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Gene: Glrx2 (glutaredoxin 2) Rattus norvegicus

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Symbol:

Glrx2

Name:

glutaredoxin 2

RGD ID:

1307950

Description:

Predicted to enable protein-disulfide reductase activity. Involved in cellular response to superoxide. Located in dendrite; mitochondrial matrix; and neuronal cell body. Orthologous to human GLRX2 (glutaredoxin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

glutaredoxin 2 (thioltransferase); glutaredoxin-2, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GLRX2 (glutaredoxin 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Glrx2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Glrx2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GLRX2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GLRX2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Glrx2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GLRX2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GLRX2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Glrx2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Glrx2 (glutaredoxin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GLRX2 (glutaredoxin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GLRX2 (glutaredoxin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Glrx2 (glutaredoxin 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	glrx2 (glutaredoxin 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	glrx2 (glutaredoxin 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GRX1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GRX1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector)
Drosophila melanogaster (fruit fly):	Grx1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Grx1t	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Grx1t	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	glrx-21	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	glrx-21	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GRX2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GRX2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector)
Caenorhabditis elegans (roundworm):	glrx-22	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	glrx-22	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	glrx2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	glrx2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	58,032,199 - 58,055,061 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	58,032,401 - 58,043,150 (+)	Ensembl				GRCr8
mRatBN7.2	13	55,481,875 - 55,504,737 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	55,482,694 - 55,492,831 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	58,049,631 - 58,073,274 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	59,317,533 - 59,340,392 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	56,602,199 - 56,625,867 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	60,529,057 - 60,552,115 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	60,529,932 - 60,537,916 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	65,517,621 - 65,540,676 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	57,567,017 - 57,589,873 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	55,569,577 - 55,592,422 (+)	NCBI		Celera
RGSC_v3.1	13	57,581,096 - 57,603,951 (+)	NCBI
Cytogenetic Map	13	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

all-trans-retinoic acid (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsane (EXP)

arsenic atom (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

Butylbenzyl phthalate (ISO)

cannabidiol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

cisplatin (ISO)

clotrimazole (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) chloride (ISO)

crocidolite asbestos (ISO)

Diallyl sulfide (EXP)

dibenzo[a,l]pyrene (ISO)

Dibutyl phosphate (ISO)

disulfiram (ISO)

diuron (EXP)

dorsomorphin (ISO)

elemental selenium (EXP)

finasteride (EXP)

flutamide (EXP)

genistein (ISO)

hexane (EXP)

isotretinoin (ISO)

mercury dibromide (ISO)

Mesaconitine (EXP)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylene blue (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

nefazodone (EXP)

nimesulide (EXP)

okadaic acid (ISO)

ozone (ISO)

panobinostat (ISO)

paraquat (ISO)

phenobarbital (EXP)

phenylmercury acetate (ISO)

phlorizin (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

S-butyl-DL-homocysteine (S,R)-sulfoximine (EXP)

SB 431542 (ISO)

selenium atom (EXP)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

toluene (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to superoxide (IEP)

Cellular Component

dendrite (IDA)

mitochondrial matrix (IDA)

mitochondrion (IBA,IEA,ISO)

neuronal cell body (IDA)

nucleoplasm (ISO)

nucleus (IEA,ISO)

Molecular Function

2 iron, 2 sulfur cluster binding (IEA)

iron-sulfur cluster binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

protein-disulfide reductase activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Thioredoxin and glutaredoxin system proteins-immunolocalization in the rat central nervous system.	Aon-Bertolino ML, etal., Biochim Biophys Acta. 2011 Jan;1810(1):93-110. Epub 2010 Jul 8.
2.	Aging-dependent changes in rat heart mitochondrial glutaredoxins-Implications for redox regulation.	Gao XH, etal., Redox Biol. 2013 Nov 12;1(1):586-98. doi: 10.1016/j.redox.2013.10.010. eCollection 2013.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria?	Pai HV, etal., Antioxid Redox Signal. 2007 Nov;9(11):2027-33.
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11297543	PMID:11397793	PMID:15057822	PMID:15489334	PMID:18614015	PMID:20929858	PMID:23872354	PMID:25735211

Genomics

Comparative Map Data

Glrx2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	58,032,199 - 58,055,061 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	58,032,401 - 58,043,150 (+)	Ensembl				GRCr8
mRatBN7.2	13	55,481,875 - 55,504,737 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	55,482,694 - 55,492,831 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	58,049,631 - 58,073,274 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	59,317,533 - 59,340,392 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	56,602,199 - 56,625,867 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	60,529,057 - 60,552,115 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	60,529,932 - 60,537,916 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	65,517,621 - 65,540,676 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	57,567,017 - 57,589,873 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	55,569,577 - 55,592,422 (+)	NCBI		Celera
RGSC_v3.1	13	57,581,096 - 57,603,951 (+)	NCBI
Cytogenetic Map	13	q21	NCBI

GLRX2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	193,096,465 - 193,106,114 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	193,090,866 - 193,106,114 (-)	Ensembl			hg38	GRCh38
GRCh37	1	193,065,595 - 193,075,244 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	191,332,223 - 191,341,867 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	189,797,256 - 189,806,213	NCBI
Celera	1	166,175,205 - 166,184,851 (-)	NCBI		Celera
Cytogenetic Map	1	q31.2	NCBI
HuRef	1	164,301,400 - 164,311,051 (-)	NCBI		HuRef
CHM1_1	1	194,487,507 - 194,497,156 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	192,443,673 - 192,453,323 (-)	NCBI		T2T-CHM13v2.0

Glrx2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	143,614,787 - 143,625,416 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	143,592,076 - 143,625,414 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	143,739,224 - 143,749,678 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	143,716,338 - 143,749,676 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	145,586,479 - 145,596,808 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	145,501,567 - 145,511,896 (+)	NCBI		MGSCv36	mm8
Celera	1	146,314,372 - 146,324,701 (+)	NCBI		Celera
Cytogenetic Map	1	F	NCBI
cM Map	1	62.53	NCBI

Glrx2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	30,497,562 - 30,509,340 (-)	Ensembl
ChiLan1.0	NW_004955406	30,497,562 - 30,506,463 (-)	NCBI	ChiLan1.0	ChiLan1.0

GLRX2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	56,686,397 - 56,696,287 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	56,350,292 - 56,360,174 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	168,555,858 - 168,565,949 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	172,848,858 - 172,859,970 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	172,849,013 - 172,859,062 (-)	Ensembl			panPan2	panpan1.1

GLRX2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	5,963,800 - 5,971,673 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	5,964,039 - 5,971,676 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	6,060,945 - 6,068,683 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	5,980,501 - 5,988,282 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	5,980,991 - 5,988,283 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	5,979,964 - 5,987,654 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	6,345,372 - 6,353,229 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	6,574,000 - 6,582,001 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Glrx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	80,810,029 - 80,819,376 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936638	1,325,586 - 1,334,016 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936638	1,325,076 - 1,333,994 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GLRX2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	10	679,305 - 689,890 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

GLRX2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	36,318,894 - 36,328,567 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	36,319,637 - 36,328,417 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	37,267,701 - 37,276,856 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Glrx2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624814	482,545 - 509,507 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624814	481,981 - 505,052 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Glrx2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	23,657,878 - 23,666,318 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Glrx2
136 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	1160
Count of miRNA genes:	271
Interacting mature miRNAs:	331
Transcripts:	ENSRNOT00000004558, ENSRNOT00000060062
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	48749814	87285480	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	24853925	69853925	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	39968211	83286298	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	17468282	62468282	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37087983	82087983	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	40983585	85983585	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	26244808	71244808	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	33794096	78794096	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	34834947	79834947	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	33794096	60914504	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	39814726	84814726	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	39968211	84968211	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	26244808	71244808	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	38286298	83286298	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	17711336	62711336	Rat

Markers in Region

D13Rat150

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	58,031,414 - 58,031,541 (+)	Marker Load Pipeline
mRatBN7.2	13	55,481,090 - 55,481,217 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	60,528,276 - 60,528,402	NCBI	Rnor6.0
Rnor_5.0	13	65,516,837 - 65,516,963	UniSTS	Rnor5.0
RGSC_v3.4	13	57,566,232 - 57,566,359	RGD	RGSC3.4
RGSC_v3.4	13	57,566,233 - 57,566,359	UniSTS	RGSC3.4
Celera	13	55,568,793 - 55,568,919	UniSTS
RGSC_v3.1	13	57,580,312 - 57,580,439	RGD
SHRSP x BN Map	13	20.8298	UniSTS
SHRSP x BN Map	13	20.8298	RGD
Cytogenetic Map	13	q13	UniSTS

RH131213

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	55,496,129 - 55,496,286 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	60,543,508 - 60,543,664	NCBI	Rnor6.0
Rnor_5.0	13	65,532,069 - 65,532,225	UniSTS	Rnor5.0
RGSC_v3.4	13	57,581,272 - 57,581,428	UniSTS	RGSC3.4
Celera	13	55,583,818 - 55,583,974	UniSTS
Cytogenetic Map	13	q13	UniSTS

AI645710

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	55,490,587 - 55,490,670 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	60,537,773 - 60,537,855	NCBI	Rnor6.0
Rnor_5.0	13	65,526,334 - 65,526,416	UniSTS	Rnor5.0
RGSC_v3.4	13	57,575,730 - 57,575,812	UniSTS	RGSC3.4
Celera	13	55,578,276 - 55,578,358	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH128827

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	55,494,674 - 55,494,863 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	60,542,053 - 60,542,241	NCBI	Rnor6.0
Rnor_5.0	13	65,530,614 - 65,530,802	UniSTS	Rnor5.0
RGSC_v3.4	13	57,579,817 - 57,580,005	UniSTS	RGSC3.4
Celera	13	55,582,363 - 55,582,551	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH133629

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	55,496,596 - 55,496,781 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	60,543,975 - 60,544,159	NCBI	Rnor6.0
Rnor_5.0	13	65,532,536 - 65,532,720	UniSTS	Rnor5.0
RGSC_v3.4	13	57,581,739 - 57,581,923	UniSTS	RGSC3.4
Celera	13	55,584,285 - 55,584,469	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH134315

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	55,492,552 - 55,492,755 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	60,539,738 - 60,539,940	NCBI	Rnor6.0
Rnor_5.0	13	65,528,299 - 65,528,501	UniSTS	Rnor5.0
RGSC_v3.4	13	57,577,695 - 57,577,897	UniSTS	RGSC3.4
Celera	13	55,580,241 - 55,580,443	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH143907

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	55,500,894 - 55,501,105 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	60,548,273 - 60,548,483	NCBI	Rnor6.0
Rnor_5.0	13	65,536,834 - 65,537,044	UniSTS	Rnor5.0
RGSC_v3.4	13	57,586,037 - 57,586,247	UniSTS	RGSC3.4
Celera	13	55,588,586 - 55,588,796	UniSTS
Cytogenetic Map	13	q21	UniSTS
Cytogenetic Map	13	q13	UniSTS

BE117735

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	55,494,903 - 55,495,065 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	60,542,282 - 60,542,443	NCBI	Rnor6.0
Rnor_5.0	13	65,530,843 - 65,531,004	UniSTS	Rnor5.0
RGSC_v3.4	13	57,580,046 - 57,580,207	UniSTS	RGSC3.4
Celera	13	55,582,592 - 55,582,753	UniSTS
Cytogenetic Map	13	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001394170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001394171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001394172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_172084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010056897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010056898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_358962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_595464	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213555	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000060062 ⟹ ENSRNOP00000056811

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	58,032,991 - 58,043,150 (+)	Ensembl
mRatBN7.2 Ensembl	13	55,482,694 - 55,492,831 (+)	Ensembl
Rnor_6.0 Ensembl	13	60,529,932 - 60,537,916 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106322 ⟹ ENSRNOP00000096477

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	58,032,401 - 58,041,081 (+)	Ensembl
mRatBN7.2 Ensembl	13	55,482,728 - 55,492,822 (+)	Ensembl

RefSeq Acc Id:

NM_001394170 ⟹ NP_001381099

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,033,007 - 58,043,157 (+)	NCBI
mRatBN7.2	13	55,482,683 - 55,492,833 (+)	NCBI

RefSeq Acc Id:

NM_001394171 ⟹ NP_001381100

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,033,878 - 58,043,157 (+)	NCBI
mRatBN7.2	13	55,483,554 - 55,492,833 (+)	NCBI

RefSeq Acc Id:

NM_001394172 ⟹ NP_001381101

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,770 - 58,043,157 (+)	NCBI
mRatBN7.2	13	55,482,446 - 55,492,833 (+)	NCBI

RefSeq Acc Id:

NR_172084

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,199 - 58,055,055 (+)	NCBI
mRatBN7.2	13	55,481,875 - 55,504,731 (+)	NCBI

RefSeq Acc Id:

XM_006249955 ⟹ XP_006250017

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,459 - 58,043,154 (+)	NCBI
mRatBN7.2	13	55,482,539 - 55,492,833 (+)	NCBI
Rnor_6.0	13	60,529,734 - 60,540,015 (+)	NCBI
Rnor_5.0	13	65,517,621 - 65,540,676 (+)	NCBI

Sequence:

show sequence

GCAGAGGATGCGAATTTGGAGGCTCGTGGGCGCGCCGGCTCGTGGGCGTGCGGAGACAGGGTAG
CCAGGAAGAGCGGCGAGCCCGGCGGCCGCGCGGGCAGCCCGGTGGGGCGGAGCGAGGCAGCCGG
AGGGGCGGGCTCCCGGCGTCGTGGTCGCGCTCGCGTGCTCCGTTCCCTGCGGCTGCCCGGACCC
TTGGCCATGTCCTGGTACCGCGCGGCTTCGGTGGGGAGGCGGCTGGTGGCGAGCGGGAGGATCT
TGGCGGGGCGGCGCGGCGCGGCTGGAGCTGCGGGCTCGGGAATGGGAAACAGCACATCCTCGTT
TTGGGGGAAGTCAGCCACTACTCCTGTGAACCAGATCCAAGAAACAATTTCTAATAATTGTGTG
GTGATTTTCTCAAAATCATCCTGCTCTTACTGTTCAATGGCCAAGAAGATTTTCCATGACATGA
ATGTCAACTATAAAGTCGTGGAGTTGGATATGGTGGAATATGGTAGCCAGTTTCAAGAGGCTCT
TTACAAGATGACTGGAGAAAGAACTGTTCCCAGGATATTTGTGAATGGAATATTTATCGGAGGT
GCGGCCGACACTCACAGGCTTCACAAAGAAGGGAAATTGCTGCCTCTGGTTCACCAGTGCTATT
TAAACAAAAGCAAGAGGAAAGACGTCGAATGACGTGGCTAGTCGCCGTACCAGTAAACCGTCCT
GATGCAGCAAGGAAATCCTCACTAGATGCTGGCACTTTAACCTCAACATCCCAACCTATGAACT
ATAAGAAGTCCTTCTCATCTTCATAAATTACTTAGTCTCAGGTATTCTGTCTGAGTAGCACAGA
TAGATTGTCCCTAAAGTCCCTTCTGTTATCTTACTATTTTCTAACTAGGAAGACACTGTTTAAA
CTGATTACATTTCAGATAAACTTAGCGAACAGGATTAACTTTTAAGAAGTATTATTTGAAAGAA
TTGAAAACATTTTCAATACTTTACTAATCTGGTCATATTTATAGCCTCTGGTCAAGAATATTTT
AAGTGCCTAAGAAGTAATGCATTTCCTAGTAGATTCCGAGAGTCAGGTTGGAAAGATTATTAAA
TGCTGAGCCTATCTCAGAAATAGGAAGAACATGGACTTCCCGAGTAAGTGCTTCAGCTTTCTGG
TCAAGATGGACTAAGGAATCATGGAGAATTTGGAGGGAGACAGTGGCTTGCTGTCGGTGACATT
TCCTACATGGACTTCAACTGCATTTTGAATACCTTGATACAGTTGAGAAGTTAAGTTCTCCTGA
TATTTCTTTCTTTTAAGTTGTCATGTTGGTAGGGAAGGAAAATGGTGTATTTCTACTCCTTTAT
TTTACATTTTATCATGAAAATTGTATAATTTTGCTATGCTGTAAAATTCACATTAGAGATTAGA
GGAAGTCTGTTATGCATAAGAAAGGTAAAATTGTTACTCTTGTCACTAGTAATCTTATTAGGAT
ATAAGATTAGGTTGCTTAAATGCATAGCCCACCAACCAAGTAATATGGTATTTGGCTTTGAGGA
ATTTTTGTGGTATTCAGACTCAGACCCAGGGCCTGAATATTAGGCAGGCGCCTGACCACTGAAC
TATACAACTAATCCTTAAGAAGGATGTTCCAACAGCTCTACCTAGGCTTGTGGAAAACAAGAGG
ATGTGTAGTACTTAATTCTTAGGGTCCGATGTTAAAATAATCCAGCTCTTTAAAAAGCCTTAGC
AGAAGGCTCAAGAATATGGAAGGTAACAGGGTATCTTGATTTTCAATTATACGTTTAAGGAATA
AAGAAATAAACTCTTCCAATGATTGCCTAATA

hide sequence

RefSeq Acc Id:

XM_008769526 ⟹ XP_008767748

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,459 - 58,041,181 (+)	NCBI
mRatBN7.2	13	55,482,542 - 55,492,833 (+)	NCBI
Rnor_6.0	13	60,529,740 - 60,538,042 (+)	NCBI

Sequence:

show sequence

GATGCGAATTTGGAGGCTCGTGGGCGCGCCGGCTCGTGGGCGTGCGGAGACAGGGTAGCCAGGA
AGAGCGGCGAGCCCGGCGGCCGCGCGGGCAGCCCGGTGGGGCGGAGCGAGGCAGCCGGAGGGGC
GGGCTCCCGGCGTCGTGGTCGCGCTCGCGTGCTCCGTTCCCTGCGGCTGCCCGGACCCTTGGCC
ATGTCCTGAATGGGAAACAGCACATCCTCGTTTTGGGGGAAGTCAGCCACTACTCCTGTGAACC
AGATCCAAGAAACAATTTCTAATAATTGTGTGGTGATTTTCTCAAAATCATCCTGCTCTTACTG
TTCAATGGCCAAGAAGATTTTCCATGACATGAATGTCAACTATAAAGTCGTGGAGTTGGATATG
GTGGAATATGGTAGCCAGTTTCAAGAGGCTCTTTACAAGATGACTGGAGAAAGAACTGTTCCCA
GGATATTTGTGAATGGAATATTTATCGGAGGTGCGGCCGACACTCACAGGCTTCACAAAGAAGG
GAAATTGCTGCCTCTGGTTCACCAGTGCTATTTAAACAAAAGCAAGAGGAAAGACGTCGAATGA
CGTGGCTAGTCGCCGTACCAGTAAACGTTAGTGCAGTCATAACCTTTCACTTGAGGATGTTTTC
AGTGTGTGGATTGCCCTCATAAAGATGAAAATAATGAACAATAAATTGCCATGGACCCCTCA

hide sequence

RefSeq Acc Id:

XM_039090229 ⟹ XP_038946157

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,459 - 58,041,181 (+)	NCBI
mRatBN7.2	13	55,482,079 - 55,492,833 (+)	NCBI

RefSeq Acc Id:

XM_039090231 ⟹ XP_038946159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,459 - 58,041,181 (+)	NCBI
mRatBN7.2	13	55,482,542 - 55,492,833 (+)	NCBI

RefSeq Acc Id:

XM_063271953 ⟹ XP_063128023

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,201 - 58,041,181 (+)	NCBI

RefSeq Acc Id:

XM_063271954 ⟹ XP_063128024

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,033,873 - 58,043,154 (+)	NCBI

RefSeq Acc Id:

XR_001840761

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,459 - 58,055,061 (+)	NCBI
mRatBN7.2	13	55,482,539 - 55,504,737 (+)	NCBI
Rnor_6.0	13	60,529,734 - 60,552,115 (+)	NCBI

Sequence:

show sequence

GCAGAGGATGCGAATTTGGAGGCTCGTGGGCGCGCCGGCTCGTGGGCGTGCGGAGACAGGGTAG
CCAGGAAGAGCGGCGAGCCCGGCGGCCGCGCGGGCAGCCCGGTGGGGCGGAGCGAGGCAGCCGG
AGGGGCGGGCTCCCGGCGTCGTGGTCGCGCTCGCGTGCTCCGTTCCCTGCGGCTGCCCGGACCC
TTGGCCATGTCCTGGTACCGCGCGGCTTCGGTGGGGAGGCGGCTGGTGGCGAGCGGGAGGATCT
TGGCGGGGCGGCGCGGCGCGGCTGGAGCTGCGGGCTCGGGAATGGGAAACAGCACATCCTCGTT
TTGGGGGAAGTCAGCCACTACTCCTGTGAACCAGATCCAAGAAACAATTTCTAATAATTGTGTG
GTGATTTTCTCAAAATCATCCTGCTCTTACTGTTCAATGGCCAAGAAGATTTTCCATGACATGA
ATGTCAACTATAAAGTCGTGGAGTTGGATATGGTGGAATATGGTAGCCAGTTTCAAGAGGCTCT
TTACAAGATGACTGGAGAAAGAACTGTTCCCAGGATATTTGTGAATGGAATATTTATCGGAGGT
GCGGCCGACACTCACAGGCTTCACAAAGAAGGGAAATTGCTGCCTCTGGTTCACCAGTGCTATT
TAAACAAAAGCAAGAGGAAAGACGTCGAATGACGTGGCTAGTCGCCGTACCAGTAAACCGTCCT
GATGCAGCAAGGAAATCCTCACTAGATGCTGGCACTTTAACCTCAACATCCCAACCTATGAACT
ATAAGAAGTCCTTCTCATCTTCATAAATTACTTAGTCTCAGGGAATAATGACATCCTATCATTT
ATAATCAAAAACGAAGTTTGAACTTGTAATGAAAGGCCTCCTTTCCAGTTTCAATGTCAGAATA
TAGAGTCACAGCACTGGGGAGCACGGGCTGGGGAGATGGCTCGGTGGGAAAAGGTCCTTGCTGC
CAGCCACTCTGAACTCAATCCCTGGAATCCACAAGGTGGAAGGACAGGATGAGACCTGTATTGT
CTATCTTCTGAGGGTTCCCTTCCCCAGGGGCCAATGGCATTCATACAAACAAACTAACAAAAGC
CATAACTCAAGACAAGAAACTTCTGAGATCTGGAATCTACAGCACTCTCCTAGGCAGATAAATA
CTTCTCATTTACTAAACGAGGAATGAAGCAGAATAGTGGAGATGTGCTGCCTTCCTACGTGGTG
AGGGAACCTGGGTTGAGAACTGAACCTTACTACTGCCCTTTACTCATTTCTTGAGTAAGGAATT
CATTTTAGCCAGGTTTTGTTTTTGTTTTTTCCTAACCATCACGTACTTCTGCATATACTACCAA
CATTTAATCTTGTTATAACATCTGGCAGCTCAGATCTGATCCTTCCTTACACACGCCCCTTTTC
AGCATGTGTAAAACTTTGCGTTATAAACTTCTCTTTGGATATAAAGTGATAAATGTCACATAAG
TGAAA

hide sequence

RefSeq Acc Id:

XR_010056897

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,032,459 - 58,054,264 (+)	NCBI

RefSeq Acc Id:

XR_010056898

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	58,033,873 - 58,055,061 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001381099	(Get FASTA)	NCBI Sequence Viewer
	NP_001381100	(Get FASTA)	NCBI Sequence Viewer
	NP_001381101	(Get FASTA)	NCBI Sequence Viewer
	XP_006250017	(Get FASTA)	NCBI Sequence Viewer
	XP_008767748	(Get FASTA)	NCBI Sequence Viewer
	XP_038946157	(Get FASTA)	NCBI Sequence Viewer
	XP_038946159	(Get FASTA)	NCBI Sequence Viewer
	XP_063128023	(Get FASTA)	NCBI Sequence Viewer
	XP_063128024	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79292	(Get FASTA)	NCBI Sequence Viewer
	EDM09605	(Get FASTA)	NCBI Sequence Viewer
	EDM09606	(Get FASTA)	NCBI Sequence Viewer
	EDM09607	(Get FASTA)	NCBI Sequence Viewer
	EDM09608	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000056811
	ENSRNOP00000056811.2
	ENSRNOP00000096477
	ENSRNOP00000096477.1
GenBank Protein	Q6AXW1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_006250017 ⟸ XM_006249955
- Peptide Label:	isoform X1
- UniProtKB:	Q6AXW1 (UniProtKB/Swiss-Prot), A6ICN9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSWYRAASVGRRLVASGRILAGRRGAAGAAGSGMGNSTSSFWGKSATTPVNQIQETISNNCVVI FSKSSCSYCSMAKKIFHDMNVNYKVVELDMVEYGSQFQEALYKMTGERTVPRIFVNGIFIGGAA DTHRLHKEGKLLPLVHQCYLNKSKRKDVE hide sequence

RefSeq Acc Id:	XP_008767748 ⟸ XM_008769526
- Peptide Label:	isoform X2
- UniProtKB:	A6ICP1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNSTSSFWGKSATTPVNQIQETISNNCVVIFSKSSCSYCSMAKKIFHDMNVNYKVVELDMVEY GSQFQEALYKMTGERTVPRIFVNGIFIGGAADTHRLHKEGKLLPLVHQCYLNKSKRKDVE hide sequence

Ensembl Acc Id:

ENSRNOP00000056811 ⟸ ENSRNOT00000060062

RefSeq Acc Id:	XP_038946157 ⟸ XM_039090229
- Peptide Label:	isoform X2
- UniProtKB:	A6ICP1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946159 ⟸ XM_039090231
- Peptide Label:	isoform X2
- UniProtKB:	A6ICP1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000096477 ⟸ ENSRNOT00000106322

RefSeq Acc Id:	NP_001381101 ⟸ NM_001394172
- Peptide Label:	2
- UniProtKB:	A6ICP1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001381099 ⟸ NM_001394170
- Peptide Label:	1
- UniProtKB:	Q6AXW1 (UniProtKB/Swiss-Prot), A6ICN9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001381100 ⟸ NM_001394171
- Peptide Label:	2
- UniProtKB:	A6ICP1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128023 ⟸ XM_063271953
- Peptide Label:	isoform X1
- UniProtKB:	Q6AXW1 (UniProtKB/Swiss-Prot), A6ICN9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128024 ⟸ XM_063271954
- Peptide Label:	isoform X2
- UniProtKB:	A6ICP1 (UniProtKB/TrEMBL)

Protein Domains

Glutaredoxin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AXW1-F1-model_v2	AlphaFold	Q6AXW1	1-157	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698872

Promoter ID:

EPDNEW_R9397

Type:

initiation region

Name:

Glrx2_1

Description:

glutaredoxin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	60,529,888 - 60,529,948	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307950	AgrOrtholog
BioCyc Gene	G2FUF-18027	BioCyc
Ensembl Genes	ENSRNOG00000003385	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000060062	ENTREZGENE
	ENSRNOT00000060062.5	UniProtKB/Swiss-Prot
	ENSRNOT00000106322	ENTREZGENE
	ENSRNOT00000106322.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Glutaredoxin	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7134405	IMAGE-MGC_LOAD
InterPro	Glutaredoxin	UniProtKB/Swiss-Prot
	Glutaredoxin_euk/vir	UniProtKB/Swiss-Prot
	Glutaredoxin_subgr	UniProtKB/Swiss-Prot
	Thioredoxin-like_sf	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94426	IMAGE-MGC_LOAD
NCBI Gene	114022	ENTREZGENE
PANTHER	GLUTAREDOXIN-2, MITOCHONDRIAL	UniProtKB/Swiss-Prot
	PTHR46679	UniProtKB/Swiss-Prot
Pfam	Glutaredoxin	UniProtKB/Swiss-Prot
PhenoGen	Glrx2	PhenoGen
PRINTS	GLUTAREDOXIN	UniProtKB/Swiss-Prot
PROSITE	GLUTAREDOXIN_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000003385	RatGTEx
Superfamily-SCOP	SSF52833	UniProtKB/Swiss-Prot
UniProt	A6ICN9	ENTREZGENE, UniProtKB/TrEMBL
	A6ICP0_RAT	UniProtKB/TrEMBL
	A6ICP1	ENTREZGENE, UniProtKB/TrEMBL
	A6ICP2_RAT	UniProtKB/TrEMBL
	GLRX2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-16	Glrx2	glutaredoxin 2	Glrx2	glutaredoxin 2 (thioltransferase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Glrx2	glutaredoxin 2 (thioltransferase)	Glrx2_predicted	glutaredoxin 2 (thioltransferase) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Glrx2_predicted	glutaredoxin 2 (thioltransferase) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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