Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Lonp2 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Lonp2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine affects the expression of LONP2 mRNA | CTD | PMID:22206623 | Lonp2 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of LONP2 mRNA | CTD | PMID:17108234 | Lonp2 | Rat | 17beta-estradiol | increases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Estradiol results in increased expression of LONP2 mRNA | CTD | PMID:39298647 | Lonp2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of LONP2 mRNA | CTD | PMID:31826744 | Lonp2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Lonp2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LONP2 mRNA | CTD | PMID:21570461 | Lonp2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LONP2 mRNA | CTD | PMID:21215274 | Lonp2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Lonp2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of LONP2 mRNA | CTD | PMID:16214954 | Lonp2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Lonp2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of LONP2 mRNA | CTD | PMID:39298647 | Lonp2 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | LONP2 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of LONP2 gene | CTD | PMID:31601247 | Lonp2 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of LONP2 mRNA | CTD | PMID:31881176 | Lonp2 | Rat | acrylamide | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of LONP2 mRNA | CTD | PMID:32763439 | Lonp2 | Rat | aflatoxin B1 | decreases methylation | ISO | LONP2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of LONP2 gene | CTD | PMID:27153756 | Lonp2 | Rat | aldrin | increases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Aldrin results in increased expression of LONP2 mRNA | CTD | PMID:18579281 | Lonp2 | Rat | aristolochic acid A | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of LONP2 mRNA | CTD | PMID:33212167 | Lonp2 | Rat | arsane | affects methylation | ISO | LONP2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of LONP2 gene | CTD | PMID:25304211 | Lonp2 | Rat | arsenic atom | affects methylation | ISO | LONP2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of LONP2 gene | CTD | PMID:25304211 | Lonp2 | Rat | benzo[a]pyrene | multiple interactions | ISO | Lonp2 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of LONP2 mRNA] | CTD | PMID:22228805 | Lonp2 | Rat | benzo[a]pyrene | affects methylation | ISO | LONP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LONP2 promoter | CTD | PMID:27901495 | Lonp2 | Rat | benzo[a]pyrene | increases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of LONP2 mRNA | CTD | PMID:22228805 | Lonp2 | Rat | benzo[a]pyrene | decreases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of LONP2 mRNA | CTD | PMID:20127859 | Lonp2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of LONP2 mRNA | CTD | PMID:19150397|PMID:20018196 | Lonp2 | Rat | benzo[e]pyrene | increases methylation | ISO | LONP2 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of LONP2 polyA tail | CTD | PMID:30157460 | Lonp2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of LONP2 protein | CTD | PMID:17929048 | Lonp2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LONP2 mRNA | CTD | PMID:25181051 | Lonp2 | Rat | bisphenol A | multiple interactions | ISO | LONP2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] affects the methylation of LONP2 gene | CTD | PMID:31601247 | Lonp2 | Rat | bisphenol A | affects methylation | ISO | LONP2 (Homo sapiens) | 6480464 | bisphenol A affects the methylation of LONP2 gene | CTD | PMID:31601247 | Lonp2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LONP2 mRNA | CTD | PMID:30816183|PMID:32528016|PMID:34947998 | Lonp2 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of LONP2 gene | CTD | PMID:28505145 | Lonp2 | Rat | bisphenol F | increases expression | ISO | Lonp2 (Mus musculus) | 6480464 | bisphenol F results in increased expression of LONP2 mRNA | CTD | PMID:38685157 | Lonp2 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Lonp2 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of LONP2 intron | CTD | PMID:28392331 | Lonp2 | Rat | caffeine | decreases phosphorylation | ISO | LONP2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of LONP2 protein | CTD | PMID:35688186 | Lonp2 | Rat | carbamazepine | affects expression | ISO | LONP2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of LONP2 mRNA | CTD | PMID:25979313 | Lonp2 | Rat | cisplatin | increases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of LONP2 mRNA | CTD | PMID:27392435 | Lonp2 | Rat | clofibrate | multiple interactions | ISO | Lonp2 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of LONP2 mRNA; PPARA affects the reaction [[Clofibrate more ... | CTD | PMID:17585979 | Lonp2 | Rat | clofibrate | increases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Clofibrate results in increased expression of LONP2 mRNA | CTD | PMID:17585979|PMID:23811191 | Lonp2 | Rat | cyclosporin A | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of LONP2 mRNA | CTD | PMID:20106945 | Lonp2 | Rat | cyclosporin A | decreases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of LONP2 mRNA | CTD | PMID:19770486 | Lonp2 | Rat | Dibutyl phosphate | affects expression | ISO | LONP2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of LONP2 mRNA | CTD | PMID:37042841 | Lonp2 | Rat | dorsomorphin | multiple interactions | ISO | LONP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lonp2 | Rat | fenthion | decreases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Fenthion results in decreased expression of LONP2 mRNA | CTD | PMID:34813904 | Lonp2 | Rat | fulvestrant | multiple interactions | ISO | LONP2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] affects the methylation of LONP2 gene | CTD | PMID:31601247 | Lonp2 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of LONP2 mRNA | CTD | PMID:24136188 | Lonp2 | Rat | ivermectin | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of LONP2 protein | CTD | PMID:32959892 | Lonp2 | Rat | lead(0) | affects methylation | ISO | LONP2 (Homo sapiens) | 6480464 | Lead affects the methylation of LONP2 gene | CTD | PMID:31636367 | Lonp2 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of LONP2 mRNA | CTD | PMID:30467583 | Lonp2 | Rat | methapyrilene | increases methylation | ISO | LONP2 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of LONP2 polyA tail | CTD | PMID:30157460 | Lonp2 | Rat | methidathion | affects expression | ISO | Lonp2 (Mus musculus) | 6480464 | methidathion affects the expression of LONP2 mRNA | CTD | PMID:34813904 | Lonp2 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of LONP2 gene | CTD | PMID:35440735 | Lonp2 | Rat | methyl methanesulfonate | increases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of LONP2 mRNA | CTD | PMID:23649840 | Lonp2 | Rat | Muraglitazar | increases expression | EXP | | 6480464 | muraglitazar results in increased expression of LONP2 mRNA | CTD | PMID:21515302 | Lonp2 | Rat | nitrates | multiple interactions | ISO | Lonp2 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of LONP2 more ... | CTD | PMID:35964746 | Lonp2 | Rat | paracetamol | affects expression | ISO | Lonp2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LONP2 mRNA | CTD | PMID:17562736 | Lonp2 | Rat | paracetamol | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of LONP2 mRNA | CTD | PMID:21420995|PMID:29067470 | Lonp2 | Rat | paracetamol | multiple interactions | ISO | Lonp2 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of LONP2 mRNA; PPARA affects the reaction [[Clofibrate more ... | CTD | PMID:17585979 | Lonp2 | Rat | phenobarbital | affects expression | ISO | Lonp2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of LONP2 mRNA | CTD | PMID:23091169 | Lonp2 | Rat | phenylmercury acetate | multiple interactions | ISO | LONP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lonp2 | Rat | pirinixic acid | multiple interactions | ISO | Lonp2 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Lonp2 | Rat | pirinixic acid | increases expression | ISO | Lonp2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of LONP2 mRNA | CTD | PMID:17426115|PMID:20813756|PMID:23811191 | Lonp2 | Rat | propiconazole | decreases expression | ISO | Lonp2 (Mus musculus) | 6480464 | propiconazole results in decreased expression of LONP2 mRNA | CTD | PMID:21278054 | Lonp2 | Rat | resveratrol | multiple interactions | ISO | LONP2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of LONP2 mRNA | CTD | PMID:23557933 | Lonp2 | Rat | rotenone | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of LONP2 protein | CTD | PMID:39603559 | Lonp2 | Rat | SB 431542 | multiple interactions | ISO | LONP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lonp2 | Rat | sodium arsenate | increases expression | ISO | Lonp2 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of LONP2 mRNA | CTD | PMID:21795629 | Lonp2 | Rat | sodium arsenate | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | sodium arsenate results in decreased expression of LONP2 protein | CTD | PMID:38348393 | Lonp2 | Rat | sodium fluoride | decreases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of LONP2 protein | CTD | PMID:28918527 | Lonp2 | Rat | temozolomide | decreases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of LONP2 mRNA | CTD | PMID:31758290 | Lonp2 | Rat | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of LONP2 mRNA | CTD | PMID:21515302 | Lonp2 | Rat | tetrachloromethane | decreases expression | ISO | Lonp2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of LONP2 mRNA | CTD | PMID:31919559 | Lonp2 | Rat | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of LONP2 protein | CTD | PMID:35544339 | Lonp2 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of LONP2 mRNA | CTD | PMID:34492290 | Lonp2 | Rat | trichostatin A | increases expression | ISO | LONP2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of LONP2 mRNA | CTD | PMID:24935251 | Lonp2 | Rat | triphenyl phosphate | affects expression | ISO | LONP2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of LONP2 mRNA | CTD | PMID:37042841 | Lonp2 | Rat | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of LONP2 mRNA | CTD | PMID:21515302 | Lonp2 | Rat | uranium atom | increases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Uranium results in increased expression of LONP2 mRNA | CTD | PMID:15672453 | Lonp2 | Rat | valproic acid | increases expression | ISO | LONP2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LONP2 mRNA | CTD | PMID:23179753|PMID:24935251 | Lonp2 | Rat | valproic acid | affects expression | ISO | Lonp2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of LONP2 mRNA | CTD | PMID:17963808 | Lonp2 | Rat | valproic acid | affects expression | ISO | LONP2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of LONP2 mRNA | CTD | PMID:25979313 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















