Farp1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) - Rat Genome Database

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Gene: Farp1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) Rattus norvegicus
Analyze
Symbol: Farp1
Name: FERM, ARH/RhoGEF and pleckstrin domain protein 1
RGD ID: 1305346
Description: Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including dendrite morphogenesis; retrograde trans-synaptic signaling by trans-synaptic protein complex; and synapse organization. Located in cytoplasmic side of plasma membrane; cytosol; and dendrite. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic membrane. Orthologous to human FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FERM, ARHGEF and pleckstrin domain-containing protein 1; FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived); FERM, RhoGEF and pleckstrin domain-containing protein 1; FERMRhoGEF (Arhgef) and pleckstrin domain protein 1-like; LOC306183
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,531,196 - 104,770,148 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl15104,531,813 - 104,770,147 (+)EnsemblGRCr8
mRatBN7.21598,124,304 - 98,363,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx15102,114,666 - 102,296,077 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015103,216,836 - 103,397,759 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.015100,143,970 - 100,325,367 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.015106,375,298 - 106,625,837 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,434,177 - 106,625,837 (+)Ensemblrn6Rnor6.0
Rnor_5.015109,772,475 - 110,020,013 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.415106,171,848 - 106,253,441 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1596,990,113 - 97,147,686 (+)NCBICelera
RGSC_v3.115106,132,880 - 106,268,432 (+)NCBI
Cytogenetic Map15q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
allethrin  (EXP)
amosite asbestos  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
chrysene  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
fonofos  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glyphosate  (EXP)
hexamethylene diisocyanate  (ISO)
inulin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
pyrethrins  (EXP)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulforaphane  (ISO)
terbufos  (ISO)
tert-butyl hydroperoxide  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organization. Cheadle L and Biederer T, J Cell Biol. 2012 Dec 10;199(6):985-1001. doi: 10.1083/jcb.201205041. Epub 2012 Dec 3.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19389623   PMID:24899721  


Genomics

Comparative Map Data
Farp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,531,196 - 104,770,148 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl15104,531,813 - 104,770,147 (+)EnsemblGRCr8
mRatBN7.21598,124,304 - 98,363,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx15102,114,666 - 102,296,077 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015103,216,836 - 103,397,759 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.015100,143,970 - 100,325,367 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.015106,375,298 - 106,625,837 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,434,177 - 106,625,837 (+)Ensemblrn6Rnor6.0
Rnor_5.015109,772,475 - 110,020,013 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.415106,171,848 - 106,253,441 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1596,990,113 - 97,147,686 (+)NCBICelera
RGSC_v3.115106,132,880 - 106,268,432 (+)NCBI
Cytogenetic Map15q24NCBI
FARP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381398,142,589 - 98,455,176 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1398,142,165 - 98,455,176 (+)Ensemblhg38GRCh38
GRCh371398,794,843 - 99,107,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361397,593,435 - 97,900,024 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341397,593,434 - 97,900,022NCBI
Celera1379,642,528 - 79,949,414 (+)NCBICelera
Cytogenetic Map13q32.2NCBI
HuRef1379,393,341 - 79,700,014 (+)NCBIHuRef
CHM1_11398,765,676 - 99,072,533 (+)NCBICHM1_1
T2T-CHM13v2.01397,349,662 - 97,662,977 (+)NCBIT2T-CHM13v2.0
Farp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914121,272,563 - 121,521,156 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14121,272,612 - 121,521,156 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3814121,035,168 - 121,283,744 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14121,035,200 - 121,283,744 (+)Ensemblmm10GRCm38
MGSCv3714121,434,796 - 121,682,948 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3614120,237,254 - 120,420,973 (+)NCBIMGSCv36mm8
Celera14119,647,443 - 119,834,111 (+)NCBICelera
Cytogenetic Map14E5NCBI
cM Map1464.86NCBI
Farp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540412,051,591 - 12,317,035 (-)Ensembl
ChiLan1.0NW_00495540412,050,225 - 12,316,842 (-)NCBIChiLan1.0ChiLan1.0
FARP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21499,657,079 - 99,968,975 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11398,326,502 - 98,641,059 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01379,300,995 - 79,615,649 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11398,452,203 - 98,762,514 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1398,522,235 - 98,761,085 (+)EnsemblpanPan2panpan1.1
FARP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12248,284,961 - 48,575,007 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2248,342,521 - 48,573,836 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2248,071,250 - 48,356,468 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02248,731,985 - 49,017,180 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2248,732,020 - 49,017,177 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12248,382,095 - 48,667,283 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02248,416,215 - 48,701,436 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02248,452,007 - 48,737,927 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Farp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945183,796,523 - 184,060,923 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647211,887,767 - 12,100,242 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647211,891,234 - 12,100,202 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FARP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1167,144,645 - 67,457,548 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11167,144,622 - 67,457,547 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21174,553,756 - 74,694,542 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FARP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1376,807,172 - 77,102,146 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl376,807,211 - 77,100,720 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604633,286,663 - 33,585,234 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Farp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479312,592,574 - 12,796,155 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479312,595,521 - 12,870,803 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Farp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1123,598,207 - 3,671,454 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:217
Count of miRNA genes:152
Interacting mature miRNAs:191
Transcripts:ENSRNOT00000015271
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)1560213984105213984Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1582194914108192169Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1574735564106469153Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1588677086104695021Rat
1358354Srcrt5Stress Responsive Cort QTL 53.38blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1582503470108192169Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1582714037106778197Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)1588677086104695021Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1564571127108192169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
7411646Foco21Food consumption QTL 2123.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1584278281108192169Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)1561710951106710951Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)1583700787108192169Rat
2313080Bss65Bone structure and strength QTL 653.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1567399137108192169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1582194914108192169Rat

Markers in Region
D15Rat106  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr815104,694,807 - 104,695,021 (+)Marker Load Pipeline
mRatBN7.21598,287,955 - 98,288,169 (+)MAPPERmRatBN7.2
Rnor_6.015106,550,444 - 106,550,657NCBIRnor6.0
Rnor_5.015109,944,744 - 109,944,957UniSTSRnor5.0
RGSC_v3.415106,177,703 - 106,177,917RGDRGSC3.4
RGSC_v3.415106,177,704 - 106,177,917UniSTSRGSC3.4
Celera1597,072,390 - 97,072,603UniSTS
RGSC_v3.115106,193,484 - 106,193,697RGD
RH 3.4 Map15688.5RGD
RH 3.4 Map15688.5UniSTS
SHRSP x BN Map1565.3898RGD
SHRSP x BN Map1565.3898UniSTS
FHH x ACI Map1574.04RGD
Cytogenetic Map15q24-q25UniSTS
AW228844  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,362,898 - 98,362,996 (+)MAPPERmRatBN7.2
Rnor_6.015106,625,437 - 106,625,534NCBIRnor6.0
Rnor_5.015110,019,613 - 110,019,710UniSTSRnor5.0
RGSC_v3.415106,253,041 - 106,253,138UniSTSRGSC3.4
Celera1597,147,286 - 97,147,383UniSTS
Cytogenetic Map15q24-q25UniSTS
BE116755  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,307,851 - 98,308,028 (+)MAPPERmRatBN7.2
Rnor_6.015106,570,339 - 106,570,515NCBIRnor6.0
Rnor_5.015109,964,515 - 109,964,691UniSTSRnor5.0
RGSC_v3.415106,198,014 - 106,198,190UniSTSRGSC3.4
Celera1597,092,171 - 97,092,347UniSTS
RH 3.4 Map15691.5UniSTS
Cytogenetic Map15q24-q25UniSTS
RH138289  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,329,592 - 98,329,768 (+)MAPPERmRatBN7.2
Rnor_6.015106,592,079 - 106,592,254NCBIRnor6.0
Rnor_5.015109,986,255 - 109,986,430UniSTSRnor5.0
RGSC_v3.415106,219,753 - 106,219,928UniSTSRGSC3.4
Celera1597,113,923 - 97,114,098UniSTS
RH 3.4 Map15690.3UniSTS
Cytogenetic Map15q24-q25UniSTS
RH139121  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,327,184 - 98,327,340 (+)MAPPERmRatBN7.2
Rnor_6.015106,589,670 - 106,589,825NCBIRnor6.0
Rnor_5.015109,983,846 - 109,984,001UniSTSRnor5.0
RGSC_v3.415106,217,345 - 106,217,500UniSTSRGSC3.4
Celera1597,111,515 - 97,111,670UniSTS
RH 3.4 Map15690.21UniSTS
Cytogenetic Map15q24-q25UniSTS
RH139138  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,330,204 - 98,330,453 (+)MAPPERmRatBN7.2
Rnor_6.015106,592,691 - 106,592,939NCBIRnor6.0
Rnor_5.015109,986,867 - 109,987,115UniSTSRnor5.0
RGSC_v3.415106,220,365 - 106,220,613UniSTSRGSC3.4
Celera1597,114,535 - 97,114,783UniSTS
RH 3.4 Map15738.99UniSTS
Cytogenetic Map15q24-q25UniSTS
RH141737  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,362,040 - 98,362,222 (+)MAPPERmRatBN7.2
Rnor_6.015106,624,579 - 106,624,760NCBIRnor6.0
Rnor_5.015110,018,755 - 110,018,936UniSTSRnor5.0
RGSC_v3.415106,252,183 - 106,252,364UniSTSRGSC3.4
Celera1597,146,428 - 97,146,609UniSTS
RH 3.4 Map15691.3UniSTS
Cytogenetic Map15q24-q25UniSTS
AI229437  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,215,978 - 98,216,160 (+)MAPPERmRatBN7.2
Rnor_6.015106,468,712 - 106,468,893NCBIRnor6.0
Rnor_5.015109,863,239 - 109,863,420UniSTSRnor5.0
Celera1597,023,167 - 97,023,348UniSTS
RH 3.4 Map15689.0UniSTS
Cytogenetic Map15q24-q25UniSTS
BE107531  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,240,781 - 98,240,931 (+)MAPPERmRatBN7.2
Rnor_6.015106,493,387 - 106,493,536NCBIRnor6.0
Rnor_5.015109,887,914 - 109,888,063UniSTSRnor5.0
Celera1597,047,967 - 97,048,116UniSTS
RH 3.4 Map15690.9UniSTS
Cytogenetic Map15q24-q25UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 83 59 6 347 183 11 141 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000015271   ⟹   ENSRNOP00000015271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15104,531,813 - 104,770,147 (+)Ensembl
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)Ensembl
Rnor_6.0 Ensembl15106,434,177 - 106,625,837 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098108   ⟹   ENSRNOP00000080871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl15104,531,813 - 104,770,147 (+)Ensembl
mRatBN7.2 Ensembl1598,182,329 - 98,363,299 (+)Ensembl
RefSeq Acc Id: NM_001107287   ⟹   NP_001100757
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,589,185 - 104,770,148 (+)NCBI
mRatBN7.21598,182,329 - 98,363,299 (+)NCBI
Rnor_6.015106,434,177 - 106,625,837 (+)NCBI
Rnor_5.015109,772,475 - 110,020,013 (+)NCBI
RGSC_v3.415106,171,848 - 106,253,441 (+)RGD
Celera1596,990,113 - 97,147,686 (+)RGD
Sequence:
RefSeq Acc Id: XM_006252472   ⟹   XP_006252534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,531,836 - 104,770,146 (+)NCBI
mRatBN7.21598,124,973 - 98,363,298 (+)NCBI
Rnor_6.015106,376,421 - 106,625,836 (+)NCBI
Rnor_5.015109,772,475 - 110,020,013 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006252475   ⟹   XP_006252537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,531,836 - 104,770,146 (+)NCBI
mRatBN7.21598,124,973 - 98,363,298 (+)NCBI
Rnor_6.015106,376,421 - 106,625,836 (+)NCBI
Rnor_5.015109,772,475 - 110,020,013 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599720   ⟹   XP_017455209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,531,196 - 104,770,146 (+)NCBI
mRatBN7.21598,124,304 - 98,363,298 (+)NCBI
Rnor_6.015106,375,298 - 106,625,836 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063274357   ⟹   XP_063130427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,733,523 - 104,770,146 (+)NCBI
RefSeq Acc Id: XM_063274358   ⟹   XP_063130428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815104,733,523 - 104,770,146 (+)NCBI
RefSeq Acc Id: NP_001100757   ⟸   NM_001107287
- UniProtKB: F1LYQ8 (UniProtKB/Swiss-Prot),   A0A8I5ZQU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252534   ⟸   XM_006252472
- Peptide Label: isoform X1
- UniProtKB: F1LYQ8 (UniProtKB/Swiss-Prot),   A0A8I5ZQU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252537   ⟸   XM_006252475
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZQU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455209   ⟸   XM_017599720
- Peptide Label: isoform X1
- UniProtKB: F1LYQ8 (UniProtKB/Swiss-Prot),   A0A8I5ZQU0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015271   ⟸   ENSRNOT00000015271
Ensembl Acc Id: ENSRNOP00000080871   ⟸   ENSRNOT00000098108
RefSeq Acc Id: XP_063130427   ⟸   XM_063274357
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063130428   ⟸   XM_063274358
- Peptide Label: isoform X4
Protein Domains
DH   FERM   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LYQ8-F1-model_v2 AlphaFold F1LYQ8 1-1049 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305346 AgrOrtholog
BioCyc Gene G2FUF-12380 BioCyc
Ensembl Genes ENSRNOG00000011203 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015271 ENTREZGENE
  ENSRNOT00000015271.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.80.10 UniProtKB/Swiss-Prot
  1.20.900.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
InterPro Band_41_domain UniProtKB/Swiss-Prot
  DBL_dom_sf UniProtKB/Swiss-Prot
  DH-domain UniProtKB/Swiss-Prot
  Ez/rad/moesin-like UniProtKB/Swiss-Prot
  FARP1/FARP2/FRMD7_FERM_C UniProtKB/Swiss-Prot
  FERM-adjacent UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_CS UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  FERM_PH-like_C UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
  RAC1-GEF UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report rno:306183 UniProtKB/Swiss-Prot
NCBI Gene 306183 ENTREZGENE
PANTHER FERM DOMAIN CONTAINING PROTEIN UniProtKB/Swiss-Prot
  FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot
Pfam FERM_C UniProtKB/Swiss-Prot
  FERM_M UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  PF00169 UniProtKB/Swiss-Prot
  PF08736 UniProtKB/Swiss-Prot
  RhoGEF UniProtKB/Swiss-Prot
PhenoGen Farp1 PhenoGen
PRINTS BAND41 UniProtKB/Swiss-Prot
  ERMFAMILY UniProtKB/Swiss-Prot
PROSITE DH_2 UniProtKB/Swiss-Prot
  FERM_1 UniProtKB/Swiss-Prot
  FERM_3 UniProtKB/Swiss-Prot
  PH_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011203 RatGTEx
SMART B41 UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
  RhoGEF UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot
  SM01195 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF47031 UniProtKB/Swiss-Prot
  SSF48065 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
UniProt A0A8I5ZQU0 ENTREZGENE, UniProtKB/TrEMBL
  F1LYQ8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Farp1  FERM, ARH/RhoGEF and pleckstrin domain protein 1  Farp1  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Farp1  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)  LOC100361560  FERMRhoGEF (Arhgef) and pleckstrin domain protein 1-like  Data merged from RGD:2319908 1643240 APPROVED
2010-05-05 LOC100361560  FERMRhoGEF (Arhgef) and pleckstrin domain protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Farp1  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)   Farp1_predicted  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Farp1_predicted  FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) (predicted)      Symbol and Name status set to approved 70820 APPROVED