Acss3 (acyl-CoA synthetase short-chain family member 3) - Rat Genome Database

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Gene: Acss3 (acyl-CoA synthetase short-chain family member 3) Rattus norvegicus
Analyze
Symbol: Acss3
Name: acyl-CoA synthetase short-chain family member 3
RGD ID: 1307051
Description: Enables acetate-CoA ligase activity; medium-chain fatty acid-CoA ligase activity; and propionate-CoA ligase activity. Predicted to be involved in lipid metabolic process. Located in mitochondrial matrix. Orthologous to human ACSS3 (acyl-CoA synthetase short chain family member 3); PARTICIPATES IN 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; fatty acid beta degradation pathway; malonic aciduria pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: acetate--CoA ligase 3; acyl-CoA synthetase short-chain family member 3, mitochondrial; hypothetical protein LOC314800; LOC314800; propionate--CoA ligase; RGD1307051; similar to hypothetical protein FLJ21963
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8744,127,725 - 44,336,707 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl744,127,122 - 44,336,684 (-)EnsemblGRCr8
mRatBN7.2742,241,261 - 42,450,209 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl742,242,652 - 42,450,230 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx744,173,696 - 44,355,183 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0746,376,772 - 46,558,269 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0746,154,652 - 46,336,112 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0749,047,022 - 49,250,953 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl749,047,013 - 49,250,957 (-)Ensemblrn6Rnor6.0
Rnor_5.0749,059,778 - 49,265,391 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4745,646,821 - 45,833,803 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera739,145,557 - 39,324,519 (-)NCBICelera
RGSC_v3.1745,642,178 - 45,853,987 (-)NCBI
Cytogenetic Map7q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
calcitriol  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDT  (EXP)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
flutamide  (EXP)
indometacin  (EXP)
lead(0)  (ISO)
mercury dichloride  (ISO)
Mesaconitine  (EXP)
methylmercury chloride  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phytoestrogen  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
trichloroethene  (EXP,ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrial matrix  (IBA,IDA,IEA,ISO)
mitochondrion  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Molecular cloning of rat acss3 and characterization of mammalian propionyl-CoA synthetase in the liver mitochondrial matrix. Yoshimura Y, etal., J Biochem. 2017 Mar 1;161(3):279-289. doi: 10.1093/jb/mvw067.
Additional References at PubMed
PMID:18614015  


Genomics

Comparative Map Data
Acss3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8744,127,725 - 44,336,707 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl744,127,122 - 44,336,684 (-)EnsemblGRCr8
mRatBN7.2742,241,261 - 42,450,209 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl742,242,652 - 42,450,230 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx744,173,696 - 44,355,183 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0746,376,772 - 46,558,269 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0746,154,652 - 46,336,112 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0749,047,022 - 49,250,953 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl749,047,013 - 49,250,957 (-)Ensemblrn6Rnor6.0
Rnor_5.0749,059,778 - 49,265,391 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4745,646,821 - 45,833,803 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera739,145,557 - 39,324,519 (-)NCBICelera
RGSC_v3.1745,642,178 - 45,853,987 (-)NCBI
Cytogenetic Map7q21NCBI
ACSS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381281,077,871 - 81,261,210 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1280,936,414 - 81,261,210 (+)Ensemblhg38GRCh38
GRCh371281,471,858 - 81,654,989 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361279,995,940 - 80,173,713 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1281,138,032 - 81,316,367 (+)NCBICelera
Cytogenetic Map12q21.31NCBI
HuRef1278,528,812 - 78,706,348 (+)NCBIHuRef
CHM1_11281,438,372 - 81,616,058 (+)NCBICHM1_1
T2T-CHM13v2.01281,056,837 - 81,240,187 (+)NCBIT2T-CHM13v2.0
Acss3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910106,769,375 - 106,959,622 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10106,769,378 - 106,959,529 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3810106,933,514 - 107,123,761 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10106,933,517 - 107,123,668 (-)Ensemblmm10GRCm38
MGSCv3710106,373,220 - 106,560,720 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610106,369,192 - 106,527,778 (-)NCBIMGSCv36mm8
Celera10108,877,696 - 109,072,448 (-)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.66NCBI
Acss3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540519,677,537 - 19,836,086 (+)Ensembl
ChiLan1.0NW_00495540519,677,191 - 19,836,086 (+)NCBIChiLan1.0ChiLan1.0
ACSS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21089,115,744 - 89,300,534 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11289,110,389 - 89,291,091 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01278,586,987 - 78,771,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11281,698,782 - 81,878,325 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1281,698,875 - 81,878,325 (+)EnsemblpanPan2panpan1.1
ACSS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11523,337,386 - 23,480,766 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1523,338,432 - 23,478,593 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1523,761,776 - 23,904,041 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01523,699,143 - 23,842,034 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1523,699,019 - 23,841,651 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11523,276,355 - 23,427,464 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01523,336,248 - 23,478,319 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01523,576,616 - 23,719,097 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Acss3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494536,823,381 - 36,982,797 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366981,929,683 - 2,089,228 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366981,929,683 - 2,089,703 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACSS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5100,279,698 - 100,429,165 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.15100,272,255 - 100,429,229 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25105,195,329 - 105,368,501 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACSS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11176,563,595 - 76,737,014 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1176,563,668 - 76,736,852 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037168,686,420 - 168,867,257 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acss3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624837416,028 - 625,885 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624837416,779 - 626,097 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Acss3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11185,198,421 - 185,384,040 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Acss3
1506 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:72
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000066975
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)72154197751639954Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)72154197751639954Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74299622658678836Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 26 59 6 290 126 11 140 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000066975   ⟹   ENSRNOP00000062459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl744,155,294 - 44,336,684 (-)Ensembl
mRatBN7.2 Ensembl742,268,832 - 42,450,230 (-)Ensembl
Rnor_6.0 Ensembl749,074,595 - 49,250,953 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082141   ⟹   ENSRNOP00000071300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl744,127,725 - 44,336,684 (-)Ensembl
mRatBN7.2 Ensembl742,242,652 - 42,450,230 (-)Ensembl
Rnor_6.0 Ensembl749,047,013 - 49,250,957 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000144890   ⟹   ENSRNOP00000100819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl744,127,122 - 44,336,684 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000147339   ⟹   ENSRNOP00000105212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl744,127,725 - 44,336,684 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000170933   ⟹   ENSRNOP00000110613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl744,127,725 - 44,336,684 (-)Ensembl
RefSeq Acc Id: NM_001108091   ⟹   NP_001101561
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8744,155,294 - 44,336,684 (-)NCBI
mRatBN7.2742,268,832 - 42,450,209 (-)NCBI
Rnor_6.0749,074,595 - 49,250,953 (-)NCBI
Rnor_5.0749,059,778 - 49,265,391 (-)NCBI
RGSC_v3.4745,646,821 - 45,833,803 (-)RGD
Celera739,145,557 - 39,324,519 (-)RGD
Sequence:
RefSeq Acc Id: NM_001414941   ⟹   NP_001401870
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8744,127,725 - 44,336,684 (-)NCBI
mRatBN7.2742,241,261 - 42,450,209 (-)NCBI
RefSeq Acc Id: XM_006241303   ⟹   XP_006241365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8744,127,725 - 44,335,568 (-)NCBI
mRatBN7.2742,241,261 - 42,443,971 (-)NCBI
Rnor_6.0749,047,022 - 49,244,691 (-)NCBI
Rnor_5.0749,059,778 - 49,265,391 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079107   ⟹   XP_038935035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8744,127,725 - 44,336,238 (-)NCBI
mRatBN7.2742,241,261 - 42,449,761 (-)NCBI
RefSeq Acc Id: XM_039079108   ⟹   XP_038935036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8744,180,740 - 44,336,707 (-)NCBI
mRatBN7.2742,294,264 - 42,450,209 (-)NCBI
RefSeq Acc Id: NP_001101561   ⟸   NM_001108091
- Peptide Label: isoform 2
- UniProtKB: D3ZGU2 (UniProtKB/TrEMBL),   A6IGC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241365   ⟸   XM_006241303
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000071300   ⟸   ENSRNOT00000082141
Ensembl Acc Id: ENSRNOP00000062459   ⟸   ENSRNOT00000066975
RefSeq Acc Id: XP_038935035   ⟸   XM_039079107
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038935036   ⟸   XM_039079108
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001401870   ⟸   NM_001414941
- Peptide Label: isoform 1
- UniProtKB: A0A0G2K047 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000100819   ⟸   ENSRNOT00000144890
Ensembl Acc Id: ENSRNOP00000105212   ⟸   ENSRNOT00000147339
Ensembl Acc Id: ENSRNOP00000110613   ⟸   ENSRNOT00000170933
Protein Domains
Acetyl-coenzyme A synthetase N-terminal   AMP-dependent synthetase/ligase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K047-F1-model_v2 AlphaFold A0A0G2K047 1-683 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695179
Promoter ID:EPDNEW_R5704
Type:initiation region
Name:Acss3_1
Description:acyl-CoA synthetase short-chain family member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0749,250,877 - 49,250,937EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307051 AgrOrtholog
BioCyc Gene G2FUF-34184 BioCyc
Ensembl Genes ENSRNOG00000004448 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000066975 ENTREZGENE
  ENSRNOT00000082141 ENTREZGENE
  ENSRNOT00000082141.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.300.30 UniProtKB/Swiss-Prot
  3.40.50.12780 UniProtKB/Swiss-Prot
InterPro ACAS_N UniProtKB/Swiss-Prot
  AMP-bd_C UniProtKB/Swiss-Prot
  AMP-bd_C_sf UniProtKB/Swiss-Prot
  AMP-binding_CS UniProtKB/Swiss-Prot
  AMP-dep_Synth/Lig UniProtKB/Swiss-Prot
  AMP-dep_Synthh-like_sf UniProtKB/Swiss-Prot
NCBI Gene 314800 ENTREZGENE
PANTHER ACYL-COA SYNTHETASE UniProtKB/Swiss-Prot
  ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam ACAS_N UniProtKB/Swiss-Prot
  AMP-binding UniProtKB/Swiss-Prot
  AMP-binding_C UniProtKB/Swiss-Prot
PhenoGen Acss3 PhenoGen
PROSITE AMP_BINDING UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004448 RatGTEx
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/Swiss-Prot
UniProt A0A0G2K047 ENTREZGENE
  A0ABK0LCH9_RAT UniProtKB/TrEMBL
  A0ABK0LI85_RAT UniProtKB/TrEMBL
  A0ABK0LN91_RAT UniProtKB/TrEMBL
  A6IGC2 ENTREZGENE, UniProtKB/TrEMBL
  ACSS3_RAT UniProtKB/Swiss-Prot
  D3ZGU2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-05-26 Acss3  acyl-CoA synthetase short-chain family member 3  RGD1307051  similar to hypothetical protein FLJ21963  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1307051  similar to hypothetical protein FLJ21963   RGD1307051_predicted  similar to hypothetical protein FLJ21963 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1307051_predicted  similar to hypothetical protein FLJ21963 (predicted)  LOC314800_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314800_predicted  similar to hypothetical protein FLJ21963 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL