRNOT00000015637
RefSeq Acc Id: XP_038962550   ⟸   XM_039106622
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038962552   ⟸   XM_039106624
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038962551   ⟸   XM_039106623
- Peptide Label: isoform X7
Ensembl Acc Id: ENSRNOP00000093785   ⟸   ENSRNOT00000106826
Ensembl Acc Id: ENSRNOP00000080653   ⟸   ENSRNOT00000094218
Ensembl Acc Id: ENSRNOP00000084183   ⟸   ENSRNOT00000113019
RefSeq Acc Id: NP_001408242   ⟸   NM_001421313
- UniProtKB: P86411 (UniProtKB/Swiss-Prot),   A0A8I6G4U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139417   ⟸   XM_063283347
- Peptide Label: isoform X2
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063139418   ⟸   XM_063283348
- Peptide Label: isoform X3
- UniProtKB: P86411 (UniProtKB/Swiss-Prot),   A0A8I6AGG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139419   ⟸   XM_063283349
- Peptide Label: isoform X4
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063139420   ⟸   XM_063283350
- Peptide Label: isoform X5
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063139422   ⟸   XM_063283352
- Peptide Label: isoform X9
- UniProtKB: A6K791 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139423   ⟸   XM_063283353
- Peptide Label: isoform X10
- UniProtKB: A6K791 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102411   ⟸   ENSRNOT00000125212
Ensembl Acc Id: ENSRNOP00000107754   ⟸   ENSRNOT00000148463
Protein Domains
Rap-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P86411-F1-model_v2 AlphaFold P86411 1-1872 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308023 AgrOrtholog
BioCyc Gene G2FUF-47571 BioCyc
Ensembl Genes ENSRNOG00000036964 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000094218 ENTREZGENE
  ENSRNOT00000106826 ENTREZGENE
  ENSRNOT00000113019.1 UniProtKB/Swiss-Prot
  ENSRNOT00000125212 ENTREZGENE
Gene3D-CATH 3.40.50.11210 UniProtKB/Swiss-Prot
InterPro ARM-type_fold UniProtKB/Swiss-Prot
  Rap/Ran-GAP_sf UniProtKB/Swiss-Prot
  Rap_GAP_dom UniProtKB/Swiss-Prot
  RGPA/RALGAPB_N UniProtKB/Swiss-Prot
  Tuberin/Ral-act_asu UniProtKB/Swiss-Prot
NCBI Gene 296211 ENTREZGENE
PANTHER PTHR10063 UniProtKB/Swiss-Prot
  RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-2 UniProtKB/Swiss-Prot
Pfam RALGAPB_N UniProtKB/Swiss-Prot
  Rap_GAP UniProtKB/Swiss-Prot
PhenoGen Ralgapa2 PhenoGen
PROSITE RAPGAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000036964 RatGTEx
Superfamily-SCOP SSF111347 UniProtKB/Swiss-Prot
  SSF48371 UniProtKB/Swiss-Prot
UniProt A0A8I6AGG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G4U3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LM31_RAT UniProtKB/TrEMBL
  A0ABK0LPB7_RAT UniProtKB/TrEMBL
  A6K791 ENTREZGENE, UniProtKB/TrEMBL
  D3ZKI6_RAT UniProtKB/TrEMBL
  P86411 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Ralgapa2  Ral GTPase activating protein catalytic subunit alpha 2  Ralgapa2  Ral GTPase activating protein catalytic alpha subunit 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Ralgapa2  Ral GTPase activating protein catalytic alpha subunit 2  Ralgapa2  Ral GTPase activating protein, alpha subunit 2 (catalytic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-10 Ralgapa2  Ral GTPase activating protein, alpha subunit 2 (catalytic)  RGD1308023  similar to CG5521-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1308023  similar to CG5521-PA   RGD1308023_predicted  similar to CG5521-PA (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308023_predicted  similar to CG5521-PA (predicted)  LOC296211_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296211_predicted  similar to CG5521-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL